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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
LWIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDR
ISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPE
SHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVD
PEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAA
QELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREK
GFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHST
GKSSQRQMVFGVVTAIDLLNFVAAQER

The query sequence (length=507) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 8s5h:A 507 507 1.0000 1.0000 1.0000 0.0 4coo:A, 4coo:B, 1jbq:A, 1jbq:B, 1jbq:C, 1jbq:D, 1jbq:E, 1jbq:F, 4l0d:A, 4l0d:B, 4l27:B, 4l27:D, 4l27:A, 4l27:C, 4l28:A, 4l28:B, 4l28:C, 4l28:D, 4l3v:B, 4l3v:A, 4l3v:C, 1m54:A, 1m54:B, 1m54:C, 1m54:D, 1m54:E, 1m54:F, 5mms:A, 5mms:F, 5mms:B, 5mms:C, 5mms:D, 5mms:E, 4pcu:A, 4pcu:B, 7qgt:A, 7qgt:B, 8s5h:B, 8s5h:C, 8s5h:D, 8s5h:E, 8s5h:F, 8s5h:G, 8s5h:H, 8s5i:A, 8s5i:B, 8s5i:C, 8s5i:D, 8s5i:E, 8s5i:F, 8s5j:A, 8s5j:B, 8s5j:C, 8s5j:D, 8s5j:E, 8s5j:F, 8s5j:G, 8s5j:H, 8s5j:I, 8s5j:J, 8s5k:A, 8s5k:B, 8s5k:C, 8s5k:D, 8s5k:E, 8s5k:F, 8s5k:G, 8s5k:H, 8s5l:A, 8s5l:B, 8s5l:C, 8s5l:D, 8s5m:A, 8s5m:B, 8s5m:C, 8s5m:D, 8s5m:E, 8s5m:F, 8s5m:G, 8s5m:H, 8s5m:I, 8s5m:J, 8stw:A, 8stw:B, 8stw:C, 8stw:D, 8stw:E, 8stw:F, 4uuu:A, 4uuu:B
2 3pc3:A 504 505 0.5207 0.5238 0.5228 1.03e-173 3pc2:A, 3pc4:A
3 5ohx:A 488 502 0.4990 0.5184 0.5040 4.56e-167 5ohx:B
4 6xwl:C 477 483 0.4477 0.4759 0.4700 1.29e-146 6xwl:F, 6xwl:A, 6xwl:B, 6xwl:D, 6xwl:E, 6xyl:A, 6xyl:B, 6xyl:C, 6xyl:D, 6xyl:E, 6xyl:F, 6y21:D, 6y21:A, 6y21:B, 6z3s:D, 6z3s:A, 6z3s:B, 6zs7:D, 6zs7:A, 6zs7:B, 6zs7:C, 6zs7:E, 6zs7:F
5 6vju:B 317 322 0.3807 0.6088 0.5994 6.31e-123
6 6c2h:A 345 333 0.3452 0.5072 0.5255 2.65e-119 6c2q:A, 6c2z:A, 6c4p:A
7 7xnz:B 458 473 0.3708 0.4105 0.3975 1.58e-84 7xnz:A, 7xnz:C, 7xnz:D, 7xoh:B, 7xoh:A, 7xoh:C, 7xoh:D, 7xoy:B, 7xoy:A, 7xoy:C, 7xoy:D
