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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LEIPTAIKPRDGRFGSGPSKVRLEQLQTLTTTAAALFGTSHRQAPVKNLVGRVRSGLAELFSLPDGYEVILGNGGATAFW
DAAAFGLIDKRSLHLTYGEFSAKFASAVSKNPFVGEPIIITSDPGSAPEPQTDPSVDVIAWAHNETSTGVAVAVRRPEGS
DDALVVIDATSGAGGLPVDIAETDAYYFAPQKNFASDGGLWLAIMSPAALSRIEAIAATGRWVPDFLSLPIAVENSLKNQ
TYNTPAIATLALLAEQIDWLVGNGGLDWAVKRTADSSQRLYSWAQERPYTTPFVTDPGLRSQVVGTIDFVDDVDAGTVAK
ILRANGIVDTEPYRKLGRNQLRVAMFPAVEPDDVSALTECVDWVVERL

The query sequence (length=368) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2fyf:A 368 368 0.9973 0.9973 0.9973 0.0 2fyf:B, 3vom:A, 3vom:B
2 3ffr:A 361 357 0.2473 0.2521 0.2549 4.60e-23
3 5yb0:B 349 362 0.2120 0.2235 0.2155 2.93e-18 5yb0:A, 5yb0:C, 5yb0:D, 5yb0:E, 5yb0:F, 5yb0:G, 5yb0:H, 5yb0:I, 5yb0:J, 5yb0:K, 5yd2:A, 5yd2:B
4 8a5v:E 366 378 0.2527 0.2541 0.2460 1.63e-16 8a5v:C, 8a5v:F, 8a5v:B, 8a5v:A, 8a5v:G, 8a5v:H, 8a5w:D, 8a5w:C, 8a5w:E, 8a5w:F, 8a5w:B, 8a5w:A, 8a5w:H, 3e77:A, 3e77:B
5 3qbo:B 359 284 0.1957 0.2006 0.2535 8.48e-10 3qbo:A
6 2dr1:A 381 384 0.2174 0.2100 0.2083 8.65e-10 2dr1:B
7 4azj:A 360 366 0.2147 0.2194 0.2158 2.44e-09 4azj:B, 4azk:A, 4azk:B, 2bhx:A, 2bhx:B, 2bi1:A, 2bi1:B, 2bi2:A, 2bi2:B, 2bi3:A, 2bi3:B, 2bi5:A, 2bi5:B, 2bi9:A, 2bi9:B, 2bia:A, 2bia:B, 2bie:A, 2bie:B, 2big:A, 2big:B, 1w23:A, 1w23:B
8 1bt4:A 361 369 0.2147 0.2188 0.2141 2.73e-09 2c0r:A, 2c0r:B, 1w3u:A
9 6czy:A 362 262 0.1739 0.1768 0.2443 1.75e-08 6czy:B, 6czy:C, 6czy:D, 6czz:A, 6czz:B, 6czz:C, 6czz:D
10 1bjo:A 360 369 0.2255 0.2306 0.2249 5.03e-07 1bjo:B
11 7t7j:B 360 284 0.1793 0.1833 0.2324 6.70e-07 7t7j:A
12 2yri:A 352 291 0.1957 0.2045 0.2474 0.003 2yri:B, 2yrr:A, 2yrr:B
13 1m32:B 362 281 0.1739 0.1768 0.2278 0.005 1m32:A, 1m32:C, 1m32:D, 1m32:E, 1m32:F
14 1iug:A 348 207 0.1386 0.1466 0.2464 0.005 1iug:B
15 6xdk:D 359 288 0.1766 0.1811 0.2257 0.015 6xdk:B, 6xdk:A, 6xdk:C
16 3zrq:A 382 231 0.1603 0.1545 0.2554 0.019 3zrp:A, 3zrp:B, 3zrq:B, 3zrr:A, 3zrr:B
17 3qm2:B 331 163 0.1168 0.1299 0.2638 0.053 3qm2:A
18 7cep:A 414 171 0.1250 0.1111 0.2690 0.51 7ceo:A, 7cer:A, 7ces:A, 7e6b:A, 7e6c:A, 7e6e:A, 7e6f:A, 5j8q:A, 6kfz:A, 7xej:A, 7xek:A, 7xen:A, 7xep:A, 7xet:A, 5xt5:A, 5xt5:B, 5xt6:A, 5xt6:B, 5zsk:A, 5zso:A
19 1n31:A 386 53 0.0462 0.0440 0.3208 0.52 1elq:A, 1elq:B, 1elu:A, 1elu:B, 1n2t:A, 1n2t:B, 1n31:B
20 3isl:A 387 72 0.0625 0.0594 0.3194 0.55 3isl:B
21 7d4i:3B 242 74 0.0571 0.0868 0.2838 1.9 7aju:CB, 7d4i:3C, 7d5s:3C, 7d5t:3B, 7d5t:3C, 7d63:3C, 6ke6:3C, 6lqp:3C, 6lqq:3C, 6lqr:3C, 6lqs:3C, 6lqt:3C, 6lqu:3C, 6lqv:3C, 7suk:SD, 5wlc:SD, 6zqd:CA, 6zqd:CB
22 6pk3:B 400 85 0.0679 0.0625 0.2941 2.1 6pk1:A, 6pk1:B, 6pk3:A
23 2wym:A 303 68 0.0543 0.0660 0.2941 2.6 2wym:B, 2wym:C, 2wym:D, 2wym:E, 2wym:F
24 6pd2:C 616 79 0.0543 0.0325 0.2532 2.8 6pd1:A, 6pd1:B, 6pd1:D, 6pd2:A, 6pd2:B, 6pd2:D
25 1fcv:A 324 65 0.0516 0.0586 0.2923 3.3
26 3afg:B 507 83 0.0598 0.0434 0.2651 4.2 3afg:A
27 8wm6:e 169 72 0.0435 0.0947 0.2222 4.3 8wmv:e, 8wmw:e
28 7x6v:A 1381 109 0.0842 0.0224 0.2844 6.2
29 7x6s:A 1453 109 0.0842 0.0213 0.2844 6.2 5ltf:A, 5ltn:A, 5ltn:B, 5t2t:A
30 4ifd:H 295 57 0.0489 0.0610 0.3158 8.0 5c0x:H, 6fsz:HH, 5jea:H, 5k36:H, 8qcf:I
31 7vwt:A 326 39 0.0408 0.0460 0.3846 8.7 7vwt:B
32 8odq:D 410 72 0.0652 0.0585 0.3333 9.9 8odq:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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