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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KVGSAGRFGARYGLKIRRRVAAVEAKMRQKHTCPVCGRKAVKRISTGIWQCQKCGATFAGGAYLPVTPAGKAVRRITE

The query sequence (length=78) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4v4n:Ai 78 78 1.0000 1.0000 1.0000 1.58e-51 4v6u:Bi
2 6skf:Bg 84 77 0.8590 0.7976 0.8701 3.22e-45 6skg:Bg, 6th6:Bg
3 4v9f:Z 83 75 0.5641 0.5301 0.5867 2.10e-28 3cc2:Z, 3cc4:Z, 3cc7:Z, 3cce:Z, 3ccj:Z, 3ccl:Z, 3ccm:Z, 3ccq:Z, 3ccr:Z, 3ccs:Z, 3ccu:Z, 3ccv:Z, 3cd6:Z, 3cma:Z, 3cme:Z, 3cpw:Y, 3g4s:Z, 3g6e:Z, 3g71:Z, 3i55:Z, 3i56:Z, 2otj:Z, 2otl:Z, 2qa4:Z, 2qex:Z, 1s72:Z, 1vq4:Z, 1vq5:Z, 1vq6:Z, 1vq7:Z, 1vq8:Z, 1vq9:Z, 1vqk:Z, 1vql:Z, 1vqm:Z, 1vqn:Z, 1vqo:Z, 1vqp:Z, 1yhq:Z, 1yi2:Z, 1yij:Z, 1yit:Z, 1yj9:Z, 1yjn:Z, 1yjw:Z
4 3cxc:Y 73 70 0.5769 0.6164 0.6429 4.94e-25 1jj2:Y, 1k73:1, 1k8a:1, 1k9m:1, 1kc8:1, 1kd1:1, 1kqs:Y, 1m1k:1, 1m90:1, 1n8r:1, 1nji:1, 3ow2:Y, 1q7y:1, 1q81:1, 1q82:1, 1q86:1, 1qvf:Y, 1qvg:Y, 1w2b:Y
5 1ffk:W 73 70 0.5513 0.5890 0.6143 5.10e-23
6 7qep:P3 86 71 0.5000 0.4535 0.5493 1.27e-21
7 5xy3:p 89 74 0.4487 0.3933 0.4730 1.15e-20
8 6zu5:LPP 81 70 0.4359 0.4198 0.4857 1.24e-20
9 6rm3:LPP 83 76 0.4615 0.4337 0.4737 7.52e-20
10 7olc:Lp 91 74 0.4231 0.3626 0.4459 5.58e-19 8ia0:Lp, 7old:Lp, 8oo0:Lp, 8pv1:Lp, 8pv2:Lp, 8pv3:Lp, 8pv4:Lp, 8pv5:Lp, 8pv6:Lp, 8pv7:Lp, 8pv8:Lp, 8pvk:Lp, 8pvl:Lp, 7r81:r1, 7z3n:Lp, 7z3o:Lp
11 8c3a:AQ 91 74 0.4359 0.3736 0.4595 9.95e-19 8c3a:CK, 8cq7:AQ, 8cq7:CK, 8cqw:AQ, 8cqw:CK, 8cre:AQ, 8cre:CK, 8oeq:AQ, 8oeq:CK, 7pzy:AQ, 7q08:AQ, 7q0f:AQ, 7q0p:AQ, 7q0r:AQ, 8q5i:AQ
12 4v6w:Cp 91 74 0.4103 0.3516 0.4324 1.50e-17 6xu6:Cp, 6xu7:Cp, 6xu8:Cp
13 5t2a:m 91 74 0.4231 0.3626 0.4459 1.86e-17 8a3w:o, 8a98:o, 6az3:o, 3jcs:m, 8ova:Bo, 8ove:Bo, 8ovj:o, 8rxh:Lo, 8rxx:Lo, 5t5h:o, 4v8m:Bo
14 8fru:p 93 80 0.4359 0.3656 0.4250 2.69e-17 8br8:Lq, 8brm:Lq, 8bsi:Lq, 8bsj:Lq, 8btd:Lq, 8btr:Lq, 7pwg:p, 7pwo:p2
