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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KYRVRKNVLHLTDTEKRDFVRTVLILKEKGIYDRYIAWHGAAGKFHTPPGSDRNAAHMSSAFLPWHREYLLRFERDLQSI
NPEVTLPYWEWETDAQMQDPSQSQIWSADFMGGNGNPIKDFIVDTGPFAAGRWTTIDEQGNPSGGLKRNFGATKEAPTLP
TRDDVLNALKITQYDTPPWDMTSQNSFRNQLEGFINGPQLHNRVHRWVGGQMGVVPTAPNDPVFFLHHANVDRIWAVWQI
IYQPMKNGPFGQNFRDPMYPWNTTPEDVMNHRKLGYVY

The query sequence (length=278) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8hpi:A 289 283 0.9676 0.9308 0.9505 0.0 4d87:A, 4d87:B, 6ei4:A, 6ei4:B, 4hd4:A, 4hd4:B, 4hd6:A, 4hd6:B, 4hd7:A, 4hd7:B, 8hpi:B, 5i38:A, 5i38:B, 5i3a:A, 5i3a:B, 5i3b:A, 5i3b:B, 4j6t:A, 4j6t:B, 4j6v:A, 4j6v:B, 3nm8:A, 3nm8:B, 3npy:A, 3npy:B, 3nq0:A, 3nq0:B, 3nq1:A, 3nq1:B, 3nq5:A, 3nq5:B, 3ntm:A, 3ntm:B, 5oae:A, 5oae:B, 4p6r:A, 4p6r:B, 4p6s:A, 4p6s:B, 4p6t:A, 4p6t:B, 6qxd:A, 6qxd:B
2 5z0f:A 279 276 0.4317 0.4301 0.4348 3.09e-62 2ahk:A, 2ahl:A, 3aws:A, 3awt:A, 3awu:A, 3awv:A, 3aww:A, 3awx:A, 3awy:A, 3awz:A, 3ax0:A, 7cit:A, 7ciy:A, 1wx2:A, 1wx4:A, 5z0d:A, 5z0e:A, 5z0g:A, 5z0h:A, 5z0i:A, 5z0j:A, 5z0k:A, 5z0l:A, 5z0m:A, 2zmx:A, 2zmy:A, 2zmz:A, 2zwd:A, 2zwe:A, 2zwf:A, 2zwg:A
3 6j2u:B 273 276 0.4101 0.4176 0.4130 7.01e-61
4 9ey8:DA 450 341 0.3417 0.2111 0.2786 4.51e-27 9ey5:A, 9ey6:A, 9ey7:A, 9ey8:AA, 9ey8:BA, 9ey8:CA, 5m8l:A, 5m8l:C, 5m8l:B, 5m8l:D, 5m8m:A, 5m8m:B, 5m8m:C, 5m8m:D, 5m8n:A, 5m8n:C, 5m8n:D, 5m8n:B, 5m8o:B, 5m8o:C, 5m8o:A, 5m8o:D, 5m8p:A, 5m8p:B, 5m8p:C, 5m8p:D, 5m8q:A, 5m8q:C, 5m8q:D, 5m8q:B, 5m8r:A, 5m8r:B, 5m8r:C, 5m8r:D, 5m8s:A, 5m8s:B, 5m8s:D, 5m8s:C, 5m8t:A, 5m8t:B, 5m8t:C, 5m8t:D
5 4bed:A 1664 302 0.3058 0.0511 0.2815 9.50e-19 4bed:C
6 4bed:A 1664 252 0.2338 0.0391 0.2579 1.06e-15 4bed:C
7 4bed:A 1664 258 0.2482 0.0415 0.2674 1.04e-12 4bed:C
8 4bed:A 1664 278 0.2518 0.0421 0.2518 1.94e-12 4bed:C
9 4yd9:A 1656 303 0.2662 0.0447 0.2442 8.27e-17 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
10 4yd9:A 1656 305 0.2950 0.0495 0.2689 3.93e-16 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
11 4yd9:A 1656 300 0.2806 0.0471 0.2600 1.17e-14 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
12 4yd9:A 1656 312 0.2806 0.0471 0.2500 1.84e-12 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
13 4yd9:B 825 300 0.2770 0.0933 0.2567 1.03e-16 4yd9:E, 4yd9:H, 4yd9:K, 4yd9:N, 4yd9:Q, 4yd9:T, 4yd9:W, 4yd9:Z, 4yd9:c
14 4yd9:B 825 302 0.2590 0.0873 0.2384 1.44e-13 4yd9:E, 4yd9:H, 4yd9:K, 4yd9:N, 4yd9:Q, 4yd9:T, 4yd9:W, 4yd9:Z, 4yd9:c
