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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KVRWPDFNQEAYVGGTMDPYARNKFNQVESDKLRMDRAIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSV
LKKSPPHLIKEIILVDDYSNDPEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLE
RVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFE
ELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKQHPNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQ
SRLELRKKLSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKH
MDLCLTVVDRAPGSLIKLQGCREDDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQQWKFTLN

The query sequence (length=476) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4d0t:A 496 494 1.0000 0.9597 0.9636 0.0 5ajn:A, 5ajo:A, 5ajp:A, 4d0t:C, 4d0t:F, 4d0t:B, 4d0t:D, 4d0t:E, 4d0z:B, 4d0z:E, 4d0z:A, 4d0z:C, 4d0z:D, 4d0z:F, 4d11:D, 4d11:E, 4d11:B, 4d11:A, 4d11:F, 6e7i:A, 6egs:A, 6egs:B, 2ffu:A, 2ffv:A, 2ffv:B, 5fv9:A, 5fv9:B, 5fv9:C, 5fv9:D, 5fv9:E, 5fv9:F, 5ndf:A, 5ndf:B, 5ndf:C, 5ndf:D, 5ndf:E, 5ndf:F, 6nqt:A, 6nqt:B, 6nqt:C, 6nqt:D, 6nqt:E, 6nqt:F
2 4d11:C 436 448 0.8866 0.9679 0.9420 0.0
3 8v9q:A 500 474 0.4580 0.4360 0.4599 3.01e-146 1xhb:A
4 6e4q:A 505 497 0.4496 0.4238 0.4306 8.21e-132 6e4q:B, 6e4q:C, 6e4q:D
5 6pxu:B 532 478 0.4454 0.3985 0.4435 1.96e-126 6pxu:A
6 6h0b:B 521 468 0.4223 0.3858 0.4295 1.42e-120
7 8v9q:B 449 457 0.4307 0.4566 0.4486 1.97e-114
8 6s24:A 537 493 0.4160 0.3687 0.4016 2.04e-109 6s22:A
9 2d7i:A 536 494 0.3950 0.3507 0.3806 3.66e-107 2d7r:A
10 6iwq:A 546 458 0.3466 0.3022 0.3603 5.38e-100 6iwq:B, 6iwq:C, 6iwq:D, 6iwq:E, 6iwq:F, 6iwr:A, 6iwr:B, 6iwr:C, 6iwr:D, 6iwr:E, 6iwr:F
11 8ujg:A 530 396 0.3256 0.2925 0.3914 9.91e-82 8uhz:A, 8ui1:A, 8ui6:A, 8uje:A, 8ujf:A, 8ujf:B, 8ujg:B, 8ujh:A
12 8r8a:A 127 111 0.0651 0.2441 0.2793 2.97e-06
13 1knm:A 129 117 0.0735 0.2713 0.2991 1.73e-05 1mc9:A
14 1knm:A 129 76 0.0588 0.2171 0.3684 0.001 1mc9:A
15 2aai:B 262 117 0.0693 0.1260 0.2821 1.52e-04 7kd0:B, 3rti:B, 3rtj:B
16 2aai:B 262 83 0.0462 0.0840 0.2651 0.057 7kd0:B, 3rti:B, 3rtj:B
17 1abr:B 267 87 0.0504 0.0899 0.2759 5.08e-04
