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●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
LKFLVVDDGGTGRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRADGAMSALPVLM
VTAEAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFEKLGM

The query sequence (length=124) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 3rvr:B 131 124 0.9597 0.9084 0.9597 2.68e-82 1a0o:A, 1a0o:C, 1a0o:E, 1a0o:G, 2b1j:A, 2b1j:B, 1bdj:A, 1chn:A, 2che:A, 3chy:A, 5chy:A, 5d2c:A, 5d2c:B, 5dgc:A, 5dgc:B, 5dkf:A, 5dkf:B, 1f4v:A, 1f4v:B, 1f4v:C, 3f7n:A, 3f7n:B, 1ffg:A, 1ffg:C, 1ffs:A, 1ffs:C, 1ffw:A, 1ffw:C, 3fft:A, 3fft:B, 3ffw:A, 3ffw:B, 3ffx:A, 3ffx:B, 3fgz:A, 3fgz:B, 2fka:A, 2flk:A, 2flw:A, 2fmf:A, 2fmh:A, 2fmi:A, 2fmk:A, 1fqw:A, 1fqw:B, 1kmi:Y, 1mih:A, 1mih:B, 3myy:A, 3myy:B, 3olv:A, 3olv:B, 3olw:A, 3olw:B, 3olx:A, 3olx:B, 3oly:A, 3oly:B, 3oo0:A, 3oo0:B, 3oo1:A, 3oo1:B, 2pl9:A, 2pl9:B, 2pl9:C, 2pmc:A, 2pmc:B, 3rvj:A, 3rvj:B, 3rvk:A, 3rvl:A, 3rvl:B, 3rvm:A, 3rvn:A, 3rvn:B, 3rvo:A, 3rvp:A, 3rvp:B, 3rvq:A, 3rvr:A, 3rvs:A, 3rvs:B, 6tg7:A, 1u8t:A, 1u8t:B, 1ymv:A, 1zdm:A, 1zdm:B
2 4hnq:A 124 120 0.6290 0.6290 0.6500 7.85e-55 4hns:A, 4jp1:A, 4lx8:A, 3to5:A
3 3gwg:A 123 120 0.4516 0.4553 0.4667 2.75e-36 3h1e:A, 3h1g:A
4 4h60:A 120 118 0.3629 0.3750 0.3814 1.74e-22
5 2iyn:B 124 122 0.2823 0.2823 0.2869 3.85e-17 2iyn:A, 2iyn:C, 1zes:A, 1zes:B, 1zes:C
6 3m6m:D 118 117 0.3387 0.3559 0.3590 1.51e-15 3m6m:E, 3m6m:F
7 7od9:B 129 123 0.3065 0.2946 0.3089 3.34e-14 6ekg:Y, 6ekh:Y, 7od9:A
8 6ont:A 121 120 0.2903 0.2975 0.3000 4.61e-14
9 2a9r:A 118 121 0.3226 0.3390 0.3306 1.42e-13 2a9o:A, 2a9p:A, 6eb7:A, 6ebr:A, 1nxp:A, 1nxt:A
10 6rgz:D 122 118 0.3145 0.3197 0.3305 1.59e-13 6azr:B, 6azr:D, 3gl9:A, 3gl9:B, 3gl9:C, 3gl9:D, 4ja2:A, 4jas:B, 4jav:C, 4jav:D, 6rfv:C, 6rfv:D, 6rgy:C, 6rgy:D, 6rgz:C, 6rh0:C, 6rh0:D, 5uht:B, 5uht:D
11 2r25:B 133 117 0.2903 0.2707 0.3077 1.89e-13
12 7p8e:A 126 121 0.3468 0.3413 0.3554 3.67e-13
13 6is1:B 121 120 0.2742 0.2810 0.2833 4.63e-13 6is1:A, 6is1:C, 6is1:D, 6is1:E, 6is1:F, 6is1:G, 6is1:H, 6is2:A, 6is2:B, 6is2:C, 6is2:D, 6is3:C
14 1mvo:A 121 120 0.2742 0.2810 0.2833 2.23e-12
15 7w9h:B 122 110 0.3306 0.3361 0.3727 2.86e-12 7w9h:A
16 7cfw:A 123 116 0.2581 0.2602 0.2759 4.72e-12 7c1j:A
17 1mav:A 117 120 0.2419 0.2564 0.2500 6.85e-12 1mb0:A, 1mb3:A
18 6ifh:A 119 118 0.3065 0.3193 0.3220 7.16e-12
