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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LKVSKSPSLVRLKTRGESVCPISKTVDSFEVSVEYIPRGAVLAIEEFKKMVDSYRGREILHEELAVDLLEKVKAAVNPPY
VKVTVKSYYIGVEVEVVAESGGV

The query sequence (length=103) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5jyx:B 109 103 1.0000 0.9450 1.0000 2.50e-68 5jyx:A, 5jyx:E, 5jyx:C, 5jyx:J, 5jyx:D, 5jyx:H, 5jyx:F, 5jyx:O, 5jyx:G, 5jyx:L, 5jyx:I, 5jyx:K, 5jyx:M, 5jyx:N
2 1wm9:A 185 48 0.1553 0.0865 0.3333 0.001 1wm9:B, 1wm9:C, 1wm9:D, 1wm9:E, 1wuq:A, 1wuq:B, 1wuq:E, 1wuq:C, 1wuq:D, 1wur:A, 1wur:B, 1wur:E, 1wur:C, 1wur:D
3 4f8b:B 145 69 0.1553 0.1103 0.2319 0.11 4f8b:A, 4f8b:C, 4f8b:D, 4f8b:E, 4fgc:A, 4fgc:B, 4fgc:C, 4fgc:D, 4fgc:E, 5udg:A, 5udg:D, 5udg:E
4 4g5d:A 283 38 0.1359 0.0495 0.3684 0.49 4g5d:B
5 4gba:B 206 33 0.1262 0.0631 0.3939 0.78 4gba:A
6 4g06:A 68 22 0.0874 0.1324 0.4091 0.94 6jip:A, 6jiq:A, 5zkl:A
7 8x2i:A 2303 83 0.2524 0.0113 0.3133 1.2
8 8x2h:A 2363 83 0.2524 0.0110 0.3133 1.3 8jb5:A, 2vkd:A, 2vkd:B, 2vkd:C, 2vkh:A, 2vkh:B, 2vkh:C, 2vl8:A, 2vl8:B, 2vl8:C
9 2i89:A 90 36 0.1165 0.1333 0.3333 1.5 2i89:B, 2i89:C, 2i89:D, 1icc:A, 1icc:B, 1icc:D, 1lj0:A, 1lj0:B, 1lj0:C, 1lj0:D, 3mus:B
10 8jsg:A 167 25 0.0874 0.0539 0.3600 2.2 8jsh:A, 5me0:Z, 5me1:Z
11 1awp:A 86 36 0.1165 0.1395 0.3333 3.3 1awp:B, 1b5m:A, 1eue:A, 1eue:B, 4hil:A, 4hil:B, 1icc:C, 3mus:A
12 4rsm:A 315 54 0.1165 0.0381 0.2222 3.4 4rsm:B, 4rsm:C, 4rsm:D
13 7yb2:D 264 35 0.1359 0.0530 0.4000 3.8 8hfj:A, 8hfj:B, 8hfj:C, 8hfj:D, 8hfk:A, 8hfk:B, 8hfk:C, 8hfk:D, 7yb1:D, 7yb1:A, 7yb1:B, 7yb1:C, 7yb2:A, 7yb2:B, 7yb2:C
14 7ouj:AAA 540 31 0.1456 0.0278 0.4839 5.2
15 5ugh:B 365 59 0.2136 0.0603 0.3729 7.1 6fbn:B, 4ktt:A, 4ktt:C, 4ktv:C, 4ndn:C, 7rw5:D
16 8q6p:7 298 52 0.1650 0.0570 0.3269 7.4
17 2ohf:A 327 56 0.1650 0.0520 0.3036 8.3
18 8p4h:A 388 59 0.2136 0.0567 0.3729 8.6 5a19:A, 5a1g:A, 5a1i:A, 8axz:A, 7bhr:A, 7bhs:A, 7bht:A, 7bhu:A, 7bhv:A, 7bhw:A, 7bhx:A, 6fbn:A, 6fbo:A, 6fbp:A, 6fbp:B, 6fcb:A, 6fcd:A, 6g6r:A, 7kcc:A, 7kce:A, 7kcf:A, 7kda:A, 7kdb:A, 4ktt:B, 4ktt:D, 4ktv:A, 4ktv:B, 4ktv:D, 7l1a:A, 7lnh:A, 7lnh:B, 4ndn:A, 4ndn:B, 4ndn:D, 8oog:A, 2p02:A, 8p1t:AAA, 8p1v:AAA, 8p1w:AAA, 8p4h:B, 8p4h:C, 8p4h:D, 6p9v:A, 8qdy:A, 8qdz:A, 8qe0:A, 8qe1:A, 8qe2:A, 8qe3:A, 7rw5:A, 7rw5:B, 7rw5:C, 7rw7:A, 7rwg:A, 7rwh:A, 7rxv:A, 7rxw:A, 7rxx:A, 5ugh:A, 5ugh:C, 5ugh:D, 6wkb:A, 6wkb:B, 8xam:A, 8xam:B, 8xar:A, 8xb0:A
19 7mbm:A 339 29 0.0971 0.0295 0.3448 9.5 5ov3:B, 6pwv:A, 6pww:A, 6pwx:A, 6w5n:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218