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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LMPKKNRIAIYELLFKEGVMVAKKDVHLAKHPELADKNVPNLHVMKAMQSLKSCGYVKEQFAWRHFYWYLTNEGIQYLRD
FLHLPPEIVPATL

The query sequence (length=93) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 9bkd:a 99 93 0.9570 0.8990 0.9570 1.89e-63 7a01:E3, 7a09:u, 5a2q:K, 5aj0:BK, 9bdl:AS10, 9bdn:AS10, 9bdp:AS10, 8bhf:L3, 9bln:a, 8btk:Aj, 7cpu:SK, 7cpv:SK, 4d5l:K, 4d61:K, 6d90:LL, 6d9j:LL, 9f1b:Aj, 9f1c:Aj, 9f1d:Aj, 6fec:t, 5flx:K, 6g51:K, 6g53:K, 6g5h:K, 6g5i:K, 8g5y:SK, 8g5z:SK, 8g60:SK, 8g61:SK, 8g6j:SK, 8glp:SK, 6gz3:BK, 6gz4:BK, 6gz5:BK, 6hcf:L1, 6hcj:L2, 6hcm:L1, 6hcq:L2, 8ifd:2u, 8ife:2u, 6ip5:2u, 6ip6:2u, 6ip8:2u, 3j7p:SK, 3j7r:SK, 3jag:KK, 3jah:KK, 3jai:KK, 3jaj:SK, 3jan:SK, 8jdj:7, 8jdk:7, 8jdl:7, 8jdm:7, 7jqb:L, 7jqc:L, 5k0y:t, 8k2c:SK, 7k5i:K, 4kzx:K, 4kzy:K, 4kzz:K, 5lks:SK, 7ls1:v2, 7ls2:v2, 5lzs:KK, 5lzt:KK, 5lzu:KK, 5lzv:KK, 5lzw:KK, 5lzx:KK, 5lzy:KK, 5lzz:KK, 7mdz:KK, 6mtb:KK, 6mtc:KK, 6mtd:KK, 6mte:KK, 7nwg:L2, 7nwh:KK, 7nwi:KK, 7o7y:Aj, 7o7z:Aj, 7o80:Aj, 7o81:Aj, 5oa3:K, 6ole:SK, 6olf:SK, 6olg:BK, 6oli:SK, 6olz:BK, 6om0:SK, 6om7:SK, 7oya:K2, 7oyb:K2, 7oyc:K2, 7oyd:KK, 8oz0:i, 8p03:M, 8p09:M, 8p2k:Aj, 6p4g:L, 6p4h:L, 6p5i:L, 6p5j:L, 6p5k:L, 6p5n:L, 8pj1:a, 8pj2:a, 8pj3:a, 8pj4:a, 8pj5:a, 8pj6:a, 8ppk:K, 8ppl:AK, 8q7z:Aj, 8q87:Aj, 7qgg:SK, 8qoi:SK, 7qp6:a, 7qp7:a, 7qvp:SK, 7qvp:RK, 6qzp:SK, 7r4x:K, 6r5q:SS, 6r6g:SS, 6r6p:SS, 6r7q:SS, 8scb:KK, 6sgc:L1, 7syg:L, 7syh:L, 7syi:L, 7syj:L, 7syk:L, 7syl:L, 7sym:L, 7syn:L, 7syo:L, 7syp:L, 7syq:L, 7syr:L, 7sys:L, 7syt:L, 7syu:L, 7syv:L, 7syw:L, 7syx:L, 5t2c:Av, 8t4s:K, 7toq:AS10, 7tor:AS10, 7tql:M, 7ucj:KK, 7uck:KK, 4ug0:SK, 4ujc:CK, 