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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
KVVAVVKLQLPAGKATPAPPVGPALGQHGANIMEFVKAFNAATANMGDAIVPVEITIYADRSFTFVTKTPPASYLIRKAA
GLEKGAHKPGREKVGRITWEQVLEIAKQKMPDLNTTDLEAAARMIAGSARSMGVEVVGAPEVKDA

The query sequence (length=145) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 5d8b:G 147 145 1.0000 0.9864 1.0000 1.78e-103 5a9z:AJ, 5aa0:AJ, 6c5l:BK, 6c5l:DK, 3cjt:B, 3cjt:F, 3cjt:J, 3cjt:N, 5d8b:CB, 6gsl:48, 5hau:1K, 5hau:2K, 5imq:3, 5imr:3, 5j8b:K, 4v4x:BL, 4v4y:BL, 4v4z:BL, 4v5e:BK, 4v5e:DK, 4v5f:BK, 4v5f:DK, 4v5j:BK, 4v5j:DK, 4v5m:BK, 4v5n:BK, 4v67:BK, 4v67:DK, 4v68:BL, 4v6f:DL, 4v9h:BK, 4v9j:BK, 4v9j:DK, 4v9k:BK, 4v9k:DK, 4v9l:BK, 4v9l:DK, 4v9m:BK, 4v9m:DK, 4v9n:BK, 4v9n:DK, 4w29:BK, 4w29:DK, 4w2e:K, 4wpo:AL, 4wpo:CL, 4wqf:AL, 4wqf:CL, 4wqu:AL, 4wqu:CL, 4wqy:AL, 4wqy:CL, 4xej:AL11, 4xej:BL11, 5zlu:f
2 3cjq:B 121 139 0.8207 0.9835 0.8561 9.08e-79 3cjq:E, 3cjq:H
3 3cf5:F 144 141 0.7241 0.7292 0.7447 3.67e-75 3dll:F, 5dm6:F, 5dm7:F, 4io9:F, 4ioa:F, 4ioc:F, 5jvg:F, 3pio:F, 3pip:F, 1sm1:G, 4v49:BG, 4v4a:BG, 4v4g:BJ, 4v4g:DJ, 4v4g:FJ, 4v4g:HJ, 4v4g:JJ, 1xbp:G, 2zjp:F, 2zjq:F, 2zjr:F
4 2jq7:A 134 132 0.6069 0.6567 0.6667 1.90e-63 1mms:A, 1mms:B, 1oln:A, 4v4p:AL, 4v4r:BK, 4v4s:BK, 4v4t:BK
5 6dzi:J 133 132 0.5586 0.6090 0.6136 2.89e-58 6dzp:J, 8fr8:S, 8kab:J, 5o60:J, 5o61:J, 7s0s:K, 8v9j:J, 8v9k:J, 8v9l:J, 7xam:J, 8xz3:J, 7y41:J, 5zeb:J, 5zep:J, 5zet:J
6 3j3v:6 141 127 0.5517 0.5674 0.6299 2.44e-56 7aqc:I, 7aqd:I, 7as8:K, 7as9:K, 7asa:K, 1c04:C, 1hc8:A, 1hc8:B, 3j3w:6, 3j9w:BK, 7o5b:q, 7ope:K, 1qa6:A, 1qa6:B, 7qgu:I, 7qh4:I, 1y39:A, 1y39:B
7 8a57:E 140 134 0.5586 0.5786 0.6045 3.38e-55 8uu8:H
8 4v61:BK 145 136 0.5448 0.5448 0.5809 3.10e-54 5mmi:J, 5mmm:J
