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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCE
TIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFP
EGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLVRVE

The query sequence (length=221) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4kbz:A 231 223 0.9910 0.9481 0.9821 8.72e-165 5a3u:B, 5a3u:C, 4bqw:A, 4bqx:A, 4bqy:A, 2g19:A, 2g1m:A, 2hbt:A, 2hbu:A, 3hqr:A, 3hqu:A, 4jzr:A, 5l9b:A, 5l9b:B, 5l9r:A, 5l9v:A, 5l9v:B, 5la9:A, 5la9:B, 5las:A, 5las:B, 5lat:A, 5lb6:A, 5lbb:A, 5lbc:A, 5lbe:A, 5lbf:A, 6nmq:A, 3ouh:A, 3oui:A, 3ouj:A, 5ox5:A, 5ox6:A, 7q5v:A, 7q5x:A, 8q5s:A, 8q64:A, 8q6d:A, 8q6e:A, 6st3:A, 6st3:B, 7ujv:B, 7ump:A, 4uwd:A, 5v18:A, 2y33:A, 2y34:A, 6yvt:B, 6yvt:D, 6yvw:A, 6yvx:A, 6yvz:A, 6yw0:A, 6yw1:A, 6yw2:A, 6yw3:A, 6yw4:A, 6zbn:B, 6zbn:D, 6zbo:A, 6zbo:C, 6zbo:D
2 5a3u:A 215 226 0.9050 0.9302 0.8850 4.75e-145 8j1k:A, 6qgv:A, 6yvt:A, 6yvt:C, 6yvt:E, 6yvt:F, 6zbn:A, 6zbn:C, 6zbn:E, 6zbn:F, 6zbo:B, 6zbo:E, 6zbo:F
3 5v1b:A 226 212 0.6787 0.6637 0.7075 3.17e-111
4 6f0w:A 220 200 0.4977 0.5000 0.5500 1.08e-80 6ey1:A
5 6iuq:B 296 189 0.2308 0.1723 0.2698 8.32e-11 6iuq:A
6 4iw3:A 201 198 0.2398 0.2637 0.2677 9.65e-08 4iw3:J, 4j25:E, 4j25:F, 4j25:G, 4j25:H
7 4j25:A 181 140 0.1900 0.2320 0.3000 6.68e-05 4j25:B, 4j25:C, 4j25:D
8 8k0e:A 646 97 0.1312 0.0449 0.2990 0.18 8k0f:A, 8k0m:A, 8k17:A, 8kc9:A
9 5xdc:B 402 111 0.1493 0.0821 0.2973 1.00 5xdb:A, 5xdb:B, 5xdb:C, 5xdb:D, 5xdc:A, 5xdc:C, 5xdc:D, 5xdd:A, 5xdd:B, 5xdd:C, 5xdd:D, 5xde:A, 5xde:B, 5xde:C, 5xde:D, 5xdg:A, 5xdg:B, 5xdg:C, 5xdg:D
10 6kc4:A 101 62 0.0860 0.1881 0.3065 1.3 6kc4:C, 6kc4:E, 6kc4:G, 6kc4:I, 6kc4:K
11 8gjz:B 182 42 0.0633 0.0769 0.3333 1.8 8efm:A, 8efm:B, 8gjz:A
12 7ohx:W 122 63 0.0860 0.1557 0.3016 2.7
13 6gfu:A 386 93 0.1312 0.0751 0.3118 3.3 5w76:A, 5w7q:A
14 3ly1:D 354 72 0.0950 0.0593 0.2917 3.6 3ly1:A, 3ly1:B, 3ly1:C
15 8u7h:C 1111 84 0.0905 0.0180 0.2381 3.9
16 4nhy:A 461 79 0.0905 0.0434 0.2532 4.5 4nhx:A, 4nhy:B, 4nhy:C, 4nhy:D
17 8ppb:A 276 75 0.0860 0.0688 0.2533 5.0 8pp8:A, 8pp8:B, 8pp9:A, 8pp9:B, 8ppa:A, 8ppa:B, 8ppb:B, 8ppc:A, 8ppc:B, 8ppd:A, 8ppd:B, 8ppe:A, 8ppe:B, 8ppf:A, 8ppf:B, 8ppg:A, 8pph:A, 8pph:B, 8ppi:A, 8ppi:B, 8ppj:A, 8ppj:B, 1tzd:A, 1tzd:B, 1w2c:A, 1w2c:B, 1w2d:A, 1w2d:B
18 5n0k:A 1034 44 0.0633 0.0135 0.3182 5.2 5n4l:A, 5n4l:B
19 8ppg:B 243 76 0.0860 0.0782 0.2500 8.3
20 9cc9:A 850 60 0.0724 0.0188 0.2667 8.5 9cc8:A, 9cc8:B, 9cc8:C, 9cc8:D, 9cc8:E, 9cc8:F, 9cc9:B, 9cc9:C, 9cc9:D, 9cc9:E, 9cc9:F, 9cc9:G, 9cc9:H, 9cc9:I, 9cc9:J, 9cc9:K, 9cc9:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218