15 6zj3:L5 90 74 0.4231 0.3667 0.4459 3.42e-17
16 4v6i:Bm 92 74 0.4359 0.3696 0.4595 3.56e-17 8aaf:c, 8agt:c, 8agu:c, 8agv:c, 8agw:c, 8agx:c, 8agz:c, 5apn:p, 5apo:p, 7azy:U, 7b7d:Ll, 8bip:Lp, 8bjq:Lp, 8bn3:Q3, 8bqd:AT, 8bqx:AT, 7bt6:p, 7btb:p, 8ccs:b, 8cdl:b, 8cdr:b, 8ceh:b, 8cf5:b, 8cg8:b, 8cgn:b, 8civ:b, 8cku:b, 8cmj:b, 5dat:Q3, 5dat:q3, 5dc3:Q3, 5dc3:q3, 5dge:Q3, 5dge:q3, 5dgf:Q3, 5dgf:q3, 5dgv:Q3, 5dgv:q3, 8eub:Ap, 8evp:Ap, 8evq:Ap, 8evr:Ap, 8evs:Ap, 8evt:Ap, 8ewb:Ap, 8ewc:Ap, 5fci:Q3, 5fci:q3, 5fcj:Q3, 5fcj:q3, 6ft6:p, 5gak:D, 6gq1:p, 6gqb:p, 6gqv:p, 5h4p:p, 6hd7:D, 8hfr:nY, 6hhq:AQ, 6hhq:DR, 5i4l:Q3, 5i4l:q3, 6i7o:AT, 6i7o:XT, 3j6x:83, 3j6y:83, 3j77:93, 3j78:93, 3jct:p, 5jcs:p, 5juo:UA, 5jup:UA, 5jus:UA, 5jut:UA, 5juu:UA, 8k2d:Lp, 8k82:Lp, 5lyb:Q3, 5lyb:q3, 5m1j:p5, 6m62:p, 5mc6:AT, 5mei:AQ, 5mei:DR, 7mpi:Ap, 7mpj:Ap, 6n8j:p, 6n8k:p, 6n8l:p, 6n8m:R, 6n8n:R, 6n8o:R, 7n8b:Ap, 5ndg:Q3, 5ndg:q3, 5ndv:Q3, 5ndv:q3, 5ndw:Q3, 5ndw:q3, 7nrc:Lr, 7nrd:Lr, 5obm:Q3, 5obm:q3, 7of1:p, 7oh3:p, 7ohq:p, 6oig:p, 5on6:AQ, 5on6:DR, 7osa:eL43, 7osm:eL43, 8p8m:RT, 8p8n:RT, 8p8u:RT, 8pfr:RT, 6q8y:AT, 6qik:m, 6qt0:m, 6qtz:m, 6r84:D, 6r86:D, 6r87:D, 6ri5:m, 7rr5:Lp, 6rzz:m, 6s05:m, 6s47:Ar, 6snt:aa, 6sv4:AT, 6sv4:XT, 6sv4:zT, 6t4q:Lp, 5t62:R, 5t6r:R, 6t7i:Lp, 6t7t:Lp, 6t83:pb, 6t83:aa, 5tbw:AQ, 5tbw:DR, 6tb3:AT, 5tga:Q3, 5tga:q3, 5tgm:Q3, 5tgm:q3, 6tnu:AT, 7too:AL43, 7top:AL43, 7u0h:p, 4u3m:Q3, 4u3m:q3, 4u3n:Q3, 4u3n:q3, 4u3u:Q3, 4u3u:q3, 4u4n:Q3, 4u4n:q3, 4u4o:Q3, 4u4o:q3, 4u4q:Q3, 4u4q:q3, 4u4r:Q3, 4u4r:q3, 4u4u:Q3, 4u4u:q3, 4u4y:Q3, 4u4y:q3, 4u4z:Q3, 4u4z:q3, 4u50:Q3, 4u50:q3, 4u51:Q3, 4u51:q3, 4u52:Q3, 4u52:q3, 4u53:Q3, 4u53:q3, 4u55:Q3, 4u55:q3, 4u56:Q3, 4u56:q3, 4u6f:Q3, 4u6f:q3, 7ug6:p, 7uoo:p, 7uqb:p, 7uqz:p, 7v08:p, 4v4b:B9, 4v7f:k, 4v7h:B9, 4v7r:Bg, 4v7r:Dg, 4v88:Bp, 4v88:Dp, 4v8t:p, 4v91:p, 6woo:p, 6xiq:p, 6xir:p, 8y0u:Lp, 6ylg:p, 6ylh:p, 6yly:p, 7z34:p, 6z6j:Lp, 6z6k:Lp, 7zpq:Bo, 7zrs:Bo, 7zs5:BB, 7zuw:Bo, 7zux:Eo, 7zw0:Ls
