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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LSSEQQRAFLAVTQTPHPAHLITGPAGTGKTTLLYALQEFYKGRAVTLAPTGTAALQARGQTVHSFFRFPARLLRYRHPE
DIRPPGPHSPLRKAIEQMEVLILDEVGMVRVDLLEAMDWALRKTRKRLEEPFGGVKVLLLGDTRQLEPVVPGGEEALYIA
RTWGGPFFFQAHVWEEVALRVHRLWESQRQREDPLFAELLKRLRQGDPQALETLNRAAVRPDGGEEPGTLILTPRRKEAD
ALNLKRLEALPGKPLEYQAQVKGEFAETDFPTEAALTLKKGAQVILLRNDPLGEYFNGDLGWVEDLEAEALAVRLKRNGR
RVVIRPFVWEKIVYTYDSEREEIKPQVVGTFRQVPVRLAWALTVHKAQGLTLDKVHLELGRGLFAHGQLYVALTRVRRLQ
DLSLSRPIAPTELLWRPEVEVFETRIQEGIWQKS

The query sequence (length=434) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7oar:A 442 434 0.9977 0.9796 0.9977 0.0 7bil:A, 7bil:B, 6s3h:A, 6s3h:B, 6s3i:A, 6s3m:A, 6s3m:B, 6s3n:A, 6s3n:B, 6s3o:A, 6s3p:A
2 7oar:B 413 434 0.9447 0.9927 0.9447 0.0
3 8bns:A 433 435 0.3710 0.3718 0.3701 7.91e-93 8bns:B, 8bns:C, 8bns:D
4 8bnx:A 422 430 0.3364 0.3460 0.3395 4.30e-80 8bnv:A
5 5ftc:A 431 409 0.3157 0.3179 0.3350 3.61e-63 5fhd:A, 5fhe:A, 5fhf:A, 5ftb:A, 5fte:A, 5ftf:A, 6l3g:A, 6l3g:B
6 5fhd:B 400 409 0.2949 0.3200 0.3130 4.81e-48
7 6hph:A 418 416 0.3018 0.3134 0.3149 3.95e-37 9fb8:A, 5fhh:A, 5fhh:B, 6hpq:A, 6hpq:B, 6hpu:A, 6hpu:B
8 7otj:A 438 443 0.3157 0.3128 0.3093 6.37e-35 7otj:B
9 7lcc:A 1369 474 0.3041 0.0964 0.2785 6.15e-30
10 8xak:C 490 320 0.2189 0.1939 0.2969 1.08e-22
11 8xak:C 490 90 0.0899 0.0796 0.4333 6.01e-07
12 5o6b:A 528 320 0.2189 0.1799 0.2969 2.65e-22 5o6b:B, 5o6d:A, 5o6d:B, 5o6e:A, 5o6e:B, 8xak:A
13 5o6b:A 528 90 0.0899 0.0739 0.4333 5.36e-07 5o6b:B, 5o6d:A, 5o6d:B, 5o6e:A, 5o6e:B, 8xak:A
14 3gp8:A 551 407 0.2442 0.1924 0.2604 5.45e-06 3gpl:A, 3gpl:B
15 2xzl:A 756 59 0.0553 0.0317 0.4068 0.002
16 8gme:C 439 189 0.1198 0.1185 0.2751 0.007 8s9i:A, 3upu:A, 3upu:B, 3upu:C
17 5d4w:A 688 35 0.0415 0.0262 0.5143 0.11 5d4w:B, 5d4w:C, 5zui:A
