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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LKKDVFVPDDKEEFVKATILSREGGKVTAETEHGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYASW
MIYTYSGLFCVTINPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVI
QYFAVIAAIGGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDY
HIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTTEEKNSMYKLTGAIMHFGNMK
FKLKEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVVYAKGALAKAVYERMFNWMVTRINAT
LETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEK
PMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSSNFQKPRNIKPEAHFSLIHYAGTVDYNIIGWLQKNKDPLNETVVDL
YKKSSLKMLSSLFANYQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVIDNPLVMHQLRCNGVLEGIRICRKG
FPNRILYGDFRQRYRILNPAADSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERL

The query sequence (length=706) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8act:A 873 718 0.9688 0.7835 0.9526 0.0 8act:B, 9f6c:B, 8qyp:A, 8qyq:A, 8qyq:B, 8qyr:B
2 4pa0:A 974 727 0.9603 0.6961 0.9326 0.0 4db1:A, 4db1:B, 8efe:A, 8efh:A, 9f6c:A, 6fsa:A, 6fsa:B, 5n69:A, 5n69:B, 5n6a:A, 8qyu:A
3 4pa0:B 920 718 0.9504 0.7293 0.9345 0.0 8qyu:B
4 6ysy:A 767 715 0.8300 0.7640 0.8196 0.0
5 1qvi:A 806 722 0.6615 0.5794 0.6468 0.0 1kk7:A, 1kk8:A, 2otg:A, 1s5g:A
6 3i5f:A 810 721 0.6686 0.5827 0.6546 0.0
7 1kwo:A 780 712 0.6501 0.5885 0.6447 0.0 1b7t:A, 1dfl:A, 1kqm:A, 1l2o:A
8 1dfl:B 766 712 0.6459 0.5953 0.6404 0.0
9 5w1a:A 786 732 0.6459 0.5802 0.6230 0.0 8exw:A, 5w1a:C
10 6qdj:A 758 730 0.6062 0.5646 0.5863 0.0
11 7mf3:B 896 738 0.5397 0.4252 0.5163 0.0 1br1:A, 1br1:C, 1br1:E, 1br1:G, 1br4:A, 1br4:C, 1br4:E, 1br4:G, 7mf3:A, 6z47:A, 6z47:B
12 5t45:A 708 716 0.5340 0.5325 0.5265 0.0 5m05:A
13 5i4e:A 959 704 0.5127 0.3775 0.5142 0.0
14 1br2:A 673 711 0.5198 0.5453 0.5162 0.0 1br2:B, 1br2:C, 1br2:D, 1br2:E, 1br2:F
15 1jwy:A 1039 724 0.5071 0.3446 0.4945 0.0 4ae3:A, 2aka:A, 7b19:A, 7b1a:A, 3bz7:A, 3bz8:A, 3bz9:A, 1d0x:A, 1d0y:A, 1d0z:A, 1d1a:A, 1d1b:A, 1d1c:A, 1fmw:A, 2jhr:A, 2jj9:A, 1jx2:A, 1lvk:A, 3mjx:A, 3mkd:A, 1mma:A, 1mmd:A, 1mmg:A, 1mmn:A, 1mne:A, 3mnq:A, 3myh:X, 3myk:X, 3myl:X, 4pjk:A, 1vom:A, 1w9i:A, 1w9j:A, 1w9k:A, 1w9l:A, 2x9h:A, 2xel:A, 2xo8:A, 2y8i:X, 1yv3:A, 6z2s:A, 6z7t:A, 6z7t:B, 6z7u:A