9 5ady:I 141 137 0.5586 0.5745 0.5912 1.99e-52 7abz:I, 5afi:I, 5aka:I, 7bl2:I, 7bl3:I, 7bl5:I, 6bu8:11, 7bv8:J, 6by1:CI, 6by1:DI, 6c4i:J, 7cpj:I, 4csu:I, 7d6z:I, 7d80:h, 3deg:H, 6dnc:M, 8fiz:BL, 8fzd:J, 8fze:J, 8fzf:J, 8fzg:J, 8fzh:J, 8fzi:J, 8fzj:J, 8g7p:J, 8g7q:J, 5gad:J, 5gae:J, 5gaf:J, 5gag:J, 5gah:J, 6gwt:I, 6gxm:I, 6gxn:I, 6gxo:I, 6gxp:I, 5h5u:J, 6hrm:I, 6i0y:I, 6i7v:DJ, 6i7v:CJ, 5iqr:I, 5it8:CJ, 5it8:DJ, 3j0d:G, 2j28:I, 3j5l:I, 5j5b:CJ, 5j5b:DJ, 3j7z:I, 5j7l:CJ, 5j7l:DJ, 3j8g:I, 5j88:CJ, 5j88:DJ, 5j8a:CJ, 5j8a:DJ, 3j9y:I, 3j9z:LE, 5j91:CJ, 5j91:DJ, 3ja1:LK, 3jbv:i, 3jcd:I, 3jce:I, 3jcj:H, 3jcn:I, 5jc9:CJ, 5jc9:DJ, 7jsz:i, 5jte:BI, 7jt3:i, 5ju8:BI, 7k50:i, 7k51:i, 7k52:i, 7k53:i, 7k54:i, 7k55:i, 5kcr:1K, 5kcs:1K, 5kps:I, 5kpv:H, 5kpw:H, 5kpx:H, 5l3p:K, 6lkq:Z, 7lv0:i, 5lza:I, 5lzb:I, 5lzc:I, 5lzd:I, 5lze:I, 5lzf:I, 7m5d:I, 5mdv:I, 5mdw:I, 5mdy:I, 5mdz:I, 7n1p:LK, 7n2c:LK, 7n2v:LK, 5nco:J, 5np6:g, 5nwy:V, 7nwt:I, 5o2r:I, 6o9j:6, 6o9k:I, 7oj0:9, 8p16:I, 8p17:I, 8p18:I, 8peg:k, 8phj:6, 6pj6:Q, 7pjs:I, 7pjt:I, 7pju:I, 7pjv:I, 7pjw:I, 7pjx:I, 7pjy:I, 7pjz:I, 8pkl:k, 6q97:I, 6q98:I, 6q9a:I, 7qg8:V, 7qgh:V, 7qgn:V, 7qgr:V, 8qk7:I, 6s0k:J, 7sa4:I, 7ss9:i, 7ssd:i, 7ssl:i, 7ssn:i, 7sso:i, 7ssw:i, 7st2:i, 7st6:i, 7st7:i, 7tos:L11, 4u1u:BI, 4u1u:DI, 4u1v:BI, 4u1v:DI, 4u20:BI, 4u20:DI, 4u24:BI, 4u24:DI, 4u25:BI, 4u25:DI, 4u26:BI, 4u26:DI, 4u27:BI, 4u27:DI, 5u4i:J, 6u48:CJ, 5u9f:11, 5u9g:11, 7ug7:LK, 8upo:Y, 8upr:Y, 8uql:Y, 8uqm:Y, 8uqp:Y, 8ur0:Y, 8urh:Y, 8uri:Y, 8urx:Y, 8ury:Y, 4uy8:I, 5uyk:11, 5uyl:11, 5uym:11, 5uyn:11, 5uyp:11, 5uyq:11, 4v4h:BI, 4v4h:DI, 4v4q:BI, 4v4q:DI, 4v4v:BG, 4v4w:BG, 4v50:BI, 4v50:DI, 4v52:BI, 4v52:DI, 4v53:BI, 4v53:DI, 4v54:BI, 4v54:DI, 4v55:BI, 4v55:DI, 4v56:BI, 4v56:DI, 4v57:BI, 4v57:DI, 4v5b:AI, 4v5b:CI, 4v5h:BI, 4v5y:BI, 4v5y:DI, 4v64:BI, 4v64:DI, 4v65:B5, 4v66:B5, 4v69:BI, 4v6c:BI, 4v6c:DI, 4v6d:BI, 4v6d:DI, 4v6e:BI, 4v6e:DI, 4v6k:AJ, 4v6l:BJ, 4v6m:BI, 4v6n:AK, 4v6o:BK, 4v6p:BK, 4v6q:BK, 4v6r:BK, 4v6s:AK, 4v6t:BI, 4v6v:BK, 4v6y:BI, 4v6z:BI, 4v70:BI, 4v71:BI, 4v72:BI, 4v73:BI, 