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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LSTSLSALPAAARDFVEEAVRLCRPREVLLCDGSEEEGKELLRGLQDDGVLHPLPKYDNCWLARTDPRDVARVESKTVLV
TPEQSDAVPPPPPSGGPPQLGNWMSPNAFQAAVQERFPGCMAGRPLYVIPFSMGPPTSPLAKLGVQVTDSPYVVLSMRIM
TRVGPAVLQRLDDDFVRCLHSVGRPLPLTEPLVSSWPCDPSRVLVAHIPSERRIVSFGSGYGGNSLLGKKCFALRIASRM
AQQQGWLAEHMLILGVTSPSGEKRYMAAAFPSACGKTNLAMMTPSLPGWRIHCVGDDIAWMKFDDEGRLRAINPERGFFG
VAPGTSSRTNPNAMATIARNTIFTNVGLRSDGGVYWDGLDEPTEPGVTYTSWLGKPWKHGDPEPCAHPNSRFCAPADQCP
IMDPRWDDPEGVPIDAIIFGGRRPRGVPLVVEAFGWRHGVFMGSAMRSEATAAAEHKGGRLMHDPFAMRPFFGYNAGRYL
EHWLSTGLRSNARLPRLFHVNWFLRDNEGRFVWPGFGHNARVLAWIFGRIQGRDTARPTPIGWVPKEGDLDLGGLPGVDY
SQLFPMEKGFWEEECRQLREYYGENFGADLPRDVMAELEGLEERVRKM

The query sequence (length=608) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2fah:C 608 608 1.0000 1.0000 1.0000 0.0 2faf:A, 2faf:B, 2fah:D, 2fah:A, 2fah:B, 2qzy:A, 2qzy:B
2 3dt7:A 624 609 0.6497 0.6330 0.6486 0.0 3dt2:A, 3dt4:A, 3dt4:C, 3dt7:B, 3dtb:A, 3dtb:B, 5fh0:A, 5fh1:A, 5fh2:A, 5fh3:A, 5fh4:A, 5fh5:A, 2gmv:A, 2gmv:B, 4gmm:A, 4gmu:A, 4gmw:A, 4gmz:A, 4gnl:A, 4gnm:A, 4gno:A, 4gnp:A, 4gnq:A, 1khb:A, 1khe:A, 1khf:A, 1khg:A, 7l36:A, 7l3m:A, 7l3v:A, 1m51:A, 3moe:A, 3mof:A, 3mof:B, 3moh:A, 3moh:B, 1nhx:A, 4ox2:A, 4ox2:B, 6p5o:A, 2qew:A, 2qey:A, 2qf1:A, 2qf2:A, 2qf2:B, 2rk7:A, 2rk7:B, 2rk8:A, 2rk8:B, 2rka:A, 2rka:C, 2rkd:A, 2rke:A, 5v97:A, 5v9f:A, 5v9g:A, 5v9h:A, 5v9h:B, 4yw8:A, 4yw9:A, 4ywb:A, 4ywb:C, 4ywd:A
3 5v95:A 592 609 0.6283 0.6453 0.6273 0.0
4 4r43:A 601 600 0.4885 0.4942 0.4950 0.0 5i67:A, 4rcg:A, 4wie:A, 4wiu:A, 4wl8:A, 4wou:A, 4wpt:A, 4wpu:A, 4wpv:A
5 1os1:A 537 171 0.0773 0.0875 0.2749 0.17 1aq2:A, 6asi:A, 6asm:A, 6asn:A, 6at2:A, 6at3:A, 6at3:B, 6at4:A, 6at4:B, 1ayl:A, 6com:A, 6crt:A, 1k3c:A, 1k3d:A, 2olq:A, 2olr:A, 2pxz:X, 2py7:X, 6v2l:A, 6v2m:A, 6v2n:A
6 6xmt:A 1092 77 0.0411 0.0229 0.3247 1.2 6xmq:A, 6xms:A, 6xmu:A
7 6fm3:A 304 46 0.0263 0.0526 0.3478 2.4 6fm0:A, 6fm0:B
8 8cem:B 974 75 0.0345 0.0216 0.2800 5.1
9 1ylh:A 524 99 0.0461 0.0534 0.2828 7.0
10 8b0i:D 282 20 0.0148 0.0319 0.4500 9.2 8b0i:A, 8b0i:B, 8b0j:A, 8b0j:B, 8b0j:D, 8b0j:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218