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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KVELVFVPGPGIGHLSTALQIADLLLRRDHRLSVTVLSIPLPSRIRFISLPQRQAVFETQKQNVKEAVAKLSDSSILAGL
VLDMFCVTMVDVAKQLGVPSYVFFTSSAGYLSFTSHLQDLSDRHGKETQQLMRSDVEIAVPGFTNPVPGKVIPGVYFNKN
MAEWLHDCARRFRETNGILVNTFSELESQVMDSFSDATAASQFPAVYAVGPILSLNAASSESQSGDEILKWLDQQPPSSV
VFLCFGSKGSLNPDQAREIAHALERSGHRFVWSLRQPSPKGKFEKPIEYDNIEDVLPEGFLDRTAEMGRVIGWAPQVEIL
GHPATGGFVSHCGWNSTLESLWYGVPIATWPMYAEQHFNAFEMGVELGLAVGISSESSIEEGVIVSAEKIEEGIRKLMGG
GGGEVRKLVKAKSEESRKSVMEGGSSFTSLNRFIDEVMK

The query sequence (length=439) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7bv3:B 439 439 1.0000 1.0000 1.0000 0.0
2 7bv3:A 457 462 0.9886 0.9497 0.9394 0.0
3 8wp5:A 479 480 0.5011 0.4593 0.4583 3.00e-139
4 8w53:B 479 480 0.4920 0.4509 0.4500 7.23e-139 8w53:A
5 8hoj:A 451 469 0.4875 0.4745 0.4563 9.83e-129 8hoj:B
6 2acv:A 461 474 0.4396 0.4187 0.4072 3.96e-109 2acv:B, 2acw:A, 2acw:B
7 8ita:A 429 455 0.3895 0.3986 0.3758 6.24e-83 8inp:A
8 7q3s:A 453 471 0.3462 0.3355 0.3227 3.47e-69
9 6jem:A 440 455 0.3531 0.3523 0.3407 5.71e-68 6jem:B, 6jem:C, 6jen:A, 6jen:B, 6jen:C
10 6su6:A 467 470 0.3895 0.3662 0.3638 2.10e-67 5nlm:A, 6su6:B, 6su7:A
11 2vg8:A 465 464 0.3508 0.3312 0.3319 4.37e-67 2vce:A, 2vch:A
12 5nlm:B 448 466 0.3804 0.3728 0.3584 6.30e-65
13 8chd:A 461 465 0.3417 0.3254 0.3226 6.50e-64 8chd:B
14 6jtd:A 477 387 0.2870 0.2642 0.3256 2.04e-61 6jtd:B
15 8j2t:A 477 480 0.3098 0.2851 0.2833 4.42e-57 8j2s:A, 8j2s:B, 8j2s:C, 8j2s:D, 8j2s:E, 8j2s:F, 8j2s:G, 8j2t:B, 8j2u:A, 8j2u:B, 8j2v:A, 9j9c:A, 9j9c:B, 9j9c:C, 9j9c:D, 9j9c:E, 9j9c:F, 9j9c:G, 9j9k:A, 9j9k:B
16 7va8:A 456 363 0.2916 0.2807 0.3526 1.47e-52 7va8:B, 7vaa:A, 7vaa:B
17 6llz:A 436 461 0.3030 0.3050 0.2885 3.52e-50 7cyw:A, 6llw:A, 6llw:B, 6llz:B
18 6l5s:A 454 468 0.3257 0.3150 0.3056 3.71e-50 6l5p:A, 6l5q:A, 6l5r:A, 6l7h:A
19 6lzy:A 454 492 0.3257 0.3150 0.2907 8.94e-48 6lzx:A, 6lzx:B, 6lzy:B, 7vej:A, 7vej:B, 7vek:A, 7vek:B, 7vel:A, 7vel:B
20 6lfz:B 439 451 0.3098 0.3098 0.3016 4.44e-47 6lfz:A
21 6lg0:B 444 475 0.3189 0.3153 0.2947 6.42e-47 6lg0:A, 6lg0:C, 6lg0:D, 6lg0:E, 6lg0:F
22 6lg1:A 429 394 0.2711 0.2774 0.3020 2.98e-45 6lg1:B
23 7c2x:A 490 383 0.2916 0.2612 0.3342 1.10e-44
24 8hjo:B 440 248 0.2210 0.2205 0.3911 8.50e-42 8hjf:A, 8hjf:B, 8hjg:A, 8hjg:B, 8hjh:A, 8hjh:B, 8hjk:A, 8hjl:A, 8hjl:B, 8hjn:A, 8hjn:B, 8hjo:A, 8hjp:A, 8hjp:B, 8j66:A
25 8w7y:A 474 371 0.2369 0.2194 0.2803 1.47e-40
26 8i0d:A 446 365 0.2346 0.2309 0.2822 3.17e-40 8i0e:A
27 8inh:B 454 359 0.2187 0.2115 0.2674 1.89e-39 8inh:A
28 8cgq:A 458 473 0.2802 0.2686 0.2600 3.66e-39 6lf6:A
