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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KVSVLDLKGNQLEEIELPLFFSYPVRKDLIRRVFLSEFTKSLQPKGRDPLAGKRTSALSFGINLGIARVPRVKGSGEAAL
APNTVGGRLAFPPTTEKRLVEEVNLKEKKLGIISALAATADPNFVKARGHRFTSNNVPIILVDDFENISKAKEIMDILKS
IGVVDDIKRVKESKGVRAGKGKMRGRRYQIAKGPLIVVSNHKSPVVESASNIPGVNVVSANLVSVIHLAPGGHPGRLTIY
TKSSINILRQR

The query sequence (length=251) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8hku:AL4P 251 251 1.0000 1.0000 1.0000 0.0 8hkv:AL4P, 8hky:AL4P, 8hkz:AL4P, 8hl1:AL4P, 8hl2:AL4P, 8hl3:AL4P, 8hl4:AL4P, 8hl5:AL4P
2 6skf:BE 255 253 0.5020 0.4941 0.4980 7.86e-80 6skg:BE, 6th6:BE
3 4v4n:AD 255 252 0.5020 0.4941 0.5000 1.41e-77 4v6u:BD
4 3cc2:C 246 251 0.4143 0.4228 0.4143 1.27e-52 3cc4:C, 3cc7:C, 3cce:C, 3ccj:C, 3ccl:C, 3ccm:C, 3ccq:C, 3ccr:C, 3ccs:C, 3ccu:C, 3ccv:C, 3cd6:C, 3cma:C, 3cme:C, 3cpw:C, 3cxc:C, 1ffk:C, 3g4s:C, 3g6e:C, 3g71:C, 3i55:C, 3i56:C, 1jj2:C, 1k73:E, 1k8a:E, 1k9m:E, 1kc8:E, 1kd1:E, 1kqs:C, 1m1k:E, 1m90:E, 1n8r:E, 1nji:E, 2otj:C, 2otl:C, 3ow2:C, 1q7y:E, 1q81:E, 1q82:E, 1q86:E, 2qa4:C, 2qex:C, 1qvf:C, 1qvg:C, 1s72:C, 4v9f:C, 1vq4:C, 1vq5:C, 1vq6:C, 1vq7:C, 1vq8:C, 1vq9:C, 1vqk:C, 1vql:C, 1vqm:C, 1vqn:C, 1vqo:C, 1vqp:C, 1w2b:C, 1yhq:C, 1yi2:C, 1yij:C, 1yit:C, 1yj9:C, 1yjn:C, 1yjw:C
5 8ova:Br 367 240 0.3546 0.2425 0.3708 8.23e-52 8ove:Br, 4v8m:Br
6 6rm3:LC0 329 258 0.3745 0.2857 0.3643 3.29e-51
7 3j79:F 390 245 0.3745 0.2410 0.3837 3.45e-51 3jbn:AF, 3jbo:AF, 3jbp:AF, 8tpu:AF, 5umd:F
8 4v3p:LD 372 251 0.3705 0.2500 0.3705 1.22e-49 4v7e:CC
9 8ev3:C 362 254 0.3865 0.2680 0.3819 1.24e-49 8esq:C, 8esr:C, 8etc:C, 8etg:C, 8eug:C, 8eui:C
10 8jiv:CC 376 251 0.3705 0.2473 0.3705 1.63e-49
11 7oya:C1 348 254 0.3825 0.2759 0.3780 1.19e-48 7oyb:C1
12 4v8p:BC 409 247 0.3745 0.2298 0.3806 3.09e-47 4v8p:CC, 4v8p:EC, 4v8p:GC
13 8c3a:l 361 255 0.3865 0.2687 0.3804 8.00e-47 8c3a:AY, 8cq7:l, 8cq7:AY, 8cqw:l, 8cqw:AY, 8cre:l, 8cre:AY, 8oeq:l, 8oeq:AY, 7pzy:l, 7q08:l, 7q0f:l, 7q0p:l, 7q0r:l, 8q5i:l
14 8a98:C 366 238 0.3386 0.2322 0.3571 1.29e-46 8a3w:C, 6az3:C, 3jcs:C, 8ovj:C, 8rxh:LC, 8rxx:LC, 5t2a:p, 5t5h:r
15 6uz7:AC 360 257 0.3944 0.2750 0.3852 1.91e-46 5it7:CC
16 7qep:L4 329 240 0.3825 0.2918 0.4000 4.13e-45
