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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LKLVDCIIEVHDARIPLSGRNPLFQETLGLKPHLLVLNKMDLADLTEQQKIMQHLEGEGLNVIFTNCVKDENVKQIIPMV
TELIGRSHRYHRKENLEYCIMVIGVPNVGKSSLINSLRFLLDTPGVLAPRIESVETGLKLALCGTVLDHLVGEETMADYL
LYTLNKHQRFGYVQHYGLGSACDNVERVLKSVAVKLGKTQKVKVLTGTGNVNIIQPNYPAAARDFLQTFRRGLLGSVMLD

The query sequence (length=240) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7o9k:C 255 243 0.9958 0.9373 0.9835 3.05e-174 7o9m:C
2 7pd3:z 311 275 1.0000 0.7717 0.8727 3.81e-169 8pk0:z, 8qsj:z
3 1puj:A 261 214 0.2917 0.2682 0.3271 1.58e-35 6ppk:W
4 6g0z:A 290 204 0.2667 0.2207 0.3137 1.92e-26 6g0z:B, 6g12:A, 6g12:B, 6g14:B, 6g14:A, 6g15:A, 6g15:B
5 6yxx:EM 308 167 0.2208 0.1721 0.3174 6.41e-19
6 7am2:BT 300 290 0.3167 0.2533 0.2621 1.51e-16
7 6yxy:EM 330 287 0.3083 0.2242 0.2578 9.43e-16
8 3cnl:A 233 162 0.2000 0.2060 0.2963 1.63e-12 3cnn:A, 3cno:A
9 8fkt:NB 387 120 0.1708 0.1059 0.3417 1.76e-09 8fkp:NB, 8fku:NB, 8fkv:NB, 8fkw:NB, 8fkx:NB, 8fky:NB, 8fkz:NB, 8fl0:NB, 8ink:u, 8ipd:u, 8ipx:u, 8ipy:u
10 8fl2:NC 511 224 0.2417 0.1135 0.2589 9.04e-08 8fkz:NC, 8fl0:NC, 8fl3:NC, 8fl4:NC, 8idt:A, 8idy:A, 8ie3:A, 8ine:A, 8inf:A, 8ink:w, 8ipd:w, 8ipx:w, 8ipy:w, 8ir1:w, 8ir3:w
11 6n8j:m 378 165 0.1875 0.1190 0.2727 6.71e-07
12 7btb:m 469 165 0.1875 0.0959 0.2727 9.98e-07 7bt6:m, 6ft6:m, 3jct:m, 6m62:m, 7oh3:m, 7ohq:m, 7oht:m, 7ug6:m, 7uoo:m, 7uqb:m, 7uqz:m, 7uui:m, 7v08:m, 6ylg:m, 6ylh:m
13 8pv1:Cd 462 262 0.2792 0.1450 0.2557 6.42e-06 8pv2:Cd, 8pv3:Cd, 8pv4:Cd, 8pv5:Cd, 8pv6:Cd, 8pv7:Cd, 8pv8:Cd, 8pvk:Cd, 8pvl:Cd
14 6qtz:o 325 119 0.1417 0.1046 0.2857 1.96e-05 6qik:o, 6ri5:o, 6rzz:o, 6s05:o
15 2qa5:B 234 63 0.1250 0.1282 0.4762 3.97e-04 2qa5:A, 2qag:A, 2qnr:A
16 6n8n:W 377 129 0.1500 0.0955 0.2791 0.004 6n8o:W
17 3ftq:B 252 59 0.1083 0.1032 0.4407 0.010 3ftq:C, 3ftq:D, 2qnr:B, 6upa:A
18 2qag:C 224 55 0.0958 0.1027 0.4182 0.010
19 8i9w:CL 397 161 0.1875 0.1134 0.2795 0.024 8i9t:CL, 8i9v:CL, 8i9x:CL, 8i9y:CL, 8i9z:CL, 8ia0:CL, 8pv1:CL, 8pv2:CL, 8pv3:CL, 8pv4:CL, 8pv5:CL, 8pv6:CL, 8pv7:CL, 8pv8:CL, 8pvk:CL, 8pvl:CL
20 5t62:W 306 115 0.1417 0.1111 0.2957 0.045
21 9bht:C 282 50 0.0875 0.0745 0.4200 0.055 9bht:D, 9bhw:A, 9bhw:D
22 7of1:m 229 61 0.0792 0.0830 0.3115 0.083
23 2e87:A 356 93 0.1208 0.0815 0.3118 0.10
24 5oxf:B 591 48 0.0792 0.0321 0.3958 0.11
