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●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
KVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPE
TKQEKKQRLLARAEKKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVH
RKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG

The query sequence (length=231) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 4v6x:CG 246 241 1.0000 0.9390 0.9585 3.45e-167 7a01:V2, 8a3d:n, 5aj0:AG, 8b5l:G, 8b6c:G, 9bdl:AL08, 9bdn:AL08, 9bdp:AL08, 7bhp:LG, 8bhf:p3, 8bpo:G2, 8btk:BG, 7cpu:LG, 7cpv:LG, 4d5y:G, 4d67:G, 6d90:G, 6d9j:G, 9f1b:BG, 9f1c:BG, 9f1d:BG, 7f5s:LG, 8fkp:SE, 8fkq:SE, 8fkr:SE, 8fks:SE, 8fkt:SE, 8fku:SE, 8fkv:SE, 8fkw:SE, 8fkx:SE, 8fky:SE, 8fkz:SE, 8fl2:SE, 8fl3:SE, 8fl4:SE, 8fl6:SE, 8fl7:SE, 8fl9:SE, 8fla:SE, 8flb:SE, 8flc:SE, 8fld:SE, 8fle:SE, 8flf:SE, 6frk:G, 6ftg:G, 6fti:G, 6ftj:G, 8g5y:LG, 8g5z:LG, 8g60:LG, 8g61:LG, 8g6j:LG, 8glp:LG, 6gz3:AG, 6gz4:AG, 6gz5:AG, 6hcf:G3, 6hcj:G3, 6hcm:G3, 6hcq:G3, 8idt:G, 8idy:G, 8ie3:G, 8ifd:2B, 8ife:2B, 8ine:G, 8inf:G, 8ink:G, 6ip5:2B, 6ip6:2B, 6ip8:2B, 8ipd:G, 8ipx:G, 8ipy:G, 8ir1:G, 8ir3:G, 3j7o:G, 3j7p:G, 3j7q:G, 3j7r:G, 3j92:G, 3jag:G, 3jah:G, 3jai:G, 3jaj:G, 3jan:G, 8jdj:M, 8jdk:M, 8jdl:M, 8jdm:M, 8k2c:LG, 5lks:LG, 6lqm:G, 6lsr:G, 6lss:G, 7ls1:B1, 7ls2:B1, 6lu8:G, 5lzs:G, 5lzt:G, 5lzu:G, 5lzv:G, 5lzw:G, 5lzx:G, 5lzy:G, 5lzz:G, 7mdz:G, 6mtb:G, 6mtc:G, 6mtd:G, 6mte:G, 7nfx:G, 7nwg:G3, 7nwh:G, 7nwi:G, 7o7y:BG, 7o7z:BG, 7o80:BG, 7o81:BG, 7obr:G, 8ohd:LG, 8oj0:LG, 8oj5:LG, 8oj8:LG, 6ole:I, 6olf:I, 6olg:AG, 6oli:I, 6olz:AG, 6om0:I, 6om7:I, 7ow7:n, 7oya:G1, 7oyb:G1, 7oyc:G1, 7oyd:G, 8p2k:BG, 6p5i:AG, 6p5j:AG, 6p5k:AG, 6p5n:AG, 8q7z:BG, 8q87:BG, 8qfd:G, 7qgg:I, 8qoi:LG, 7qvp:MG, 7qvp:LG, 7qwq:G, 7qwr:G, 7qws:G, 6qzp:LG, 6r5q:G, 6r6g:G, 6r6p:G, 6r7q:G, 8rjb:G, 8rjc:G, 8rjd:G, 8scb:G, 6sgc:G2, 6swa:G, 5t2c:n, 6t59:G3, 7tm3:G, 7toq:AL08, 7tor:AL08, 7tut:G, 7ucj:G, 7uck:G, 4ug0:LG, 4ujc:BG, 4ujd:AG, 4uje:CG, 4v5z:Bf, 6w6l:I, 6xa1:LG, 7xnx:LG, 7xny:LG, 8xsx:LG, 8xsy:LG, 8xsz:LG, 6y0g:LG, 8y0w:LG, 8y0x:LG, 6y2l:LG, 6y57:LG, 6y6x:LG, 8yoo:LG, 8yop:LG, 6z6l:LG, 6z6m:LG, 6z6n:LG, 7zjw:LJ, 7zjx:LJ, 6zm7:LG, 6zme:LG, 6zmi:LG, 6zmo:LG, 6zvk:V2