19 6c40:D 118 120 0.2742 0.2881 0.2833 8.13e-12 6c40:B, 4iga:A, 3tmy:A, 3tmy:B, 4tmy:A, 4tmy:B
20 1j56:A 124 102 0.2984 0.2984 0.3627 1.07e-11 1krx:A
21 6zxb:A 293 121 0.2903 0.1229 0.2975 2.75e-11 6zxb:B, 6zxc:A, 6zxc:B, 6zxc:C, 6zxc:D, 6zxm:A, 6zxm:B, 6zxm:C, 6zxm:D, 6zxm:E, 6zxm:F
22 6ww6:B 192 110 0.2823 0.1823 0.3182 3.19e-11 6wsh:A, 6wsh:B, 6ww6:A
23 5ed4:E 224 122 0.3387 0.1875 0.3443 3.72e-11 5ed4:A, 5ed4:B, 5ed4:F, 2pmu:E
24 8phx:C 130 120 0.2500 0.2385 0.2583 4.45e-11 8phx:A, 8phx:B, 8phx:D
25 6xvu:D 141 131 0.3145 0.2766 0.2977 4.46e-11 6xvu:A, 6xvu:C, 6xvu:B
26 5brj:A 140 89 0.2258 0.2000 0.3146 4.97e-11
27 2pl1:A 121 121 0.2661 0.2727 0.2727 5.55e-11
28 7qz2:B 132 123 0.3226 0.3030 0.3252 7.16e-11 7qz2:A
29 8pdc:A 122 122 0.2984 0.3033 0.3033 7.40e-11
30 4euk:A 136 134 0.2742 0.2500 0.2537 8.97e-11
31 1l5y:B 151 118 0.3145 0.2583 0.3305 1.14e-10 1l5y:A
32 2gwr:A 225 105 0.2500 0.1378 0.2952 1.16e-10 3nhz:B, 3nhz:C, 3nhz:D
33 7p8d:A 139 128 0.3468 0.3094 0.3359 1.17e-10 7p8d:B
34 3cg4:A 126 111 0.2581 0.2540 0.2883 3.55e-10
35 4kny:B 226 113 0.2984 0.1637 0.3274 5.23e-10 4kfc:A, 4kfc:B, 4kny:A, 1zh2:A, 1zh2:B, 1zh4:A, 1zh4:B
36 2oqr:A 226 105 0.2661 0.1460 0.3143 5.79e-10
37 8uvx:A 222 106 0.2500 0.1396 0.2925 5.83e-10 8uvk:A, 8uvk:B, 8uvx:B
38 5xt2:B 204 104 0.2903 0.1765 0.3462 6.46e-10 5xt2:A, 5xt2:C, 5xt2:D, 5xt2:E
39 5ic5:A 166 89 0.2016 0.1506 0.2809 7.37e-10
40 1yio:A 198 110 0.2903 0.1818 0.3273 8.24e-10 1zn2:A
41 1s8n:A 190 110 0.2661 0.1737 0.3000 1.02e-09
42 4qpj:D 121 123 0.2742 0.2810 0.2764 1.16e-09
43 4yn8:A 201 121 0.2823 0.1741 0.2893 1.87e-09
44 1ys6:B 227 104 0.2581 0.1410 0.3077 1.96e-09 1ys6:A, 1ys7:A, 1ys7:B
45 3a10:A 116 118 0.3065 0.3276 0.3220 2.76e-09 3a0u:A
46 8t85:A 335 104 0.2903 0.1075 0.3462 5.69e-09 7lcm:A
47 6ob8:A 307 104 0.2661 0.1075 0.3173 8.97e-09 6oap:A, 6oap:B, 6oaq:A, 6oaq:B, 6ob8:B
48 8svz:A 120 110 0.2661 0.2750 0.3000 1.59e-08 8svz:B
49 1qmp:A 126 91 0.2339 0.2302 0.3187 1.61e-08 1qmp:B, 1qmp:C, 1qmp:D
50 8jo2:H 219 93 0.2177 0.1233 0.2903 3.72e-08 8jo2:I, 4s04:A, 4s04:B, 4s04:E, 4s04:F, 4s05:A, 4s05:B, 3w9s:A, 3w9s:B
51 3luf:B 246 124 0.2823 0.1423 0.2823 4.08e-08 3luf:A, 3mf4:A, 3mf4:B
52 3luf:B 246 104 0.2258 0.1138 0.2692 0.003 3luf:A, 3mf4:A, 3mf4:B
53 6qrj:A 463 116 0.2742 0.0734 0.2931 1.09e-07 6qrl:A, 6qrl:B
54 6qrj:A 463 43 0.1210 0.0324 0.3488 2.8 6qrl:A, 6qrl:B
55 3nnn:A 119 121 0.2823 0.2941 0.2893 1.52e-07 3nnn:B
