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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LRLSYEKQDTLLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFLAEEGFYKFHNWFDDRAWYPLGRIIGG
TIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAGSY
DNEGIAIFCMLLTYYMWIKAVKTGSICWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAYCTVYCL
GTILSMQISFVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLNPQQFEVLFKISPWTGRFYSLLDPSYAKNNIPIIAS
VSEHQPTTWSSYYFDLQLLVFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGIGVSQVLST
YMKNLDISRKNEVASGMILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARIIFDDFREAYYWLRHNTPEDAKVMSWWDYG
YQITAMANRTILVDNNTWNNTHISRVGQAMASTEEKAYEIMRELDVSYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDTG
KHIKENDYYTPTGEFRVDREGSPVLLNCLMYKMCYYRFGQVYTEAKRPPGFDRVRNAEIGNKDFELDVLEEAYTTEHWLV
RIYKVKDLDNRGLSRT

The query sequence (length=656) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6s7o:A 656 656 1.0000 1.0000 1.0000 0.0 6ftg:5, 6fti:5, 6ftj:5, 8pn9:A
2 6s7t:A 706 671 0.6235 0.5793 0.6095 0.0
3 8agc:A 697 670 0.5579 0.5251 0.5463 0.0
4 6ezn:F 650 652 0.5213 0.5262 0.5245 0.0 8agb:A, 8age:A, 6c26:A, 7oci:F
5 7e9s:A 867 178 0.0716 0.0542 0.2640 1.45e-05 5gmy:A, 3wak:A
6 7e9s:A 867 106 0.0427 0.0323 0.2642 0.072 5gmy:A, 3wak:A
7 3waj:A 793 176 0.0701 0.0580 0.2614 2.21e-05
8 3waj:A 793 168 0.0640 0.0530 0.2500 0.036
9 3vu1:B 490 41 0.0274 0.0367 0.4390 0.013 3vu1:A
10 7zlg:A 662 183 0.0716 0.0710 0.2568 0.013 7zli:A, 7zlj:A
11 5ogl:A 707 411 0.1250 0.1160 0.1995 0.048 6gxc:A
12 3l6n:A 218 77 0.0366 0.1101 0.3117 0.23
13 3wov:A 457 28 0.0213 0.0306 0.5000 0.33
14 7b6w:AAA 438 85 0.0412 0.0616 0.3176 0.44
15 5d4c:K 231 103 0.0457 0.1299 0.2913 1.6 2a68:A, 2a68:B, 2a68:K, 2a68:L, 2a69:A, 2a69:B, 2a69:K, 2a69:L, 5d4c:B, 5d4c:L, 5d4d:L, 5e17:B, 5e18:B, 7eh0:B, 7eh1:B, 4g7h:B, 1iw7:A, 1iw7:B, 1iw7:K, 1iw7:L, 6kqd:B, 6kqd:K, 6kqe:B, 6kqf:B, 6kqg:B, 6kqh:B, 6kqm:B, 6kqn:B, 6l74:B, 6lts:B, 7mlb:B, 7mli:B, 7mlj:B, 4oin:B, 4oip:B, 7rdq:B, 1smy:A, 1smy:B, 5vo8:B, 8w8n:B, 8w8o:B, 8w8p:B, 5x21:A, 5x22:B, 5x22:L
16 5onm:A 138 68 0.0335 0.1594 0.3235 1.7 5onn:A, 5ono:A
17 3aag:A 267 65 0.0290 0.0712 0.2923 1.9
18 3rce:A 683 94 0.0366 0.0351 0.2553 3.4
19 1xdq:C 264 152 0.0579 0.1439 0.2500 4.8 1xdq:A, 1xdq:B, 1xdq:D, 1xdq:E
20 4y0k:A 405 26 0.0198 0.0321 0.5000 7.7 4y1b:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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