4v74:BI, 4v75:BI, 4v76:BI, 4v77:BI, 4v78:BI, 4v79:BI, 4v7a:BI, 4v7b:BI, 4v7c:BK, 4v7d:AK, 4v7i:AI, 4v7s:BI, 4v7s:DI, 4v7t:BI, 4v7t:DI, 4v7u:BI, 4v7u:DI, 4v7v:BI, 4v7v:DI, 4v85:BI, 4v89:BI, 4v9c:BI, 4v9c:DI, 4v9d:CI, 4v9d:DI, 4v9o:AI, 4v9o:CI, 4v9o:EI, 4v9o:GI, 4v9p:AI, 4v9p:CI, 4v9p:EI, 4v9p:GI, 8vs9:L11, 8vsa:L11, 8w51:J, 5wdt:I, 6wd0:i, 6wd1:i, 6wd2:i, 6wd3:i, 6wd4:i, 6wd5:i, 6wd6:i, 6wd7:i, 6wd8:i, 6wd9:i, 6wda:i, 6wdb:i, 6wdc:i, 6wdd:i, 6wde:i, 6wdf:i, 6wdg:i, 6wdh:i, 6wdi:i, 6wdj:i, 6wdk:i, 6wdl:i, 6wdm:i, 5we4:I, 5we6:I, 4wf1:BI, 4wf1:DI, 5wf0:I, 5wfk:I, 5wfs:I, 6wnt:i, 6wnv:i, 6wnw:i, 4woi:BI, 4woi:CI, 4www:RI, 4www:YI, 6xz7:I, 6xza:I2, 6xzb:I2, 4ybb:CJ, 4ybb:DJ, 7yla:Q, 6ysr:I, 6yss:I, 6yst:I, 6ysu:I, 6ztj:BJ
10 6spb:I 140 139 0.5586 0.5786 0.5827 3.06e-52 6spd:I, 6spf:I, 6spg:I, 7unr:J, 7unu:J, 7unv:J, 7unw:J
11 8fmw:AK 139 137 0.5103 0.5324 0.5401 4.63e-45 8fn2:K
12 6xyw:Ai 138 137 0.4276 0.4493 0.4526 5.31e-34
13 7ood:h 128 133 0.4069 0.4609 0.4436 2.41e-32 7p6z:h, 7pah:h, 7pai:h, 7paj:h, 7pak:h, 7pal:h, 7pam:h, 7pan:h, 7pao:h, 7paq:h, 7par:h, 7pas:h, 7pat:h, 7pau:h, 7ph9:h, 7pha:h, 7phb:h, 7phc:h, 7pi8:h, 7pi9:h, 7pia:h, 7pib:h, 7pic:h, 7pio:h, 7pip:h, 7piq:h, 7pir:h, 7pis:h, 7pit:h
14 6ywe:g 147 143 0.4345 0.4286 0.4406 2.03e-31 6yws:g, 6ywv:g, 6ywx:g, 6ywy:g
15 6gaw:BK 176 131 0.3862 0.3182 0.4275 1.96e-29 7a5f:J3, 7a5g:J3, 7a5h:J, 7a5i:J3, 7a5j:J, 7a5k:J3, 5aj4:BK, 8any:J, 6gb2:BK, 6i9r:J, 3j7y:J, 3j9m:J, 8k2a:LK, 8k2b:LK, 7l08:J, 7l20:J, 7nqh:BK, 7nql:BK, 7nsh:BK, 7nsi:BK, 7nsj:BK, 6nu2:J, 6nu3:J, 7o9k:J, 7o9m:J, 7odr:J, 7ods:J, 7odt:J, 7of0:J, 7of2:J, 7of3:J, 7of4:J, 7of5:J, 7of6:J, 7of7:J, 7og4:XJ, 7oi6:J, 7oi7:J, 7oi8:J, 7oi9:J, 7oia:J, 7oib:J, 7oic:J, 7oid:J, 7oie:J, 8oin:BQ, 8oiq:BQ, 8oir:BQ, 8oit:BQ, 5ool:J, 5oom:J, 7pd3:J, 8pk0:J, 7po4:J, 7qi4:J, 7qi5:J, 7qi6:J, 8qsj:J, 8qu1:J, 8qu5:J, 4v19:K, 6vlz:J, 6vmi:J, 8xt0:LK, 8xt1:LK, 8xt2:LK, 8xt3:LK, 6ydp:BK, 6ydw:BK, 6zm5:J, 6zm6:J, 6zs9:XJ, 6zsa:XJ, 6zsb:XJ, 6zsc:XJ, 6zsd:XJ, 6zse:XJ, 6zsg:XJ