8 6ahi:B 306 301 0.2426 0.4020 0.4086 4.17e-72
9 2q3d:A 306 312 0.2525 0.4183 0.4103 3.40e-64 2q3c:A, 3zei:A
10 4lma:A 318 314 0.2446 0.3899 0.3949 2.11e-60 4lma:B
11 2eco:A 302 302 0.2505 0.4205 0.4205 3.68e-60 2ecq:A, 2efy:A, 2efy:B, 1ve1:A
12 4lmb:A 310 310 0.2426 0.3968 0.3968 2.07e-58
13 7n2t:A 309 314 0.2525 0.4142 0.4076 1.63e-57
14 2isq:A 320 317 0.2426 0.3844 0.3880 1.49e-56 1z7w:A, 1z7y:A
15 4aec:A 323 314 0.2505 0.3932 0.4045 7.26e-56 4aec:B
16 5xoq:A 310 313 0.2544 0.4161 0.4121 2.48e-55 5xoq:B
17 7mfj:BBB 319 314 0.2189 0.3480 0.3535 6.85e-55
18 5b1i:A 303 315 0.2327 0.3894 0.3746 1.80e-54 5b1i:B, 5b1i:C, 5b1i:D, 5b1i:E, 5b1i:F, 5b1i:G, 5b1i:H
19 3x44:A 321 319 0.2327 0.3676 0.3699 6.84e-53 3x43:A, 3x43:B, 3x43:C, 3x43:D, 3x43:E, 3x43:F, 3x43:G, 3x43:H, 3x44:B
20 5xem:A 302 307 0.2288 0.3841 0.3779 2.32e-52 5xem:B, 5xen:A, 5xen:B, 5xeo:A, 5xeo:B
21 2bht:A 294 288 0.2130 0.3673 0.3750 4.83e-52 2bhs:A, 2bhs:B, 2bhs:C, 2bhs:D, 2bht:B, 2bht:C, 2bht:D, 2jc3:A, 2jc3:H, 2jc3:B, 2jc3:C, 2jc3:D, 2jc3:E, 2jc3:F, 2jc3:G, 2v03:A
22 3bm5:A 338 315 0.2268 0.3402 0.3651 3.89e-51 3bm5:B, 4il5:A, 4jbl:B, 4jbn:A, 2pqm:A, 2pqm:B
23 3vbe:C 329 317 0.2170 0.3343 0.3470 1.31e-49 3vbe:A, 3vbe:B, 3vbe:D, 3vc3:A, 3vc3:B, 3vc3:C, 3vc3:D, 3vc3:E, 3vc3:F
24 5d84:A 318 314 0.1992 0.3176 0.3217 2.07e-49 5d85:A, 5d86:A, 5d87:A
25 1d6s:A 322 317 0.2446 0.3851 0.3912 2.36e-49 1d6s:B, 1fcj:A, 1fcj:B, 1fcj:C, 1fcj:D, 1oas:A, 1oas:B, 6z4n:AAA, 6z4n:BBB
26 6kr5:B 336 319 0.2229 0.3363 0.3542 9.38e-49 6kr5:A
27 3t4p:A 319 317 0.2249 0.3574 0.3596 6.49e-48 3tbh:A
28 8b9w:A 329 317 0.2268 0.3495 0.3628 1.98e-47 8b9w:B
29 6xo2:A 294 314 0.2110 0.3639 0.3408 5.09e-46 7mfj:AAA, 6pmu:A, 6pmu:B
30 8b9y:C 330 317 0.2229 0.3424 0.3565 1.47e-41 8b9y:A, 8b9y:B, 8b9y:D
31 5dbh:X 312 316 0.2327 0.3782 0.3734 7.33e-41 6aif:A, 5dbe:X, 7djq:A, 3iqg:X, 3iqh:X, 3iqi:X, 4li3:X, 4nu8:X, 4ore:X, 1y7l:A, 7yod:A, 7yoh:A, 7yoi:A, 7yol:A, 7yom:A, 4zu1:X, 4zu6:X
