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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KVVDRLDSQPSAAFEQTKQVYTFSRYILGPHRAVVAPVAMDPSEKEVVLRAVYRQVFGNAYIMEEERAELRVMESQFLLG
ELSVKELVRALAKSSTYKVRFFEGAVQYRFIELCFKHLLGRAPDNHEEIAVHMRKYQQEGYDAEIDSYLDAGEYDNVFGD
DTVPFLRFRGVYTPCDSFNRQCALQGGWANSDKAMGGAALSGYNGSDGRQMSTMIGNYISGKPIPYEKVAADTPLKSTAP
NWYARPNPALAPQPAYVSAKEIAELRSRVSKLEAAWSVAVKQSAAAKDTVETWRAAAKEMAAMRGISPMGEAYFGGIAQK
VDNGALAQLGNKASSYKKYLYAIETDEVSRLEVDLEEAKGQLRVLEAAMAKSTPMTRTAE

The query sequence (length=380) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7y4l:bH 407 380 1.0000 0.9337 1.0000 0.0 7ezx:bB, 7ezx:bM, 6kgx:b8, 6kgx:bA, 7y4l:b4, 7y5e:bJ, 7y5e:bM, 7y7a:b3, 7y7a:bC, 7y7a:bV, 7y7a:bp
2 5y6p:B2 374 382 0.5500 0.5588 0.5471 1.22e-147 5y6p:b3
3 7y4l:z8 463 188 0.2526 0.2073 0.5106 7.06e-61 7ezx:zJ, 7ezx:zL, 6kgx:zE, 6kgx:zG, 7y4l:zF, 7y5e:zK, 7y5e:zF, 7y7a:zT, 7y7a:zQ, 7y7a:zb, 7y7a:z6
4 5y6p:a8 362 173 0.2368 0.2486 0.5202 2.49e-57 5y6p:a9
5 7ezx:d4 297 275 0.2816 0.3603 0.3891 2.50e-50 7ezx:dD, 6kgx:d9, 6kgx:dJ, 7y4l:d5, 7y4l:dJ, 7y5e:dD, 7y5e:dQ, 7y7a:d2, 7y7a:dc, 7y7a:dF, 7y7a:dM
6 5y6p:dy 303 152 0.1868 0.2343 0.4671 6.92e-49 5y6p:dz
7 7ezx:MC 280 142 0.1868 0.2536 0.5000 1.61e-46 7ezx:ME, 7y4l:ZG, 7y4l:MG, 7y5e:ZI, 7y5e:MI, 7y7a:MJ, 7y7a:Mk, 7y7a:ZJ, 7y7a:Zk
8 7ezx:e2 248 209 0.2500 0.3831 0.4545 4.38e-46 7ezx:eR, 6kgx:e3, 6kgx:eD, 7y4l:eK, 7y4l:e1, 7y5e:eA, 7y5e:e7, 7y7a:eD, 7y7a:e5, 7y7a:eg, 7y7a:ei
9 7ezx:O3 375 148 0.1789 0.1813 0.4595 5.36e-39 7ezx:OO, 6kgx:b1, 6kgx:o1, 6kgx:b4, 6kgx:o4, 7liz:A, 7y4l:Y7, 7y4l:b7, 7y5e:YP, 7y5e:bP, 7y7a:YL, 7y7a:bL, 7y7a:bU, 7y7a:YU
10 5y6p:24 331 156 0.1895 0.2175 0.4615 3.60e-36 5y6p:X5, 5y6p:S8, 5y6p:X9, 5y6p:aX, 5y6p:bX
11 5y6p:ex 233 158 0.1842 0.3004 0.4430 2.89e-35 5y6p:ew, 5y6p:fz, 5y6p:fd
12 7ezx:X1 324 156 0.1842 0.2160 0.4487 1.30e-34 7ezx:X7, 7ezx:X9, 7ezx:XF, 7ezx:XI, 7ezx:XK, 6kgx:X2, 6kgx:X6, 6kgx:X7, 6kgx:XB, 6kgx:XF, 6kgx:XI, 7y4l:XB, 7y4l:XC, 7y4l:XD, 7y4l:XE, 7y4l:X2, 7y4l:X6, 7y5e:XE, 7y5e:XG, 7y5e:XH, 7y5e:XO, 7y5e:X1, 7y5e:X4, 7y7a:X1, 7y7a:X4, 7y7a:X8, 7y7a:XI, 7y7a:XK, 7y7a:XP, 7y7a:XR, 7y7a:XS, 7y7a:Xe, 7y7a:Xj, 7y7a:Xl, 7y7a:Xn
13 8tpj:A 210 150 0.1316 0.2381 0.3333 4.06e-17
14 5y6p:aW 228 128 0.0974 0.1623 0.2891 1.22e-15 5y6p:14, 5y6p:W5, 5y6p:R8, 5y6p:W9, 5y6p:bW
15 8uhe:K 593 140 0.1342 0.0860 0.3643 9.05e-15
16 8uhe:K 593 123 0.1026 0.0658 0.3171 1.63e-12
17 2e2r:A 227 48 0.0395 0.0661 0.3125 3.0 6a6k:A, 6a6k:B, 6a6k:C, 2ewp:A, 2ewp:B, 2ewp:C, 2ewp:D, 2ewp:E, 2gp7:A, 2gpo:A, 2gpp:A, 2gpp:B, 2gpu:A, 2gpv:A, 2gpv:B, 2gpv:C, 2gpv:D, 2gpv:E, 2gpv:F, 6i61:A, 6i62:A, 6i63:A, 6i64:A, 6i65:A, 6i66:A, 6i67:A, 6k3n:A, 6knr:A, 6knr:B, 1kv6:A, 1kv6:B, 2p7a:A, 2p7g:A, 2p7z:A, 1s9p:A, 1s9p:B, 1s9p:C, 1s9p:D, 1s9q:A, 1s9q:B, 1tfc:A, 1tfc:B, 1vjb:A, 1vjb:B, 5yso:A, 5yso:B, 5yso:C, 2zas:A, 2zkc:A
18 5h08:A 282 37 0.0368 0.0496 0.3784 3.1
19 1lnl:A 408 50 0.0421 0.0392 0.3200 4.7 1lnl:B, 1lnl:C
20 5juy:B 1234 115 0.0711 0.0219 0.2348 5.3 1cy5:A, 3j2t:A, 3j2t:B, 3j2t:C, 3j2t:D, 3j2t:E, 3j2t:F, 3j2t:G, 3jbt:A, 3jbt:C, 3jbt:E, 3jbt:G, 3jbt:I, 3jbt:K, 3jbt:M, 5juy:A, 5juy:C, 5juy:D, 5juy:E, 5juy:F, 5juy:G, 2p1h:A, 5wve:A, 5wve:C, 5wve:E, 5wve:G, 5wve:I, 5wve:K, 5wve:M, 1z6t:A, 1z6t:B, 1z6t:C, 1z6t:D
21 6enz:A 487 45 0.0395 0.0308 0.3333 6.4 6enz:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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