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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LSLRPYEFWFVTGSQHLYGEEALKQVEEHSRIMVNEWNRDSVFPFPFVFKSVVTTPEEIRRVCLEANASEQCAGVVTWMH
TFSPAKMWIGGLLELRKPLLHLHTQFNRDIPWDSIDMDFMNLNQSAHGDREFGFMVTRLGMPRKVIVGHWQDAEVARRVR
GWAMTAVAAAVSRGLKVARFGDNMRQVAVTEGDKVEAEARFGWSVNGYGVGDLAERVRAVSEAEIDRLIDEYQSLYEFAP
GCEKGGPLHDGVREQARIELGLRSFLEEGGFEAFTTTFEDLHGMKQLPGLAVQRLMAEGYGFGGEGDWKTAALVRLMKVM
ADGKGTSFMEDYTYHFEPGNEMILGAHMLEVCPTIAATRPRIEVHPLSIGGKEDPARLVFDGGEGAAVNASLIDLGHRFR
LIVNEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSFAVTTEQLQDFAEMAGIECVVINEHTSVSS
FKNELKWNEVFWRGR

The query sequence (length=495) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7cyy:C 497 495 1.0000 0.9960 1.0000 0.0 7cx7:A, 7cx7:B, 7cx7:C, 7cx7:D, 7cx7:E, 7cx7:F, 7cyy:A, 7cyy:B, 7cyy:D, 7cyy:E, 7cyy:F
2 4r1q:E 496 495 0.8788 0.8770 0.8788 0.0 4r1p:A, 4r1p:B, 4r1p:C, 4r1p:D, 4r1p:E, 4r1p:F, 4r1q:A, 4r1q:D, 4r1q:B, 4r1q:F, 4r1q:C
3 7chl:A 498 498 0.7495 0.7450 0.7450 0.0 7chl:B, 7chl:C, 7chl:D, 7chl:E, 7chl:F, 7chl:G, 7chl:H, 7chl:I, 7chl:J, 7chl:K, 7chl:L, 7cxo:A, 7cxo:B, 7cxo:C, 7cxo:D, 7cxo:E, 7cxo:F
4 7ch3:B 495 494 0.5939 0.5939 0.5951 0.0 7ch3:C, 7ch3:D, 7ch3:E, 7ch3:I, 7ch3:F, 7ch3:G, 7ch3:H, 7ch3:J, 7ch3:K, 7ch3:L, 7cwv:A, 7cwv:B, 7cwv:C, 7cwv:D, 7cwv:E, 7cwv:F, 7cwv:G, 7cwv:H, 7cwv:I, 7cwv:J, 7cwv:K, 7cwv:L
5 4f2d:A 498 490 0.5778 0.5743 0.5837 0.0 4f2d:B, 4f2d:C, 2hxg:A, 2hxg:B, 2hxg:C
6 7ch3:A 469 494 0.5737 0.6055 0.5749 0.0
7 9cd7:A 276 62 0.0404 0.0725 0.3226 0.18 8udv:C
8 8ui7:C 339 51 0.0303 0.0442 0.2941 0.23 8ui8:C, 8ui9:C, 8uii:C, 8umt:C, 8umu:C, 8umv:C, 8umw:C, 8umy:C, 8un0:C, 8unj:C, 6vvo:C, 7z6h:G
9 7cqw:A 430 50 0.0364 0.0419 0.3600 1.4 7cqn:A, 7cqn:B, 7cqn:C, 7cqq:A, 7cqq:B, 7cqq:C, 7cqu:A, 7cqu:B, 7cqu:C, 7cqw:B, 7cqw:C, 7cqx:A, 7cqx:B, 7cqx:C
10 4ngu:A 317 79 0.0525 0.0820 0.3291 2.7
11 5i8d:A 335 31 0.0283 0.0418 0.4516 5.3 5tfk:A, 5ulu:A, 5un2:A
12 6pnx:B 294 47 0.0323 0.0544 0.3404 6.5 9cd7:B, 9cd7:C, 7dhl:A, 4k33:A, 6lvm:A, 6pnx:A, 8udt:A, 8udt:B, 8udt:C, 8udu:A, 8udu:B, 8udv:A, 8udv:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218