32 4air:A 304 317 0.2091 0.3487 0.3344 1.66e-39 4air:B
33 3dwg:A 325 280 0.1854 0.2892 0.3357 1.37e-36 3dwg:B, 3dwi:A, 3dwi:B, 5i6d:B, 5i6d:C, 5i6d:D, 5i7a:B, 5i7a:C, 5i7a:D, 5i7h:B, 5i7h:C, 5i7h:D, 5i7o:B, 5i7o:C, 5i7o:D, 5i7r:B, 5i7r:A, 5iw8:A, 5iw8:B
34 5iwc:A 297 219 0.1716 0.2929 0.3973 1.99e-34 5i6d:A, 5i7a:A, 5i7h:A, 5i7o:A, 5iwc:B
35 5z5c:B 336 328 0.1972 0.2976 0.3049 7.97e-29 5b53:A, 5b55:A, 5b55:B, 5z5c:A, 5z5c:C, 5z5c:D
36 8if7:A 342 333 0.1795 0.2661 0.2733 3.26e-19
37 8y1j:A 502 144 0.0986 0.0996 0.3472 2.86e-13 8y1j:B
38 7nbc:AAA 323 276 0.1479 0.2322 0.2717 2.80e-12 3hmk:A, 3hmk:B, 3l6b:A, 3l6c:A, 3l6c:B, 3l6r:A, 7nbc:BBB, 7nbc:CCC, 7nbc:DDD, 7nbd:AAA, 7nbd:BBB, 7nbd:DDD, 7nbd:CCC, 7nbf:AAA, 7nbf:CCC, 7nbf:BBB, 7nbf:DDD, 7nbg:AAA, 7nbg:BBB, 7nbg:CCC, 7nbg:DDD, 7nbh:AAA, 7nbh:BBB, 7nbh:CCC, 7nbh:DDD, 6slh:AAA, 6slh:BBB, 6slh:CCC, 6slh:DDD, 5x2l:A, 5x2l:B, 6zsp:AAA, 6zsp:BBB, 6zuj:AAA, 6zuj:BBB, 6zuj:CCC, 6zuj:DDD
39 6nmx:A 350 306 0.1578 0.2286 0.2614 1.46e-10 6cgq:A, 6cgq:B, 6nmx:B, 6nmx:C, 6nmx:D
40 5b36:B 383 313 0.1637 0.2167 0.2652 7.79e-10 5b36:A, 5b3a:A, 5b3a:B, 6l0p:A, 6l0p:B, 6l0p:C, 6l0p:D, 6l0q:A, 6l0q:B, 6l0q:C, 6l0q:D, 6l0r:A, 6l0r:B, 6l0r:C, 6l0r:D, 6l0s:A, 6l0s:B, 6l0s:C, 6l0s:D, 3vsa:A, 3vsa:B, 3vsc:A, 3vsc:B, 3vsd:A, 3vsd:B, 1wkv:A, 1wkv:B
41 5cvc:A 329 199 0.1124 0.1733 0.2864 1.54e-08 5cvc:B, 5cvc:C
42 8h4q:N 488 216 0.1065 0.1107 0.2500 1.11e-06 8h4h:N, 8h4h:A, 8h4q:A
43 2d1f:A 349 290 0.1341 0.1948 0.2345 7.70e-06 2d1f:B
44 2zpu:A 319 319 0.1637 0.2602 0.2602 8.56e-06 1v71:A, 1wtc:A, 2zr8:A
45 1tdj:A 494 151 0.0907 0.0931 0.3046 9.70e-05
46 4d9n:A 391 148 0.0750 0.0972 0.2568 6.44e-04 4d9m:A, 4d9m:B, 4d9n:B
47 4d9k:A 366 54 0.0434 0.0601 0.4074 7.10e-04 4d9k:B, 4d9k:C
48 1m6y:A 293 54 0.0454 0.0785 0.4259 0.002 1m6y:B, 1n2x:A, 1n2x:B
49 2zsj:A 350 293 0.1400 0.2029 0.2423 0.018 2zsj:B, 2zsj:C, 2zsj:D