17 5it7:pp 87 74 0.4103 0.3678 0.4324 3.77e-17 6uz7:Bp
18 5xxb:o 90 74 0.3974 0.3444 0.4189 4.90e-17
19 9bh5:Cp 88 74 0.4103 0.3636 0.4324 5.43e-17 9cai:Cp
20 4v3p:Lm 92 74 0.3974 0.3370 0.4189 6.21e-16 8azw:a, 8b2l:a3, 8ip8:GB, 8ipa:GB, 8ipb:GB, 8jiv:Cp, 7qiw:q, 7qiz:q, 4v7e:Cp, 1ysh:D
21 7a01:I2 91 82 0.4231 0.3626 0.4024 6.98e-16 8a3d:j, 5aj0:Ap, 8b5l:p, 8b6c:p, 9bdl:AL43, 9bdn:AL43, 9bdp:AL43, 7bhp:Lp, 8bhf:c1, 8bpo:o2, 8btk:Bp, 7cpu:Lp, 7cpv:Lp, 4d5y:p, 4d67:p, 6d90:p, 6d9j:p, 9f1b:Bp, 9f1c:Bp, 9f1d:Bp, 7f5s:Lp, 8fkz:LX, 8fl2:LX, 8fl3:LX, 8fl4:LX, 8fl6:LX, 8fl7:LX, 8fl9:LX, 8fla:LX, 8flb:LX, 8flc:LX, 8fld:LX, 8fle:LX, 8flf:LX, 6frk:p, 6ftg:p, 6fti:p, 6ftj:p, 8g5y:Lp, 8g5z:Lp, 8g60:Lp, 8g61:Lp, 8g6j:Lp, 8glp:Lp, 6gz3:Ap, 6gz4:Ap, 6gz5:Ap, 6hcf:p3, 6hcj:p3, 6hcm:p3, 6hcq:p3, 8idt:X, 8idy:X, 8ie3:X, 8ifd:2j, 8ife:2j, 8ine:X, 8inf:X, 8ink:X, 6ip5:2j, 6ip6:2j, 6ip8:2j, 8ipd:X, 8ipx:X, 8ipy:X, 8ir1:X, 8ir3:X, 3j7o:p, 3j7p:p, 3j7q:p, 3j7r:p, 3j92:p, 3jag:p, 3jah:p, 3jai:p, 3jaj:p, 3jan:p, 8jdj:u, 8jdk:u, 8jdl:u, 8jdm:u, 8k2c:Lp, 5lks:Lp, 6lqm:X, 6lsr:X, 6lss:X, 7ls1:j2, 7ls2:j2, 6lu8:X, 5lzs:p, 5lzt:p, 5lzu:p, 5lzv:p, 5lzw:p, 5lzx:p, 5lzy:p, 5lzz:p, 7mdz:p, 6mtb:p, 6mtc:p, 6mtd:p, 6mte:p, 7nfx:p, 7nwg:p3, 7nwh:p, 7nwi:p, 7o7y:Bp, 7o7z:Bp, 7o80:Bp, 7o81:Bp, 7obr:p, 8ohd:Lp, 8oj0:Lp, 8oj5:Lp, 8oj8:Lp, 6ole:q, 6olf:q, 6olg:Ap, 6oli:q, 6olz:Ap, 6om0:q, 6om7:q, 7ow7:j, 7oya:p1, 7oyb:p1, 7oyc:p1, 7oyd:p, 8p2k:Bp, 6p5i:Ap, 6p5j:Ap, 6p5k:Ap, 6p5n:Ap, 8q7z:Bp, 8q87:Bp, 8qfd:p, 7qgg:q, 8qoi:Lp, 7qvp:Lp, 7qvp:Mp, 7qwq:p, 7qwr:p, 7qws:p, 6qzp:Lp, 6r5q:p, 6r6g:p, 6r6p:p, 6r7q:p, 8rjb:p, 8rjc:p, 8rjd:p, 8scb:p, 6sgc:p2, 6swa:n, 5t2c:j, 6t59:p3, 7tm3:p, 7toq:AL43, 7tor:AL43, 7tut:p, 7ucj:p, 7uck:p, 4ug0:Lp, 4ujc:Bp, 4ujd:Ap, 4uje:Cp, 4v5z:Bz, 4v6x:Cp, 6w6l:q, 6xa1:Lp, 7xnx:Lp, 7xny:Lp, 8xsx:Lp, 8xsy:Lp, 8xsz:Lp, 6y0g:Lp, 8y0w:Lp, 8y0x:Lp, 6y2l:Lp, 6y57:Lp, 6y6x:Lp, 8yoo:Lp, 8yop:Lp, 6z6l:Lp, 6z6m:Lp, 6z6n:Lp, 7zjw:Lr, 7zjx:Lr, 6zm7:Lp, 6zme:Lp, 6zmi:Lp, 6zmo:Lp, 6zvk:I2