18 8dr0:D 344 140 0.0783 0.0988 0.2429 0.12 8dqw:D, 8dqx:D, 8dqz:D, 8dr1:D, 8dr3:D, 8dr4:D, 8dr5:D, 8dr6:D, 8dr7:D, 8fs3:D, 8fs4:D, 8fs5:D, 8fs6:D, 8fs7:D, 8fs8:D, 7sgz:D, 7sh2:D, 7st9:D, 7stb:D, 7ste:D, 1sxj:D, 7tfh:D, 7tfi:D, 7tfj:D, 7tfk:D, 7tfl:D, 7thj:D, 7thv:D, 8thb:D, 8thc:D, 8thd:D, 7ti8:D, 7tib:D, 7tic:D, 7tid:D, 7tku:D, 8tw7:2, 8tw8:2, 8twa:2, 8twb:2, 7u19:D, 7u1a:D, 7u1p:D
19 4pht:B 442 33 0.0392 0.0385 0.5152 0.12 1p9r:A, 1p9w:A, 4pht:A, 4pht:C
20 5ld2:D 605 142 0.0899 0.0645 0.2746 0.15 8b1t:D, 8b1u:D, 7mr3:D, 6sjb:D, 6sje:D, 6sjf:D, 6sjg:D, 6t2u:D, 6t2v:D
21 8gme:D 406 175 0.1083 0.1158 0.2686 0.18
22 8rd8:A4 233 85 0.0622 0.1159 0.3176 0.53 8rdv:A4, 8rdw:A4
23 8jx6:B 451 160 0.0945 0.0909 0.2562 0.66
24 4zgn:A 279 79 0.0507 0.0789 0.2785 1.2 4zgp:A
25 8xoo:O 572 70 0.0507 0.0385 0.3143 1.6
26 3jvv:C 337 35 0.0300 0.0386 0.3714 1.7 3jvv:A, 3jvv:B
27 8xon:O 593 70 0.0507 0.0371 0.3143 1.8 8xon:S, 8xon:R, 8xon:Q, 8xon:P, 8xon:T, 8xoo:R, 8xoo:Q, 8xoo:P, 8xoo:T, 8xoo:S
28 2wjy:A 773 61 0.0530 0.0298 0.3770 1.8 2gjk:A, 2gk6:A, 2gk6:B, 2gk7:A, 8rxb:E, 8rxb:A, 8rxb:D, 8rxb:I, 8rxb:L, 8rxb:P, 2wjv:A, 2wjv:B, 2xzo:A
29 8gzg:Z 1175 62 0.0461 0.0170 0.3226 2.0
30 5n8o:A 1432 159 0.0945 0.0286 0.2579 2.1 4l0j:A, 1p4d:A, 1p4d:B, 1p4d:C, 2q7t:A, 2q7t:B, 2q7u:A
31 8gzh:Z 1217 62 0.0461 0.0164 0.3226 2.1
32 2drk:A 59 47 0.0415 0.3051 0.3830 2.1 2drm:A, 2drm:B, 2drm:C, 2drm:D
33 5e7p:A 719 37 0.0323 0.0195 0.3784 2.3 5e7p:B
34 8a8h:B 146 18 0.0253 0.0753 0.6111 2.4
35 7zhf:A 250 27 0.0300 0.0520 0.4815 2.7 7zhk:A, 7zhk:B, 7zhk:C
36 5svc:A 763 54 0.0461 0.0262 0.3704 2.9 5m45:A, 5m45:D, 5m45:G, 5m45:J, 5svb:A, 5svb:D, 5svc:D
37 7m4u:b 225 123 0.0760 0.1467 0.2683 2.9 7m4w:b, 7m4x:b, 7m4y:b, 7m4z:b, 7ryf:b, 7ryg:b, 7ryh:b, 7uvv:b, 7uvw:b, 7uvx:b, 7uvy:b, 7uvz:b, 7uw1:b, 6v39:b, 6v3a:b, 6v3b:b, 6v3e:b, 6yt9:c