50 3aex:A 351 311 0.1519 0.2194 0.2476 0.048 3aex:B, 3aey:A, 3aey:B, 1uim:A, 1uim:B, 1uin:A, 1uin:B, 1v7c:A, 1v7c:B, 1v7c:C, 1v7c:D
51 1ve5:A 308 148 0.0947 0.1558 0.3243 0.057 1ve5:B
52 5ey5:B 383 339 0.1617 0.2141 0.2419 0.066 5ey5:D
53 8jpo:A 733 58 0.0316 0.0218 0.2759 0.098 8jpo:B, 8jpr:A, 8jpr:B
54 8vhh:A 389 113 0.0611 0.0797 0.2743 0.13 8egy:A, 8egy:B, 8egz:A, 8egz:B, 8eh0:A, 8eh0:B, 8eh1:A, 8eh1:B, 8vhh:B
55 1rqx:C 338 296 0.1381 0.2071 0.2365 0.14 1rqx:A, 1rqx:B, 1rqx:D, 1tyz:A, 1tyz:B, 1tyz:C, 1tyz:D, 1tz2:A, 1tz2:B, 1tz2:C, 1tz2:D, 1tzj:A, 1tzj:B, 1tzj:C, 1tzj:D, 1tzk:A, 1tzk:B, 1tzk:C, 1tzk:D, 1tzm:A, 1tzm:B, 1tzm:C, 1tzm:D
56 4gqy:A 147 56 0.0355 0.1224 0.3214 0.19 4gqy:B, 4gqy:C, 4gqy:D
57 5ygr:D 388 158 0.0868 0.1134 0.2785 0.21 5ygr:A, 5ygr:C
58 5ygr:B 365 53 0.0355 0.0493 0.3396 0.31
59 3ddj:A 279 62 0.0316 0.0573 0.2581 0.34
60 4d8u:H 331 50 0.0375 0.0574 0.3800 1.2 4d8u:A, 4d8u:B, 4d8u:C, 4d8u:D, 4d8u:E, 4d8u:F, 4d8u:G, 4d8w:A, 4d8w:C, 4d8w:D, 4d92:A, 4d92:B, 4d92:C, 4d92:D, 4d96:A, 4d96:B, 4d96:C, 4d96:D, 4d97:A, 4d97:B, 4d97:C, 4d97:D, 4d99:A, 4d99:B, 4d99:C, 4d99:D, 4d9b:A, 4d9b:B, 4d9b:C, 4d9b:D, 4d9c:A, 4d9c:B, 4d9c:C, 4d9c:D, 4d9e:A, 4d9e:B, 4d9e:C, 4d9e:D, 4d9f:A, 4d9f:B, 4d9f:C, 4d9f:D
61 1td2:A 287 106 0.0611 0.1080 0.2925 1.5 1td2:B
62 1hwm:B 264 49 0.0394 0.0758 0.4082 1.6 1hwn:B, 1hwo:B, 1hwp:B
63 3l31:A 234 58 0.0276 0.0598 0.2414 1.8 3l2b:A, 3l2b:B, 3l31:B
64 4fxs:A 467 67 0.0375 0.0407 0.2836 2.1
65 8jjn:C 326 122 0.0671 0.1043 0.2787 2.1 8jjn:A, 8jjn:B, 8jjq:C, 8jjq:A, 8jjq:B, 8jjt:C, 8jjt:A, 8jjt:B, 8rz3:A, 8rz3:B, 8rz3:C
66 3kpc:A 124 59 0.0296 0.1210 0.2542 2.2 3kpb:A, 3kpb:C, 3kpb:D, 3kpd:A, 3kpd:B, 3kpd:C, 3kpd:D
67 2yvx:A 442 128 0.0671 0.0769 0.2656 2.8 8h5e:A, 4u9n:B, 4wib:B, 5x9g:A, 5x9g:B, 5x9g:C, 5x9g:D, 5x9h:A, 5x9h:B, 2yvx:B, 2yvx:C, 2yvx:D, 2yvy:A, 2zy9:A, 2zy9:B
68 4hu0:A 330 124 0.0513 0.0788 0.2097 3.3
