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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KVYTIDEAARTAKFDETVEVHAKLGIDPRRSDQNVRGTVSLPHGLGKQVRVLAIAKGEKIKEAEEAGADYVGGEEIIQKI
LDGWMDFVMGAVGSKLGRILGPRGLNPKAGTVGFNIGEIIREIKAGRIEFRNDKTGAIHAPVGKASFPPEKLADNIRAFI
RALEAHKPEGAKGTFLRSVYVTTTMGPSVR

The query sequence (length=190) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4qvi:A 229 206 0.9842 0.8166 0.9078 9.54e-128 7a5f:n, 7a5g:n, 7a5j:n, 5a9z:AC, 5aa0:AC, 2hw8:A, 5imq:Z, 5imr:Z, 7lh5:BC, 7lh5:DC, 6n1d:AL01, 6n1d:BL01, 5npm:A, 2om7:K, 5ot7:f, 6q95:A, 4qg3:A, 4reo:A, 4u1u:B5, 4u1v:B5, 4u20:B5, 4u24:B5, 4u25:B5, 4u26:B5, 4u27:B5, 3u4m:A, 3u56:A, 3umy:A, 5uq7:C, 5uq8:C, 4v4p:AC, 4v4x:BC, 4v4y:BC, 4v4z:BC, 4v51:BC, 4v51:DC, 4v5a:BC, 4v5a:DC, 4v5c:BC, 4v5c:DC, 4v5d:BC, 4v5d:DC, 4v5e:BC, 4v5e:DC, 4v5f:BC, 4v5f:DC, 4v5g:BC, 4v5g:DC, 4v5k:BC, 4v5k:DC, 4v5l:BC, 4v5m:BC, 4v5n:BC, 4v5p:BC, 4v5p:DC, 4v5q:BC, 4v5q:DC, 4v5r:BC, 4v5r:DC, 4v5s:BC, 4v5s:DC, 4v68:BC, 4v6a:BC, 4v6a:DC, 4v7l:BC, 4v7l:DC, 4v7m:BC, 4v7m:DC, 4v8j:BC, 4v8j:DC, 4v8o:BC, 4v8q:AC, 4v8u:BC, 4v8u:DC, 4v8y:By, 4v8y:CL, 4v90:BC, 4v97:BC, 4v97:DC, 4v9h:BC, 4v9j:BC, 4v9j:DC, 4v9k:BC, 4v9k:DC, 4v9l:BC, 4v9l:DC, 4v9m:BC, 4v9m:DC, 4w29:BC, 4w29:DC, 4wf1:B5, 4woi:B5, 1zho:A, 1zho:C, 1zho:E, 1zho:G, 5zlu:Y
2 5dm6:0 224 205 0.6526 0.5536 0.6049 4.08e-82 5dm7:0
3 4v61:BD 227 190 0.5053 0.4229 0.5053 3.59e-61
4 4v9i:BC 190 78 0.4105 0.4105 1.0000 6.60e-59 4v9i:DC, 4wt8:CA, 4wt8:DA
5 6ha8:8 212 206 0.5632 0.5047 0.5194 1.06e-55
6 7p7q:F 226 206 0.5158 0.4336 0.4757 1.45e-51 7p7r:F, 7p7s:F, 7p7t:F
7 5ady:5 234 205 0.4895 0.3974 0.4537 6.59e-48 4csu:5, 6dnc:E, 6enj:7, 6enu:7, 3j46:5, 3j5s:F, 3j8g:5, 3j9z:LC, 3ja1:LC, 3jcd:5, 3jce:5, 8rcs:a2, 8rct:a2, 5u9f:03, 5u9g:03, 5uyk:03, 4v4v:B2, 4v4w:B2, 4v5h:B5, 4v69:B5, 4v6k:AC, 4v6l:BC, 4v6m:B5, 4v6n:AC, 4v6o:BC, 4v6p:BC, 4v6q:BC, 4v6r:BC, 4v6s:AC, 4v6v:BC, 4v6y:B5, 4v6z:B5, 4v70:B5, 4v71:B5, 4v72:B5, 4v73:B5, 4v74:B5, 4v75:B5, 4v76:B5, 4v77:B5, 4v78:B5, 4v79:B5, 4v7a:B5, 4v7c:BC, 4v7d:AC, 4v7i:A5
8 7msc:8 230 204 0.4842 0.4000 0.4510 1.51e-44 7msh:8, 7msm:8, 7msz:8, 7mt2:8, 7mt3:8, 7mt7:8
9 8fmw:AC 221 206 0.4211 0.3620 0.3883 7.60e-43
