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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LIYGNYLHLEKVLNAQELQSETKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVVSRMHRVS
VILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQNMRVPYNRRHYRDNFKGEENELLLKSEQEK
TLLELVEAWLERTPGLEPHGFNFWGKLEKNITRGLEEEFIRIQAKEEQVAEFQKQKEVLLSLFDEKRHEHLLSKGERRLS
YRALQGALMIYFYREEPRFQVPFQLLTSLMDIDSLMTKWRYNHVCMVHRMLGSGYHYLRSTVSDRYKVFVDLFNLSTYLI
PRHWIPKMNPTIHKF

The query sequence (length=335) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6pyz:A 353 349 1.0000 0.9490 0.9599 0.0 6a4i:A, 6a4i:C, 9at2:A, 9at2:B, 9at2:C, 9at2:D, 9b17:A, 9b17:B, 9b17:C, 9b17:D, 9b1q:A, 9b1q:B, 9b1q:C, 9b1q:D, 7lu7:AAA, 7lu7:BBB, 7lu7:DDD, 6pyy:A, 6pyy:B, 6pyy:D, 6pyz:B, 6pyz:D, 8qv7:D, 8r5q:A, 8r5q:B, 8r5q:C, 8r5q:D, 8r5r:A, 8r5r:B, 8r5r:C, 8r5r:D, 5ti9:A, 5ti9:B, 5ti9:D, 5tia:A, 5tia:B, 5tia:D, 6ud5:A, 6ud5:B, 6ud5:C, 6ud5:D, 7ui3:D, 6vbn:A, 6vbn:B, 6vbn:C, 6vbn:D, 8vtq:A, 8vtq:B, 8vtq:C, 8vtq:D, 8vug:A, 8vug:B, 8vug:C, 8vug:D, 8vzv:AAA, 8vzv:BBB, 8vzv:DDD, 8w1h:A, 8w1h:B, 8w1h:C, 8w1h:D, 8w2k:A, 8w2k:B, 8w2k:C, 8w2k:D
2 6pyz:C 333 343 0.9582 0.9640 0.9359 0.0 6a4i:B, 9ezj:B, 7lu7:CCC, 6pyy:C, 8qv7:A, 5ti9:C, 5tia:C, 7ui3:A, 7ui3:C, 8vzv:CCC
3 9ezj:C 315 341 0.9045 0.9619 0.8886 0.0 9ezj:A, 9ezj:D, 8qv7:B, 8qv7:C, 7ui3:B
4 6a4i:D 290 334 0.8627 0.9966 0.8653 0.0
5 4hka:A 345 345 0.6000 0.5826 0.5826 1.09e-135
6 2nox:B 266 324 0.2657 0.3346 0.2747 6.13e-21 2nox:A, 2nox:C, 2nox:D, 2nox:E, 2nox:F, 2nox:G, 2nox:H, 2nox:I, 2nox:J, 2nox:K, 2nox:L, 2nox:M, 2nox:N, 2nox:O, 2nox:P
7 7p46:A 281 127 0.1552 0.1851 0.4094 1.53e-18 3bk9:A, 3bk9:B, 3bk9:C, 3bk9:D, 3bk9:E, 3bk9:F, 3bk9:G, 3bk9:H, 3e08:A, 3e08:B, 3e08:C, 3e08:D, 3e08:E, 3e08:F, 3e08:G, 3e08:H, 2nw7:A, 2nw7:B, 2nw7:C, 2nw7:D, 2nw8:A, 2nw8:B, 2nw9:A, 2nw9:B, 7p46:D, 7p46:B, 7p46:C, 7p46:E, 7p46:G, 7p46:H, 7p46:F, 1yw0:A, 1yw0:B, 1yw0:C
8 7p46:A 281 73 0.0537 0.0641 0.2466 2.8 3bk9:A, 3bk9:B, 3bk9:C, 3bk9:D, 3bk9:E, 3bk9:F, 3bk9:G, 3bk9:H, 3e08:A, 3e08:B, 3e08:C, 3e08:D, 3e08:E, 3e08:F, 3e08:G, 3e08:H, 2nw7:A, 2nw7:B, 2nw7:C, 2nw7:D, 2nw8:A, 2nw8:B, 2nw9:A, 2nw9:B, 7p46:D, 7p46:B, 7p46:C, 7p46:E, 7p46:G, 7p46:H, 7p46:F, 1yw0:A, 1yw0:B, 1yw0:C
9 6dcb:A 225 66 0.0627 0.0933 0.3182 0.036 6dcc:A, 5una:C, 5una:A, 5una:B, 5una:D, 5una:E, 5una:F
10 8cqw:p0 79 67 0.0627 0.2658 0.3134 1.8
11 3qqz:A 243 69 0.0687 0.0947 0.3333 7.9
12 7z1m:O 570 20 0.0358 0.0211 0.6000 8.8 8bws:O, 6cnc:O, 6cnd:O, 6eu0:O, 6eu1:O, 6f44:O, 7z2z:O

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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