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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGAD
EPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTI
AARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSEYPVRRRQCEEVA
RALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQ
LVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL

The query sequence (length=385) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6q3x:A 393 389 1.0000 0.9796 0.9897 0.0 6gr2:A, 6gr2:B, 6gr2:C, 6gr2:D, 6gr2:E, 6gr2:F, 6gr2:G, 6gr2:H, 7ozx:A, 7ozx:B, 7ozx:C, 6q3w:A, 6q3w:B, 6q3w:C, 6q3x:B, 6q8z:A, 6q8z:B, 6q8z:C, 6q90:A, 6q90:B, 6q90:C, 6q90:D, 6q91:A, 6q91:B, 6q91:C, 6qje:A, 6qje:B, 6qje:C, 7rcl:A, 7rcl:B, 7rcl:C, 7rcl:D, 7rcm:A, 7rcm:B, 7s49:A, 7s49:B, 7s4c:A, 7s4c:B, 1wuu:A, 1wuu:B, 1wuu:C, 1wuu:D, 6zfh:A, 6zfh:B, 6zfh:C, 6zfh:D, 6zfh:E, 6zfh:F, 6zfh:G, 6zfh:H, 6zgv:A, 6zgv:B, 6zgv:E, 6zgv:D, 6zgw:A, 6zgw:B, 6zgw:E, 6zgw:D, 6zgx:A, 6zgx:B, 6zgx:D, 6zgx:E, 6zgy:A, 6zgy:B, 6zgy:E, 6zgz:A, 6zgz:B, 6zgz:E, 6zgz:D, 6zh0:A, 6zh0:B, 6zh0:E, 6zh0:D
2 6q91:D 360 382 0.9325 0.9972 0.9398 0.0 6qje:D
3 6teq:A 418 392 0.3662 0.3373 0.3597 7.24e-60 6tep:A, 6tep:D, 6tep:C, 6tep:B, 6teq:B, 6teq:C, 6teq:D, 6ter:A, 6ter:B, 6ter:C, 6ter:D
4 1s4e:F 351 368 0.3247 0.3561 0.3397 3.48e-58 1s4e:A, 1s4e:B, 1s4e:C, 1s4e:D, 1s4e:E, 1s4e:H, 1s4e:I
5 2dei:A 350 367 0.3169 0.3486 0.3324 3.24e-57 2dej:A
6 1pie:A 388 392 0.3610 0.3582 0.3546 2.82e-55
7 2a2d:A 448 448 0.3455 0.2969 0.2969 1.05e-40 2a2c:A
8 1s4e:G 255 194 0.1584 0.2392 0.3144 2.42e-20
9 1s4e:G 255 49 0.0597 0.0902 0.4694 2.05e-05
10 3v2u:C 516 234 0.1662 0.1240 0.2735 1.04e-18 3v2u:D
11 3v2u:C 516 93 0.0961 0.0717 0.3978 9.42e-12 3v2u:D
12 2aj4:A 509 245 0.1688 0.1277 0.2653 2.47e-17 2aj4:B
13 2aj4:A 509 87 0.0961 0.0727 0.4253 3.57e-13 2aj4:B
14 4hac:A 312 342 0.2182 0.2692 0.2456 1.99e-10 4hac:B, 6mde:A, 6mdf:A, 6mdf:B
15 8teb:A 306 334 0.2156 0.2712 0.2485 8.02e-10
16 2oi2:A 285 77 0.0779 0.1053 0.3896 7.62e-08
17 2r42:A 383 237 0.1714 0.1723 0.2785 1.16e-04 1kvk:A
18 2hfu:A 326 72 0.0675 0.0798 0.3611 2.47e-04
19 8tfo:A 390 48 0.0468 0.0462 0.3750 1.7 8tfo:B
20 7d62:A 294 18 0.0312 0.0408 0.6667 3.7 7d62:B
21 7k1k:A 3604 31 0.0312 0.0033 0.3871 7.2 7k1b:A
22 7nfe:A 3585 31 0.0312 0.0033 0.3871 7.4
23 7k17:B 3645 31 0.0312 0.0033 0.3871 7.4 7k17:A
24 7otm:A 3656 31 0.0312 0.0033 0.3871 7.4 7otp:A, 7otv:A, 7otw:A, 7oty:A
25 8bot:A 3528 31 0.0312 0.0034 0.3871 7.5
26 7nfc:A 3562 31 0.0312 0.0034 0.3871 7.5 8bh3:S, 8bh3:A, 8bhv:A, 8bhv:F, 8bhy:A, 8bhy:S, 8bot:F, 8bot:S, 7nfc:F
27 7k1n:A 3634 31 0.0312 0.0033 0.3871 7.5 7z88:A
28 7k0y:A 3669 31 0.0312 0.0033 0.3871 7.5
29 6zha:A 3707 31 0.0312 0.0032 0.3871 7.5 6zh8:A
30 6zhe:F 3731 31 0.0312 0.0032 0.3871 7.5
31 8ez9:L 3662 31 0.0312 0.0033 0.3871 7.5 8ez9:C
32 7z87:A 3689 31 0.0312 0.0033 0.3871 7.5
33 7su3:A 3802 31 0.0312 0.0032 0.3871 7.6
34 8eza:L 3720 31 0.0312 0.0032 0.3871 7.7 8eza:C, 7lt3:C, 7lt3:L
35 8ezb:C 3724 31 0.0312 0.0032 0.3871 7.7 8ezb:L
36 7sud:A 3740 31 0.0312 0.0032 0.3871 7.7
37 6zhe:A 3768 31 0.0312 0.0032 0.3871 7.7
38 7sgl:A 3852 31 0.0312 0.0031 0.3871 8.0
39 5y3r:C 3636 31 0.0312 0.0033 0.3871 8.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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