10 2vpl:A 137 65 0.3421 0.4745 1.0000 2.95e-41 5e7k:71, 5e81:71, 5el4:71, 5el5:71, 5el6:71, 5el7:71, 6gsl:71, 6gsl:79, 5hau:1C, 5hau:2C, 5ib7:71, 5ib8:71, 5ibb:71, 5j8b:C, 6qnq:71, 6qnr:71, 6qnr:79, 4v4i:A, 4v4j:A, 2vpl:C, 4wpo:AC, 4wpo:CC, 4wqf:AC, 4wqf:CC, 4wqu:AC, 4wqu:CC, 4wqy:AC, 4wqy:CC, 4wu1:71, 4wu1:79, 4wzd:71, 4wzd:79
11 2vpl:A 137 50 0.2211 0.3066 0.8400 5.82e-21 5e7k:71, 5e81:71, 5el4:71, 5el5:71, 5el6:71, 5el7:71, 6gsl:71, 6gsl:79, 5hau:1C, 5hau:2C, 5ib7:71, 5ib8:71, 5ibb:71, 5j8b:C, 6qnq:71, 6qnr:71, 6qnr:79, 4v4i:A, 4v4j:A, 2vpl:C, 4wpo:AC, 4wpo:CC, 4wqf:AC, 4wqf:CC, 4wqu:AC, 4wqu:CC, 4wqy:AC, 4wqy:CC, 4wu1:71, 4wu1:79, 4wzd:71, 4wzd:79
12 6c5l:BC 120 60 0.3105 0.4917 0.9833 7.30e-37 6c5l:DC, 4v5j:BC, 4v5j:DC, 4v7j:AC, 4v7j:BC, 4v7k:AC, 4v7k:BC, 4v8n:BC, 4v8n:DC, 4v8x:BC, 4v8x:DC
13 6c5l:BC 120 51 0.1947 0.3083 0.7255 1.76e-14 6c5l:DC, 4v5j:BC, 4v5j:DC, 4v7j:AC, 4v7j:BC, 4v7k:AC, 4v7k:BC, 4v8n:BC, 4v8n:DC, 4v8x:BC, 4v8x:DC
14 4wzo:71 93 52 0.2316 0.4731 0.8462 1.70e-22
15 4wzo:71 93 62 0.1842 0.3763 0.5645 2.85e-12
16 4v4n:AA 216 199 0.3368 0.2963 0.3216 9.03e-20 4v6u:BA
17 1u63:A 214 200 0.3368 0.2991 0.3200 3.57e-18 1i2a:A, 1u63:C
18 7nhk:F 132 71 0.1632 0.2348 0.4366 2.60e-16
19 7nhk:F 132 48 0.1158 0.1667 0.4583 2.84e-07
20 4d5y:u 210 198 0.3211 0.2905 0.3081 1.11e-15 4d67:u, 4ujc:Bu, 4ujd:Au, 4uje:Cu, 4v5z:B5
21 6bu8:03 134 64 0.1474 0.2090 0.4375 1.01e-14 7jsz:a, 7jt3:a, 7k50:a, 7k51:a, 7k52:a, 7k53:a, 7k54:a, 7k55:a, 7lv0:a, 7n2c:LA, 6ofx:a, 6og7:a, 6ogf:a, 6ogg:a, 6ogi:a, 8peg:a, 8pkl:a, 7qg8:C, 7qgh:C, 7qgn:C, 7qgr:C, 8r3v:a2, 8rcl:a2, 8rcm:a2, 7ss9:a, 7ssd:a, 7ssl:a, 7sso:a, 7ssw:a, 7st2:a, 7st7:a, 7tos:L1, 7ug7:LA, 5uyl:03, 5uym:03, 5uyn:03, 5uyp:03, 5uyq:03, 8vs9:L1, 8vsa:L1, 6wd0:a, 6wd1:a, 6wd2:a, 6wd3:a, 6wd4:a, 6wd5:a, 6wd6:a, 6wd7:a, 6wd8:a, 6wd9:a, 6wda:a, 6wdb:a, 6wdc:a, 6wdd:a, 6wde:a, 6wdf:a, 6wdg:a, 6wdh:a, 6wdi:a, 6wdj:a, 6wdk:a, 6wdl:a, 6wdm:a, 6wnt:a, 6wnv:a, 6wnw:a