56 3hzh:A 134 120 0.2661 0.2463 0.2750 1.62e-07
57 1jlk:A 141 110 0.2258 0.1986 0.2545 1.90e-07
58 3hdg:A 124 116 0.2661 0.2661 0.2845 2.24e-07 3hdg:B, 3hdg:D, 3hdg:E
59 3nns:A 117 120 0.2742 0.2906 0.2833 2.99e-07 3nns:B
60 1k68:A 140 109 0.2339 0.2071 0.2661 3.05e-07 1k68:B
61 5lwk:A 122 116 0.2581 0.2623 0.2759 3.44e-07 5lwk:B
62 1srr:C 121 116 0.2419 0.2479 0.2586 7.81e-07 1f51:E, 2ftk:E, 2ftk:F, 2ftk:G, 2ftk:H, 1pey:A, 1pey:B, 1pey:C, 3q15:C, 1srr:A
63 5n2n:A 149 80 0.1935 0.1611 0.3000 1.37e-06 3mmn:A
64 2v0n:A 459 105 0.2419 0.0654 0.2857 2.03e-06 2v0n:B, 1w25:A, 1w25:B, 2wb4:A, 2wb4:B
65 2v0n:A 459 121 0.2258 0.0610 0.2314 0.022 2v0n:B, 1w25:A, 1w25:B, 2wb4:A, 2wb4:B
66 3bre:B 328 104 0.2419 0.0915 0.2885 2.35e-06 3bre:A
67 1xhf:B 122 110 0.2339 0.2377 0.2636 2.50e-06 1xhf:A
68 7cci:B 134 118 0.2581 0.2388 0.2712 2.66e-06 7cci:A, 5xjp:A
69 6br7:B 125 120 0.2419 0.2400 0.2500 3.20e-06 6br7:A, 6vbf:A, 6vbf:B
70 5wq0:D 129 67 0.1694 0.1628 0.3134 3.30e-06 5wq0:B, 5wq0:A, 5wq0:C, 5wq0:E, 5wq0:F, 5wq0:G
71 5hev:F 210 109 0.2823 0.1667 0.3211 4.68e-06 5hev:A, 5hev:B, 5hev:C
72 6swl:A 133 117 0.2581 0.2406 0.2735 6.51e-06 6swl:B
73 4zmr:A 207 121 0.2823 0.1691 0.2893 8.52e-06 4e7o:A, 4e7o:B, 4e7p:A, 4e7p:B, 4zmr:B, 4zms:A, 4zms:B
74 7lza:A 219 106 0.2581 0.1461 0.3019 1.53e-05 7lz9:A
75 4uhk:A 130 120 0.2903 0.2769 0.3000 2.22e-05 4uhj:A, 4uhj:B, 4uhj:C, 4uhk:B, 4uhk:C, 4uhs:B, 4uhs:C
76 8tef:A 516 78 0.1855 0.0446 0.2949 2.83e-05 8p6f:A, 8p6f:B, 8ted:A, 8ted:B, 8tef:B, 8tef:C, 8tef:D, 8tff:A, 8tff:B, 8tfm:A, 8tfm:B, 8thp:A, 8thp:B
77 4b09:A 218 87 0.1774 0.1009 0.2529 3.19e-05 4b09:B, 4b09:C, 4b09:D, 4b09:E, 4b09:F, 4b09:G, 4b09:I, 4b09:K
78 1dck:B 125 77 0.1774 0.1760 0.2857 3.50e-05 1dck:A, 1dcm:B
79 7pv7:C 514 104 0.2419 0.0584 0.2885 8.01e-05 7pv7:D, 7pv7:B, 7pv7:A, 7pva:A, 7pva:B, 7pva:C, 7pva:D, 7pvk:A, 7pvk:D, 7pvk:B, 7pvk:C
80 6oec:L 162 112 0.2742 0.2099 0.3036 9.59e-05 6oec:B, 6oec:C, 6oec:E, 6oec:F, 6oec:G, 6oec:I
81 5m7o:A 448 111 0.2823 0.0781 0.3153 2.18e-04 4d6y:A, 4d6y:B, 5m7n:A, 5m7o:B, 5m7p:A, 5m7p:B
82 4if4:A 208 118 0.2581 0.1538 0.2712 4.24e-04 4if4:B, 4if4:C, 4if4:D, 7ve5:B, 7ve5:A, 7ve6:A, 7ve6:B
83 3dzd:A 368 120 0.2258 0.0761 0.2333 0.001 3dzd:B
84 3q15:D 100 89 0.1935 0.2400 0.2697 0.001