22 8p5d:LPP 87 67 0.3590 0.3218 0.4179 2.53e-15 8p60:LPP, 8p60:KPP, 7qca:LPP
23 4v8p:BY 102 68 0.3846 0.2941 0.4412 1.20e-14 4v8p:CY, 4v8p:EY, 4v8p:GY
24 8eug:K 90 63 0.3590 0.3111 0.4444 5.87e-13 8eui:K
25 8hku:L37A 65 65 0.3846 0.4615 0.4615 6.68e-13 8hkv:L37A, 8hky:L37A, 8hkz:L37A, 8hl1:L37A, 8hl2:L37A, 8hl3:L37A, 8hl4:L37A, 8hl5:L37A
26 3j79:h 85 74 0.3846 0.3529 0.4054 2.70e-12 3jbn:Ah, 3jbo:Ah, 3jbp:Ah, 8tpu:Ah, 5umd:h
27 6knb:B 1120 30 0.1795 0.0125 0.4667 0.013 6knc:B
28 7qep:D6 101 50 0.2436 0.1881 0.3800 0.51
29 8d4a:A 1207 23 0.1282 0.0083 0.4348 0.77 8d4b:A
30 1l1o:C 173 35 0.1282 0.0578 0.2857 1.1 1l1o:F
31 5iy6:B 1165 26 0.1154 0.0077 0.3462 1.1 8a40:B, 7b0y:B, 8b3d:B, 8b3f:B, 8bvw:B, 8byq:B, 8bz1:B, 7edx:p, 7eg7:p, 7eg8:p, 7eg9:p, 7ega:p, 7egb:p, 7egc:p, 7ena:PB, 7enc:PB, 6exv:B, 5flm:B, 8gxq:PB, 8gxs:PB, 5iy7:B, 5iy8:B, 5iy9:B, 5iya:B, 5iyb:B, 5iyc:B, 5iyd:B, 7lbm:B, 7nvr:B, 7nvs:B, 7nvt:B, 7nvu:B, 7nvy:B, 7nvz:B, 7nw0:B, 8oeu:B, 8oev:B, 8oew:B, 8of0:B, 5oik:B, 7okx:B, 7oky:B, 7ol0:B, 7oo3:B, 7oob:B, 7oop:B, 7opc:B, 7opd:B, 8p4f:B, 8s52:B, 8s54:B, 8s55:B, 8uha:B, 8uhd:B, 8uhg:B, 8ui0:B, 8uis:B, 8w8e:B, 8w8f:B, 8wak:p, 8wal:p, 8wan:p, 8wao:p, 8wap:p, 8waq:p, 8war:p, 8was:p, 8wat:p, 8wau:p, 8wav:p, 8waw:p, 8wax:p, 8way:p, 8waz:p, 8wb0:p, 7zwd:B, 7zx7:B, 7zx8:B
32 6gmh:B 1132 26 0.1154 0.0080 0.3462 1.2 8a3y:B, 6gml:B, 8p4a:B, 8p4b:B, 8p4c:B, 8p4d:B, 8p4e:B, 7pks:B, 8rbx:B, 8s51:B, 8s5n:B, 6ted:B, 7unc:B, 7und:B, 7ycx:2
33 2d74:B 137 27 0.1538 0.0876 0.4444 1.2 2dcu:B
34 4c2x:A 388 44 0.1923 0.0387 0.3409 1.9 6pau:A
35 7ysf:A 113 44 0.1667 0.1150 0.2955 2.1
36 5npq:A 355 49 0.2179 0.0479 0.3469 2.2