22 6bu8:03 134 56 0.1684 0.2388 0.5714 3.06e-10 7jsz:a, 7jt3:a, 7k50:a, 7k51:a, 7k52:a, 7k53:a, 7k54:a, 7k55:a, 7lv0:a, 7n2c:LA, 6ofx:a, 6og7:a, 6ogf:a, 6ogg:a, 6ogi:a, 8peg:a, 8pkl:a, 7qg8:C, 7qgh:C, 7qgn:C, 7qgr:C, 8r3v:a2, 8rcl:a2, 8rcm:a2, 7ss9:a, 7ssd:a, 7ssl:a, 7sso:a, 7ssw:a, 7st2:a, 7st7:a, 7tos:L1, 7ug7:LA, 5uyl:03, 5uym:03, 5uyn:03, 5uyp:03, 5uyq:03, 8vs9:L1, 8vsa:L1, 6wd0:a, 6wd1:a, 6wd2:a, 6wd3:a, 6wd4:a, 6wd5:a, 6wd6:a, 6wd7:a, 6wd8:a, 6wd9:a, 6wda:a, 6wdb:a, 6wdc:a, 6wdd:a, 6wde:a, 6wdf:a, 6wdg:a, 6wdh:a, 6wdi:a, 6wdj:a, 6wdk:a, 6wdl:a, 6wdm:a, 6wnt:a, 6wnv:a, 6wnw:a
23 1mzp:A 217 193 0.3000 0.2627 0.2953 2.75e-13 8hku:AL1P, 8hky:AL1P, 8hkz:AL1P, 8hl1:AL1P, 8hl2:AL1P, 8hl3:AL1P, 8hl4:AL1P, 8hl5:AL1P, 4v49:B5, 4v4a:B5, 4v4g:B7, 4v4g:D7, 4v4g:F7, 4v4g:H7, 4v4g:J7, 4v65:BZ, 4v66:BZ
24 3j3v:5 120 60 0.1421 0.2250 0.4500 3.12e-12 3j3w:5
25 3j3v:5 120 51 0.1211 0.1917 0.4510 1.60e-05 3j3w:5
26 6ywe:e 242 187 0.3000 0.2355 0.3048 6.03e-12 6yws:e
27 4v3p:LA 216 194 0.2789 0.2454 0.2732 1.32e-09 4v7e:Cz
28 8v9j:K 102 63 0.1421 0.2647 0.4286 1.81e-09 8v9k:K
29 8v9j:K 102 59 0.1368 0.2549 0.4407 2.20e-07 8v9k:K
30 8brm:Ln 211 193 0.2526 0.2275 0.2487 1.77e-07 8br8:Ln, 8bsi:Ln, 8bsj:Ln, 8btd:Ln, 8btr:Ln
31 8any:z 252 160 0.1947 0.1468 0.2313 9.47e-06 7a5k:n, 7qi5:z, 7qi6:z
32 5e7k:79 57 34 0.1105 0.3684 0.6176 2.91e-05 5e81:79, 5el6:79, 5el7:79, 5ibb:79
33 5e7k:79 57 59 0.1316 0.4386 0.4237 1.48e-04 5e81:79, 5el6:79, 5el7:79, 5ibb:79
34 4v6w:Cz 217 194 0.2684 0.2350 0.2629 3.06e-05 6xu6:Cz, 6xu7:Cz, 6xu8:Cz
35 7a01:42 217 196 0.2526 0.2212 0.2449 0.006 5aj0:Au, 8bhf:l1, 8btk:Bv, 6d90:K, 6d9j:K, 8fku:BB, 8fkv:BB, 8fkw:BB, 8fkx:BB, 8fky:BB, 8fl2:BB, 8fl3:BB, 8fl4:BB, 8g5y:Lz, 8g5z:Lz, 8g60:Lz, 8g61:Lz, 8g6j:Lz, 6gz3:Au, 6gz4:Au, 6gz5:Au, 6hcf:u3, 6hcj:w3, 6hcm:u3, 6hcq:w3, 8idy:t, 8ifd:2l, 8ife:2l, 8inf:q, 6ip5:2l, 3j7r:z, 5lks:Lz, 7ls1:L1, 7ls2:L1, 6mtb:u, 6mtc:u, 6mtd:u, 7nwg:w3, 7o7y:Bv, 7o7z:Bv, 7o80:Bv, 7o81:Bv, 8ohd:Lz, 8oj0:Lz, 8oj5:Lz, 8oj8:Lz, 6olg:Au, 8p2k:Bv, 6p5i:AK, 6p5j:AK, 6p5k:AK, 6p5n:AK, 8q87:Bv, 7qgg:Cz, 6qzp:Lz, 6sgc:B, 5t2c:l, 4ug0:Lz, 4v6x:Cz, 8xsx:Lz, 6y6x:Lz, 6z6l:Lz, 6z6m:Lz, 6z6n:Lz, 7zjw:Lx, 6zm7:Lz, 6zme:Lz, 6zmi:Lz, 6zmo:Lz, 6zvk:42
36 6ywx:e 150 61 0.1000 0.1267 0.3115 0.008 6ywy:e
37 8pv4:Lr 214 193 0.2368 0.2103 0.2332 0.074 8i9r:Lq, 8i9t:Lq, 8i9v:Lq, 8i9w:Lq, 8i9x:Lq, 8i9y:Lq, 8i9z:Lq, 8ia0:Lq, 8pv6:Lr, 8pv8:Lt, 8pvk:Lr