17 6zu5:LC0 325 256 0.3825 0.2954 0.3750 4.50e-45
18 8btd:LC 315 249 0.3904 0.3111 0.3936 6.93e-45 8br8:LC, 8brm:LC, 8bsi:LC, 8bsj:LC, 8btr:LC, 8fru:C, 7pwg:C, 7pwo:C2
19 8p5d:LC0 327 256 0.3586 0.2752 0.3516 1.44e-43 8p60:LC0, 8p60:KC0, 7qca:LC0
20 8azw:s 398 240 0.3506 0.2211 0.3667 2.84e-42 8b2l:s3, 7qiw:F, 7qiz:F
21 5xxb:C 394 237 0.3586 0.2284 0.3797 3.97e-41
22 9bh5:CC 335 254 0.3506 0.2627 0.3465 1.33e-40 9cai:CC
23 7f5s:LC 368 254 0.3745 0.2554 0.3701 2.71e-40 7a01:t2, 8a3d:F, 5aj0:AC, 8b5l:C, 8b6c:C, 9bdl:AL04, 9bdn:AL04, 9bdp:AL04, 7bhp:LC, 8bhf:l3, 8bpo:C2, 8btk:BC, 7cpu:LC, 7cpv:LC, 4d5y:C, 4d67:C, 6d90:C, 6d9j:C, 9f1b:BC, 9f1c:BC, 9f1d:BC, 8fkt:SA, 8fku:SA, 8fkv:SA, 8fkw:SA, 8fkx:SA, 8fky:SA, 8fkz:SA, 8fl2:SA, 8fl3:SA, 8fl4:SA, 8fl6:SA, 8fl7:SA, 8fl9:SA, 8fla:SA, 8flb:SA, 8flc:SA, 8fld:SA, 8fle:SA, 8flf:SA, 9fpz:LC, 9fq0:LC, 6frk:C, 6ftg:C, 6fti:C, 6ftj:C, 8g5y:LC, 8g5z:LC, 8g60:LC, 8g61:LC, 8g6j:LC, 8glp:LC, 6gz3:AC, 6gz4:AC, 6gz5:AC, 6hcf:C3, 6hcj:C3, 6hcm:C3, 6hcq:C3, 8idt:D, 8idy:D, 8ie3:D, 8ifd:1F, 8ife:1F, 8ine:D, 8inf:D, 8ink:D, 6ip5:1F, 6ip6:1F, 6ip8:1F, 8ipd:D, 8ipx:D, 8ipy:D, 8ir1:D, 8ir3:D, 3j7o:C, 3j7p:C, 3j7q:C, 3j7r:C, 3j92:C, 3jag:C, 3jah:C, 3jai:C, 3jaj:C, 3jan:C, 8jdj:I, 8jdk:I, 8jdl:I, 8jdm:I, 8k2c:LC, 5lks:LC, 6lqm:D, 6lsr:D, 6lss:D, 7ls1:F2, 7ls2:F2, 6lu8:D, 5lzs:C, 5lzt:C, 5lzu:C, 5lzv:C, 5lzw:C, 5lzx:C, 5lzy:C, 5lzz:C, 7mdz:C, 6mtb:C, 6mtc:C, 6mtd:C, 6mte:C, 7nfx:C, 7nwg:C3, 7nwh:C, 7nwi:C, 7o7y:BC, 7o7z:BC, 7o80:BC, 7o81:BC, 7obr:C, 8ohd:LC, 8oj0:LC, 8oj5:LC, 8oj8:LC, 6ole:C, 6olf:C, 6olg:AC, 6oli:C, 6olz:AC, 6om0:C, 6om7:C, 7ow7:F, 7oyd:C, 8p2k:BC, 6p5i:AC, 6p5j:AC, 6p5k:AC, 6p5n:AC, 8q7z:BC, 8q87:BC, 8qfd:C, 7qgg:C, 8qoi:LC, 7qvp:MC, 7qvp:LC, 7qwq:C, 7qwr:C, 7qws:C, 6qzp:LC, 6r5q:C, 6r6g:C, 6r6p:C, 6r7q:C, 8rjb:C, 8rjc:C, 8rjd:C, 8scb:C, 6sgc:C2, 6swa:C, 5t2c:F, 6t59:C3, 7tm3:C, 7toq:AL04, 7tor:AL04, 7tut:C, 7ucj:C, 7uck:C, 4ug0:LC, 4ujc:BC, 4ujd:AC, 4uje:CC, 4v5z:Bc, 4v6x:CC, 6w6l:C, 6xa1:LC, 7xnx:LC, 7xny:LC, 8xsx:LC, 8xsy:LC, 8xsz:LC, 6y0g:LC, 8y0w:LC, 8y0x:LC, 6y2l:LC, 6y57:LC, 6y6x:LC, 8yoo:LC, 8yop:LC, 6z6l:LC, 6z6m:LC, 6z6n:LC, 7zjw:LF, 7zjx:LF, 6zm7:LC, 6zme:LC, 6zmi:LC, 6zmo:LC, 6zvk:t2
