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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LHLISAKASRKYRRTIACLSDTAKKDLERRKQSGAADPAQELSCLKTIKFKLEVPEGSKLPSFDRISQIYNALETIEKGS
LSYLLFALILSGFRIFPNSSAAKTFASSSCYKNDQFASQIKEIFGEMVKNFIPSELESILKKGRRKNNKDWTEENIKRVL
NSEFGRKNSEGSSALFDSFLSKFSQELFRKFDSWNEVNKKYLEAAELLDSMLASYGPFDSVCKMIGDSDSRNSLPDKSTI
AFTNNAEITVDIESSVMPYMAIAALLREYRQSKSKAAPVAYVQSHLTTTNGNGLSWFFKFGLDLIRKAPGSKSLQELFSV
PDDKLDGLKFIKEACEALPEASLLCGEKGELLGYQDFRTSFAGHIDSWVANYVNRLFELIELVNSHSLELFEGLVKNVRQ
TLKKLAGIDPNEQDIKEFYAFSDVLNRLGSIRNQIENLKKLPKLNGLGGGVPKQQELLDKALESVKQIRHYQRIDFERVI
QWAVNEHCLETVPKFLVDAEKKKINKESSTDFAAKENAVRFLLEGIGAAARGKTDSVSKAAYNWFVVNNFLAKKDLNRYF
INCQGCIYKPPYSKRRSLAFALRSDNKDTIEVVWEKFETFYKEISKEIEKFNIFSQEFQTFLHLENLRMKLLLRRIQKPI
PAEIAFFSLPQEYYDSLPPNVAFLTPSEYITQFNLYSSFLNGNLILLRRSRSYLRAKFSWVGNSKLIYAAKEARLWKIPN
AYWKSDEWKMILDSNVLVFDKAGNVLPAPTLKKVCEREGDLRLFYPLLRQLPHDWCYRNPFVKSVGREKNVIEVNKEGEP
KVASALPGSLFRLIGPAPFKSLLDDCFFNPLDKDLRECMLIVDQEISQKVEAQKVEASLESCTYSIAVPIRYHLEEPKVS
NQFENVLAIAQGEAGLAYAVFSLKSIGEAETKPIAVGTIRIPSIRRLIHSVSTYRKKKQRLQNFKQNYDSTAFIMRENVT
GDVCAKIVGLMKEFNAFPVLEYDSRQLSAVYKAVNSHFLYFKEPGRDALRKQLWYGGDSWTIDGIEIVTRERKEDGKEGV
EKIVPLKVFPGRSVSARFTSKTCSCCGRNVFDWLFTEKKAFNVNSKGELTTADGVIQLFEADRSKGPKFYARRKERTPLT
KPIAKGSYSLEEIERRVRTNLRRAPKSKQSRDTSQSQYFCVYKDCALHFSGMQADENAAINIGRRFLTALRKN

The query sequence (length=1193) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7vyx:A 1211 1210 1.0000 0.9851 0.9860 0.0 7vyx:B
2 7v94:A 1076 1139 0.2481 0.2751 0.2599 1.42e-75 7v93:A
3 3cmu:A 1937 86 0.0184 0.0114 0.2558 4.2 3cmt:A, 3cmw:A, 8gms:F, 8gms:G, 8gmt:F, 8gmt:G, 8gmu:F, 8gmu:G, 7jy6:A, 7jy6:B, 7jy6:C, 7jy6:D, 7jy6:E, 7jy6:F, 7jy6:G, 7jy6:H, 7jy6:I, 7jy7:A, 7jy7:B, 7jy7:C, 7jy7:D, 7jy7:E, 7jy7:F, 7jy7:G, 7jy7:H, 7jy7:I, 7jy8:A, 7jy8:B, 7jy8:C, 7jy8:D, 7jy8:E, 7jy8:F, 7jy8:G, 7jy8:H, 7jy8:I, 7jy9:A, 7jy9:C, 7jy9:D, 7jy9:G, 7jy9:E, 7jy9:B, 7jy9:F, 7jy9:H, 7jy9:I, 8trg:A, 8trg:B, 8trg:C, 8trg:D, 8trg:E, 8trg:F, 8trg:G, 8trg:H, 4twz:A, 7ywa:F, 7ywa:G
4 1wdl:A 715 42 0.0151 0.0252 0.4286 5.6 2d3t:A, 2d3t:B, 1wdk:A, 1wdk:B, 1wdl:B, 1wdm:A, 1wdm:B
5 7ny7:A 176 63 0.0184 0.1250 0.3492 5.8
6 4rhm:A 308 53 0.0151 0.0584 0.3396 6.3 4rhl:A, 4rhl:B, 4rhm:B, 4rhm:C
7 6gym:7 408 80 0.0184 0.0539 0.2750 6.3 5oqj:7, 5oqm:7
8 1knp:A 529 57 0.0159 0.0359 0.3333 6.5 1knr:A
9 1uaa:A 636 50 0.0151 0.0283 0.3600 6.9 1uaa:B
10 5ijd:C 137 68 0.0184 0.1606 0.3235 7.3 5ijc:D, 5ijc:C, 5ijd:D, 7mlm:C, 3vq1:C, 3vq1:D, 3vq2:C, 3vq2:D
11 7way:A 960 160 0.0327 0.0406 0.2437 7.5 7waz:A, 7wb1:A
12 7ml3:7 548 80 0.0184 0.0401 0.2750 7.9
13 7k04:7 638 80 0.0184 0.0345 0.2750 8.3 5fmf:1, 7m2u:7, 7ml0:7, 7ml1:7, 7ml2:7, 5sva:Z
14 7zsa:7 616 80 0.0184 0.0357 0.2750 8.3 8cen:7, 8ceo:7, 7o4i:7, 7o4j:7, 7o4k:7, 7o4l:7, 7o72:7, 7o73:7, 7o75:7, 7zs9:7, 7zsb:7
15 7wkw:B 377 50 0.0151 0.0477 0.3600 10.0 7wkw:A, 7xxb:A, 7xxb:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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