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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LPPKLLLVSFDGFRADYLKNYEFPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDAVTKKHFS
DSNDKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDVPIHDTISSYFMNYNSSVSFEERLNNITMWLNNSNPPVTFATL
YWEEPDASGHKYGPEDKENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYYTLI
DLSPVAAILPKINRTEVYNKLKNCSPHMNVYLKEDIPNRFYYQHNDRIQPIILVADEGWTIVLNESSQKLGDHGYDNSLP
SMHPFLAAHGPAFHKGYKHSTINIVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCI

The query sequence (length=379) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4lqy:A 379 379 1.0000 1.0000 1.0000 0.0 4lr2:A
2 5vem:A 383 374 0.5251 0.5196 0.5321 2.16e-134 5vem:B, 5vem:C
3 5ven:A 382 374 0.5092 0.5052 0.5160 2.56e-133 5ven:B, 5veo:A
4 4gtw:A 706 389 0.3984 0.2139 0.3882 9.76e-75 4gtw:B, 4gtx:A, 4gtx:B, 4gty:A, 4gty:B, 4gtz:A, 4gtz:B, 6xkd:B
5 6wev:AbA 817 390 0.3958 0.1836 0.3846 2.81e-74 8ghr:A, 8ghr:B, 6wet:AaA, 6wet:BaB, 6weu:AbA, 6weu:BbB, 6wev:BbB, 6wew:AbA, 6wew:BaB, 6wfj:AcA, 6wfj:BcB
6 6xkd:A 679 386 0.3931 0.2194 0.3860 1.25e-73
7 4b56:A 816 389 0.3984 0.1850 0.3882 1.30e-73 6aek:A, 6ael:A, 4b56:B
8 6f2t:B 722 393 0.3641 0.1911 0.3511 5.99e-70 6f2t:A, 6f2v:A, 6f2v:B, 6f2y:A, 6f2y:B, 6f30:A, 6f30:B, 6f33:A, 6f33:B
9 6c01:A 819 389 0.3641 0.1685 0.3548 1.03e-68 6c01:B, 6c02:A, 6c02:B
10 5gz4:A 804 391 0.3668 0.1729 0.3555 2.93e-68 7cba:A, 7cba:B, 5gz5:A
11 5egh:B 393 393 0.3404 0.3282 0.3282 1.35e-66 5ege:A, 5ege:B, 5ege:C, 5ege:D, 5egh:A
12 5tcd:A 388 386 0.3377 0.3299 0.3316 7.52e-65 5udy:A
13 2xrg:A 758 380 0.3456 0.1728 0.3447 3.57e-57
14 5s9m:A 809 400 0.3641 0.1706 0.3450 4.77e-57 8c3o:A, 5dlt:A, 9ent:A, 9eu5:A, 5hrt:A, 5ijq:A, 5ijs:A, 5lia:A, 3nkm:A, 3nkp:A, 5s9l:A, 5s9n:A, 6w35:A, 3wav:A, 3wax:A, 2xr9:A, 7z0n:AAA, 7z3k:AAA, 7z3l:AAA
15 3way:A 787 386 0.3456 0.1665 0.3394 1.29e-56 8c3o:B, 8c3p:A, 8c3p:B, 8c4w:A, 8c7r:A, 5dlv:A, 5dlv:B, 5dlw:A, 5inh:A, 5l0b:A, 5l0b:B, 5l0e:A, 5l0e:B, 5l0k:A, 5l0k:B, 6leh:A, 5lqq:A, 5m0d:A, 5m0e:A, 5m0m:A, 5m0s:A, 7mfh:A, 5mhp:A, 3nkn:A, 3nko:A, 3nkq:A, 3nkr:A, 5ohi:A, 5olb:A, 7p0k:AAA, 7p4j:A, 7p4o:A, 3waw:A, 6y5m:A, 4zg7:A
16 6g4g:D 781 391 0.3298 0.1601 0.3197 1.43e-55 6g4g:A
17 4zg9:B 764 400 0.3588 0.1780 0.3400 1.16e-53 5kxa:A, 5m7m:A, 4zg6:A, 4zg6:B, 4zg9:A, 4zga:A
18 7mw8:C 385 373 0.2929 0.2883 0.2976 3.73e-52 2gsn:A, 2gsn:B, 2gso:A, 2gso:B, 2gsu:A, 2gsu:B, 7mw8:A, 7mw8:D, 7mw8:B, 7mw8:E, 7mw8:F, 7n1s:A, 7n1s:B, 2rh6:A, 2rh6:B