2 4v6w:CG 241 241 0.7013 0.6722 0.6722 2.79e-118 6xu6:CG, 6xu7:CG, 6xu8:CG
3 9bh5:CG 221 221 0.6147 0.6425 0.6425 2.59e-101 9cai:CG
4 4v7e:CG 237 236 0.6104 0.5949 0.5975 7.20e-100 8ip8:AA, 8ipa:AA, 8ipb:AA, 8jiv:CG, 4v3p:LH
5 8c3a:p 238 216 0.5801 0.5630 0.6204 1.45e-97 8c3a:BC, 8cq7:p, 8cq7:BC, 8cqw:p, 8cqw:BC, 8cre:p, 8cre:BC, 8oeq:p, 8oeq:BC, 7pzy:p, 7q08:p, 7q0f:p, 7q0p:p, 7q0r:p, 8q5i:p
6 7r81:J1 236 229 0.6017 0.5890 0.6070 6.27e-97
7 8eug:G 230 229 0.5974 0.6000 0.6026 7.34e-97 8esq:G, 8esr:G, 8etc:G, 8etg:G, 8eth:G, 8eti:G, 8etj:G, 8eui:G, 8eup:G, 8euy:G, 8ev3:G
8 7olc:LG 235 229 0.5974 0.5872 0.6026 1.24e-95 8i9p:LG, 8i9r:LG, 8i9t:LG, 8i9v:LG, 8i9w:LG, 8i9x:LG, 8i9y:LG, 8i9z:LG, 8ia0:LG, 7old:LG, 8oo0:LG, 8pv1:LG, 8pv2:LG, 8pv3:LG, 8pv4:LG, 8pv5:LG, 8pv6:LG, 8pv7:LG, 8pv8:LG, 8pvk:LG, 8pvl:LG, 7z3n:LG, 7z3o:LG
9 8azw:c 233 233 0.5758 0.5708 0.5708 1.40e-95 8b2l:c3, 7qiw:J, 7qiz:J
10 8aaf:p 233 225 0.5714 0.5665 0.5867 6.09e-93 8agt:p, 8agu:p, 8agv:p, 8agw:p, 8agx:p, 8agz:p, 5apn:G, 5apo:G, 7azy:b, 7b7d:LJ, 8bip:LG, 8bjq:LG, 8bn3:L8, 8bqd:AA, 8bqx:AA, 7bt6:G, 7btb:G, 6c0f:G, 6cb1:G, 8ccs:KK, 8cdl:KK, 8cdr:KK, 8ceh:KK, 8cf5:KK, 8cg8:KK, 8cgn:KK, 8civ:KK, 8cku:KK, 8cmj:KK, 5dat:L8, 5dat:l8, 5dc3:L8, 5dc3:l8, 5dge:L8, 5dge:l8, 5dgf:L8, 5dgf:l8, 5dgv:L8, 5dgv:l8, 8e5t:G, 6elz:G, 6em1:G, 6em3:G, 6em4:G, 6em5:G, 8eub:AG, 8evp:AG, 8evq:AG, 8evr:AG, 8evs:AG, 8evt:AG, 8ewb:AG, 8ewc:AG, 5fci:L8, 5fci:l8, 5fcj:L8, 5fcj:l8, 6ft6:G, 5gak:K, 6gq1:G, 6gqb:G, 6gqv:G, 5h4p:G, 6hd7:K, 8hfr:Hj, 6hhq:p, 6hhq:CJ, 5i4l:L8, 5i4l:l8, 6i7o:AA, 6i7o:XA, 3j6x:L8, 3j6y:L8, 3j77:L8, 3j78:L8, 3jct:G, 5jcs:G, 5juo:L, 5jup:L, 5jus:L, 5jut:L, 5juu:L, 8k2d:LG, 8k82:LG, 5lyb:L8, 5lyb:l8, 5m1j:G5, 6m62:G, 5mc6:AA, 5mei:p, 5mei:CJ, 7mpi:AG, 7mpj:AG, 6n8j:G, 6n8k:G, 6n8l:G, 6n8m:J, 6n8n:J, 