25 5oxf:A 703 48 0.0792 0.0270 0.3958 0.11
26 5cyp:D 227 80 0.0833 0.0881 0.2500 0.11
27 6upq:A 270 69 0.1125 0.1000 0.3913 0.13 3ftq:A, 7m6j:F, 6upr:A
28 7m6j:D 273 40 0.0750 0.0659 0.4500 0.16 7m6j:C, 6n0b:C, 6n0b:A, 6n0b:B, 6n0b:D, 6n12:A, 6n12:B, 3t5d:A, 3t5d:C, 6uqq:A, 6uqq:B
29 5cyp:A 248 58 0.0833 0.0806 0.3448 0.16 5cyp:B, 5cyp:C
30 6vil:D 156 108 0.1083 0.1667 0.2407 0.19 6vil:C, 6vil:B, 6vil:E, 6vil:G
31 3geh:A 442 71 0.0917 0.0498 0.3099 0.27
32 8ir1:4 620 76 0.1250 0.0484 0.3947 0.27 8fkt:SR, 8fku:SR, 8fkv:SR, 8fkw:SR, 8fkx:SR, 8fky:SR, 8fkz:SR, 8fl0:SR, 8fl2:SR, 8fl3:SR, 8fl6:SR, 8fl7:SR, 8fl9:SR, 8fla:SR, 8flb:SR, 8flc:SR, 8fld:SR, 8fle:SR, 8flf:SR, 8idt:4, 8idy:4, 8ie3:4, 8ine:4, 8inf:4, 8ink:4, 8ipd:4, 8ipx:4, 8ipy:4, 8ir3:4, 6lss:4, 6lu8:4
33 3a1s:A 255 41 0.0667 0.0627 0.3902 0.27 3a1s:B, 3a1t:A, 3a1u:A, 3a1u:B
34 8fl4:SR 593 76 0.1250 0.0506 0.3947 0.28 8fkr:SR, 8fks:SR
35 7w46:B 402 125 0.1250 0.0746 0.2400 0.31
36 2wjg:A 170 39 0.0667 0.0941 0.4103 0.36 2wjg:B, 2wjh:A, 2wjh:B, 2wji:A, 2wji:B, 2wjj:A, 2wjj:B
37 7o9k:G 337 55 0.0667 0.0475 0.2909 0.36 7of5:x, 7of7:x
38 5m7h:A 420 27 0.0542 0.0310 0.4815 0.36 4dcs:A, 4dct:A, 4dcu:A, 2hjg:A, 5mbs:A, 5x4b:A, 5x4b:B
39 5m7h:A 420 54 0.0667 0.0381 0.2963 1.7 4dcs:A, 4dct:A, 4dcu:A, 2hjg:A, 5mbs:A, 5x4b:A, 5x4b:B
40 6lsr:1 247 104 0.1083 0.1053 0.2500 0.40
41 7oi6:y 331 62 0.0875 0.0634 0.3387 0.41 8pk0:t
42 7odt:t 316 55 0.0667 0.0506 0.2909 0.45
43 9bht:A 220 41 0.0708 0.0773 0.4146 0.45 9bht:F
44 5dn8:A 405 115 0.1458 0.0864 0.3043 0.50
45 5dn8:A 405 37 0.0667 0.0395 0.4324 0.91
46 2pzi:A 654 93 0.1083 0.0398 0.2796 0.71 2pzi:B, 7q52:AAA, 4y0x:A, 4y12:A
47 7m6j:A 234 67 0.1083 0.1111 0.3881 0.74
48 3tw4:A 218 27 0.0625 0.0688 0.5556 0.80 3tw4:B
49 8dkt:A 264 69 0.1042 0.0947 0.3623 0.81
50 5uz4:Z 323 98 0.1250 0.0929 0.3061 0.81 4a2i:V, 7boi:W, 7nar:W, 5no2:Z, 5no3:Z, 5no4:Z, 2rcn:A, 2ykr:W
51 3ieu:A 293 22 0.0542 0.0444 0.5909 0.95 3ieu:B
52 5trd:A 219 39 0.0792 0.0868 0.4872 1.1 5trd:B
53 2dyk:A 150 20 0.0458 0.0733 0.5500 1.2 2dyk:B
54 7bl2:9P1 338 47 0.0750 0.0533 0.3830 1.2 7bl3:9P, 7bl4:9, 7bl5:9, 7bl6:9, 4csu:9, 5m04:A
55 8sgd:A 291 29 0.0583 0.0481 0.4828 1.3 8fwp:A, 8pfh:A, 8sgd:C
56 2dby:A 355 19 0.0417 0.0282 0.5263 1.5
57 4jyb:A 323 69 0.1000 0.0743 0.3478 1.7 8dpb:A, 8dpb:B, 4jyb:B, 4jyc:D, 4lc1:A, 4lc1:B, 2qm7:A, 2qm7:B