19 6g4g:C 742 391 0.3245 0.1658 0.3146 7.88e-52
20 6g4g:B 759 389 0.3140 0.1568 0.3059 3.19e-49
21 5xwi:A 503 82 0.0712 0.0537 0.3293 7.55e-04
22 5xwk:A 530 82 0.0712 0.0509 0.3293 7.76e-04 3q3q:A
23 6s21:A 486 36 0.0475 0.0370 0.5000 0.002 6s21:B, 6s21:C
24 3szy:A 413 366 0.2137 0.1961 0.2213 0.003 3szz:A, 3t00:A, 3t01:A, 3t02:A
25 8di0:B 426 35 0.0422 0.0376 0.4571 0.027
26 7sno:A 506 42 0.0449 0.0336 0.4048 0.028
27 7lj2:A 507 42 0.0449 0.0335 0.4048 0.028 7lha:A, 7lha:B, 7lj2:B
28 6j66:B 476 69 0.0554 0.0441 0.3043 0.033 6j66:A
29 9fvt:A 519 48 0.0475 0.0347 0.3750 0.053 9fvt:B, 9fvt:C, 9fvt:D
30 4upi:A 548 34 0.0369 0.0255 0.4118 0.22
31 4upi:A 548 73 0.0580 0.0401 0.3014 1.7
32 7oz8:AAA 474 48 0.0449 0.0359 0.3542 0.34
33 7ana:AAA 475 38 0.0369 0.0295 0.3684 0.34 7ana:BBB, 7anb:AAA, 7anb:BBB
34 7bvy:A 333 70 0.0422 0.0480 0.2286 0.35 7bvz:A
35 2w8s:B 513 34 0.0343 0.0253 0.3824 0.48 2w8s:A, 2w8s:C, 2w8s:D
36 6t9m:AAA 350 34 0.0422 0.0457 0.4706 0.57
37 6hhm:A 459 30 0.0343 0.0283 0.4333 0.59
38 7aj0:A 501 34 0.0396 0.0299 0.4412 0.60 7aj0:B, 7aj0:C, 7aj0:D, 7aj0:E, 7aj0:F
39 2vqr:A 512 34 0.0317 0.0234 0.3529 0.68
40 4uph:A 504 33 0.0317 0.0238 0.3636 0.95 4uph:B, 4uph:C, 4uph:D
41 7an1:AAA 483 38 0.0343 0.0269 0.3421 0.97 7oqd:AAA
42 4uop:B 409 35 0.0290 0.0269 0.3143 1.4 4uop:A
43 7all:AAA 498 44 0.0369 0.0281 0.3182 1.6
44 7p24:AAA 494 36 0.0369 0.0283 0.3889 1.8
45 7o7g:A 627 80 0.0580 0.0351 0.2750 2.5 4lm8:A, 8qbq:A, 8qbz:A, 8qc9:A, 7qth:A
46 4upl:A 555 34 0.0317 0.0216 0.3529 3.2 4upl:C
47 4fdi:A 494 55 0.0449 0.0344 0.3091 3.4 4fdi:B, 4fdj:A, 4fdj:B
48 7oz9:BBB 483 50 0.0369 0.0290 0.2800 3.5 7oz9:AAA
49 1fsu:A 475 42 0.0290 0.0232 0.2619 3.6
50 7aih:Ab 260 25 0.0290 0.0423 0.4400 4.3 7am2:Ab, 7ane:Ab
51 8rq9:A 316 43 0.0369 0.0443 0.3256 4.9 8rq1:A, 8rq8:A, 8rq9:C, 8rqa:A, 8rqc:A, 8rqc:D
52 7vcf:A 1496 97 0.0660 0.0167 0.2577 5.9
53 1ei6:A 404 77 0.0554 0.0520 0.2727 6.2 1ei6:B, 1ei6:C, 1ei6:D
54 6pt4:B 473 30 0.0290 0.0233 0.3667 6.3 6pt4:A, 6pt6:B, 6pt6:A, 6pt9:A, 6pt9:B, 6ptk:A, 6ptk:B, 6ptk:C, 6ptk:D
55 1m3u:A 262 64 0.0501 0.0725 0.2969 6.5 1m3u:B, 1m3u:C, 1m3u:D, 1m3u:E, 1m3u:F, 1m3u:G, 1m3u:H, 1m3u:I, 1m3u:J
56 7oza:CCC 488 53 0.0369 0.0287 0.2642 6.8 7oza:AAA
57 1n2l:A 483 61 0.0449 0.0352 0.2787 7.3 1auk:A, 1e1z:P, 1e2s:P, 1e33:P, 1e3c:P, 1n2k:A
58 5tj3:A 520 76 0.0686 0.0500 0.3421 8.0 5too:A
59 3fvd:B 367 50 0.0422 0.0436 0.3200 9.0 3fvd:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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