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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LPKAEAKELSAFVQSCVEYKTNVCFTDVAAYESNQKGVLSSGLAVLVGTHKQLRDPAVQRLPFYNPAVAEAIERVKEGGT
YGVLVEGLANAAGSKFVRVVVGEVPTKASRNNCPARPDVVTALVTAALDEVKEPNTTVDVFVLSNAVLPIAAAVARCGKH
NFSAKDGAAAAAYNSGKVSRLQVVFPEPPAIPPKDLEAVATSTQLCQRLVDAPPNLLTTATFTEIAQGYAKALGFDVDVI
CGDDLCERGYGGIYSVGKAAFEAPRLVTLLYTPKGTPVKKVSLVGKGIVYDCGGLALKPADYMKLMKHDMGGAAAVFCGF
LTAVRLQQPVQLSCTLCLAENAIGPKSYRNDDIIVMKSGKTVEVINTDAEGRIVLGDGVFHATNELSFTPDVVIDMATLT
GAQGIATGRHHAGLYVNEEGAEAAMLRAGRESGETCFPVLYCPEYHEPEFKSNHADMTNLMERRDNAGVSCAGYFITTHL
SPKFTGAHIHVDLAYPVFNSNGATGFGPALLTEYFRKL

The query sequence (length=518) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5ntd:G 520 518 1.0000 0.9962 1.0000 0.0 4efd:F, 5nsm:A, 5nsm:B, 5nsm:C, 5nsm:D, 5nsm:E, 5nsm:F, 5nsm:G, 5nsm:H, 5nsm:I, 5nsm:J, 5nsm:K, 5nsm:L, 5nsq:A, 5nsq:B, 5nsq:C, 5nsq:D, 5nsq:E, 5nsq:F, 5ntd:A, 5ntd:B, 5ntd:D, 5ntd:C, 5ntd:E, 5ntd:F, 5ntd:H, 5ntd:I, 5ntd:J, 5ntd:K, 5ntd:L
2 5ntg:A 512 509 0.6641 0.6719 0.6758 0.0 5ntg:B
3 5nth:A 537 536 0.5232 0.5047 0.5056 6.23e-156
4 2hc9:A 489 426 0.3012 0.3190 0.3662 1.59e-65
5 3h8f:A 497 329 0.2394 0.2495 0.3769 1.51e-49 3h8f:B, 3h8f:C, 3h8f:D, 3h8f:E, 3h8f:F, 3h8g:F, 3h8g:A, 3h8g:B, 3h8g:C, 3h8g:D, 3h8g:E
6 4zla:A 485 332 0.2317 0.2474 0.3614 2.89e-48 4zi6:A, 4zi6:B, 4zi6:C, 4zi6:D, 4zi6:E, 4zi6:F, 4zla:B, 4zla:C, 4zla:D, 4zla:E, 4zla:F
7 8pz0:A 500 327 0.2336 0.2420 0.3700 1.20e-46 8pzm:A, 8pzy:A, 8pzy:B, 8pzy:C, 8pzy:D, 8pzy:E, 8pzy:F
8 6ov8:A 429 346 0.2162 0.2611 0.3237 2.33e-43 6oad:A, 6oad:B, 6oad:C, 6oad:D, 6oad:E, 6oad:F, 6oad:G, 6oad:H, 6oad:I, 6oad:J, 6oad:K, 6oad:L, 6ov8:B, 6ov8:C, 6ov8:D, 6ov8:E, 6ov8:F
9 1gyt:A 503 311 0.2066 0.2127 0.3441 1.10e-41 1gyt:B, 1gyt:C, 1gyt:D, 1gyt:E, 1gyt:F, 1gyt:G, 1gyt:H, 1gyt:I, 1gyt:J, 1gyt:K, 1gyt:L
10 8d1x:D 469 330 0.2259 0.2495 0.3545 3.40e-40 8d1x:A, 8d1x:B, 8d1x:C, 8d1x:E, 8d1x:F
