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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LKWPRDLRPLAHHDLLYMGQISEEDRGDFNATLRNFLVPRVVGSQKHREVREFIVRSLKDLDWDVEEDCFDGQTPHGIKP
FCNVIATLNPSACHRLVLACHYDSLLHKEGTFIGATDSAVPCAQLLYLARSLNGKLQNQKTRGDGLTLQLVFFDGEEAFE
RWSSHDSLYGSRHLAQKWHEDRTSAERLESCLERSEIANQIDRMEVMVLLDLLGAENPRFYSYFGETQPVYRRLVNIESR
LNDAGLMELPRRRRRTNYFSNSSTVGFIEDDHIPFLKRSVPIVHIIPSPFPDVWHTLDDNEQNLHHPTISNLNKIFKAFV
SEYLQL

The query sequence (length=326) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7d21:A 328 326 0.9969 0.9909 0.9969 0.0 7d1h:A, 7d1n:A, 7d1y:A, 7d2d:A, 7d2i:A, 7d2j:A, 4mhn:A, 4mhy:A, 4mhz:A
2 4fai:B 305 302 0.4448 0.4754 0.4801 3.91e-89 4fai:A, 4fbe:A, 4fbe:B
3 3si1:A 323 299 0.4509 0.4551 0.4916 2.88e-88 3si2:A
4 6yi1:A 329 302 0.4571 0.4529 0.4934 1.28e-87 2afm:A, 2afm:B, 2afo:A, 2afo:B, 2afs:A, 2afs:B, 2afu:A, 2afu:B, 2afw:A, 2afw:B, 2afx:A, 2afx:B, 2afz:A, 2afz:B, 7cm0:A, 7cm0:B, 7cm0:C, 7cm0:D, 7coz:A, 7coz:B, 7coz:C, 7cp0:A, 7cp0:B, 7cp0:C, 7d8e:A, 7d8e:B, 7d8e:C, 9fxh:A, 9fxh:B, 9fxh:C, 9fxi:A, 9fxi:B, 9fxi:C, 9fxj:A, 9fxj:B, 9fxj:C, 6gbx:A, 6gbx:B, 6gbx:C, 8hy3:A, 3pbb:A, 3pbb:B, 3pbe:A, 3pbe:B, 3si0:A, 8xgb:B, 8xgt:B, 8xgt:A, 8xgt:C, 8xgt:D, 8xgt:E, 8xgt:F, 8xgt:G, 8xgt:H, 8xgt:I, 8xgt:J, 8xgt:K, 8xgt:L, 8xgy:B, 8xgy:E, 8xgy:A, 8xgy:D, 8xgy:C, 8xgy:K, 8xgy:F, 8xgy:I, 8xgy:G, 8xgy:H, 8xgy:J, 8xgy:L, 6yi1:B, 6yjy:A, 6yjy:B, 4yu9:A, 4yu9:B, 4yu9:C, 4ywy:A, 4ywy:B, 4ywy:C, 2zed:A, 2zed:B, 2zee:A, 2zee:B, 2zef:A, 2zef:B, 2zeg:A, 2zeg:B, 2zeh:A, 2zeh:B, 2zel:A, 2zel:B, 2zem:A, 2zem:B, 2zen:A, 2zen:B, 2zeo:A, 2zeo:B, 2zep:A, 2zep:B
5 4f9v:A 307 311 0.4233 0.4495 0.4437 3.47e-85 4f9u:B, 4f9u:A, 4f9v:B, 4fwu:A
6 3pb6:X 313 302 0.4325 0.4505 0.4669 1.62e-79 3pb4:X, 3pb7:X, 3pb8:X, 3pb9:X, 8xfv:X, 8xfv:A, 8xfv:B, 8xfv:C, 8xfv:D, 8xfv:E, 8xfv:F, 8xfv:G, 8xfv:H, 8xfv:I, 8xfv:J, 8xga:A, 8xga:B, 8xga:C, 8xga:D, 8xga:E, 8xga:F, 8xga:G, 8xga:H, 8xga:I, 8xga:J, 8xga:K
7 7d17:A 321 300 0.3712 0.3769 0.4033 2.53e-59
8 7d18:A 293 284 0.2454 0.2730 0.2817 1.16e-22
9 7cje:C 289 306 0.2423 0.2734 0.2582 1.40e-16 7cje:A, 7cjg:A, 7cjg:B, 6qql:A, 6qql:B
10 3tc8:A 293 292 0.2055 0.2287 0.2295 2.14e-09 3tc8:B
11 6qro:A 291 293 0.1779 0.1993 0.1980 1.26e-06 6qro:B, 6qro:C, 6qro:D
12 7d1d:A 294 294 0.2055 0.2279 0.2279 3.63e-05 7d1e:A, 4fuu:A
13 7d1b:A 302 308 0.1994 0.2152 0.2110 7.51e-05
14 2ek8:A 412 246 0.1748 0.1383 0.2317 0.002 2ek9:A, 5ib9:A
15 1h54:B 754 65 0.0583 0.0252 0.2923 0.27
16 8a98:SN 101 39 0.0460 0.1485 0.3846 1.4 8a3w:SN, 6az1:N, 8ovj:SN, 8rxh:SN, 8rxx:SN, 5t2a:AD

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218