6n8o:J, 7n8b:AG, 7nac:G, 5ndg:L8, 5ndg:l8, 5ndv:L8, 5ndv:l8, 5ndw:L8, 5ndw:l8, 7nrc:LJ, 7nrd:LJ, 5obm:L8, 5obm:l8, 7of1:G, 7oh3:G, 7ohp:G, 7ohq:G, 7ohr:G, 7ohs:G, 7ohu:G, 7ohv:G, 7ohw:G, 7ohx:G, 7ohy:G, 6oig:G, 5on6:p, 5on6:CJ, 7osa:eL8, 7osm:eL8, 8p8m:LL, 8p8n:LL, 8p8u:LL, 8pfr:LL, 6q8y:AA, 6qik:H, 6qt0:H, 6qtz:H, 7r6q:G, 7r7a:G, 6r84:K, 6r86:K, 6r87:K, 6ri5:H, 7rr5:LG, 6rzz:H, 6s05:H, 6s47:AJ, 6snt:n, 6sv4:AA, 6sv4:XA, 6sv4:zA, 6t4q:LG, 5t62:J, 5t6r:J, 6t7i:LG, 6t7t:LG, 6t83:Gy, 6t83:Ja, 5tbw:p, 5tbw:CJ, 6tb3:AA, 5tga:L8, 5tga:l8, 5tgm:L8, 5tgm:l8, 6tnu:AA, 7too:AL08, 7top:AL08, 7u0h:G, 4u3m:L8, 4u3m:l8, 4u3n:L8, 4u3n:l8, 4u3u:L8, 4u3u:l8, 4u4n:L8, 4u4n:l8, 4u4o:L8, 4u4o:l8, 4u4q:L8, 4u4q:l8, 4u4r:L8, 4u4r:l8, 4u4u:L8, 4u4u:l8, 4u4y:L8, 4u4y:l8, 4u4z:L8, 4u4z:l8, 4u50:L8, 4u50:l8, 4u51:L8, 4u51:l8, 4u52:L8, 4u52:l8, 4u53:L8, 4u53:l8, 4u55:L8, 4u55:l8, 4u56:L8, 4u56:l8, 4u6f:L8, 4u6f:l8, 7ug6:G, 7uoo:G, 7uqb:G, 7uqz:G, 7v08:G, 4v4b:BG, 4v6i:BH, 4v7h:BG, 4v7r:BH, 4v7r:DH, 4v88:BG, 4v88:DG, 4v8t:G, 4v8y:BG, 4v8z:BG, 8v83:G, 8v84:G, 8v87:G, 4v91:G, 6woo:G, 6xiq:G, 6xir:G, 8y0u:LG, 6ylg:G, 6ylh:G, 6ylx:G, 6yly:G, 5z3g:K, 7z34:G, 6z6j:LG, 6z6k:LG, 7zpq:BG, 7zrs:BG, 7zs5:BI, 7zuw:BG, 7zux:EG, 7zw0:LK
11 5it7:GG 233 235 0.5801 0.5751 0.5702 1.14e-91 6uz7:AG
12 4v8p:BF 231 231 0.5628 0.5628 0.5628 2.77e-90 4v8p:CF, 4v8p:EF, 4v8p:GF
13 5xxb:G 233 235 0.5368 0.5322 0.5277 9.20e-80
14 6zj3:LV 238 209 0.4848 0.4706 0.5359 1.11e-78
15 3j79:J 229 234 0.5065 0.5109 0.5000 1.05e-74 3jbn:AJ, 3jbo:AJ, 3jbp:AJ, 8tpu:AJ, 5umd:J
16 4v8m:Bx 240 222 0.4545 0.4375 0.4730 4.54e-69 8ova:Bx, 8ove:Bx, 5t5h:x
17 8rxh:LG 241 222 0.4416 0.4232 0.4595 5.14e-68 8a3w:G, 8a98:G, 6az3:G, 3jcs:G, 8ovj:G, 8rxx:LG, 5t2a:v
18 5xy3:G 174 185 0.3766 0.5000 0.4703 9.74e-59
19 8fru:G 197 192 0.3983 0.4670 0.4792 6.80e-58 8br8:LI, 8brm:LI, 8bsi:LI, 8bsj:LI, 8btd:LI, 8btr:LI, 7pwg:G, 7pwo:G2
20 6zu5:LG0 202 170 0.3074 0.3515 0.4176 3.37e-44
21 7qep:L8 197 181 0.3203 0.3756 0.4088 1.62e-41