58 7apd:C 287 19 0.0500 0.0418 0.6316 1.7 5a9k:A, 5a9k:B, 5a9k:C, 7apd:D, 7apd:E, 7apd:F, 7apd:A, 2gxa:B, 2gxa:C, 2gxa:D, 2gxa:E, 2gxa:F, 2gxa:G, 2gxa:H, 2gxa:I, 2gxa:J, 2gxa:K, 2gxa:L, 2gxa:A, 2v9p:A, 2v9p:B, 2v9p:C, 2v9p:H, 2v9p:I
59 4l0e:A 440 85 0.1125 0.0614 0.3176 1.7 4l0f:A, 4pwv:A, 4pxh:A, 4pxh:C, 4pxh:E
60 8csq:a 263 89 0.1042 0.0951 0.2809 2.0
61 1wf3:A 296 40 0.0583 0.0473 0.3500 2.2
62 7y9i:A 362 18 0.0458 0.0304 0.6111 2.4
63 5cyo:A 272 24 0.0500 0.0441 0.5000 2.5 5cyo:B, 4yqf:B, 4yqf:A
64 1xzq:A 449 169 0.1625 0.0869 0.2308 3.0 1xzq:B
65 1xzq:A 449 31 0.0542 0.0290 0.4194 5.1 1xzq:B
66 7ok0:A 880 109 0.1083 0.0295 0.2385 3.0 7oq4:A, 7oqy:A
67 6zj3:Lo 58 28 0.0500 0.2069 0.4286 3.0
68 2dhr:A 458 163 0.1375 0.0721 0.2025 3.2 2dhr:B, 2dhr:C, 2dhr:D, 2dhr:E, 2dhr:F, 4eiw:A, 4eiw:B, 4eiw:C, 4eiw:D, 4eiw:E, 4eiw:F, 1iy0:A, 1iy1:A
69 6xrs:B 392 19 0.0458 0.0281 0.5789 3.4 6xrs:A, 6xrs:D, 6xrs:C
70 6xrs:B 392 22 0.0500 0.0306 0.5455 5.6 6xrs:A, 6xrs:D, 6xrs:C
71 1mky:A 407 19 0.0417 0.0246 0.5263 3.6
72 7mfm:I 490 85 0.0958 0.0469 0.2706 3.6 7mfm:J, 7mft:I
73 8kie:y 363 16 0.0417 0.0275 0.6250 4.1
74 3aq0:C 327 69 0.1000 0.0734 0.3478 4.3 3aq0:A, 3aq0:B, 3aq0:E, 3aq0:F, 3aq0:G, 3aq0:H
75 9bhw:B 299 25 0.0375 0.0301 0.3600 5.2 9bhw:C
76 8x5i:D 557 28 0.0458 0.0197 0.3929 5.9 8x5i:B
77 8x5i:A 477 28 0.0458 0.0231 0.3929 6.3 8x5i:C, 8x5n:A, 8x5n:D, 8x5n:B, 8x5n:C
78 6d71:A 172 35 0.0625 0.0872 0.4286 6.4 6d71:B
79 1nks:C 194 26 0.0417 0.0515 0.3846 6.4 1nks:D, 1nks:F
80 8wy4:A 451 28 0.0458 0.0244 0.3929 6.4 8wy4:B, 8wy4:D, 8wy4:C, 8wy5:A, 8wy5:B, 8wy5:C, 8wy5:D, 8x51:A, 8x51:B
81 2gj8:D 172 18 0.0417 0.0581 0.5556 7.4 2gj8:A, 2gj8:B, 2gj8:C, 2gj9:A, 2gj9:B, 2gj9:C, 2gj9:D, 2gja:A, 2gja:B
82 5m1j:A6 539 49 0.0583 0.0260 0.2857 7.6
83 8kab:h 430 31 0.0458 0.0256 0.3548 8.0
84 8pv1:CH 627 66 0.0792 0.0303 0.2879 8.1 8i9r:CH, 8i9t:CH, 8i9v:CH, 8i9w:CH, 8i9x:CH, 8i9y:CH, 8i9z:CH, 8ia0:CH, 8pv2:CH, 8pv3:CH, 8pv4:CH, 8pv5:CH, 8pv6:CH, 8pv7:CH, 8pv8:CH, 8pvk:CH, 8pvl:CH
85 3iev:A 302 18 0.0417 0.0331 0.5556 8.2 7c1o:A, 3r9w:A, 3r9x:A
86 8oun:A 181 32 0.0458 0.0608 0.3438 8.3 8oum:A, 8oum:B, 8oum:C, 8oum:D, 8oum:E, 8oun:B
87 3wy9:A 416 71 0.0708 0.0409 0.2394 8.7 3wy9:B, 3wya:A
88 4ap6:A 389 132 0.1167 0.0720 0.2121 8.9 4ap6:B, 4ap6:C, 4ap6:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218