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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LAAIQNARDLEELKALKARYLGKKGLLTQEMKGLSALPLEERRKRGQELNAIKAALEAALEAREKALEEAALKEALERER
VDVSLPGASLFSGGLHPITLMERELVEIFRALGYQAVEGPEVESEFFNFDALNIPEHHPARDMWDTFWLTGEGFRLEGPL
GEEVEGRLLLRTHTSPMQVRYMVAHTPPFRIVVPGRVFRFEQTDATHEAVFHQLEGLVVGEGIAMAHLKGAIYELAQALF
GPDSKVRFQPVYFPFVEPGAQFAVWWPEGGKWLELGGAGMVHPKVFQAVDAYRERLGLPPAYRGVTGFAFGLGVERLAML
RYGIPDIRYFFGGRLKFLEQFKGVL

The query sequence (length=345) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1eiy:A 345 345 1.0000 1.0000 1.0000 0.0 2akw:A, 2aly:A, 2amc:A, 1b70:A, 1b7y:A, 3hfz:A, 2iy5:A, 1jjc:A, 3teh:A, 4tva:A
2 3pco:C 323 341 0.4522 0.4830 0.4575 1.27e-97 6oz5:A, 6oz5:C, 6p24:A, 6p26:A, 6p26:C, 3pco:A
3 6p8t:H 326 336 0.4116 0.4356 0.4226 1.93e-87 6p8t:C, 6p8t:D, 6p8t:G
4 7k98:A 343 338 0.3942 0.3965 0.4024 1.10e-82 7daw:A, 7db7:A, 7db8:A, 7k98:D, 7k9m:A, 7ka0:A, 7ka0:D, 7kab:A
5 4p72:D 244 269 0.3710 0.5246 0.4758 7.34e-82 4p72:C, 4p73:C, 4p73:D, 4p74:C, 4p74:D, 4p75:C, 4p75:D
6 2rhs:C 271 285 0.3536 0.4502 0.4281 1.84e-75 2rhq:A, 2rhs:A
7 7by6:A 299 284 0.2551 0.2943 0.3099 6.84e-38
8 7dpi:C 292 295 0.2493 0.2945 0.2915 1.13e-36 7dpi:A
9 3l4g:C 508 276 0.2696 0.1831 0.3370 1.82e-36 3l4g:A, 3l4g:E, 3l4g:G, 3l4g:I, 3l4g:K, 3l4g:M, 3l4g:O
10 5mgu:A 407 255 0.2290 0.1941 0.3098 2.16e-24 3cmq:A, 3hfv:A, 5mgh:A, 5mgw:A, 8p8x:A, 3teg:A, 3tup:A
11 5x6c:A 539 148 0.1304 0.0835 0.3041 2.83e-08 5x6c:B
12 2du4:A 466 293 0.1971 0.1459 0.2321 5.78e-04 2du3:B, 2du5:B, 2du6:B
13 2du3:A 534 182 0.1217 0.0787 0.2308 0.003 2du5:A, 2du6:A
14 4v58:G 2060 102 0.0986 0.0165 0.3333 1.1 4v58:H, 4v58:I, 4v58:J, 4v58:K, 4v58:L, 4v59:G, 4v59:H, 4v59:I, 4v59:J, 4v59:K, 4v59:L
15 2mum:A 50 29 0.0290 0.2000 0.3448 2.6
16 3v70:A 217 61 0.0696 0.1106 0.3934 3.0 3v70:B
17 1u1h:A 746 46 0.0464 0.0214 0.3478 3.5 1u1j:A, 1u1u:A, 1u22:A
18 8a1y:F 408 56 0.0580 0.0490 0.3571 4.3 8a1t:F, 8a1u:F, 8a1v:F, 8a1w:F, 8a1x:F, 8acw:F, 8acy:F, 8ad0:F, 8ad3:A, 8ad3:B, 8ad4:A, 8ad4:B, 8ad5:A, 8ad5:B, 4u9u:A, 4u9u:B, 4uaj:A, 7xk3:F, 7xk4:F, 7xk5:F, 7xk6:F, 7xk7:F
19 2aly:B 785 143 0.1188 0.0522 0.2867 5.0 2amc:B, 1eiy:B, 3hfz:B, 2iy5:B, 1jjc:B, 3teh:B, 4tva:B
20 3upl:A 437 41 0.0435 0.0343 0.3659 6.2 3upl:B, 3upy:A, 3upy:B
21 5tue:A 388 51 0.0522 0.0464 0.3529 6.9 5tue:B, 5tuf:A, 5tuf:B, 5tui:A, 5tui:B
22 8wnf:A 918 26 0.0377 0.0142 0.5000 7.1 8wng:A, 8wni:A, 8wnj:A, 8wo2:A, 8wo3:A
23 4pof:A 255 32 0.0377 0.0510 0.4062 9.2 5iy0:A, 5iy0:B, 5iy0:C, 5iy0:D, 5iy0:E, 5iy0:F, 4pof:B, 4pof:C, 4pof:D, 4pof:E, 4pof:F, 4pog:A, 4pog:E, 4pog:F, 4pog:K, 4pog:L, 4pog:G, 4pog:H, 4pog:I, 4pog:J, 4pog:B, 4pog:C, 4pog:D, 4ywl:A, 4ywl:B, 4ywl:C, 4ywl:D, 4ywl:E, 4ywl:F, 4ywl:G, 4ywl:H, 4ywl:I, 4ywl:J, 4ywm:A, 4ywm:B, 4ywm:C, 4ywm:D, 4ywm:E, 4ywm:F, 4ywm:G, 4ywm:H, 4ywm:I, 4ywm:J

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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