11 8ez4:C 525 319 0.2046 0.2019 0.3323 3.45e-40 5cbm:A, 5cbm:B, 5cbm:C, 5cbm:D, 5cbm:E, 5cbm:F, 5cbm:G, 5cbm:H, 5cbm:I, 5cbm:J, 5cbm:K, 5cbm:L, 6ee2:A, 6ee2:B, 6ee2:C, 6ee2:D, 6ee2:E, 6ee2:F, 6ee2:G, 6ee2:H, 6ee2:I, 6ee2:J, 6ee2:K, 6ee2:L, 6eee:A, 6eee:B, 6eee:C, 6eee:D, 6eee:E, 6eee:F, 6eee:G, 6eee:H, 6eee:I, 6eee:J, 6eee:K, 6eee:L, 8ez4:A, 8ez4:B, 8ez4:D, 8ez4:E, 8ez4:F, 8ez4:G, 8ez4:H, 8ez4:I, 8ez4:J, 8ez4:K, 8ez4:L, 4k3n:A, 4k3n:B, 4k3n:C, 4k3n:D, 4k3n:E, 4k3n:F, 4k3n:G, 4k3n:H, 4k3n:I, 4k3n:J, 4k3n:K, 4k3n:L, 3kqx:A, 3kqx:B, 3kqx:C, 3kqx:D, 3kqx:E, 3kqx:F, 3kqx:G, 3kqx:H, 3kqx:I, 3kqx:J, 3kqx:K, 3kqx:L, 3kqz:A, 3kqz:B, 3kqz:C, 3kqz:D, 3kqz:E, 3kqz:F, 3kqz:G, 3kqz:H, 3kqz:I, 3kqz:J, 3kqz:K, 3kqz:L, 3kr4:A, 3kr4:B, 3kr4:C, 3kr4:D, 3kr4:E, 3kr4:F, 3kr4:G, 3kr4:H, 3kr4:I, 3kr4:J, 3kr4:K, 3kr4:L, 3kr5:A, 3kr5:B, 3kr5:C, 3kr5:D, 3kr5:E, 3kr5:F, 3kr5:G, 3kr5:H, 3kr5:I, 3kr5:J, 3kr5:K, 3kr5:L, 4r6t:A, 4r6t:B, 4r6t:C, 4r6t:D, 4r6t:E, 4r6t:F, 4r6t:G, 4r6t:H, 4r6t:I, 4r6t:J, 4r6t:K, 4r6t:L, 4r76:A, 4r76:B, 4r76:C, 4r76:D, 4r76:E, 4r76:F, 4r76:G, 4r76:H, 4r76:I, 4r76:J, 4r76:K, 4r76:L, 4r7m:A, 4r7m:B, 4r7m:C, 4r7m:D, 4r7m:E, 4r7m:F, 4r7m:G, 4r7m:H, 4r7m:I, 4r7m:J, 4r7m:K, 4r7m:L, 7rie:A, 7rie:B, 7rie:C, 7rie:D, 7rie:E, 7rie:F, 7rie:G, 7rie:H, 7rie:I, 7rie:J, 7rie:K, 7rie:L, 7srv:A, 7srv:B, 7srv:C, 7srv:D, 7srv:E, 7srv:F, 8svm:A, 8svm:B, 8svm:C, 8svm:D, 8svm:E, 8svm:F, 8svm:G, 8svm:H, 8svm:I, 8svm:J, 8svm:K, 8svm:L, 8sw9:A, 8sw9:B, 8sw9:C, 8sw9:D, 8sw9:E, 8sw9:F, 8sw9:G, 8sw9:H, 8sw9:I, 8sw9:J, 8sw9:K, 8sw9:L, 7t3v:A, 7t3v:B, 7t3v:C, 7t3v:D, 7t3v:E, 7t3v:F, 3t8w:A, 3t8w:B, 3t8w:E, 3t8w:C, 3t8w:D, 3t8w:F, 3t8w:G, 3t8w:H, 3t8w:K, 3t8w:I, 3t8w:J, 3t8w:L, 4x2t:A, 4x2t:B, 4x2t:C, 4x2t:D, 4x2t:E, 4x2t:F, 4x2t:G, 4x2t:H, 4x2t:I, 4x2t:J, 4x2t:K, 4x2t:L, 4zx8:A, 4zx8:B, 4zx8:C, 4zx8:D, 4zx8:E, 4zx8:F, 4zx8:G, 4zx8:H, 4zx8:I, 4zx8:J, 4zx8:K, 4zx8:L, 4zx9:A, 4zx9:B, 4zx9:C, 4zx9:D, 4zx9:E, 4zx9:F, 4zx9:G, 4zx9:H, 4zx9:I, 4zx9:J, 4zx9:K, 4zx9:L, 4zy0:A, 4zy0:B, 4zy0:C, 4zy0:D, 4zy0:E, 4zy0:F, 4zy0:G, 4zy0:H, 4zy0:I, 4zy0:J, 4zy0:K, 4zy0:L, 4zy1:A, 4zy1:B, 4zy1:C, 4zy1:D, 4zy1:E, 4zy1:F, 4zy1:G, 4zy1:H, 4zy1:I, 4zy1:J, 4zy1:K, 4zy1:L, 4zy2:A, 4zy2:B, 4zy2:C, 4zy2:D, 4zy2:E, 4zy2:F, 4zy2:G, 4zy2:H, 4zy2:I, 4zy2:J, 4zy2:K, 4zy2:L, 4zyq:A, 4zyq:B, 4zyq:C, 4zyq:D, 4zyq:E, 4zyq:F, 4zyq:G, 4zyq:H, 4zyq:I, 4zyq:J, 4zyq:K, 4zyq:L