85 1ny5:B 385 117 0.2661 0.0857 0.2821 0.003 4bs1:A, 4bs1:B, 4bt0:A, 4bt0:B, 4bt1:A, 4bt1:B, 4ly6:A, 4ly6:B, 4ly6:C, 4ly6:D, 4ly6:E, 4ly6:G, 4ly6:H, 4ly6:I, 4ly6:J, 4ly6:K, 4ly6:L, 4ly6:M, 4ly6:N, 4ly6:O, 4ly6:P, 4ly6:Q, 4ly6:R, 4ly6:S, 4ly6:T, 4ly6:U, 4ly6:V, 4ly6:W, 4ly6:X, 4lzz:A, 4lzz:B, 4lzz:C, 4lzz:D, 4lzz:E, 4lzz:F, 4lzz:G, 4lzz:H, 4lzz:I, 4lzz:J, 4lzz:K, 4lzz:L, 4lzz:M, 4lzz:N, 4lzz:O, 4lzz:P, 4lzz:Q, 4lzz:R, 4lzz:S, 4lzz:T, 4lzz:U, 4lzz:V, 4lzz:W, 4lzz:X, 3m0e:A, 3m0e:B, 3m0e:C, 3m0e:D, 3m0e:E, 3m0e:F, 3m0e:G, 1ny5:A, 1ny6:A, 1ny6:B, 1ny6:C, 1ny6:D, 1ny6:E, 1ny6:F, 1ny6:G, 1ny6:H, 1ny6:I, 1ny6:J, 1ny6:K, 1ny6:L, 1ny6:M, 1ny6:N, 1zy2:A
86 3i5a:A 319 58 0.1532 0.0596 0.3276 0.005
87 7e1b:A 209 64 0.1532 0.0909 0.2969 0.005 7e1b:B, 7e1b:C, 7e1b:H, 7e1b:D, 7e1b:E, 7e1b:F, 7e1b:G, 7e1h:A, 7e1h:B, 7e1h:E
88 5m7n:B 428 109 0.2661 0.0771 0.3028 0.006
89 4tv5:A 245 63 0.1694 0.0857 0.3333 0.043 4tv6:A
90 7lwb:A 182 91 0.1774 0.1209 0.2418 0.044 7bwt:B, 4lhv:A, 4lhv:B, 4lhv:C, 4lhv:D, 4lhw:A, 4lhw:B, 4lhw:C, 4lhw:D, 4lhw:E, 4lhy:A, 4lhy:B, 4lhz:A, 4lhz:B, 4li0:A, 4li0:B, 3qbt:A, 3qbt:C, 3qbt:E, 3qbt:G, 6rir:A, 6rir:B, 6sq2:A, 6sq2:B, 6stf:A, 6stf:B, 6stf:C, 6stf:D, 6stf:E, 6stg:A, 6stg:B, 5szi:A, 3tnf:A, 6whe:A, 6whe:B, 6yx5:A, 6zsi:A, 6zsi:B, 6zsj:A, 6zsj:B
91 8phn:A 124 115 0.2177 0.2177 0.2348 0.063
92 4nic:A 117 62 0.1452 0.1538 0.2903 0.29 4nic:B, 4nic:C, 4nic:D
93 7pua:IA 704 41 0.1452 0.0256 0.4390 0.47 7pub:IA
94 2ocb:A 173 96 0.2016 0.1445 0.2604 0.50
95 4ldz:A 196 73 0.1694 0.1071 0.2877 0.60 5iuk:C, 5iul:C, 5iul:F, 4ldz:B, 4le0:A, 4le0:B, 7ssj:B, 7ssj:E, 7ssj:F
96 5syt:A 444 50 0.1371 0.0383 0.3400 0.72 4aw6:A, 4aw6:B, 4aw6:D, 4aw6:E, 6bh8:B
97 5szj:A 175 91 0.1694 0.1200 0.2308 1.2 5lpn:A, 5lpn:C
98 5wm3:A 537 51 0.1452 0.0335 0.3529 1.5 5wm2:A, 5wm4:A, 5wm5:A, 5wm6:A, 5wm7:A
99 2bme:A 176 84 0.1694 0.1193 0.2500 3.2 2bmd:A, 2bme:B, 2bme:C, 2bme:D, 1yu9:A, 1z0k:A, 1z0k:C
100 4g2c:B 463 42 0.1210 0.0324 0.3571 3.5 4g2c:A
101 8qcj:A 458 103 0.2016 0.0546 0.2427 3.6 8qcj:B
102 3ut0:A 804 61 0.1774 0.0274 0.3607 3.9 3rrx:A, 3usz:A, 3ut0:B, 3ut0:C, 3ut0:D
103 6ueb:A 2099 24 0.0806 0.0048 0.4167 4.6
104 6o62:A 169 91 0.1774 0.1302 0.2418 5.1
105 6lpw:B 436 60 0.1210 0.0344 0.2500 5.1
106 2imr:A 380 34 0.1129 0.0368 0.4118 5.6
107 2ypt:A 424 46 0.1290 0.0377 0.3478 6.3 2ypt:B, 2ypt:D, 2ypt:E
108 2m98:A 123 55 0.1290 0.1301 0.2909 7.4

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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