29 8i90:A 440 410 0.2528 0.2523 0.2707 5.00e-39 8i90:B, 8i94:A, 8i94:B
30 3hbj:A 445 395 0.2756 0.2719 0.3063 9.57e-39 3hbf:A
31 2c1z:A 439 424 0.2620 0.2620 0.2712 5.80e-38 2c1x:A, 2c9z:A
32 5u6n:B 448 379 0.2574 0.2522 0.2982 6.72e-37 5u6m:A, 5u6m:B, 5u6n:A, 5u6s:A, 5u6s:B, 5v2j:A, 5v2j:B, 5v2k:A, 5v2k:B
33 8wrk:A 434 290 0.2096 0.2120 0.3172 8.38e-37 8in7:A, 8ina:A, 8ind:A, 8inj:A, 8ino:A, 8inv:A, 8wrj:A
34 7zer:A 474 457 0.2847 0.2637 0.2735 6.84e-36 7zf0:A
35 6inh:A 450 471 0.2938 0.2867 0.2739 7.20e-35 6inf:A, 6ing:A, 6ini:A, 6kvi:A, 6kvj:A, 6kvk:A, 6kvl:A, 6o86:A, 6o87:A, 6o88:A
36 7w0k:A 457 467 0.2711 0.2604 0.2548 2.96e-34 7w0z:A, 7w10:A, 7w1b:A, 7w1h:A
37 7w11:A 435 463 0.2688 0.2713 0.2549 1.46e-33
38 8wvd:A 450 363 0.2255 0.2200 0.2727 4.32e-32 6l8z:A
39 5tmb:A 451 269 0.1777 0.1729 0.2900 1.23e-29 6bk0:A, 6bk1:A, 6bk2:A, 6bk3:A, 5tmd:A, 5tme:A
40 4rel:A 446 303 0.1800 0.1771 0.2607 2.31e-28 4rem:A, 4ren:A, 4whm:A
41 7es1:A 408 136 0.1276 0.1373 0.4118 4.66e-27 7erx:A, 7es0:A, 7es2:A
42 6ija:A 415 277 0.1913 0.2024 0.3032 7.48e-25 6ij9:A, 6ij9:B, 6ij9:C, 6ija:B, 6ijd:A, 6ijd:B
43 6ij9:D 388 274 0.1663 0.1881 0.2664 1.71e-19
44 2iya:A 392 90 0.0752 0.0842 0.3667 1.58e-06 2iya:B
45 7vlb:A 385 103 0.0774 0.0883 0.3301 5.90e-06
46 7vlb:B 353 103 0.0774 0.0963 0.3301 7.72e-06
47 6kqx:A 327 103 0.0820 0.1101 0.3495 8.62e-06
48 7lvy:A 431 131 0.0774 0.0789 0.2595 8.96e-05 7mco:A, 7mco:B
49 7vm0:B 406 161 0.1048 0.1133 0.2857 1.89e-04 8h5d:A, 8h5d:B, 7vm0:A
50 8sft:B 428 186 0.1093 0.1121 0.2581 8.16e-04 8gkn:A, 8gkn:B, 8sft:A, 8sft:C, 8sft:D, 8sfu:A, 8sfu:B, 8sfw:A, 8sfy:A
51 7xx4:A 395 66 0.0524 0.0582 0.3485 0.003 2iyf:A, 2iyf:B, 4m83:A, 4m83:B, 7xx4:B
52 6j31:B 387 107 0.0706 0.0801 0.2897 0.078 6j31:A, 6j31:C, 6j31:D
53 3ia7:A 397 173 0.0911 0.1008 0.2312 0.92 3ia7:B
54 4tv5:A 245 74 0.0501 0.0898 0.2973 3.7 4tv6:A
55 7c4c:A 332 78 0.0683 0.0904 0.3846 4.1 7c42:A, 7c43:A, 7c45:A, 7c47:A, 7c4b:A
56 6ldv:L 214 42 0.0319 0.0654 0.3333 4.1 6ldx:L
57 9g13:E 127 27 0.0296 0.1024 0.4815 5.3 9g13:A, 9g13:C, 9g13:G
58 2oek:A 412 48 0.0364 0.0388 0.3333 5.7 2oej:B, 2oek:B, 2oel:A, 2oel:B, 2oem:A, 2oem:B
59 2iv7:A 370 103 0.0524 0.0622 0.2233 6.7 2iw1:A
60 5uba:A 261 68 0.0410 0.0690 0.2647 7.6
61 2ycb:B 635 25 0.0251 0.0173 0.4400 8.6 2ycb:A
62 7jwp:B 216 38 0.0273 0.0556 0.3158 8.7 7jwp:D, 7jwp:F, 7jwp:H, 7jwp:J, 7jwp:L, 7jwp:N, 7jwp:P, 7jwq:B, 7jwq:D
63 3oth:A 395 43 0.0364 0.0405 0.3721 9.1 3otg:A, 3oth:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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