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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LLSAAYVDSHQWEAREKEEYHLADLASLMDKAYERKLPVSSLSISRFVDNIASREDLDSAEYYLYKFRHSPNCWYLRDWT
IHSWIRQCLKYGAQDKALYTLVNKVQYGIFPDNFTFNLLMDYFIKKGNYKDALSVVFEIMMQEAFDVPSTQFLSLYVLYR
CLAEKTELTWEEERDFGASLLLSGLKQRNTVGLSSQLYGYALLGKVELQRGVRAVYHGMPLMWTPGYLDRALQVMERVAS
SPEDLKLGREVLDVLDGVLKVVTSPDGSANLVEQLDTEEPEQSKLPRYLERFQASRSKLQELNRVESESLLTLTTQLVKE
KLPACEAEDLATYEQKLREWHLERVQLIQREQEQREKAKQEYQAL

The query sequence (length=365) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7pnt:V 365 365 1.0000 1.0000 1.0000 0.0 7pnu:V, 7pnv:V, 7pnw:V
2 6gaw:Ae 388 379 0.8219 0.7732 0.7916 0.0 6gaz:Ae, 7nqh:Ae, 7nql:Ae, 7nsi:Ae, 7nsj:Ae, 8oin:AV, 8oip:AV, 6ydp:Ae, 6ydw:Ae
3 6neq:e 358 363 0.7918 0.8073 0.7961 0.0 3jd5:e, 6nf8:e
4 8k2a:Sc 385 375 0.7945 0.7532 0.7733 0.0 8any:AV, 8csq:V, 8csr:V, 8css:V, 8cst:V, 8csu:V, 7l08:AV, 8oir:AV, 8ois:AV, 7p2e:V, 7pnx:V, 7pny:V, 7pnz:V, 7po0:V, 7po1:V, 7po2:V, 7po3:V, 7qi4:AV, 7qi5:AV, 7qi6:AV, 8qrk:V, 8qrl:V, 8qrm:V, 8qrn:V, 6rw4:V, 6rw5:V, 6vlz:AV, 6vmi:AV, 8xt0:Sc, 8xt2:Sc, 6zm5:AV, 6zm6:AV
5 7og4:AV 349 346 0.7479 0.7822 0.7890 0.0 7a5f:V6, 7a5g:V6, 7a5i:V6, 7a5k:V6, 3j9m:AV, 6nu2:AV, 6nu3:AV, 6zs9:AV, 6zsa:AV, 6zsb:AV, 6zsc:AV, 6zsd:AV, 6zse:AV, 6zsg:AV
6 5i9h:A 368 118 0.0849 0.0842 0.2627 0.003 5i9d:A
7 5i9h:A 368 66 0.0630 0.0625 0.3485 0.006 5i9d:A
8 5i9h:A 368 116 0.0877 0.0870 0.2759 0.018 5i9d:A
9 5i9h:A 368 66 0.0603 0.0598 0.3333 0.039 5i9d:A
10 5i9h:A 368 66 0.0603 0.0598 0.3333 0.55 5i9d:A
11 5i9h:A 368 41 0.0438 0.0435 0.3902 0.74 5i9d:A
12 5i9h:A 368 46 0.0466 0.0462 0.3696 1.1 5i9d:A
13 5i9f:A 388 66 0.0630 0.0593 0.3485 0.007 5i9g:C
14 5i9f:A 388 66 0.0630 0.0593 0.3485 0.007 5i9g:C
15 5i9f:A 388 66 0.0630 0.0593 0.3485 0.007 5i9g:C
16 5i9f:A 388 66 0.0630 0.0593 0.3485 0.007 5i9g:C
17 5i9f:A 388 66 0.0630 0.0593 0.3485 0.007 5i9g:C
18 5i9f:A 388 66 0.0630 0.0593 0.3485 0.007 5i9g:C
19 4m59:A 687 61 0.0548 0.0291 0.3279 0.037 4m59:B, 4oe1:A, 4oe1:B
20 8y0w:CB 768 103 0.0822 0.0391 0.2913 0.11 8y0x:CB
21 4yer:A 285 80 0.0630 0.0807 0.2875 1.2 4yer:B
22 8q87:A 857 113 0.0822 0.0350 0.2655 2.2 6d9j:9, 6gz3:Ct, 6gz4:Ct, 6gz5:Ct, 3j7p:4, 7ls1:m, 7ls2:m, 6mtd:v, 6mte:v, 7oyc:v2, 4v6x:Az, 8xsx:CB, 6z6m:CB, 6z6n:CB
23 6nr2:A 859 106 0.0849 0.0361 0.2925 7.0 6nr2:B, 6nr2:C, 6nr2:D, 6nr3:A, 6nr3:B, 6nr3:C, 6nr3:D, 6o6a:A, 6o6a:B, 6o6a:C, 6o6a:D, 6o6r:A, 6o6r:B, 6o6r:C, 6o6r:D
24 8etp:D 441 112 0.0740 0.0612 0.2411 7.4 8eu3:D, 8euc:D, 8ev8:D, 8ev9:D, 8eva:D, 8evb:D, 8evc:D
25 4o27:A 325 79 0.0630 0.0708 0.2911 9.9 4fzd:A, 1upk:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218