4ujd:CK, 4uje:BK, 4v6x:AK, 5vyc:K1, 5vyc:K2, 5vyc:K3, 5vyc:K4, 5vyc:K5, 5vyc:K6, 6w2s:L, 6w2t:L, 6xa1:SK, 7xnx:SK, 7xny:SK, 8xsx:SK, 8xsy:SK, 8xsz:SK, 8xxl:SK, 8xxm:SK, 8xxn:SK, 6y0g:SK, 8y0w:SK, 8y0x:SK, 6y2l:SK, 6y57:SK, 6yal:M, 6yam:M, 6yan:M, 6ybs:a, 8yoo:SK, 8yop:SK, 6z6l:SK, 6z6m:SK, 6z6n:SK, 7zjw:SV, 7zjx:SV, 6zlw:M, 6zm7:SK, 6zme:SK, 6zmi:SK, 6zmo:SK, 6zmt:M, 6zmw:a, 6zn5:M, 6zoj:K, 6zol:K, 6zon:u, 6zp4:u, 6zuo:K, 6zv6:K, 6zvh:K, 6zvj:u, 6zvk:E3, 6zxd:K, 6zxe:K, 6zxf:K, 6zxg:K, 6zxh:K
2 6xu6:AK 90 91 0.7204 0.7444 0.7363 9.89e-46 6xu7:AK, 6xu8:AK
3 4v6w:AK 95 93 0.7204 0.7053 0.7204 2.15e-43
4 4v7e:BK 96 93 0.6022 0.5833 0.6022 2.99e-37 8ip8:da, 8ip9:da, 8ipa:da, 8ipb:da, 8jiw:BK, 8r57:K
5 7qiy:F 92 93 0.6129 0.6196 0.6129 8.31e-37 8auv:l, 8b2l:l1, 7qiz:PA
6 6zj3:SN 92 93 0.6129 0.6196 0.6129 7.04e-36
7 5xxu:K 94 93 0.5484 0.5426 0.5484 4.31e-34
8 8bn3:C0 96 92 0.5699 0.5521 0.5761 7.98e-34 7a1g:C, 7b7d:C, 8bqd:C, 8bqx:C, 8cah:C, 8cas:D, 8ccs:n, 8cdl:n, 8cdr:n, 8cf5:n, 8cku:n, 5dat:C0, 5dat:c0, 5dc3:C0, 5dc3:c0, 5dge:C0, 5dge:c0, 5dgf:C0, 5dgf:c0, 5dgv:C0, 5dgv:c0, 8eub:BK, 8evp:BK, 8evq:BK, 8evr:BK, 8evs:BK, 8evt:BK, 8ewb:BK, 8ewc:BK, 5fci:C0, 6gq1:AA, 6gqb:AA, 6gqv:AA, 6hhq:L, 6hhq:c0, 5i4l:C0, 5i4l:c0, 6i7o:C, 6i7o:Cb, 3j6x:10, 3j6y:10, 3j77:10, 3j78:10, 5juo:HB, 5jup:HB, 5jus:HB, 5jut:HB, 5juu:HB, 8k2d:SK, 8k82:SK, 5m1j:K2, 5mc6:C, 5mei:c0, 5mei:L, 7mpi:BK, 7mpj:BK, 7n8b:BK, 5ndg:C0, 5ndg:c0, 5ndv:C0, 5ndv:c0, 5ndw:C0, 5ndw:c0, 7nrc:SC, 7nrd:SC, 5obm:C0, 5obm:c0, 5on6:c0, 5on6:L, 7osa:eS10, 6q8y:C, 6rbe:K, 7rr5:SK, 6s47:BL, 6snt:K, 6sv4:C, 6sv4:Cb, 6sv4:Cc, 6t4q:SK, 6t7i:SK, 6t7t:SK, 6t83:Kb, 6t83:l, 5tbw:L, 5tbw:c0, 6tb3:C, 5tga:C0, 5tgm:C0, 5tgm:c0, 6tnu:C, 