16 4v4n:AH 134 130 0.3793 0.4104 0.4231 2.13e-27 4v6u:BH
17 5d8h:C 158 135 0.3655 0.3354 0.3926 2.15e-26 5dar:C, 5dar:F
18 6z1p:An 158 140 0.3655 0.3354 0.3786 5.68e-23
19 4v9f:I 145 135 0.3310 0.3310 0.3556 2.13e-22 3cc2:I, 3cc4:I, 3cc7:I, 3cce:I, 3ccj:I, 3ccl:I, 3ccm:I, 3ccq:I, 3ccr:I, 3ccs:I, 3ccu:I, 3ccv:I, 3cd6:I, 3cma:I, 3cme:I, 3g4s:I, 3g6e:I, 3g71:I, 3i55:I, 3i56:I, 2otj:I, 2otl:I, 2qa4:I, 2qex:I, 1s72:I, 1vq4:I, 1vq5:I, 1vq6:I, 1vq7:I, 1vq8:I, 1vq9:I, 1vqk:I, 1vql:I, 1vqm:I, 1vqn:I, 1vqo:I, 1vqp:I, 1yhq:I, 1yi2:I, 1yij:I, 1yit:I, 1yj9:I, 1yjn:I, 1yjw:I
20 7aih:E 326 152 0.3172 0.1411 0.3026 1.58e-14 7am2:E, 7ane:E
21 6hiv:AK 323 148 0.3241 0.1455 0.3176 2.26e-12 6hix:AK
22 8idt:y 165 140 0.2483 0.2182 0.2571 0.031 7a01:M2, 5a8l:G, 5aj0:Aq, 9bdn:AL12, 9bdp:AL12, 8bhf:f1, 8bpo:r2, 8btk:Bt, 6d90:t, 6d9j:t, 9f1b:Bt, 9f1c:Bt, 9f1d:Bt, 8fkr:BA, 8fks:BA, 8fkt:BA, 8fku:BA, 8fkv:BA, 8fkw:BA, 8fkx:BA, 8fky:BA, 8fkz:BA, 8fl0:BA, 8fl2:BA, 8fl3:BA, 8fl4:BA, 8fl6:BA, 8fl7:BA, 8fl9:BA, 8fla:BA, 8flb:BA, 8flc:BA, 6frk:4, 6ftg:t, 6fti:t, 6ftj:t, 8g5z:LK, 8g60:LK, 8g6j:LK, 6gz3:Aq, 6gz4:Aq, 6gz5:Aq, 6hcf:t3, 6hcj:u3, 6hcm:t3, 6hcq:u3, 8idy:y, 8ine:y, 8inf:y, 8ink:y, 8ipd:y, 8ipx:y, 8ipy:y, 8ir1:y, 8ir3:y, 3j7p:K, 3j92:t, 3jag:t, 3jah:t, 3jai:t, 3jaj:K, 3jan:K, 8k2c:Lt, 7ls1:k, 7ls2:k, 5lzs:t, 5lzt:t, 5lzu:t, 5lzv:t, 5lzw:t, 5lzx:t, 5lzy:t, 5lzz:t, 6mtd:t, 6mte:t, 7nwg:u3, 7nwh:t, 7nwi:t, 7o7y:Bt, 7o7z:Bt, 7o80:Bt, 7o81:Bt, 6olg:Aq, 8p2k:Bt, 8q87:Bt, 6r5q:t, 6r6g:t, 6r6p:t, 6r7q:t, 8scb:t, 6sgc:t2, 6t59:t3, 4v5z:Bi, 4v6x:CK, 8xsx:LK, 8xsy:Lt, 8xsz:Lt, 8yoo:Lt, 8yop:Lt, 6zm7:Lt, 6zme:Lt, 6zmi:Lt, 6zmo:Lt, 6zvk:M2
23 8pv1:LK 158 140 0.2345 0.2152 0.2429 0.12 8i9t:LK, 8i9v:LK, 8i9w:LK, 8i9x:LK, 8i9y:LK, 8i9z:LK, 8ia0:LK, 7olc:LK, 7old:LK, 8oo0:LK, 8pv2:LK, 8pv3:LK, 8pv4:LK, 8pv5:LK, 8pv6:LK, 8pv7:LK, 8pv8:LK, 8pvk:LK, 8pvl:LK, 7z3n:LK, 7z3o:LK
