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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LVAGPAALRFAAAASWQVVRGRCVEHFPRVLEFLRSLRAVAPGLVRYRHHERLCMGLKAKVVVELILQGRPWAQVLKALN
HHFPESGRDPKATKQDLRKILEAQETFYQQVKQLSEAPVDLASKLQELEQEYGEPFLAAMEKLLFEYLCQLEKALPTPQA
QQLQDVLSWMQPGVSITSSLAWRQYGVDMGWL

The query sequence (length=192) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5xyf:A 192 192 1.0000 1.0000 1.0000 1.16e-140
2 7dkb:A 697 60 0.0938 0.0258 0.3000 1.9 7dkb:B, 7dkc:A, 7dkc:B, 7dkd:A, 7dkd:B, 7dke:A, 7dke:B, 8grt:A, 8grt:B
3 7pab:A 415 75 0.1146 0.0530 0.2933 2.0 7pab:C
4 3m83:A 325 70 0.0990 0.0585 0.2714 2.7 5jib:A, 5jib:B, 5jib:C, 5jib:D, 5jib:E, 5jib:F, 3m81:A, 3m81:C, 3m81:B, 3m81:D, 3m81:E, 3m81:F, 3m82:A, 3m82:C, 3m82:B, 3m82:D, 3m82:E, 3m82:F, 3m83:B, 3m83:C, 3m83:D, 3m83:E, 3m83:F
5 6sup:A 2128 44 0.0677 0.0061 0.2955 3.6
6 6g0c:A 624 65 0.0990 0.0304 0.2923 4.2
7 3x27:D 314 18 0.0365 0.0223 0.3889 4.5 3x27:A, 3x27:B, 3x27:C
8 8wbd:B 330 52 0.0729 0.0424 0.2692 4.8 8wbd:C
9 8wbd:b 352 52 0.0729 0.0398 0.2692 5.1
10 5yij:A 959 65 0.0990 0.0198 0.2923 5.2 5ysi:A
11 3n75:A 711 58 0.0833 0.0225 0.2759 5.6 3n75:D, 3n75:B, 3n75:E, 3n75:C, 6q7l:A, 6q7l:F, 6q7l:B, 6q7l:C, 6q7l:D, 6q7l:J, 6q7l:E, 6q7l:H, 6q7l:G, 6q7l:I, 6q7l:K, 6q7l:R, 6q7l:L, 6q7l:Q, 6q7l:M, 6q7l:P, 6q7l:N, 6q7l:T, 6q7l:O, 6q7l:S, 6q7m:A, 6q7m:F, 6q7m:B, 6q7m:C, 6q7m:D, 6q7m:J, 6q7m:E, 6q7m:H, 6q7m:G, 6q7m:I, 6q7m:K, 6q7m:R, 6q7m:L, 6q7m:Q, 6q7m:M, 6q7m:P, 6q7m:N, 6q7m:O, 6q7m:S, 6q7m:T
12 1ef9:A 261 57 0.0833 0.0613 0.2807 5.6 6n92:A, 6n92:B, 6n92:C, 6n92:D, 6n92:E, 6n92:F, 6n93:A, 6n93:B, 6n93:C, 6n93:D, 6n93:E, 6n93:F, 6n94:A, 6n94:B, 6n94:C, 6n94:D, 6n94:E, 6n94:F, 6n95:A, 6n95:B, 6n95:C, 6n95:D, 6n95:E, 6n95:F, 6n96:A, 6n96:B, 6n96:C, 6n96:D, 6n96:E, 6n96:F, 6n97:A, 6n97:B, 6n97:C, 6n97:D, 6n97:E, 6n97:F
13 7lsy:Y 855 56 0.0990 0.0222 0.3393 7.5 6bkg:A, 4htp:A, 4htp:B, 3w1b:A, 3w1g:A, 3w5o:A, 3w5o:B
14 6gfu:A 386 67 0.0885 0.0440 0.2537 8.4 5w76:A, 5w7q:A
15 6e10:1 719 61 0.0833 0.0223 0.2623 9.8 6e10:2, 6e10:3, 6e10:4, 6e10:5, 6e10:6, 6e11:1, 6e11:3, 6e11:2, 6e11:4, 6e11:5, 6e11:6
16 3woj:A 698 60 0.0885 0.0244 0.2833 9.9 3woi:B, 3woj:B, 3wol:A, 3wol:B, 3wom:A, 3wom:B, 3won:A, 3won:B, 3woo:A, 3woo:B, 3wop:A, 3wop:B, 3woq:A, 3woq:B, 3wor:A, 3wor:B, 4y06:A, 4y06:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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