69 7aor:ax 161 33 0.0197 0.0621 0.3030 3.9 6hiv:DW, 6hiw:DW, 6hiz:DW, 7pua:DW, 7pub:DW, 6sg9:DW, 6sgb:DW
70 3bwe:A 188 89 0.0572 0.1543 0.3258 4.3 6af5:A, 6af9:A, 6afa:A, 6afb:A, 6afc:A, 6afd:A, 6afe:A, 6aff:A, 6afg:A, 6afh:A, 6afi:A, 6afj:A, 6afl:A, 3bwe:C, 3bwe:D, 3bwe:E, 3bwe:F, 4mnt:A, 4n0m:A, 4p35:A, 4p36:A, 7pa2:AAA, 7pa3:AAA, 8ppw:A, 8pq0:A
71 7pnt:4 589 31 0.0276 0.0238 0.4516 4.4 7pnu:4, 7pnv:4, 7pnw:4
72 1j0a:A 325 162 0.0750 0.1169 0.2346 5.0 1j0a:B, 1j0a:C, 1j0b:A, 1j0b:B, 1j0b:C, 1j0b:D, 1j0b:E, 1j0b:F, 1j0b:G, 1j0b:H, 1j0b:I, 1j0b:J, 1j0b:K, 1j0b:L, 1j0b:M, 1j0b:N, 1j0b:O, 1j0b:P, 1j0b:Q, 1j0b:R, 1j0b:S, 1j0b:T, 1j0b:U, 1j0b:V, 1j0b:W, 1j0b:X
73 7pji:A 445 39 0.0316 0.0360 0.4103 5.0 4dqw:A, 4dqw:B, 6gk9:A, 6gk9:D, 7pji:B
74 7ok0:D 261 56 0.0335 0.0651 0.3036 5.0 7oq4:D, 7oqy:D
75 5ks7:A 123 88 0.0414 0.1707 0.2386 5.1 5ks7:B
76 7qem:B 428 39 0.0316 0.0374 0.4103 5.1 7qdx:A, 7qdx:B, 7qem:A, 7qem:D
77 1f2d:A 341 287 0.1203 0.1789 0.2125 5.2 1f2d:B, 1f2d:C, 1f2d:D, 1j0c:A, 1j0c:B, 1j0c:C, 1j0c:D, 1j0d:A, 1j0d:B, 1j0d:C, 1j0d:D, 1j0e:A, 1j0e:B, 1j0e:C, 1j0e:D
78 2af6:G 246 47 0.0237 0.0488 0.2553 5.5 2af6:A, 2af6:B, 2af6:D, 2af6:C, 2af6:E, 2af6:F, 2af6:H, 2gq2:A, 2gq2:C, 2gq2:D, 2gq2:B, 3gwc:A, 3gwc:B, 3gwc:D, 3gwc:C, 3gwc:E, 3gwc:F, 3gwc:H, 3gwc:G, 3hzg:A, 3hzg:B, 3hzg:D, 3hzg:C
79 2b25:A 254 25 0.0237 0.0472 0.4800 5.7 2b25:B
80 8qqv:A 356 48 0.0355 0.0506 0.3750 6.2 8qqv:B, 8qqv:D, 8qqv:C, 8qqv:E, 8qqv:F, 8qqv:G, 8qqv:H, 8qqx:A, 8qqx:B, 8qqx:C, 8qqx:D, 8qqx:E, 8qqx:F, 8qqx:G, 8qqx:H
81 3lhh:A 125 34 0.0276 0.1120 0.4118 7.7
82 5xj2:A 454 72 0.0375 0.0419 0.2639 8.3 5xj2:B, 5xj2:C, 5xj2:D, 5zq0:A, 5zq1:A, 5zq8:B, 5zq8:A, 5zth:A
83 6hiv:DD 791 69 0.0335 0.0215 0.2464 9.8 6hiw:DD, 6hiy:DD, 7pua:DD, 7pub:DD, 6sga:DD, 6sgb:DD
84 8jmr:B 167 45 0.0335 0.1018 0.3778 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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