4u3m:C0, 4u3m:c0, 4u3n:C0, 4u3n:c0, 4u3u:C0, 4u3u:c0, 4u4n:C0, 4u4n:c0, 4u4o:C0, 4u4o:c0, 4u4q:C0, 4u4q:c0, 4u4r:C0, 4u4r:c0, 4u4u:C0, 4u4u:c0, 4u4y:C0, 4u4y:c0, 4u4z:C0, 4u4z:c0, 4u50:C0, 4u50:c0, 4u51:C0, 4u51:c0, 4u52:C0, 4u52:c0, 4u53:C0, 4u53:c0, 4u55:C0, 4u55:c0, 4u56:C0, 4u56:c0, 4u6f:C0, 4u6f:c0, 4uer:7, 4v88:AK, 4v88:CK, 4v8y:AK, 4v8z:AK, 4v92:BK, 6wdr:K, 6woo:KK, 6xiq:AA, 6xir:AA, 6z6j:SK, 6z6k:SK, 6zce:L, 7zpq:AK, 7zrs:AK, 6zu9:D, 7zuw:AK, 7zux:DK, 6zvi:s, 7zw0:sC
9 9bh5:AK 93 93 0.5699 0.5699 0.5699 2.55e-32 9cai:AK
10 6fyx:K 96 92 0.5376 0.5208 0.5435 2.62e-30 6fyy:K, 6gsm:K, 6gsn:K, 8i7j:K, 5it7:K, 5it9:K, 3j80:K, 3j81:K, 3jam:K, 3jap:K, 8rw1:K, 8s8d:K, 8s8e:K, 8s8f:K, 8s8g:K, 8s8h:K, 8s8i:K, 8s8j:K, 6uz7:K
11 5fci:c0 96 85 0.5161 0.5000 0.5647 3.59e-30 5fcj:C0, 5fcj:c0, 5lyb:C0, 5lyb:c0, 5tga:c0
12 7r81:L2 90 92 0.5376 0.5556 0.5435 4.96e-30 7olc:SK, 7old:SK, 8oo0:SK, 7z3n:SK, 7z3o:SK
13 8c3a:M 98 92 0.4946 0.4694 0.5000 5.48e-28 8c3a:CX, 8cgn:n, 8cq7:M, 8cq7:CX, 8cqw:M, 8cqw:CX, 8cre:M, 8cre:CX, 8oeq:M, 8oeq:CX, 7pzy:L, 7q08:L, 7q0f:L, 7q0p:L, 7q0r:L, 8q5i:L
14 7ase:N 93 91 0.4731 0.4731 0.4835 1.10e-26 5opt:n
15 3j7a:O 79 79 0.4624 0.5443 0.5443 2.66e-26 3jbn:O, 3jbo:O, 3jbp:O, 6okk:O, 8tpu:SO
16 4v8m:AD 103 93 0.4839 0.4369 0.4839 6.37e-26 8ova:AD, 8ove:AD
17 8a98:SN 101 93 0.4516 0.4158 0.4516 1.62e-24 8a3w:SN, 6az1:N, 8ovj:SN, 8rxh:SN, 8rxx:SN, 5t2a:AD
18 7qca:SK0 91 91 0.3656 0.3736 0.3736 2.61e-14 8p5d:SK0, 8p60:SK0, 8p60:RK0
19 4v5o:A7 104 91 0.3763 0.3365 0.3846 6.79e-14 4bts:A7, 4bts:B7, 4bts:C7, 4bts:D7, 4v5o:B7
20 5xyi:K 90 92 0.3441 0.3556 0.3478 4.03e-12
21 6zu5:SK0 74 78 0.3118 0.3919 0.3718 2.08e-11