38 2owb:A 294 47 0.0323 0.0476 0.2979 3.0 4a4l:A, 4a4o:A, 8bjt:A, 3fc2:A, 4j52:A, 4j53:A, 3kb7:A, 2ou7:A, 2rku:A, 5ta6:A, 5ta8:A, 3thb:A, 8x72:A, 2yac:A
39 1moz:A 178 31 0.0392 0.0955 0.5484 3.0 8ezj:C, 8ezj:D, 1moz:B
40 1gm5:A 729 76 0.0530 0.0316 0.3026 3.7
41 6qs4:C 630 36 0.0369 0.0254 0.4444 3.9 5og1:C, 5og1:D, 6qs4:D, 6qs4:E, 6qs6:C, 6qs6:D, 6qs7:C, 6qs7:D, 6qs7:E, 6qs8:C, 6qs8:D, 6qs8:E
42 3k70:D 547 62 0.0484 0.0384 0.3387 3.9 3k70:G, 1w36:G
43 7ow8:A 577 41 0.0392 0.0295 0.4146 3.9 7bg4:A, 7bg4:B, 7ow8:B, 6r72:A, 6r72:B, 6r72:C, 6r72:D, 6r81:A, 6r81:B
44 1upt:G 170 31 0.0392 0.1000 0.5484 4.1 4dcn:A, 4dcn:B, 5ee5:B, 5j5c:A, 1r4a:A, 1r4a:B, 1r4a:C, 1r4a:D, 1upt:A, 1upt:C, 1upt:E
45 6oay:F 558 36 0.0369 0.0287 0.4444 4.1 6og2:F
46 6rn4:F 680 34 0.0369 0.0235 0.4706 4.2 6rn3:F, 6rn4:A
47 6qs4:B 582 36 0.0369 0.0275 0.4444 4.2 6oax:C, 6oax:E, 6oax:D, 6oax:B, 6oax:A, 6oax:F, 6oay:C, 6oay:E, 6oay:D, 6oay:B, 6oay:A, 5og1:B, 6og1:F, 6og1:A, 6og2:A, 6qs4:A, 6qs4:F, 6qs6:A, 6qs6:B, 6qs6:E, 6qs6:F, 6qs7:A, 6qs7:B, 6qs7:F, 6qs8:A, 6qs8:B, 6qs8:F
48 5og1:A 819 34 0.0369 0.0195 0.4706 4.7 5ofo:C, 5ofo:F, 5ofo:E, 5ofo:D, 5ofo:B, 5ofo:A, 5og1:E, 6rn2:A, 6rn2:B, 6rn2:C, 6rn2:D, 6rn2:F, 6rn2:E, 6rn3:A, 6rn3:B, 6rn3:C, 6rn3:D, 6rn3:E, 6rn4:B, 6rn4:C, 6rn4:D, 6rn4:E
49 4ciu:A 657 34 0.0369 0.0244 0.4706 4.8
50 5eg1:B 576 22 0.0230 0.0174 0.4545 4.9 5eg1:A, 5ofr:A, 5ofr:B, 4pl0:A, 4pl0:B, 8px9:A, 8px9:B
51 2c03:B 297 152 0.0922 0.1347 0.2632 4.9 2c03:A, 2cnw:A, 2cnw:B, 2cnw:C, 2j7p:A, 2j7p:B, 1jpj:A, 1jpn:B, 1jpn:A, 1ls1:A, 1ng1:A, 2ng1:A, 1o87:A, 1o87:B, 1okk:A
52 3ggg:D 293 26 0.0276 0.0410 0.4615 5.0 2g5c:A, 2g5c:B, 2g5c:C, 2g5c:D, 3ggg:A, 3ggg:B, 3ggg:C, 3ggo:A, 3ggo:B, 3ggo:D, 3ggo:C, 3ggp:A, 3ggp:B, 3ggp:D, 3ggp:C
53 8umv:D 329 140 0.0806 0.1064 0.2500 5.4 8ui7:D, 8ui8:D, 8ui9:D, 8uii:D, 8umt:D, 8umw:D, 8umy:D, 8un0:D, 8unj:D, 6vvo:D, 7z6h:D
