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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LPLFSDQYIVVNGAPVIPSAKVPVLKKALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLD
LKHRLFLYTMKDPSSSLKSWLMDDKVRDQFVLQDDVKTSVFWNSMFNEEDSLVESRENWSTNYVRFSPKGTYLFSYHQQG
VTAWGGPNFDRLRRFYHPDVRNSSVSPNEKYLVTFSTEPIIVEEDNEFSPFTKKNEGHQLCIWDIASGLLMATFPVIKSP
YLKWPLVRWSYNDKYCARMVGDSLIVHDATKNFMPLEAKALKPSGIRDFSFAPEGVKLQPFRNGDEPSVLLAYWTPETNN
SACTATIAEVPRGRVLKTVNLVQVSNVTLHWQNQAEFLCFNVERHTKSGKTQFSNLQICRLTERDIPVEKVELKDSVFEF
GWEPHGNRFVTISVHEVADMNYAIPANTIRFYAPETKEKTDVIKRWSLVKEIPKTFANTVSWSPAGRFVVVGALVGPNMR
RSDLQFYDMDYPGEKNINDNNDVSASLKDVAHPTYSAATNITWDPSGRYVTAWSSSLKHKVEHGYKIFNIAGNLVKEDII
AGFKNFAWRPRP

The query sequence (length=572) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4uer:b 572 572 1.0000 1.0000 1.0000 0.0
2 6gsn:p 658 589 0.9913 0.8617 0.9626 0.0 8cah:p, 8cas:p, 6fyx:p, 6fyy:p, 6gsm:p, 6zce:p, 6zu9:p
3 8xxn:3B 536 569 0.3217 0.3433 0.3234 3.04e-95 6zon:B, 6zp4:B, 6zvj:B
4 8pj1:1 588 589 0.3269 0.3180 0.3175 1.01e-92 6fec:w, 2krb:A, 8oz0:I, 8pj2:1, 8pj3:1, 8pj5:1, 8pj6:1
5 2mb0:B 95 57 0.0402 0.2421 0.4035 1.87e-05
6 4ed5:B 169 53 0.0262 0.0888 0.2830 0.002 4ed5:A
7 4ed5:B 169 54 0.0332 0.1124 0.3519 0.042 4ed5:A
8 2x1f:A 94 54 0.0245 0.1489 0.2593 0.007 2km8:B, 2x1a:A
9 8i0v:4 161 51 0.0385 0.1366 0.4314 0.008
10 1fnx:H 174 73 0.0350 0.1149 0.2740 0.011 1fxl:A, 1g2e:A
11 1fnx:H 174 52 0.0315 0.1034 0.3462 0.070 1fxl:A, 1g2e:A
12 2xs2:A 87 56 0.0367 0.2414 0.3750 0.024 2xs5:A, 2xs5:B, 2xs7:A
13 2rra:A 99 55 0.0280 0.1616 0.2909 0.027 2kxn:B
14 8by6:B 152 55 0.0315 0.1184 0.3273 0.033 7abg:A1, 6d0y:A, 1h2t:Z, 1h2u:X, 1h2u:Y, 1n52:B, 5oo6:B, 5oo6:E, 5oo6:H, 5oo6:K, 5oo6:N, 5oo6:Q, 5oo6:T, 5oo6:W, 5oob:D, 5oob:J, 5oob:B, 5oob:G, 8pmp:B, 8pnt:B, 8srr:B, 8suy:B
15 7dvq:Y 140 31 0.0227 0.0929 0.4194 0.092 8i0p:Y, 8i0r:Y
16 2leb:A 101 52 0.0297 0.1683 0.3269 0.13 2lec:A
17 1wtb:A 79 44 0.0280 0.2025 0.3636 0.13 1x0f:A
18 2mgz:A 94 52 0.0315 0.1915 0.3462 0.14
19 7q33:A 93 56 0.0245 0.1505 0.2500 0.16 6pai:D, 6q0r:D, 6q0v:D, 6q0w:D, 6sj7:C, 6ud7:C, 6ue5:C
20 2cjk:A 167 61 0.0297 0.1018 0.2787 0.28 2km8:C
21 2cjk:A 167 57 0.0315 0.1078 0.3158 0.41 2km8:C
22 7zew:A 117 53 0.0297 0.1453 0.3208 0.36 7zex:A
23 4a8x:A 88 58 0.0280 0.1818 0.2759 0.37