22 8bsj:SL 109 97 0.3656 0.3119 0.3505 6.99e-11 8br8:SL, 8brm:SL, 8bsi:SL, 8btd:SL, 8btr:SL, 8fvy:K, 8g4s:K
23 7pwf:K 83 84 0.3441 0.3855 0.3810 3.89e-09
24 6rm3:SK0 85 51 0.1828 0.2000 0.3333 5.99e-07
25 7qep:C0 81 58 0.2473 0.2840 0.3966 5.15e-06
26 8ceh:n 33 21 0.1290 0.3636 0.5714 0.027 8cg8:n, 8civ:n, 8cmj:n, 7osm:eS10
27 4nur:A 633 49 0.2151 0.0316 0.4082 0.20 4nur:B
28 6er4:A 194 75 0.2366 0.1134 0.2933 0.30 6er3:A, 6er3:B, 6er4:B
29 6xk2:A 320 15 0.0753 0.0219 0.4667 2.0 6xk2:B, 6xk2:C, 6xk2:D
30 5fg9:V 230 34 0.1398 0.0565 0.3824 4.3 5ahj:H, 5ahj:V, 3bdm:H, 3bdm:V, 5bou:H, 5bou:V, 8bw1:H, 8bw1:V, 5bxl:H, 5bxl:V, 5bxn:H, 5bxn:V, 5cgf:V, 5cgg:V, 5cgh:V, 5cgi:H, 5cgi:V, 5cz4:V, 5cz5:H, 5cz5:V, 5cz6:H, 5cz6:V, 5cz7:H, 5cz7:V, 5cz8:H, 5cz8:V, 5cz9:H, 5cz9:V, 5cza:V, 5d0s:H, 5d0s:V, 5d0t:V, 5d0v:H, 5d0v:V, 5d0w:V, 5d0x:H, 5d0x:V, 5d0z:H, 5d0z:V, 3d29:H, 3d29:V, 5dki:H, 5dki:V, 5dkj:H, 5dkj:V, 3dy4:H, 3dy4:V, 6ef3:2, 4eu2:I, 4eu2:W, 2f16:H, 2f16:V, 2fak:H, 2fak:V, 5fg7:V, 5fga:V, 5fgd:H, 5fgd:V, 5fge:H, 5fge:V, 5fgf:H, 5fgf:V, 5fgg:H, 5fgg:V, 5fgh:H, 5fgh:V, 5fhs:H, 5fhs:V, 1fnt:I, 1fnt:W, 9fsv:H, 9fsv:V, 9ft0:H, 9ft0:V, 9ft1:H, 9ft1:V, 4fzc:H, 4fzc:V, 4fzg:H, 4fzg:V, 1g0u:H, 1g0u:V, 4g4s:I, 1g65:H, 6g7f:H, 6g7f:V, 6g8m:H, 6g8m:V, 6g8n:H, 6g8n:V, 4gk7:H, 4gk7:V, 6gop:H, 6gop:V, 2gpl:H, 2gpl:V, 3gpj:H, 3gpj:V, 3gpt:H, 3gpt:V, 3gpw:H, 3gpw:V, 6h39:V, 4hnp:H, 4hnp:V, 4hrc:H, 4hrc:V, 4hrd:H, 4hrd:V, 6hv3:V, 6hv4:H, 6hv4:V, 6hv5:H, 6hv5:V, 6hv7:H, 6hv7:V, 6hva:H, 6hva:V, 6hvr:H, 6hvr:V, 6hvs:H, 6hvs:V, 6hvt:H, 6hvt:V, 6hvu:H, 6hvu:V, 6hvv:H, 6hvv:V, 6hvw:H, 6hvw:V, 6hvx:H, 6hvx:V, 6hvy:H, 6hvy:V, 6hw0:H, 6hw0:V, 6hw3:H, 6hw3:V, 6hw4:H, 6hw4:V, 6hw5:H, 6hw5:V, 6hw6:H, 6hw6:V, 6hw7:H, 6hw7:V, 6hw8:H, 6hw8:V, 6hw9:H, 6hw9:V, 