16 1g8x:A 1009 729 0.5057 0.3538 0.4897 0.0 1g8x:B
17 1mnd:A 641 646 0.4263 0.4696 0.4659 0.0
18 1w7j:A 752 721 0.4178 0.3923 0.4092 0.0 7pm5:A, 7pm6:A, 7pm6:D, 7pm7:A, 7pm8:A, 7pm9:A, 7pma:A, 7pmb:A, 7pmc:A, 7pmd:A, 7pme:A, 7pme:D, 7pmf:A, 7pmg:A, 7pmh:A, 7pmi:A, 7pmj:A, 7pml:A, 1w7i:A
19 5hmp:B 712 712 0.4164 0.4129 0.4129 2.97e-174 5hmp:A, 4zg4:B, 4zg4:E
20 7dhw:A 726 727 0.4023 0.3912 0.3906 5.94e-174
21 4byf:A 698 662 0.3584 0.3625 0.3822 3.87e-150 4byf:C
22 7udu:D 701 673 0.3711 0.3738 0.3893 7.02e-150 7rb8:D
23 5i0i:A 784 739 0.3754 0.3380 0.3586 2.55e-148 5i0h:A, 5i0h:B, 5i0i:B
24 1lkx:C 679 684 0.3654 0.3800 0.3772 2.64e-146 1lkx:A, 1lkx:B, 1lkx:D
25 4l79:A 734 687 0.3697 0.3556 0.3799 1.45e-143 6c1d:P, 6c1g:P
26 2vb6:A 724 706 0.3555 0.3467 0.3555 4.44e-140
27 4dbq:A 744 709 0.3598 0.3414 0.3583 4.36e-138 4pjj:A, 2vas:A
28 6ui4:A 692 688 0.3598 0.3671 0.3692 8.13e-137
29 4anj:A 995 734 0.3654 0.2593 0.3515 5.74e-134 1jbz:A
30 8w41:A 1162 741 0.3626 0.2203 0.3455 2.47e-133 4dbr:A, 4e7s:A, 4e7s:B, 4e7z:A, 4e7z:B, 5o2l:A, 4pfo:A, 4pfp:A, 4pfp:C, 4pjl:A, 4pjm:A, 4pjn:A, 4pk4:A, 2v26:A
31 6due:A 737 657 0.2946 0.2822 0.3166 3.52e-100
32 6ycx:B 817 692 0.3074 0.2656 0.3136 2.47e-96 8a12:A, 8cdm:A, 8cdq:A, 6i7e:A, 6ycx:A, 6ycy:A, 6ycz:A
33 6d50:B 840 49 0.0227 0.0190 0.3265 0.31 6d50:A, 6nzg:A, 6nzg:B, 5uj6:A, 5uj6:B
34 5n9d:B 866 97 0.0382 0.0312 0.2784 1.6 5n8r:A, 5n8r:B, 5n8s:A, 5n8s:B, 5n8u:A, 5n8u:B, 5n8z:A, 5n8z:B, 5n90:A, 5n90:B, 5n94:A, 5n94:B, 5n96:A, 5n96:B, 5n98:A, 5n98:B, 5n9a:A, 5n9a:B, 5n9d:A, 5n9e:A, 5n9e:B, 5n9f:A, 5n9f:B
35 8fhk:C 574 40 0.0198 0.0244 0.3500 2.5 8fmv:C, 8fpf:C, 7m33:C, 8szc:C, 8t1p:C
36 8ro1:DX 682 63 0.0312 0.0323 0.3492 2.7
37 5dhh:B 387 87 0.0297 0.0543 0.2414 3.0 5dhg:A, 5dhg:B, 5dhh:A, 4ea3:A, 4ea3:B, 8f7x:R
38 6i3p:C 630 52 0.0255 0.0286 0.3462 4.4 6i3p:A, 6i3p:B, 6i3p:D, 6qic:A, 6qic:B, 6qic:C, 6qic:D
39 4wbq:A 174 58 0.0241 0.0977 0.2931 6.4 4wbq:B
40 8jg7:E 409 53 0.0255 0.0440 0.3396 6.6 8jg7:A, 8jg7:C, 8jg7:D
41 7b9v:Q 624 19 0.0156 0.0176 0.5789 7.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218