24 2fy1:A 108 54 0.0315 0.1667 0.3333 0.65
25 7slp:B 321 44 0.0297 0.0530 0.3864 0.67 6d12:A, 6d12:B, 7slq:B, 4wkr:A, 4wkr:B
26 8xxm:3G 84 48 0.0262 0.1786 0.3125 0.69 5k0y:O, 8pj1:o, 8pj2:o, 8pj3:o, 8pj4:o, 8pj5:o, 8pj6:o
27 7o9j:B 307 75 0.0420 0.0782 0.3200 0.77 7o9j:A, 7o9l:A, 7o9l:B, 7odz:A, 7odz:B, 8ohy:A
28 5ju6:A 835 119 0.0577 0.0395 0.2773 0.90 5ju6:B, 5ju6:C, 5ju6:D
29 6r5k:H 394 54 0.0350 0.0508 0.3704 1.3 6r5k:D, 6r5k:F
30 5ith:A 80 51 0.0280 0.2000 0.3137 1.6 5o3j:A
31 9gpj:A 184 48 0.0280 0.0870 0.3333 1.8 6dcl:A, 6dcl:B, 9f4d:A, 9f4e:A, 9f4f:A, 9f4g:A, 9f4h:A, 9f4j:A, 9f4k:A, 9f4l:A, 9f4m:A, 9f4n:A, 9f4o:A, 9f4p:A, 9f4q:A, 9f4r:A, 9f4s:A, 9f4t:A, 9f4u:A, 9f4v:A, 9f4w:A, 9f4x:A, 9f4y:A, 9f4z:A, 9f50:A, 9f51:A, 9f52:A, 9f53:A, 9f54:A, 9f55:A, 9f5c:A, 9f5d:A, 9f5e:A, 9f5f:A, 9f5g:A, 9f5k:A, 9f7f:A, 9f7h:A, 5mpg:A, 5mpl:A, 1pgz:A, 1po6:A, 8rzv:A, 1u1k:A, 1u1l:A, 1u1m:A, 1u1n:A, 1u1o:A, 1u1p:A, 1u1q:A, 1u1r:A, 2up1:A, 4yoe:A
32 8qwt:A 331 55 0.0245 0.0423 0.2545 2.7
33 7dco:4 174 49 0.0245 0.0805 0.2857 2.8 6g90:R, 5gm6:e, 5nrl:R, 7oqb:R, 7oqe:R, 5zwm:4
34 8fkp:SH 150 53 0.0315 0.1200 0.3396 3.2 8fkq:SH, 8fkr:SH, 8fks:SH, 8fkt:SH, 8fku:SH, 8fkv:SH, 8fkw:SH, 8fkx:SH, 8fky:SH, 8fkz:SH, 8fl2:SH, 8fl6:SH, 8fla:SH, 8fld:SH, 8ine:t, 8inf:t, 8ipx:t, 8ipy:t, 8ir3:t
35 5mqf:o 223 53 0.0297 0.0762 0.3208 3.4 6id1:y, 7w59:y, 7w5a:y, 7w5b:y
36 8esq:o 137 50 0.0227 0.0949 0.2600 3.5 8esr:o, 8etg:o, 8eth:o, 8eti:o, 8eup:o, 8euy:o, 8ev3:o
37 6z1p:BE 447 182 0.0717 0.0917 0.2253 4.9
38 2z02:A 242 88 0.0402 0.0950 0.2614 5.4 2yzl:A, 2z02:B
39 8y6o:W 167 77 0.0367 0.1257 0.2727 5.6
40 2n82:B 104 48 0.0262 0.1442 0.3125 6.4 2err:A, 7vrl:B
41 5x8p:v 190 57 0.0280 0.0842 0.2807 7.4 5mmj:v, 5mmm:v, 5x8r:v
42 6m75:A 167 46 0.0262 0.0898 0.3261 7.6
43 7fgp:A 379 41 0.0245 0.0369 0.3415 7.9 7fgp:B
44 5ta9:A 369 31 0.0192 0.0298 0.3548 8.2 5ta9:B, 5ta9:C, 5ta9:D
45 6xh2:A 93 52 0.0262 0.1613 0.2885 8.7 6cmn:A, 3k0j:D, 3k0j:C, 6xh0:A, 6xh1:A, 6xh3:A
46 4ak7:B 373 40 0.0210 0.0322 0.3000 8.7 4ak7:A
47 5en1:A 184 48 0.0262 0.0815 0.3125 9.6 8hni:A, 8hni:B, 8hni:G, 8hni:I, 8hni:H, 8hni:E, 8hni:K, 8hni:C, 8hni:D, 8hni:J, 8hni:F, 8hni:L, 5ho4:A, 7wm3:A, 7wm3:B, 7wm3:C, 7wm3:D, 5wwe:A, 5wwf:A, 5wwf:C, 5wwg:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218