22 8p5d:LG0 199 160 0.2641 0.3065 0.3812 3.52e-40 8p60:LG0, 8p60:KG0, 7qca:LG0
23 6rm3:LG0 195 158 0.2641 0.3128 0.3861 3.07e-35
24 6q8u:C 122 111 0.1818 0.3443 0.3784 3.16e-12 4bw0:B, 4c4w:C, 4c4w:G, 5fj4:C, 5fj4:G, 5g4u:C, 5g4u:D, 5g4u:G, 5g4u:H, 5g4u:K, 5g4u:L, 5g4v:C, 5g4v:D, 5g4v:G, 5g4v:H, 6hct:C, 6hct:D, 6hct:G, 6q8u:D, 1rlg:A, 1rlg:B
25 6k0a:I 116 111 0.1602 0.3190 0.3333 1.76e-11 6k0a:J, 6k0b:I, 6k0b:J, 1sds:A, 1sds:C, 1sds:B
26 5y7m:A 125 56 0.1126 0.2080 0.4643 1.61e-10 4by9:G, 4by9:J, 4by9:D, 4by9:M, 5dcv:A, 5dcv:C, 3hax:D, 3hay:D, 3hjw:C, 2hvy:D, 5jb3:3, 5jbh:3, 3lwo:C, 3lwp:C, 3lwq:C, 3lwr:C, 3lwv:C, 3nmu:G, 3nmu:C, 3nvi:B, 3nvi:D, 3nvk:E, 3nvk:H, 7ozq:B, 7ozq:D, 7ozq:C, 7ozq:A, 6skf:BH, 6skf:BI, 6skg:BH, 6skg:BI, 6sw9:3, 6swc:3, 6swe:3, 6th6:BH, 6th6:BI, 6tph:A, 4v4n:B3, 4v4n:AG, 4v6u:A3, 4v6u:BG, 4v6u:B4, 5xtm:A, 5xtm:C, 5y7m:C, 7zag:3, 7zah:3, 7zai:3, 7zhg:3
27 6tmf:b 123 56 0.1169 0.2195 0.4821 1.65e-10
28 8hku:L7A1 123 94 0.1515 0.2846 0.3723 6.63e-10 8hku:L7A2, 8hkv:L7A1, 8hkv:L7A2, 8hkx:SL7A, 8hky:L7A1, 8hky:L7A2, 8hky:SL7A, 8hkz:L7A1, 8hkz:L7A2, 8hkz:SL7A, 8hl1:SL7A, 8hl1:L7A1, 8hl1:L7A2, 8hl2:L7A1, 8hl2:L7A2, 8hl2:SL7A, 8hl3:L7A1, 8hl3:L7A2, 8hl3:SL7A, 8hl4:L7A1, 8hl4:L7A2, 8hl4:SL7A, 8hl5:L7A1, 8hl5:L7A2, 8hl5:SL7A, 8wkp:SL7A, 8wq2:SL7A, 8wq4:SL7A
29 7r6k:G 52 33 0.0952 0.4231 0.6667 3.84e-09
30 7r6k:G 52 36 0.0519 0.2308 0.3333 1.1
31 5gin:C 122 68 0.1126 0.2131 0.3824 6.36e-09 5gin:D, 5gin:L, 5gio:C, 5gio:D, 5gio:L, 5gip:C, 5gip:D, 5gip:M, 5gip:N, 3id5:C, 3id5:G, 5jpq:U, 5jpq:V, 3pla:C, 3pla:D, 3pla:L
32 3siv:A 128 57 0.0909 0.1641 0.3684 8.23e-08 6ah0:M, 6ahd:M, 1e7k:A, 1e7k:B, 8h6e:4E, 8h6j:4E, 8h6k:4E, 8h6l:4E, 7mq8:SE, 7mq8:SF, 7mq9:SE, 7mq9:SF, 7mqa:SE, 7mqa:SF, 5o9z:O, 2ozb:A, 2ozb:D, 8q7n:M, 8qo9:M, 8qoz:M, 8qpa:M, 8qpb:M, 8qpe:M, 6qw6:4D, 6qx9:4D, 8qxd:M, 8qzs:M, 8r08:M, 8r09:M, 8r0a:M, 8r0b:M, 8rm5:M, 3siu:A, 3siu:D, 3siv:D, 3siv:J, 3siv:G, 8y6o:O