6hwa:V, 6hwb:H, 6hwb:V, 6hwc:V, 6hwd:H, 6hwd:V, 6hwe:H, 6hwe:V, 6hwf:H, 6hwf:V, 3hye:H, 3hye:V, 4inr:H, 4inr:V, 4int:H, 4int:V, 4inu:H, 4inu:V, 1jd2:H, 1jd2:O, 5jhr:V, 5jhs:H, 5jhs:V, 4jsu:H, 4jsu:V, 5l52:V, 5l54:V, 5l55:V, 5l5a:V, 5l5b:V, 5l5d:H, 5l5d:V, 5l5e:H, 5l5e:V, 5l5f:H, 5l5f:V, 5l5h:V, 5l5i:V, 5l5j:H, 5l5j:V, 5l5o:H, 5l5o:V, 5l5p:H, 5l5p:V, 5l5q:V, 5l5r:V, 5l5s:V, 5l5t:V, 5l5u:H, 5l5u:V, 5l5v:V, 5l5w:V, 5l5x:H, 5l5x:V, 5l5y:H, 5l5y:V, 5l5z:H, 5l5z:V, 5l60:V, 5l61:V, 5l62:V, 5l63:H, 5l63:V, 5l64:V, 5l65:H, 5l65:V, 5l66:H, 5l66:V, 5l67:V, 5l68:H, 5l68:V, 5l69:H, 5l69:V, 5l6a:H, 5l6a:V, 5l6b:H, 5l6b:V, 5l6c:V, 5lai:V, 5laj:V, 5ltt:V, 5m2b:V, 3mg0:H, 3mg0:V, 3mg4:H, 3mg6:H, 3mg7:H, 3mg8:H, 4nnn:H, 4nnn:V, 4nnw:H, 4nnw:V, 4no1:V, 4no6:V, 4no8:V, 4no9:H, 4no9:V, 7o2l:H, 7o2l:V, 3oeu:H, 3oev:H, 8ohz:H, 8ohz:V, 8oi1:H, 8oi1:V, 8olr:H, 8olr:V, 4q1s:H, 4q1s:V, 4qby:H, 4qby:V, 4qlq:H, 4qlq:V, 4qls:V, 4qlt:V, 4qlu:V, 4qlv:V, 4qux:V, 4qv0:V, 4qv1:V, 4qv3:V, 4qv4:V, 4qv5:V, 4qv6:V, 4qv7:V, 4qv8:V, 4qv9:V, 4qvl:H, 4qvl:V, 4qvm:H, 4qvm:V, 4qvn:H, 4qvn:V, 4qvp:H, 4qvp:V, 4qvq:H, 4qvq:V, 4qvv:H, 4qvv:V, 4qvw:H, 4qvw:V, 4qvy:H, 4qvy:V, 4qw0:H, 4qw0:V, 4qw1:H, 4qw1:V, 4qw3:H, 4qw3:V, 4qw4:H, 4qw4:V, 4qw5:H, 4qw5:V, 4qw6:H, 4qw6:V, 4qw7:H, 4qw7:V, 4qwf:H, 4qwf:V, 4qwg:H, 4qwg:V, 4qwi:H, 4qwi:V, 4qwj:H, 4qwj:V, 4qwk:H, 4qwk:V, 4qwl:H, 4qwl:V, 4qwr:H, 4qwr:V, 4qws:H, 4qws:V, 4qwu:H, 4qwu:V, 4qwx:H, 4qwx:V, 4qxj:H, 4qxj:V, 4qz0:H, 4qz0:V, 4qz1:H, 4qz1:V, 4qz2:H, 4qz2:V, 4qz3:H, 4qz3:V, 4qz4:H, 4qz4:V, 4qz5:H, 4qz5:V, 4qz6:H, 4qz6:V, 4qz7:H, 4qz7:V, 4qzw:H, 4qzw:V, 4qzx:H, 4qzx:V, 4qzz:H, 4qzz:V, 4r00:H, 4r00:V, 4r02:V, 4r17:V, 4r18:V, 8rhj:H, 8rhj:V, 8rhk:H, 8rhk:V, 8rhl:H, 8rhl:V, 