24 7oyc:C1 351 254 0.3665 0.2621 0.3622 3.14e-40
25 8ip8:EB 399 258 0.3825 0.2406 0.3721 2.30e-39 8ipa:EB, 8ipb:EB
26 4v6w:CC 392 239 0.3108 0.1990 0.3264 3.14e-38 6xu6:CC, 6xu7:CC, 6xu8:CC
27 5xy3:C 362 240 0.3586 0.2486 0.3750 9.30e-38
28 4v6i:BD 329 257 0.3745 0.2857 0.3658 1.97e-36
29 8aaf:l 361 257 0.3745 0.2604 0.3658 3.34e-36 8agt:l, 8agu:l, 8agv:l, 8agw:l, 8agx:l, 8agz:l, 5apn:C, 5apo:C, 7azy:p, 7b7d:LF, 8bip:LC, 8bjq:LC, 8bn3:L4, 8bqd:BE, 8bqx:BE, 8ccs:GG, 8cdl:GG, 8cdr:GG, 8ceh:GG, 8cf5:GG, 8cg8:GG, 8cgn:GG, 8civ:GG, 8cku:GG, 8cmj:GG, 5dat:L4, 5dat:l4, 5dc3:L4, 5dc3:l4, 5dge:L4, 5dge:l4, 5dgf:L4, 5dgf:l4, 5dgv:L4, 5dgv:l4, 6elz:C, 6em1:C, 6em3:C, 6em4:C, 6em5:C, 8eub:AC, 8evp:AC, 8evq:AC, 8evr:AC, 8evs:AC, 8evt:AC, 8ewb:AC, 8ewc:AC, 5fci:L4, 5fci:l4, 5fcj:L4, 5fcj:l4, 6ft6:C, 5gak:G, 6gq1:C, 6gqb:C, 6gqv:C, 5h4p:C, 6hd7:G, 8hfr:DO, 6hhq:l, 6hhq:CF, 5i4l:L4, 5i4l:l4, 6i7o:BE, 6i7o:YE, 3j6x:L4, 3j6y:L4, 3j77:L4, 3j78:L4, 3jct:C, 5jcs:C, 5juo:H, 5jup:H, 5jus:H, 5jut:H, 5juu:H, 8k2d:LC, 8k82:LC, 5lyb:L4, 5lyb:l4, 5m1j:C5, 6m62:C, 5mc6:BE, 5mei:l, 5mei:CF, 7mpi:AC, 7mpj:AC, 6n8j:C, 6n8k:C, 6n8l:C, 6n8m:F, 6n8n:F, 6n8o:F, 7n8b:AC, 7nac:C, 5ndg:L4, 5ndg:l4, 5ndv:L4, 5ndv:l4, 5ndw:L4, 5ndw:l4, 7nrc:LF, 7nrd:LF, 5obm:L4, 5obm:l4, 7of1:C, 7oh3:C, 7ohq:C, 7ohr:C, 7ohs:C, 7ohu:C, 7ohv:C, 7ohw:C, 7ohx:C, 7ohy:C, 6oig:C, 5on6:l, 5on6:CF, 7osa:uL4, 7osm:uL4, 8p8m:LH, 8p8n:LH, 8p8u:LH, 8pfr:LH, 6q8y:BE, 6qik:D, 6qt0:D, 6qtz:D, 7r7a:C, 6r84:G, 6r86:G, 6r87:G, 6ri5:D, 7rr5:LC, 6rzz:D, 6s05:D, 6s47:AF, 6snt:j, 6sv4:BE, 6sv4:YE, 6sv4:ZE, 6t4q:LC, 5t62:F, 5t6r:F, 6t7i:LC, 6t7t:LC, 6t83:Cy, 6t83:Fa, 5tbw:l, 5tbw:CF, 6tb3:BE, 5tga:L4, 5tga:l4, 5tgm:L4, 5tgm:l4, 6tnu:BE, 7too:AL04, 7top:AL04, 7u0h:C, 4u3m:L4, 4u3m:l4, 4u3n:L4, 4u3n:l4, 4u3u:L4, 4u3u:l4, 4u4n:L4, 4u4n:l4, 4u4o:L4, 4u4o:l4, 4u4q:L4, 4u4q:l4, 4u4r:L4, 4u4r:l4, 4u4u:L4, 4u4u:l4, 4u4y:L4, 4u4y:l4, 4u4z:L4, 4u4z:l4, 4u50:L4, 4u50:l4, 4u51:L4, 4u51:l4, 4u52:L4, 4u52:l4, 4u53:L4, 4u53:l4, 4u55:L4, 4u55:l4, 4u56:L4, 4u56:l4, 4u6f:L4, 4u6f:l4, 7ug6:C, 7uoo:C, 7uqb:C, 7uqz:C, 7v08:C, 4v4b:BD, 4v7f:D, 4v7h:BD, 4v7r:BD, 4v7r:DD, 4v88:BC, 4v88:DC, 4v8t:C, 4v8y:BC, 4v8z:BC, 8v83:C, 8v84:C, 8v87:C, 4v91:C, 6woo:C, 6xiq:C, 6xir:C, 8y0u:LC, 6ylg:C, 6ylh:C, 6ylx:C, 6yly:C, 5z3g:G, 7z34:C, 6z6j:LC, 6z6k:LC, 7zpq:BC, 7zrs:BC, 7zs5:BE, 7zuw:BC, 7zux:EC, 7zw0:LG