33 5oql:V 121 57 0.0866 0.1653 0.3509 6.82e-07 5oql:W, 6rxt:CE, 6rxt:CF, 6rxu:CE, 6rxu:CF, 6rxv:CE, 6rxv:CF, 6rxx:CE, 6rxx:CF, 6rxy:CE, 6rxy:CF, 6rxz:CE, 6rxz:CF
34 3cc2:F 119 68 0.0909 0.1765 0.3088 7.25e-07 3cc4:F, 3cc7:F, 3cce:F, 3ccj:F, 3ccl:F, 3ccm:F, 3ccq:F, 3ccr:F, 3ccs:F, 3ccu:F, 3ccv:F, 3cd6:F, 3cma:F, 3cme:F, 3cpw:F, 3cxc:F, 3g4s:F, 3g6e:F, 3g71:F, 3i55:F, 3i56:F, 1jj2:F, 1k73:H, 1k8a:H, 1k9m:H, 1kc8:H, 1kd1:H, 1kqs:F, 1m1k:H, 1m90:H, 1n8r:H, 1nji:H, 2otj:F, 2otl:F, 3ow2:F, 1q7y:H, 1q81:H, 1q82:H, 1q86:H, 2qa4:F, 2qex:F, 1qvf:F, 1qvg:F, 1s72:F, 4v9f:F, 1vq4:F, 1vq5:F, 1vq6:F, 1vq7:F, 1vq8:F, 1vq9:F, 1vqk:F, 1vql:F, 1vqm:F, 1vqn:F, 1vqo:F, 1vqp:F, 1w2b:F, 1yhq:F, 1yi2:F, 1yij:F, 1yit:F, 1yj9:F, 1yjn:F, 1yjw:F
35 7v9a:I 134 89 0.1126 0.1940 0.2921 8.69e-07 7bgb:I, 8oue:I, 8ouf:I, 7trc:I
36 2ale:A 132 57 0.0823 0.1439 0.3333 1.19e-06 7ajt:CF, 7ajt:CG, 7aju:CF, 7aju:CG, 7d4i:3G, 7d4i:3H, 7d5s:3G, 7d5s:3H, 7d5t:3G, 7d5t:3H, 7d63:3G, 7d63:3H, 5gan:K, 5gap:K, 3jcm:M, 6ke6:3G, 6ke6:3H, 6lqp:3G, 6lqp:3H, 6lqq:3G, 6lqq:3H, 6lqr:3G, 6lqr:3H, 6lqs:3G, 6lqs:3H, 6lqt:3G, 6lqt:3H, 6lqu:3G, 6lqu:3H, 6lqv:3G, 6lqv:3H, 6nd4:e, 6nd4:f, 5nrl:K, 4nut:A, 7suk:SE, 7suk:SF, 5tzs:f, 5wlc:SE, 5wlc:SF, 5wyj:3G, 5wyj:3H, 5wyk:3G, 5wyk:3H, 6zqa:CF, 6zqb:CF, 6zqb:CG, 6zqc:CF, 6zqc:CG, 6zqd:CF, 6zqd:CG, 6zqe:CF, 6zqe:CG, 5zwm:M, 5zwo:M
37 4bts:AU 124 60 0.0823 0.1532 0.3167 0.038 4bts:BU, 4bts:CU, 4bts:DU, 4v5o:AU, 4v5o:BU
38 5xyi:M 103 69 0.0823 0.1845 0.2754 0.98
39 8auv:C 117 54 0.0693 0.1368 0.2963 1.3 8b2l:C1
40 2cs2:A 134 54 0.0606 0.1045 0.2593 2.6
41 5v8f:E 422 167 0.1775 0.0972 0.2455 2.9 6wgc:E, 6wgg:E, 6wgi:E
42 4v7e:BM 123 54 0.0693 0.1301 0.2963 4.6 8r57:M
43 5zr1:E 460 61 0.0823 0.0413 0.3115 5.6 7mca:E, 6rqc:E, 7tjf:E
44 6zj3:L1 50 16 0.0390 0.1800 0.5625 5.7
45 2n8a:A 214 54 0.0606 0.0654 0.2593 6.4 4av1:D, 4av1:B, 2l30:A, 2l31:A, 3od8:D, 3od8:F, 3oda:D, 3oda:F, 3odc:A, 3odc:B, 3ode:A, 3ode:B, 7s81:N, 7s81:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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