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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KTYQSRDLVLEPIQHPKSIELGMPEVDQSVLAEVAERENVIIGVRPVDEKSKSLIASKMYSSKGLFVKAKSSDWGPMSGF
IPVDQSFAKASARRDLEKFNEYAEQSILSGNAVSANLYLNQVRIEELVSKYESLTPLELDVDSGMYKTTATNGDQTIPFF
LNKVTVDDKELWQVHYLREGELAPFKVIGDPVSKQPMTADYDLLTVMYTYGDLGPQDKVKQPLTWEQWKESVTYEDLSPK
YKARYDNQALYEKQDGASLGMVSDRLKELKDVINTSLGRTDGLEMVHHGADDANPYAVMADNFPATFFVPKHFFDDDGLG
EGKGSIQTYFNVNEQGAVVIQNPQEFSNFQQVAINASYRASLNDKWNSGLDSPLFTTKRKLSHDYLDARDEVAKKLG

The query sequence (length=397) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8bo1:B 398 397 1.0000 0.9975 1.0000 0.0 8bo1:D, 8br0:B, 8br0:D, 8br1:B, 8br1:D
2 7p1g:M 347 300 0.2217 0.2536 0.2933 5.15e-30 7p1g:K, 7p1g:L, 7p1g:N, 7p1g:O
3 1sk6:A 481 289 0.2065 0.1705 0.2837 5.98e-14 1k90:B, 1pk0:B, 1s26:B
4 1sk6:B 454 291 0.2065 0.1806 0.2818 9.01e-14
5 1xfu:A 735 289 0.2065 0.1116 0.2837 1.29e-13 1k90:A, 1k90:C, 1lvc:A, 1lvc:C, 1pk0:A, 1pk0:C, 1s26:A, 1s26:C, 1sk6:C, 1xfu:B, 1xfu:C, 1xfu:D, 1xfu:E, 1xfu:F, 1xfv:A, 1xfv:B, 1xfv:C, 1xfv:D, 1xfv:E, 1xfv:F, 1xfw:A, 1xfw:B, 1xfw:C, 1xfw:D, 1xfw:E, 1xfw:F, 1xfx:A, 1xfx:B, 1xfx:C, 1xfx:D, 1xfx:E, 1xfx:F, 1xfy:A, 1xfy:B, 1xfy:C, 1xfy:D, 1xfy:E, 1xfy:F, 1xfz:A, 1xfz:B, 1xfz:C, 1xfz:D, 1xfz:E, 1xfz:F, 1y0v:A, 1y0v:B, 1y0v:C, 1y0v:D, 1y0v:E, 1y0v:F
6 1zot:A 351 303 0.1889 0.2137 0.2475 1.09e-12 2col:A
7 8jxc:A 1337 87 0.0579 0.0172 0.2644 0.96 2i1p:A, 8jxb:B, 8jxh:B, 8jxi:A
8 8em4:A 3818 87 0.0579 0.0060 0.2644 1.3 8em4:B
9 8em7:A 4378 87 0.0579 0.0053 0.2644 1.3 8em7:B, 8jut:A, 8jut:B, 8juu:B, 8juu:A, 8jx8:B, 8jx8:A, 8jx9:B, 8jxa:A, 8jxb:A, 8jxd:A, 8jxe:A, 8jxe:B, 8jxf:B, 8jxg:A, 8jxh:A, 8jxi:B
10 6b58:C 544 80 0.0579 0.0423 0.2875 3.6 6b58:A
11 5umh:B 310 69 0.0605 0.0774 0.3478 4.1 5umh:A
12 7ceb:A 553 81 0.0453 0.0325 0.2222 4.2 7cec:A
13 5vpn:E 585 80 0.0579 0.0393 0.2875 4.2 6awf:A, 2b76:A, 2b76:M, 1kf6:A, 1kf6:M, 1kfy:A, 1kfy:M, 4kx6:A, 4kx6:M, 1l0v:A, 1l0v:M, 3p4p:A, 3p4p:M, 3p4q:A, 3p4q:M, 3p4r:A, 3p4r:M, 3p4s:A, 3p4s:M, 5vpn:A
14 7a0r:C 197 53 0.0504 0.1015 0.3774 4.4 7a0s:C, 7a18:C, 3cf5:C, 3dll:C, 5dm6:C, 5dm7:C, 4io9:C, 4ioa:C, 4ioc:C, 1j5a:K, 5jvg:C, 5jvh:C, 1jzx:K, 1jzy:K, 1jzz:K, 1k01:K, 1nkw:C, 1nwx:C, 1nwy:C, 3pio:C, 3pip:C, 1sm1:C, 4u67:C, 4v49:BC, 4v4a:BC, 4v4g:BF, 4v4g:DF, 4v4g:FF, 4v4g:HF, 4v4g:JF, 4wfn:C, 1xbp:C, 2zjp:C, 2zjq:C, 2zjr:C
15 4jo3:H 227 36 0.0353 0.0617 0.3889 4.9 4jo1:H, 4jo1:I, 4jo3:I
16 6eri:BC 217 49 0.0403 0.0737 0.3265 7.1 5mmj:c, 5mmm:c, 4v61:AC, 5x8p:c, 5x8r:c

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218