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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESK
EKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDP
LVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVIT
YLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPS
SSKTRQIISTIRTQ

The query sequence (length=334) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3asx:A 335 334 0.9880 0.9851 0.9880 0.0 1ezf:A, 1ezf:B, 1ezf:C, 3lee:A, 3lee:B, 3lee:C, 3lee:D, 3lee:E, 3q2z:A, 3q30:A, 3v66:A, 3vj9:A, 3vjc:A, 3vjc:B, 3vjc:C, 3vjc:D, 3vjc:E, 3vjc:F, 3wc9:A, 3wc9:B, 3wc9:C, 3wc9:D, 3wc9:E, 3wc9:F, 3wcd:A, 3wcd:B, 3wcd:D, 3wcd:E, 3wcf:A, 3wcf:B, 3wcf:C, 3wcf:D, 3wcf:E, 3wcf:F, 3wch:A, 3wch:B, 3wch:C, 3wch:D, 3wch:E, 3wch:F, 3wci:A, 3wci:B, 3wci:C, 3wci:D, 3wci:E, 3wci:F, 3wcj:A, 3wcj:B, 3wcj:C, 3wcj:D, 3wcj:E, 3wcj:F, 3wcl:A, 3wcm:A, 3wcm:B, 3wcm:C, 3wcm:D, 3wcm:E, 3wcm:F, 3wef:A, 3wef:B, 3wef:C, 3wef:D, 3wef:E, 3weg:A, 3weh:A, 3wei:A, 3wej:A, 3wek:A, 3wsa:A, 3wsa:B, 3wsa:C, 3wsa:E, 8wtq:A, 8wtr:A
2 3lee:F 262 332 0.7784 0.9924 0.7831 0.0
3 7wgh:A 350 339 0.4491 0.4286 0.4425 1.81e-97 7wgi:A
4 3wcc:C 342 328 0.4251 0.4152 0.4329 3.37e-90 3wca:A, 3wca:B, 3wca:C, 3wca:D, 3wcb:A, 3wcb:B, 3wcb:D, 3wcc:A, 3wcc:B, 3wcc:D, 3wce:A, 3wce:B, 3wce:C, 3wce:D, 3wcg:A, 3wcg:B, 3wcg:C, 3wcg:D, 3wsb:A, 3wsb:B, 3wsb:C, 3wsb:D
5 3acw:A 284 217 0.1557 0.1831 0.2396 6.53e-07 3acx:A, 3acy:A, 3adz:A, 3ae0:A, 3ae0:B, 4e9u:A, 4e9z:A, 4ea0:A, 4ea0:B, 4ea1:A, 4ea2:A, 4f6v:A, 4f6x:A, 3lgz:B, 3npr:A, 3nri:A, 3tfn:A, 3tfp:A, 3tfv:A, 3vje:A, 3vje:B, 3w7f:A, 3w7f:B, 2zcq:A, 2zcr:A, 2zcs:A, 2zy1:A
6 5iys:A 283 201 0.1527 0.1802 0.2537 1.07e-05
7 8is7:A 275 248 0.1527 0.1855 0.2056 1.19e-04 8is8:A, 8is9:A, 8isa:A
8 3pr8:A 218 29 0.0329 0.0505 0.3793 0.38 3pr8:B, 3pr8:C, 3pr8:D
9 5x20:A 312 94 0.0778 0.0833 0.2766 0.59 3wfj:A, 3wfj:B, 3wfj:C, 3wfj:D, 3wfj:E, 3wfj:G, 5x20:B, 5x20:C, 5x20:D, 5x20:E
10 8i9w:CP 356 46 0.0479 0.0449 0.3478 2.0 8i9r:CP, 8i9t:CP, 8i9v:CP, 8i9x:CP, 8i9y:CP, 8i9z:CP, 8ia0:CP
11 7mvv:A 1542 103 0.0689 0.0149 0.2233 3.9 4knh:B, 7tbi:I1, 7tbi:I2, 7tbj:I1, 7tbj:I2, 7tbj:I3, 7tbj:I4, 7tbj:I5, 7tbk:I1, 7tbk:I2, 7tbk:I3, 7tbk:I4, 7tbk:I5, 7tbl:I1, 7tbl:I2, 7tbl:I3, 7tbl:I4, 7tbl:I5, 7tbm:I1, 7tbm:I2, 7tbm:I3, 7tbm:I4, 7tbm:I5
12 6j7k:A 385 42 0.0419 0.0364 0.3333 4.8 6j7l:A, 6j7m:A, 6j7m:C
13 3wfj:F 263 48 0.0449 0.0570 0.3125 6.5 3wfj:H
14 2a6o:A 152 34 0.0359 0.0789 0.3529 6.6 2a6o:B, 6fi8:A, 6fi8:B, 6fi8:G, 6fi8:H, 2vhg:A, 2vhg:B, 2vic:A, 2vic:B, 2vih:A, 2vih:B, 2vju:A, 2vju:B, 2vjv:A, 2vjv:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218