12 7y1s:A 494 312 0.1950 0.2045 0.3237 1.11e-39
13 6ome:A 499 333 0.2027 0.2104 0.3153 1.32e-39
14 2ewb:A 486 308 0.1892 0.2016 0.3182 5.12e-39 1bll:E, 1bpm:A, 1bpn:A, 2j9a:A, 1lam:A, 1lan:A, 1lap:A, 1lcp:A, 1lcp:B
15 5lhk:A 455 329 0.2162 0.2462 0.3404 2.32e-37
16 3jru:B 490 325 0.2085 0.2204 0.3323 4.93e-37 3jru:A
17 6wvv:K 440 317 0.1931 0.2273 0.3155 5.36e-35
18 6wvv:F 497 317 0.1911 0.1992 0.3123 9.31e-35 6wvv:G, 6wvv:H, 6wvv:I, 6wvv:J, 6wvv:L
19 7k5k:A 545 322 0.1911 0.1817 0.3075 6.07e-34 7k5k:B, 7k5k:C, 7k5k:D, 7k5k:E, 7k5k:F, 6wvv:A, 6wvv:B, 6wvv:C, 6wvv:D, 6wvv:E
20 4ksi:A 517 327 0.2085 0.2089 0.3303 3.32e-28 5d8n:A, 5d8n:B, 5d8n:C
21 7l1k:B 660 82 0.0444 0.0348 0.2805 0.93
22 5a8r:L 263 146 0.0637 0.1255 0.2260 3.4 5a8r:F, 5a8r:C, 5a8r:I, 5a8w:F, 5a8w:C, 5a8w:I, 5a8w:L
23 8fcj:B 216 66 0.0367 0.0880 0.2879 7.0 8fcu:B, 8fd2:B, 8fd3:B, 8ff4:B, 8ff5:B
24 4nmy:A 299 53 0.0328 0.0569 0.3208 7.8 4nmy:B
25 1uf2:A 967 85 0.0463 0.0248 0.2824 7.8
26 8fwg:n1 299 26 0.0251 0.0435 0.5000 9.5 8fwg:k1, 8fwg:g1, 8fwg:r1, 8fwg:o1, 8fwg:h1, 8fwg:k2, 8fwg:n2, 8fwg:g2, 8fwg:r2, 8fwg:o2, 8fwg:h2, 8fwg:k5, 8fwg:n5, 8fwg:g5, 8fwg:r5, 8fwg:o5, 8fwg:h5, 8fwg:k6, 8fwg:n6, 8fwg:g6, 8fwg:r6, 8fwg:o6, 8fwg:h6, 8fwg:k7, 8fwg:n7, 8fwg:g7, 8fwg:r7, 8fwg:o7, 8fwg:h7, 8fxp:i, 8fxp:j, 8fxp:k, 8fxp:n, 8fxp:g, 8fxp:r, 8fxp:o, 8fxp:h, 8fxp:w, 8fxp:y, 8fxp:x, 8fxp:AB, 8fxp:AC, 8fxp:AG, 8fxp:AJ, 8fxp:AF, 8fxp:AA, 8fxr:k1, 8fxr:n1, 8fxr:o1, 8fxr:g1, 8fxr:r1, 8fxr:h1, 8fxr:k2, 8fxr:n2, 8fxr:g2, 8fxr:r2, 8fxr:o2, 8fxr:h2, 8fxr:k5, 8fxr:n5, 8fxr:g5, 8fxr:r5, 8fxr:o5, 8fxr:h5, 8fxr:k6, 8fxr:n6, 8fxr:g6, 8fxr:r6, 8fxr:o6, 8fxr:h6, 8fxr:k7, 8fxr:n7, 8fxr:g7, 8fxr:r7, 8fxr:o7, 8fxr:h7
27 3pu9:A 236 132 0.0676 0.1483 0.2652 10.0 3pu9:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218