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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KYRVRKNVLHLTDTEKRDFVRTVLILKEKGIYDRYIAWHGAAGKFHTPPGSDRNAAHMSSAFLPWHREYLLRFERDLQSI
NPEVTLPYWEWETDAQMQDPSQSQIWSADFMGGNGNPIKDFIVDTGPFAAGRWTTIDEQGNPSGGLKRNFGATKEAPTLP
TRDDVLNALKITQYDTPPWDMTSQNSFRNQLEGFINGPQLHNRVHHWVGGQMGVVPTAPNDPVFFLHHANVDRIWAVWQI
IHRNQNYQPMKNGPFGQNFRDPMYPWNTTPEDVMNHRKLGYVYDI

The query sequence (length=285) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8hpi:A 289 285 0.9614 0.9481 0.9614 0.0 4d87:A, 4d87:B, 6ei4:A, 6ei4:B, 4hd4:A, 4hd4:B, 4hd6:A, 4hd6:B, 4hd7:A, 4hd7:B, 8hpi:B, 5i38:A, 5i38:B, 5i3a:A, 5i3a:B, 5i3b:A, 5i3b:B, 4j6t:A, 4j6t:B, 4j6v:A, 4j6v:B, 3nm8:A, 3nm8:B, 3npy:A, 3npy:B, 3nq0:A, 3nq0:B, 3nq1:A, 3nq1:B, 3nq5:A, 3nq5:B, 3ntm:A, 3ntm:B, 5oae:A, 5oae:B, 4p6r:A, 4p6r:B, 4p6s:A, 4p6s:B, 4p6t:A, 4p6t:B, 6qxd:A, 6qxd:B
2 5z0f:A 279 284 0.4316 0.4409 0.4331 7.50e-65 2ahk:A, 2ahl:A, 3aws:A, 3awt:A, 3awu:A, 3awv:A, 3aww:A, 3awx:A, 3awy:A, 3awz:A, 3ax0:A, 7cit:A, 7ciy:A, 1wx2:A, 1wx4:A, 5z0d:A, 5z0e:A, 5z0g:A, 5z0h:A, 5z0i:A, 5z0j:A, 5z0k:A, 5z0l:A, 5z0m:A, 2zmx:A, 2zmy:A, 2zmz:A, 2zwd:A, 2zwe:A, 2zwf:A, 2zwg:A
3 6j2u:B 273 276 0.4035 0.4212 0.4167 7.56e-64
4 9ey8:DA 450 344 0.3404 0.2156 0.2820 3.61e-27 9ey5:A, 9ey6:A, 9ey7:A, 9ey8:AA, 9ey8:BA, 9ey8:CA, 5m8l:A, 5m8l:C, 5m8l:B, 5m8l:D, 5m8m:A, 5m8m:B, 5m8m:C, 5m8m:D, 5m8n:A, 5m8n:C, 5m8n:D, 5m8n:B, 5m8o:B, 5m8o:C, 5m8o:A, 5m8o:D, 5m8p:A, 5m8p:B, 5m8p:C, 5m8p:D, 5m8q:A, 5m8q:C, 5m8q:D, 5m8q:B, 5m8r:A, 5m8r:B, 5m8r:C, 5m8r:D, 5m8s:A, 5m8s:B, 5m8s:D, 5m8s:C, 5m8t:A, 5m8t:B, 5m8t:C, 5m8t:D
5 4bed:A 1664 301 0.3053 0.0523 0.2890 8.27e-21 4bed:C
6 4bed:A 1664 299 0.2596 0.0445 0.2475 1.48e-16 4bed:C
7 4bed:A 1664 248 0.2211 0.0379 0.2540 2.73e-12 4bed:C
8 4bed:A 1664 277 0.2386 0.0409 0.2455 8.76e-12 4bed:C
9 4yd9:A 1656 304 0.2667 0.0459 0.2500 3.14e-18 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
10 4yd9:A 1656 311 0.2947 0.0507 0.2701 3.30e-17 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
11 4yd9:A 1656 302 0.2772 0.0477 0.2616 1.24e-16 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
12 4yd9:A 1656 313 0.2772 0.0477 0.2524 1.14e-13 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
13 4bed:B 1734 309 0.2947 0.0484 0.2718 5.13e-18 4bed:D, 3qjo:A, 3qjo:B
14 4bed:B 1734 304 0.2316 0.0381 0.2171 3.99e-14 4bed:D, 3qjo:A, 3qjo:B
15 4bed:B 1734 307 0.2912 0.0479 0.2704 6.39e-14 4bed:D, 3qjo:A, 3qjo:B
16 4bed:B 1734 273 0.2211 0.0363 0.2308 1.85e-11 4bed:D, 3qjo:A, 3qjo:B
17 4yd9:B 825 308 0.2807 0.0970 0.2597 3.89e-17 4yd9:E, 4yd9:H, 4yd9:K, 4yd9:N, 4yd9:Q, 4yd9:T, 4yd9:W, 4yd9:Z, 4yd9:c
18 4yd9:B 825 302 0.2526 0.0873 0.2384 1.42e-15 4yd9:E, 4yd9:H, 4yd9:K, 4yd9:N, 4yd9:Q, 4yd9:T, 4yd9:W, 4yd9:Z, 4yd9:c