24 4v6w:CK 158 144 0.2414 0.2215 0.2431 0.18
25 4v8m:BM 138 143 0.2621 0.2754 0.2657 0.76
26 5dou:D 1430 37 0.0828 0.0084 0.3243 2.6 5dou:A, 5dou:B, 5dou:C, 6w2j:A
27 6uel:A 1333 37 0.0828 0.0090 0.3243 2.7 6uel:B
28 6w2j:B 1364 37 0.0828 0.0088 0.3243 2.8
29 2fgh:A 721 48 0.1241 0.0250 0.3750 3.1 3a5l:S, 3a5m:S, 3a5n:S, 3a5o:S, 1c0f:S, 1c0g:S, 4cbu:G, 4cbw:G, 4cbx:G, 3ci5:G, 3cip:G, 3cjb:G, 3cjc:G, 1d4x:G, 1dej:S, 1eqy:S, 1esv:S, 2ff3:A, 2ff6:G, 3ffk:A, 3ffk:D, 2fgh:B, 2fh1:A, 2fh1:B, 2fh1:C, 2fh2:A, 2fh2:B, 2fh2:C, 2fh3:A, 2fh3:B, 2fh3:C, 1h1v:G, 6i4d:G, 6i4e:G, 6i4f:G, 6i4g:G, 6i4g:H, 6i4h:G, 6i4i:G, 6i4j:G, 6i4k:G, 6i4l:G, 6i4m:G, 6lje:A, 6lje:B, 6ljf:A, 6ljf:B, 1mdu:A, 1mdu:D, 5mvv:G, 1nlv:G, 1nm1:G, 1nmd:G, 1nph:A, 1p8x:A, 1p8x:B, 1p8x:C, 1p8z:G, 4pkh:E, 4pkh:J, 1rgi:G, 3tu5:B, 5ubo:S, 1yag:G, 1yvn:G, 5zz0:G, 5zz0:A
30 3ml1:B 109 61 0.1103 0.1468 0.2623 3.4 3o5a:B
31 7yse:D 643 40 0.0966 0.0218 0.3500 5.3 7yse:C
32 8cf5:Ee 160 42 0.0897 0.0813 0.3095 5.4 8aaf:z, 8agt:z, 8agu:z, 8agv:z, 8agw:z, 8agx:z, 8agz:z, 8ccs:Ee, 8cdl:Ee, 8cdr:Ee, 8ceh:Ee, 8cg8:Ee, 8cgn:Ee, 8civ:Ee, 8cku:Ee, 8cmj:Ee, 5dge:m2, 5dgf:m2, 6gq1:P2, 6gqb:P2, 6gqv:P2, 8hfr:KM, 3j16:H, 3j77:62, 3j78:62, 5jcs:K, 5juo:P, 5jup:P, 5jus:P, 5jut:P, 5juu:P, 8k2d:LK, 8k82:LK, 6oig:s, 7osa:uL11, 7osm:uL11, 6r84:P, 6r86:P, 6r87:P, 7rr5:P2, 5tgm:m2, 7ug6:q, 7uoo:8, 7uqb:8, 7uqz:8, 7v08:8, 4v4b:BK, 4v6i:BJ, 4v7h:BK, 4v7r:DL, 6xiq:P2, 8y0u:P2, 6ylg:q, 6ylh:q, 7z34:a
33 5an9:D 166 135 0.2552 0.2229 0.2741 7.6 5anb:D, 5anc:D, 6qkl:D
34 6m0q:A 504 71 0.1379 0.0397 0.2817 8.3 4fas:A, 4fas:C, 4fas:B, 1fgj:A, 1fgj:B, 6m0p:A, 6m0p:C, 6m0p:E, 6m0q:C, 6m0q:E, 6m0q:G, 6m0q:I, 6m0q:K, 4n4n:A, 4n4n:C, 4n4n:E, 4n4o:A, 4n4o:C, 4n4o:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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