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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LQSLAILGATGSIGDSTLAIIRQHPNRYRIHALTGFSRVDKLLALAMEFHPVKICTSPDNYAQLSQKVTDAGLDTIILSG
DEGLIEIASDEAVDTVVAAIVGAAGLSSTLAAAGAGKRILLANKESLVMAGDLVIKTAKKHGATILPIDSEHNAIYQCLP
AAIQADNTAIHHTSYGIKKLWLTASGGSFLDKSIKQMQNASVKEAVNHPNWSMGQKISIDSATMMNKGLELIEACHLFDL
KEHQIQVVIHPNSVVHSLVEYVDGSFLAQLGTPDMKTPIAHALAYPERIKSGVMPLDLYQLGSLKFLAPDLDKFACLKLA
RYAARLGTGACIALNTANEIAVEAFLAEKICLTDIAVIVKACLDDKTIAQDYSQDFGDEVLGLERILTMDKKVRKIATAK
IKLLKQGD

The query sequence (length=408) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4zqg:A 408 408 1.0000 1.0000 1.0000 0.0 4zqf:A, 4zqf:B, 4zqg:B, 4zqh:A, 4zqh:B
2 7s04:A 396 402 0.5049 0.5202 0.5124 2.23e-136
3 5kqo:A 398 366 0.4608 0.4724 0.5137 1.30e-118 5kqo:B, 5krr:A, 5krr:B, 5ks1:A, 5ks1:B
4 3anl:A 400 404 0.4559 0.4650 0.4604 1.56e-111 3anl:B, 3anm:A, 3anm:B, 3ann:A, 3ann:B, 2egh:A, 2egh:B, 1jvs:A, 1jvs:B, 1ono:A, 1ono:B, 1onp:A, 1onp:B, 1q0h:A, 1q0l:A, 1q0q:A, 1q0q:B, 3r0i:A, 3r0i:B, 1t1r:A, 1t1r:B, 1t1s:A, 1t1s:B
5 5dul:B 390 405 0.4510 0.4718 0.4543 8.68e-108 5dul:A, 5dul:D, 3iie:A, 3iie:B
6 6mh5:B 375 390 0.4044 0.4400 0.4231 5.02e-101 6mh5:A
7 1r0l:B 379 404 0.4265 0.4591 0.4307 1.61e-100 1r0l:A, 1r0l:C, 1r0l:D
8 5dul:C 367 401 0.4240 0.4714 0.4314 1.70e-96
9 4gae:A 416 396 0.3799 0.3726 0.3914 3.07e-88 3au8:A, 3au8:B, 3au9:A, 3au9:B, 3aua:A, 3aua:B, 4gae:B, 5jaz:A, 5jaz:B, 5jbi:A, 5jbi:B, 5jc1:A, 5jc1:B, 5jmp:A, 5jmp:B, 5jmw:A, 5jmw:B, 5jnl:A, 5jnl:B, 8jnv:A, 8jnv:B, 8jnw:A, 8jnw:B, 5jo0:A, 5jo0:B, 4kp7:A, 4kp7:B, 3wqq:A, 3wqq:B, 3wqr:A, 3wqr:B, 3wqs:B, 4y67:A, 4y67:B, 4y6p:A, 4y6p:B, 4y6r:A, 4y6r:B, 4y6s:A, 4y6s:B
10 8s65:B 411 421 0.4069 0.4039 0.3943 3.92e-81 8s65:A
11 4aic:A 379 384 0.3456 0.3720 0.3672 6.14e-65 4a03:A, 4a03:B, 4aic:B, 2c82:A, 2c82:B, 2jcv:A, 2jcv:B, 2jcx:A, 2jcx:B, 2jd0:A, 2jd1:A, 2jd1:B, 2jd2:A, 2jd2:B, 4ooe:A, 4ooe:B, 4ooe:C, 4ooe:D, 4oof:A, 4oof:B, 3ras:A, 3ras:B, 4rcv:A, 4rcv:B, 2y1c:A, 2y1c:B, 2y1d:B, 2y1e:A, 2y1e:B, 2y1f:A, 2y1f:B, 2y1g:A, 2y1g:B, 3zhx:A, 3zhx:B, 3zhy:A, 3zhy:B, 3zhz:A, 3zi0:A, 3zi0:B
12 3a06:B 373 378 0.3113 0.3405 0.3360 2.09e-59 3a06:A, 3a14:A, 3a14:B
13 2y1d:A 359 386 0.3260 0.3705 0.3446 1.76e-55
14 3hsk:A 358 38 0.0368 0.0419 0.3947 0.14
15 1dbg:A 481 105 0.0662 0.0561 0.2571 1.6 1dbo:A, 1ofl:A, 1ofm:A
16 3nqw:A 178 69 0.0515 0.1180 0.3043 2.0 3nqw:B
17 6pdy:A 262 47 0.0343 0.0534 0.2979 5.9 6pe0:A
18 6pdw:D 299 47 0.0343 0.0468 0.2979 7.8 6pdw:B, 6pdw:C, 6pdw:E, 6pdw:F, 6pdy:F, 6pdy:C, 6pdy:D, 6pdy:E, 6pdy:B, 6pe0:B, 6pe0:C, 6pe0:D, 6pe0:E, 6pe0:F
19 2hvw:A 147 34 0.0319 0.0884 0.3824 8.6 5c2o:A, 5c2o:B, 2hvv:A, 2hvv:B, 2hvw:B, 2hvw:C
20 4z71:B 163 66 0.0441 0.1104 0.2727 9.4 5kde:A, 5kdf:A, 1wcf:A, 4z70:A, 4z70:B, 4z70:C, 4z71:A, 4z71:C, 4z72:A, 4z73:A, 4z73:B, 4z73:C, 4z73:D, 4z73:F, 4z73:G, 4z73:E, 4z73:H, 4z73:I, 4z73:J, 4z73:K, 4z73:L, 4z74:A, 4z74:B, 4z74:C, 4z74:D, 4z74:F, 4z74:G, 4z74:E, 4z74:H, 4z74:I, 4z74:J, 4z74:K, 4z74:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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