4rur:V, 1ryp:I, 1ryp:W, 3sdi:H, 3sdi:V, 3sdk:H, 3un4:H, 3un4:V, 4y69:V, 4y6a:V, 4y6v:V, 4y6z:H, 4y6z:V, 4y70:H, 4y70:V, 4y74:H, 4y74:V, 4y75:V, 4y77:H, 4y77:V, 4y78:H, 4y78:V, 4y7w:H, 4y7w:V, 4y7x:V, 4y7y:H, 4y7y:V, 4y80:H, 4y80:V, 4y81:V, 4y82:H, 4y82:V, 4y84:H, 4y84:V, 4y8g:H, 4y8g:V, 4y8h:H, 4y8h:V, 4y8i:H, 4y8i:V, 4y8j:H, 4y8j:V, 4y8k:V, 4y8l:V, 4y8m:V, 4y8n:V, 4y8o:V, 4y8p:H, 4y8p:V, 4y8q:V, 4y8r:V, 4y8s:H, 4y8s:V, 4y8t:V, 4y8u:V, 4y9y:V, 4y9z:H, 4y9z:V, 4ya0:V, 4ya1:V, 4ya2:H, 4ya2:V, 4ya3:V, 4ya4:V, 4ya5:V, 4ya7:H, 4ya7:V, 4ya9:H, 4ya9:V, 4z1l:H, 4z1l:V, 2zcy:H, 2zcy:V, 6zou:H, 6zou:V, 6zp6:H, 6zp6:V, 6zp8:H, 6zp8:V
31 7mit:E 1438 59 0.1398 0.0090 0.2203 4.6 7mjo:E, 7mjp:E, 7mjq:E, 7y1l:A
32 1uyr:A 698 84 0.2581 0.0344 0.2857 5.1 5ctb:B, 3h0j:A, 3h0j:B, 3h0j:C, 3h0q:A, 3h0q:B, 3h0q:C, 3h0s:B, 3h0s:C, 1od4:C, 3pgq:B, 1uyr:B, 1uys:A, 1uys:B, 1uys:C, 1w2x:A, 1w2x:C, 1w2x:B
33 1bd2:D 190 33 0.1183 0.0579 0.3333 6.0
34 7y1n:A 1171 55 0.1290 0.0102 0.2182 6.5 7vlr:A, 7vls:A, 7vlt:A, 7vlu:A, 7y1k:A, 7y1m:A
35 4k6m:A 888 56 0.1828 0.0191 0.3036 6.6 4hdg:A, 4hdg:B, 4hdh:A, 4hdh:B, 4k6m:B, 4mtp:A, 4mtp:B
36 5csl:B 2072 84 0.2581 0.0116 0.2857 6.9 5ctb:A, 5ctb:C, 5ctc:A, 5ctc:B, 5ctc:C, 5cte:B, 5cte:C, 3h0s:A, 3k8x:A, 3k8x:B, 3k8x:C, 1od2:A, 1od2:B, 3pgq:A, 3pgq:C, 3tv5:A, 3tv5:B, 3tv5:C, 3tvu:A, 3tvu:B, 3tvu:C, 3tvw:A, 3tvw:B, 3tvw:C, 3tz3:A, 3tz3:B, 3tz3:C, 1w96:A, 1w96:B, 1w96:C, 4wyo:B, 4wyo:C, 4wz8:B, 4wz8:C
37 7znn:B 559 61 0.1613 0.0268 0.2459 7.0 7zn7:B
38 5csl:A 2050 84 0.2581 0.0117 0.2857 7.4
39 4mtp:C 585 56 0.1828 0.0291 0.3036 8.9
40 4mtp:D 546 56 0.1828 0.0311 0.3036 9.8
41 6hv9:3 558 26 0.0968 0.0161 0.3462 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218