30 8euy:C 329 237 0.3147 0.2401 0.3333 1.84e-35 8eth:C, 8eti:C, 8etj:C, 8eup:C
31 6zj3:LR 365 240 0.3347 0.2301 0.3500 1.83e-34
32 7olc:LC 363 260 0.3665 0.2534 0.3538 4.82e-31 8i9p:LC, 8i9r:LC, 8i9t:LC, 8i9v:LC, 8i9w:LC, 8i9x:LC, 8i9y:LC, 8i9z:LC, 8ia0:LC, 7old:LC, 8oo0:LC, 8pv1:LC, 8pv2:LC, 8pv3:LC, 8pv4:LC, 8pv5:LC, 8pv6:LC, 8pv7:LC, 8pv8:LC, 8pvk:LC, 8pvl:LC, 7z3n:LC, 7z3o:LC
33 7r81:F1 360 258 0.3466 0.2417 0.3372 7.01e-31
34 7btb:C 336 252 0.3466 0.2589 0.3452 7.53e-31 7bt6:C, 6c0f:C, 6cb1:C, 7ohp:C
35 8fkp:SA 331 249 0.3307 0.2508 0.3333 1.40e-27 8fkq:SA, 8fkr:SA, 8fks:SA
36 4v4p:AF 189 238 0.3068 0.4074 0.3235 1.63e-27 4v4r:BF, 4v4s:BF, 4v4t:BF
37 8e5t:C 283 128 0.1952 0.1731 0.3828 1.37e-20
38 8e5t:C 283 37 0.0558 0.0495 0.3784 6.6
39 7oht:C 239 148 0.2151 0.2259 0.3649 1.00e-15
40 8fl0:SA 274 151 0.1952 0.1788 0.3245 6.79e-14
41 8buu:E 206 162 0.1793 0.2184 0.2778 0.007 7aqc:E, 7aqd:E, 7as8:G, 7as9:G, 6ha1:E, 6ha8:E, 6htq:E, 3j3v:E, 3j3w:E, 3j9w:BF, 5njt:Y, 7o5b:b, 7ope:G, 6ppf:E, 6ppk:E, 6pvk:E, 8qcq:E, 7qgu:E, 7qh4:E, 8qpp:b, 7qv1:E, 7qv2:E, 7qv3:E, 8r55:b, 8s1p:E, 8s1u:E, 7s9u:E, 7sae:E, 6tnn:Y, 6tpq:Y
42 7aih:N 189 65 0.0837 0.1111 0.3231 2.3 7am2:N, 7ane:N
43 7asm:E 206 170 0.1753 0.2136 0.2588 2.9 7asn:E, 7aso:J, 7asp:E, 6ddd:S, 6ddg:S, 6fxc:AE, 6fxc:BE, 5hkv:C, 5hl7:C, 6hma:E, 5li0:F, 5nd8:F, 5nd9:F, 5ngm:AE, 7nhl:I, 7nhm:I, 5nrg:C, 8p2f:I, 8p2g:I, 8p2h:I, 7p48:E, 6s0x:E, 6s0z:E, 6s12:E, 6s13:E, 6sj6:F, 5t7v:LJ, 5tcu:LJ, 7ttu:S, 7ttw:S, 4wce:C, 4wf9:C, 4wfa:C, 4wfb:C, 6wqn:S, 6wqq:S, 6wrs:S, 6wru:S, 8y36:E, 8y37:E, 8y38:E, 8y39:E, 6yef:F
44 2vn0:A 464 46 0.0558 0.0302 0.3043 3.2 2nnh:A, 2nnh:B, 2nni:A, 2nnj:A, 1pq2:A, 1pq2:B
45 8jjr:E 184 86 0.0876 0.1196 0.2558 4.6
46 3bvo:A 197 73 0.0837 0.1066 0.2877 6.6 3bvo:B
47 8hvr:H 158 53 0.0598 0.0949 0.2830 7.5 8jke:H
48 5e58:C 465 42 0.0478 0.0258 0.2857 7.8 5e0e:A, 5e58:D, 5e58:A, 5e58:B, 5e58:E, 5e58:F
49 8uu6:E 205 35 0.0558 0.0683 0.4000 9.6 8a57:I, 8a5i:I, 8a63:I, 7nhn:I, 8uu4:E, 8uu5:E, 8uu7:E, 8uu8:E, 8uu9:E, 8uua:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218