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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LHNTIFSETRKFTRESFKEIEHLTARLANDSVARHDFLFNTSIALISDYSGEDSNGNQLQATITIPNEIINPKEYDPSDY
PLAEDESFFKQGHKYDYLVTFRAGSLTNTYEPKTKMYKLHAALDKLMHVRQRKSRFADLWRELCAVIASLDVWYQTTNYP
LRTYVKLLFHRGDEFPFYESPSQDRIIFNDKSVASILPTFVYTCCQVGTAIMSGILTHVESIVAMNHFLHCAKDSYIDEK
LKIKGIGRSWYQEALHNVGQATVPVWSQFNEVIGHRRKSTSEPHFVSSTFISLRAKRAELLYPEFNAYINRAIQLSKTQN
DVANYYAACRAMTNDGTFLATLTELSLDAAVFPRIEQRLVTRPAVLMSNTRHESLKQKYTNGVGSIAQSYLSSFTDEIAK
RVNGIHHDEAWLNFLTTSIVMQAVFAREYRTPERIFKSLKAPIKLVERQQSDRRQRAISGLDNDRLFLSFMPYTIGKQIY
ELNDNAAQGKQAGNAFDIGEMLYWTSQRNVLLSSIDVAGMDASVTTNTKDIYNTFVLDVASKCTVPRFGPYYAKNMEVFE
VGKRQSQVRYVNAAWQACALEAADSQTSTSYESEIFGQVKNAEGTYPSGRADTSTHHTVLLQGLVRGNELKRASDGKNSC
LATIKILGDDIMEIFQGSESDTYDHAMSNANILNESGFATTAELSQNSIVLLQQLVVNGTFWGFADRISLWTREDTKDIG
RLNLAMMELNALIDDLVFRVRRPEGLKMLGFFCGAICLRRFTLSVDNKLYDSTYNNLSKYMTLIKYDKNPDFDSTLMSLI
LPLAWLFMPRGGEYPAYPFERRDGTFTEDESMFTARGAYKRRLLYDVSNIREMIQQNSMALDDDLLHEYGFTGALLLIDL
NILDLIDEVKKEDISPVKVSELATSLEQLGKLGEREKSRRAASDLKIRGHALSNDIVYGYGLQEKIQKSAMAKRVSSRLH
DVIVAKTRDYKISTIPADALRLHEFEVEDVTVDLLPHAKHTSYSSLAYNMSFGSDGWFAFALLGGLDRSANLLRLDVASI
RGNYHKFSYDDPVFKQGYKIYKSDATLLNDFFTAISAGPKEQGILLRAFAYYSLYGNVEYHYVLSPRQLFFLSDNPVSAE
RLVRIPPKYYVSTQCRALYNIFSYLHILRSIANNWGKRLKMVLHPGLIAYVRGTSQGAILPEA

The query sequence (length=1183) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3jb6:A 1196 1192 0.9848 0.9741 0.9773 0.0 5h0r:F, 6ty8:A
2 6k32:A 1208 1206 0.9763 0.9561 0.9577 0.0 3jb7:A, 6ty9:A, 6tz1:A, 6tz2:A
3 3zlb:A 398 184 0.0389 0.1156 0.2500 0.29
4 5gt1:A 153 72 0.0186 0.1438 0.3056 0.52
5 6yu8:A 268 72 0.0194 0.0858 0.3194 1.3
6 8wt1:C 651 73 0.0220 0.0399 0.3562 2.8 8wt1:A, 8wt1:B, 8wt1:D, 8wt1:E, 8wt1:F, 8wt1:G, 8wt1:H
7 1ewq:A 759 104 0.0228 0.0356 0.2596 3.1 1ewq:B, 1fw6:A, 1fw6:B, 1nne:A, 1nne:B
8 7nfe:B 475 106 0.0270 0.0674 0.3019 4.7 8bot:B
9 6d41:B 579 65 0.0186 0.0380 0.3385 8.7 6d41:A, 6d6w:A, 6d6w:B, 6d6w:C, 6d6w:D, 6d7f:A, 6d7f:B, 6d7f:C, 6d7f:D, 6d7f:E, 6d7f:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218