18 1abr:B 267 58 0.0420 0.0749 0.3448 0.024
19 1rzo:B 262 117 0.0714 0.1298 0.2906 0.001 1rzo:D
20 1rzo:B 262 81 0.0462 0.0840 0.2716 0.026 1rzo:D
21 6h4f:B 318 123 0.0777 0.1164 0.3008 0.001 6h1j:B, 6h21:A, 6h21:B, 6h21:C, 6h2n:A, 6h2n:B, 6h2n:C, 6h4f:C, 6h4f:F, 6h4f:O, 6h4f:P, 6h4f:E, 6h4f:G, 6h4f:Q, 6h4f:A, 6h4f:D, 6h4f:H, 6h4f:I, 6h4m:B, 6h4m:C, 6h4m:F, 6h4m:O, 6h4m:P, 6h4m:E, 6h4m:G, 6h4m:Q, 6h4m:A, 6h4m:D, 6h4m:H, 6h4m:I, 6hnq:B, 6hnq:C, 6hnq:F, 6hnq:O, 6hnq:P, 6hnq:E, 6hnq:G, 6hnq:Q, 6hnq:A, 6hnq:D, 6hnq:H, 6hnq:I
22 3a22:A 614 103 0.0630 0.0489 0.2913 0.007 3a22:B, 3a23:A, 3a23:B
23 1vcl:A 432 117 0.0588 0.0648 0.2393 0.092 1vcl:B, 3w9t:A, 3w9t:C, 3w9t:G, 3w9t:B, 3w9t:F, 3w9t:E, 3w9t:D, 2z48:A, 2z48:B, 2z49:A, 2z49:B
24 1onk:B 263 70 0.0420 0.0760 0.2857 0.17 3d7w:B, 1oql:B, 1pum:B, 1puu:B, 2r9k:B, 2rg9:B, 1sz6:B, 1tfm:B, 1yf8:B
25 1onk:B 263 86 0.0441 0.0798 0.2442 1.4 3d7w:B, 1oql:B, 1pum:B, 1puu:B, 2r9k:B, 2rg9:B, 1sz6:B, 1tfm:B, 1yf8:B
26 5mlz:A 355 106 0.0609 0.0817 0.2736 0.17 5mm0:A, 5mm1:A
27 4hr6:C 264 114 0.0609 0.1098 0.2544 0.38 5y97:C
28 1hwm:B 264 71 0.0420 0.0758 0.2817 1.2 1hwn:B, 1hwo:B, 1hwp:B
29 4zbv:B 261 116 0.0651 0.1188 0.2672 1.3 4zfw:B, 4zfy:B, 4zgr:B, 4zlb:B
30 4owl:D 137 82 0.0483 0.1679 0.2805 1.5 4owj:A, 4owj:B, 4owj:C, 4owj:D, 4owj:E, 4owj:F, 4owj:G, 4owk:A, 4owk:B, 4owk:C, 4owk:D, 4owk:E, 4owk:F, 4owk:G, 4owl:B, 4owl:C, 4owl:E, 4owl:F, 4owl:A, 4owl:G
31 1i5e:A 208 48 0.0294 0.0673 0.2917 3.4 1i5e:B
32 6p8t:H 326 93 0.0525 0.0767 0.2688 5.2 6p8t:C, 6p8t:D, 6p8t:G
33 1unb:A 288 92 0.0462 0.0764 0.2391 5.7 1e5h:A, 1hjf:A, 2jb8:A, 1rxg:A, 1uo9:A, 1uob:A, 1w2a:X, 1w2n:A, 1w2o:A
34 1o5o:A 210 42 0.0315 0.0714 0.3571 6.1 1o5o:B, 1o5o:C, 1o5o:D
35 1isv:A 436 44 0.0336 0.0367 0.3636 9.1 2d20:A, 2d20:B, 2d22:A, 2d22:B, 2d23:A, 2d23:B, 2d24:A, 2d24:B, 1e0v:A, 1e0x:A, 1e0x:B, 2g3j:A, 5gqd:A, 5gqd:B, 5gqe:A, 5gqe:B, 1isv:B, 1isw:A, 1isw:B, 1isx:A, 1isx:B, 1isy:A, 1isy:B, 1isz:A, 1isz:B, 1it0:A, 1it0:B, 1od8:A, 1v0k:A, 1v0l:A, 1v0m:A, 1v0n:A, 1v6u:A, 1v6u:B, 1v6v:A, 1v6v:B, 1v6w:A, 1v6w:B, 1v6x:A, 1v6x:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218