15 4bed:B 1734 308 0.2914 0.0467 0.2630 1.71e-16 4bed:D, 3qjo:A, 3qjo:B
16 4bed:B 1734 274 0.2266 0.0363 0.2299 5.03e-13 4bed:D, 3qjo:A, 3qjo:B
17 4bed:B 1734 305 0.2806 0.0450 0.2557 7.35e-13 4bed:D, 3qjo:A, 3qjo:B
18 4bed:B 1734 273 0.2302 0.0369 0.2344 2.31e-10 4bed:D, 3qjo:A, 3qjo:B
19 1lnl:A 408 300 0.2770 0.1887 0.2567 2.96e-13 1lnl:B, 1lnl:C
20 4z11:A 513 205 0.2230 0.1209 0.3024 6.20e-13 4z0y:A, 4z0y:B, 4z0y:D, 4z0y:C, 4z0z:A, 4z0z:B, 4z0z:C, 4z0z:D, 4z10:A, 4z10:C, 4z10:B, 4z10:D, 4z10:E, 4z10:F, 4z11:B, 4z11:C, 4z11:D, 4z12:A, 4z12:B, 4z13:A, 4z13:B, 4z14:D, 4z14:B, 4z14:H, 4z14:F, 4z14:C, 4z14:E, 4z14:G, 4z14:A
21 4j3r:A 372 328 0.2986 0.2231 0.2530 1.36e-12 6gsg:A, 4j3p:A, 4j3q:A, 4j3q:B, 5or3:A, 5or3:B, 5or3:C, 5or3:D, 5or4:A, 5or4:B, 5or4:C, 5or4:D
22 6z1s:A 381 287 0.2734 0.1995 0.2648 6.06e-12
23 8tnv:A 393 301 0.2770 0.1959 0.2558 6.87e-12 8tnv:B
24 4yd9:L 366 273 0.2302 0.1749 0.2344 2.32e-11 4yd9:C, 4yd9:a, 4yd9:F, 4yd9:R, 4yd9:I, 4yd9:O, 4yd9:U, 4yd9:X, 4yd9:d
25 5zre:B 474 357 0.3237 0.1899 0.2521 2.13e-10 5zre:A, 5zre:C
26 5ce9:A 339 242 0.2266 0.1858 0.2603 6.20e-10 5ce9:B
27 8bbq:A 324 216 0.2194 0.1883 0.2824 9.67e-10 8bbq:B, 8bbr:A, 8bbr:B
28 1js8:A 382 100 0.1259 0.0916 0.3500 2.58e-09 1js8:B
29 1js8:A 382 94 0.1007 0.0733 0.2979 0.003 1js8:B
30 6els:A 459 244 0.2158 0.1307 0.2459 2.87e-09 6elt:A, 6elv:A
31 3w6w:A 583 80 0.0971 0.0463 0.3375 1.01e-08 6ju7:A, 6ju7:B, 6ju8:A, 6ju8:B, 6ju9:A, 6ju9:B
32 1bug:A 336 195 0.1871 0.1548 0.2667 1.28e-08 1bug:B
33 6jua:A 533 67 0.0899 0.0469 0.3731 4.80e-08 6jub:A, 6jud:A
34 6ju4:B 560 67 0.0899 0.0446 0.3731 4.85e-08 6ju4:A, 6ju5:A, 6ju5:B, 6jua:B, 6jub:B, 6juc:A, 6juc:B, 6jud:B, 3w6w:B
35 5zrd:A 534 318 0.3022 0.1573 0.2642 9.74e-08 5zrd:B, 5zrd:C, 5zrd:D
36 6hqi:A 444 249 0.2230 0.1396 0.2490 1.14e-07
37 2y9w:A 391 52 0.0827 0.0588 0.4423 1.27e-06 2y9w:B, 2y9x:A, 2y9x:B, 2y9x:C, 2y9x:D
38 5m6b:C 514 246 0.2338 0.1265 0.2642 1.41e-06
39 4oua:B 557 115 0.1295 0.0646 0.3130 1.23e-04 5m6b:B, 5m6b:A, 5m6b:D, 4oua:A
40 3wky:A 655 42 0.0540 0.0229 0.3571 0.26 3wky:B
41 6vu9:A 631 94 0.0863 0.0380 0.2553 0.90
42 8wwd:A 337 37 0.0504 0.0415 0.3784 2.8 8wwd:B, 8wwd:C, 8wwd:D
43 5w4y:A 450 48 0.0576 0.0356 0.3333 3.2 5w4y:B, 5w4z:A, 5w4z:B
44 8yl9:A 346 31 0.0468 0.0376 0.4194 5.5 8yl9:B, 8yl9:I
45 8jib:E 661 31 0.0504 0.0212 0.4516 8.5 8ji8:A, 8ji8:B, 8ji8:C, 8ji8:D, 8jib:A, 8jib:B, 8jib:C, 8jib:D, 8jib:F, 8jib:G, 8jib:H, 8jib:I, 8jib:J, 8jib:K, 8jib:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218