54 4b3g:A 614 81 0.0553 0.0391 0.2963 5.8 4b3g:B
55 8a8w:F 552 37 0.0346 0.0272 0.4054 6.4 8a8u:F, 8a8v:F
56 8a8w:D 577 37 0.0346 0.0260 0.4054 6.8 8a8u:B, 8a8u:C, 8a8u:D, 8a8u:E, 8a8u:A, 8a8v:B, 8a8v:C, 8a8v:D, 8a8v:E, 8a8v:A, 8a8w:A, 8a8w:B, 8a8w:C, 8a8w:E
57 7l6n:C 675 36 0.0323 0.0207 0.3889 7.5 7l6n:A, 7l6n:B, 6w6e:A
58 8ipr:A 504 22 0.0230 0.0198 0.4545 7.7 8ipr:D
59 5tsh:E 387 35 0.0369 0.0413 0.4571 7.7 5tsg:B, 5tsg:C, 5tsg:D, 5tsh:A, 5tsh:B, 5tsh:C, 5tsh:D, 5tsh:F, 5zfr:A, 5zfr:B, 5zfr:C
60 6w6h:C 636 36 0.0323 0.0220 0.3889 8.1 6w6e:B, 6w6e:C, 6w6g:A, 6w6g:B, 6w6g:C, 6w6h:A, 6w6h:B, 6w6h:F, 6w6i:A, 6w6i:B, 6w6i:C, 6w6j:A, 6w6j:B, 6w6j:C
61 7yse:D 643 84 0.0668 0.0451 0.3452 8.2 7yse:C
62 6w6i:F 605 36 0.0323 0.0231 0.3889 8.5 6w6j:F
63 2ax4:A 198 25 0.0253 0.0556 0.4400 8.6 2ax4:B, 2ax4:C, 2ax4:D, 8i1n:A, 8i1n:B, 8i1n:C, 8i1n:D, 8i1o:A, 8i1o:B, 8i1o:C, 8i1o:D
64 6djv:C 615 36 0.0323 0.0228 0.3889 8.8 6dju:A, 6dju:B, 6dju:C, 6djv:A, 6djv:B
65 1ex7:A 186 17 0.0253 0.0591 0.6471 8.8 1gky:A
66 6dju:F 531 36 0.0323 0.0264 0.3889 9.3 6w6g:F
67 3glf:G 378 212 0.1152 0.1323 0.2358 9.6 8giy:B, 8giy:C, 8giy:D, 8giz:B, 8giz:C, 8giz:D, 8gj0:B, 8gj0:C, 8gj0:D, 8gj1:B, 8gj1:C, 8gj1:D, 8gj2:B, 8gj2:C, 8gj2:D, 8gj3:B, 8gj3:C, 8gj3:D, 3glf:B, 3glf:C, 3glf:D, 3glf:H, 3glf:I, 3glg:B, 3glg:C, 3glg:D, 3glg:G, 3glg:H, 3glg:I, 3gli:B, 3gli:C, 3gli:D, 3gli:G, 3gli:H, 3gli:I, 1jr3:A, 1jr3:B, 1jr3:C, 1njf:A, 1njf:B, 1njf:C, 1njf:D, 1njg:A, 1njg:B, 8val:B, 8val:C, 8val:D, 8vam:B, 8vam:C, 8vam:D, 8vap:B, 8vap:C, 8vap:D, 8vaq:B, 8vaq:C, 8vaq:D, 8var:B, 8var:C, 8var:D, 8vas:B, 8vas:C, 8vas:D, 8vat:B, 8vat:C, 8vat:D, 1xxh:B, 1xxh:C, 1xxh:D, 1xxh:G, 1xxh:H, 1xxh:I, 1xxi:B, 1xxi:C, 1xxi:D, 1xxi:G, 1xxi:H, 1xxi:I

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218