37 7owu:B 395 49 0.2179 0.0430 0.3469 2.2 4c2y:A, 4c2y:B, 4c2z:A, 4c2z:B, 6ehj:A, 6ehj:B, 6f56:A, 6f56:B, 6f56:C, 6f56:D, 6fz2:A, 6fz2:B, 6fz3:A, 6fz3:B, 6fz5:A, 6fz5:B, 3iu1:A, 3iu1:B, 3iu2:A, 3iu2:B, 3iwe:A, 3iwe:B, 3jtk:A, 3jtk:B, 5mu6:A, 5mu6:B, 5npq:B, 5o6h:A, 5o6h:B, 5o6j:A, 5o6j:B, 5o9s:A, 5o9s:B, 5o9t:A, 5o9t:B, 5o9u:A, 5o9u:B, 5o9v:A, 5o9v:B, 7owm:A, 7owm:B, 7own:A, 7own:B, 7owo:A, 7owo:B, 7owp:B, 7owp:A, 7owq:A, 7owq:B, 7owr:B, 7owr:A, 7owu:A, 6pav:B, 6pav:A, 8q23:B, 8q23:A, 8q24:B, 8q24:A, 8q26:A, 8q26:B, 8q2z:A, 8q2z:B, 8q3d:A, 8q3d:B, 8q3s:A, 8q3s:B, 8q3t:A, 8q3t:B, 6qrm:A, 6qrm:B, 7rk3:A, 1rxt:C, 6sjz:B, 6sjz:A, 6sk2:A, 6sk2:B, 6sk3:A, 6sk3:B, 6sk8:A, 6sk8:B, 6skj:A, 6skj:B, 5uut:A, 5uut:B
38 8he5:M 64 62 0.1538 0.1875 0.1935 2.5 6ir9:M, 6j4w:M, 6j4x:M, 6j4y:M, 6j51:M, 8jh2:M, 7wbv:M, 7wbx:M, 7xn7:M, 5xog:M, 7xse:M, 7xsx:M, 7xsz:M, 7xt7:M, 7xtd:M, 7xti:M
39 1mm3:A 61 54 0.1923 0.2459 0.2778 2.7
40 8h1j:A 362 42 0.1795 0.0387 0.3333 3.2 8ex9:A, 8exa:A
41 8oki:B 1101 24 0.1538 0.0109 0.5000 3.3 8cro:B, 8orq:B, 8p2i:B, 8rbo:B
42 3qqc:A 381 24 0.1538 0.0315 0.5000 3.4
43 6gys:B 579 17 0.1026 0.0138 0.4706 3.9 6f07:B, 6gyp:B, 6gys:C, 6gys:J, 6gys:I, 6gyu:B, 7k7g:M, 8ow1:CE
44 6mg0:B 1687 16 0.1282 0.0059 0.6250 4.4
45 6mfz:A 1789 16 0.1282 0.0056 0.6250 4.4 5es7:A, 5es8:A, 5es8:B, 5es9:A, 6mfw:A, 6mfx:A, 6mfy:A, 6mg0:A, 6ulz:A
46 7ymi:C 420 22 0.1538 0.0286 0.5455 4.6 7ymi:c, 7ymm:1C, 7ymm:2C, 7ymm:3C, 7ymm:4C
47 3kta:B 171 19 0.1282 0.0585 0.5263 5.1
48 4qiw:B 1069 24 0.1667 0.0122 0.5417 5.4 4qiw:J
49 6kf3:B 1114 24 0.1667 0.0117 0.5417 6.0 9bct:B, 9bcu:B, 6kf4:B, 6kf9:B
50 8jkz:A 584 21 0.1026 0.0137 0.3810 6.1 8in8:B, 8jl0:A, 8k87:B, 8k87:G, 8k88:B
51 2han:A 78 45 0.1667 0.1667 0.2889 6.2 1r0o:A, 4umm:A
52 1v9p:A 584 27 0.1282 0.0171 0.3704 6.7 1dgs:A, 1dgs:B, 1v9p:B
53 6kc0:A 674 51 0.2051 0.0237 0.3137 9.4 6kbd:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218