19 1lnl:A 408 308 0.2772 0.1936 0.2565 6.42e-15 1lnl:B, 1lnl:C
20 8tnv:A 393 301 0.2702 0.1959 0.2558 1.97e-14 8tnv:B
21 4j3r:A 372 331 0.2982 0.2285 0.2568 1.36e-13 6gsg:A, 4j3p:A, 4j3q:A, 4j3q:B, 5or3:A, 5or3:B, 5or3:C, 5or3:D, 5or4:A, 5or4:B, 5or4:C, 5or4:D
22 6z1s:A 381 287 0.2667 0.1995 0.2648 2.98e-12
23 4z11:A 513 200 0.2105 0.1170 0.3000 8.29e-12 4z0y:A, 4z0y:B, 4z0y:D, 4z0y:C, 4z0z:A, 4z0z:B, 4z0z:C, 4z0z:D, 4z10:A, 4z10:C, 4z10:B, 4z10:D, 4z10:E, 4z10:F, 4z11:B, 4z11:C, 4z11:D, 4z12:A, 4z12:B, 4z13:A, 4z13:B, 4z14:D, 4z14:B, 4z14:H, 4z14:F, 4z14:C, 4z14:E, 4z14:G, 4z14:A
24 4yd9:L 366 272 0.2175 0.1694 0.2279 3.12e-11 4yd9:C, 4yd9:a, 4yd9:F, 4yd9:R, 4yd9:I, 4yd9:O, 4yd9:U, 4yd9:X, 4yd9:d
25 5zre:B 474 357 0.3158 0.1899 0.2521 5.74e-10 5zre:A, 5zre:C
26 8bbq:A 324 237 0.2316 0.2037 0.2785 5.97e-10 8bbq:B, 8bbr:A, 8bbr:B
27 1js8:A 382 100 0.1193 0.0890 0.3400 1.03e-09 1js8:B
28 1js8:A 382 94 0.0982 0.0733 0.2979 0.003 1js8:B
29 5ce9:A 339 198 0.1789 0.1504 0.2576 4.04e-09 5ce9:B
30 6els:A 459 200 0.1825 0.1133 0.2600 6.27e-09 6elt:A, 6elv:A
31 3w6w:A 583 81 0.0947 0.0463 0.3333 8.52e-09 6ju7:A, 6ju7:B, 6ju8:A, 6ju8:B, 6ju9:A, 6ju9:B
32 1bug:A 336 245 0.2140 0.1815 0.2490 8.65e-09 1bug:B
33 6jua:A 533 68 0.0877 0.0469 0.3676 4.12e-08 6jub:A, 6jud:A
34 6ju4:B 560 68 0.0877 0.0446 0.3676 4.21e-08 6ju4:A, 6ju5:A, 6ju5:B, 6jua:B, 6jub:B, 6juc:A, 6juc:B, 6jud:B, 3w6w:B
35 6hqi:A 444 249 0.2211 0.1419 0.2530 5.25e-08
36 5zrd:A 534 319 0.2982 0.1592 0.2665 1.34e-07 5zrd:B, 5zrd:C, 5zrd:D
37 2y9w:A 391 52 0.0807 0.0588 0.4423 1.30e-06 2y9w:B, 2y9x:A, 2y9x:B, 2y9x:C, 2y9x:D
38 5m6b:C 514 246 0.2246 0.1245 0.2602 8.41e-06
39 4oua:B 557 115 0.1228 0.0628 0.3043 8.16e-04 5m6b:B, 5m6b:A, 5m6b:D, 4oua:A
40 3wky:A 655 47 0.0632 0.0275 0.3830 0.58 3wky:B
41 5w4y:A 450 48 0.0561 0.0356 0.3333 3.3 5w4y:B, 5w4z:A, 5w4z:B
42 5lhd:C 905 131 0.1053 0.0331 0.2290 4.3 6atk:C, 6atk:A, 6atk:B, 4fyq:A, 4fyr:A, 4fys:A, 4fyt:A, 5lhd:D, 5lhd:A, 5lhd:B, 6u7e:A, 6u7e:B, 6u7f:A, 6u7f:B, 6u7g:A, 6u7g:B, 7vpq:A, 7vpq:C, 7vpq:E
43 8yl9:A 346 31 0.0456 0.0376 0.4194 5.4 8yl9:B, 8yl9:I
44 8b80:A 474 88 0.0842 0.0506 0.2727 7.5 8b81:A, 8b81:B, 5okb:B, 5okb:C, 5okb:D, 5oke:C, 5oke:D, 5oke:A, 5oke:B, 5okg:C, 5okg:D, 5okg:A, 5okg:B, 5okk:A, 5okk:B, 5okq:A, 5okq:B, 5okr:A, 5okr:B, 5oks:A, 5oks:B, 4zen:A, 4zen:B, 4zep:A, 4zep:B, 4zfm:D, 4zfm:A, 4zfm:B, 4zfm:C
45 8jib:E 661 31 0.0491 0.0212 0.4516 9.0 8ji8:A, 8ji8:B, 8ji8:C, 8ji8:D, 8jib:A, 8jib:B, 8jib:C, 8jib:D, 8jib:F, 8jib:G, 8jib:H, 8jib:I, 8jib:J, 8jib:K, 8jib:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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