38 4v8m:BJ 214 193 0.2053 0.1822 0.2021 0.074
39 4fgl:D 233 97 0.1421 0.1159 0.2784 0.36 5buc:A, 5buc:B, 2bzs:A, 2bzs:B, 4fgj:A, 4fgj:B, 4fgk:A, 4fgk:B, 4fgl:A, 4fgl:B, 4fgl:C, 3fw1:A, 3g5m:A, 3g5m:B, 3gam:A, 3gam:B, 4gqi:A, 4gqi:B, 4gr9:A, 4gr9:B, 5lbt:A, 5lbt:B, 5lbu:A, 5lbu:B, 5lbw:A, 5lbw:B, 5lby:A, 5lby:B, 5lbz:A, 5lbz:B, 3nfr:A, 3nfr:B, 3nhf:A, 3nhf:B, 3nhj:A, 3nhj:B, 3nhk:A, 3nhk:B, 3nhl:A, 3nhl:B, 3nhp:A, 3nhp:B, 3nhr:A, 3nhr:B, 3nhs:A, 3nhs:B, 3nhu:A, 3nhu:B, 3nhw:A, 3nhw:B, 3nhy:A, 3nhy:B, 3o2n:A, 3o2n:B, 7o4d:A, 7o4d:B, 3o73:A, 3o73:B, 3ovm:A, 3ovm:B, 3owh:A, 3owh:B, 3owx:A, 3owx:B, 3ox1:A, 3ox1:B, 3ox2:A, 3ox2:B, 3ox3:A, 3ox3:B, 2qmy:A, 2qmy:B, 2qmz:A, 2qmz:B, 4qod:A, 4qod:B, 4qoe:A, 4qoe:B, 4qof:A, 4qof:B, 4qog:A, 4qog:B, 4qoh:A, 4qoh:B, 4qoi:A, 4qoi:B, 4qoj:A, 4qoj:B, 1qr2:A, 1qr2:B, 2qr2:A, 2qr2:B, 2qwx:A, 2qwx:B, 2qx4:A, 2qx4:B, 2qx6:A, 2qx6:B, 2qx8:A, 2qx8:B, 2qx9:A, 2qx9:B, 1sg0:A, 1sg0:B, 3te7:A, 3te7:B, 3tem:A, 3tem:B, 3tzb:A, 3tzb:B, 3tzb:C, 3tzb:D, 4u7f:A, 4u7f:B, 4u7g:A, 4u7g:B, 4u7h:A, 4u7h:B, 3uxe:A, 3uxe:B, 3uxh:A, 3uxh:B, 4xdg:A, 4xdg:B, 4xdh:A, 4xdh:B, 1xi2:A, 1xi2:B, 4zvk:A, 4zvk:B, 4zvl:A, 4zvl:B, 4zvm:A, 4zvm:B, 4zvn:A, 4zvn:B, 1zx1:A, 1zx1:B
40 8i9p:CB 269 67 0.1316 0.0929 0.3731 0.64 8i9r:CB, 8i9t:CB, 8i9v:CB, 8i9w:CB, 8i9x:CB, 8i9y:CB, 8i9z:CB, 8ia0:CB, 8pv1:CB, 8pv3:CB, 8pv4:CB, 8pv7:CB, 8pvk:CB, 6rxt:UZ, 6rxu:UZ, 6rxv:UZ, 6rxy:UZ, 6rxz:UZ
41 8c3a:l1 217 192 0.2316 0.2028 0.2292 0.87 8c3a:L1, 8cq7:l1, 8cq7:L1, 8cqw:l1, 8cqw:L1, 8cre:l1, 8cre:L1, 8oeq:l1, 8oeq:L1
42 7kx9:A 734 43 0.0895 0.0232 0.3953 1.1 7kx7:A, 7yfq:A, 7yg6:A
43 6l2n:A 217 55 0.1053 0.0922 0.3636 2.6 5iff:A, 5iff:B, 6l2n:B, 6l2o:A, 6l2o:B, 6m3l:A, 3waz:A, 3waz:B
44 5jpq:k 182 41 0.0947 0.0989 0.4390 3.2 5oql:Q
45 8cmy:C 445 89 0.1211 0.0517 0.2584 5.5 8cmy:M, 8cmy:G, 8cmy:I, 8cmy:K, 8cmy:O, 7yyo:A, 7yyo:C, 7yyo:E, 7yyo:G, 7yyo:I, 7yyo:K, 7yyo:M, 7yyo:O
46 5v1x:D 447 105 0.1421 0.0604 0.2571 7.5 5v12:F, 5v12:B, 5v1x:C, 5v1x:A, 5v1x:B
47 8bjd:A 208 65 0.1000 0.0913 0.2923 9.3 8bje:A, 8bk5:A, 2vcd:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218