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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KTLQQIDKLICSWLKQIDNVIPQLIMEMTTETKRLVTNVDKQIQQQFQQFLATYFPEHQLLAEEKSNAMITNEINHLWIM
DPIDGTANLVKQQEDYCIILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAFCNGFKMEEPPSLKLEDAIISFNAQVMNLD
TVQDLFDASFSYRLVGACGLDSMRVAKGQFGAHINTNPKPWDIAAQFLFAELLNLKMTTLDGKAIDHLKGAPFIISNKAC
HETVLKILNANGGYQKYR

The query sequence (length=258) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5eyg:B 265 262 1.0000 0.9736 0.9847 0.0 5eyg:A, 5eyh:A, 5eyh:B, 5f24:A, 5f24:B, 4g61:A, 4g61:B, 4i3e:A, 4i3e:B, 4i3y:A, 4i3y:B, 4i40:A, 4i40:B, 4ptk:A, 4ptk:B, 3ryd:A, 3ryd:C
2 5dw8:A 260 225 0.2636 0.2615 0.3022 6.06e-30 5dw8:B, 5j16:A, 5j16:B, 5j16:C, 5j16:D
3 2p3n:A 256 243 0.2597 0.2617 0.2757 1.61e-24 2p3n:B, 2p3n:C, 2p3n:D
4 6ib8:B 270 195 0.2054 0.1963 0.2718 5.38e-23 6ib7:A, 6ib8:A, 2qfl:A, 6tqn:T, 6tqn:S, 6tqo:T, 6tqo:S
5 8wdq:A 273 228 0.2287 0.2161 0.2588 5.22e-20 8wdq:B
6 6giu:A 275 243 0.2403 0.2255 0.2551 5.21e-16 4as4:A, 4as4:B, 1awb:A, 1awb:B, 6giu:B, 6gj0:A, 6gj0:B, 2hhm:A, 2hhm:B, 1ima:A, 1ima:B, 1imb:A, 1imb:B, 1imc:A, 1imc:B, 1imd:A, 1imd:B, 1ime:A, 1ime:B, 6zk0:AAA, 6zk0:BBB
7 2czi:A 259 191 0.1977 0.1969 0.2670 8.14e-16 2czh:B
8 2bji:A 274 225 0.2209 0.2080 0.2533 2.34e-14 2bji:B
9 5zon:A 256 225 0.2209 0.2227 0.2533 1.79e-13 5yht:A, 5yht:B, 5zon:B, 5zon:C, 5zon:D
10 3luz:B 234 194 0.2054 0.2265 0.2732 2.46e-13
11 3lv0:A 258 178 0.1822 0.1822 0.2640 4.08e-12 3luz:A, 3lv0:B
12 4as5:A 274 210 0.1938 0.1825 0.2381 8.36e-12 4as5:B, 4as5:C, 4as5:D
13 1dk4:A 252 165 0.1667 0.1706 0.2606 1.66e-09 1dk4:B, 1g0h:A, 1g0h:B, 1g0i:A, 1g0i:B
14 5eq9:B 260 99 0.0969 0.0962 0.2525 8.34e-08 5eq8:A, 5eq9:A, 5eq9:C, 5eq9:D, 5t3j:A
15 6b5z:A 252 195 0.1822 0.1865 0.2410 4.87e-05 6b5z:B, 6b60:A, 6b60:B, 6b61:A, 6b61:B, 6b62:A, 6b62:B, 6b63:A, 6b63:B, 6b64:A, 6b64:B, 6b65:A, 6b65:B, 6b66:A, 6b66:B, 1lbx:A, 1lbx:B, 1lby:A, 1lby:B, 1lbz:A, 1lbz:B
16 4hxv:A 317 274 0.2248 0.1830 0.2117 0.001 4o7i:A
17 5djj:A 257 211 0.1628 0.1634 0.1991 0.005 5djg:A, 5djh:A, 5dji:A, 5djk:A
18 4qxd:B 289 99 0.1008 0.0900 0.2626 0.030 4qxd:A
19 8f9y:A 352 33 0.0504 0.0369 0.3939 0.11
20 4qr8:A 441 73 0.0814 0.0476 0.2877 0.46 4qr8:B
21 1k9y:A 354 73 0.0775 0.0565 0.2740 0.57 1k9z:A, 1ka0:A, 1ka1:A, 1qgx:A
22 3e65:B 421 114 0.0969 0.0594 0.2193 2.7 2bhj:A, 1df1:A, 1df1:B, 1dwv:A, 1dwv:B, 1dww:A, 1dww:B, 1dwx:A, 1dwx:B, 3dwj:A, 3dwj:B, 3e65:A, 3e67:A, 3e67:B, 3e68:A, 3e68:B, 3e6l:A, 3e6l:B, 3e6n:A, 3e6n:B, 3e6o:A, 3e6o:B, 3e6t:A, 3e6t:B, 3e7i:A, 3e7i:B, 3e7m:A, 3e7m:B, 3e7t:A, 3e7t:B, 3eai:A, 3eai:B, 3ebd:A, 3ebd:B, 3ebf:A, 3ebf:B, 4js9:A, 4js9:B, 1jwj:A, 1jwj:B, 1jwk:A, 1jwk:B, 1m8d:A, 1m8d:B, 1m8e:A, 1m8e:B, 1m8h:A, 1m8h:B, 1m8i:A, 1m8i:B, 1m9t:A, 1m9t:B, 1n2n:A, 1n2n:B, 1noc:A, 1nod:A, 1nod:B, 2nod:A, 2nod:B, 3nod:A, 3nod:B, 3nqs:A, 3nqs:B, 3nw2:A, 3nw2:B, 1qom:A, 1qom:B, 1qw4:A, 1qw4:B, 1qw5:A, 1qw5:B, 1r35:A, 1r35:B, 4ux6:B, 1vaf:A, 1vaf:B, 2y37:A, 2y37:B
23 7bvp:A 869 67 0.0736 0.0219 0.2836 3.8 7bvp:B, 7bvp:C, 7bvp:D, 7bvp:E, 7bvp:F, 6scg:A, 6scg:B, 6sci:A, 6sci:B, 6tqh:A, 6tqh:B, 6tqm:B, 6tqm:A
24 5mlt:A 454 50 0.0581 0.0330 0.3000 9.3 5swa:A, 5swa:B, 5swb:A, 5swb:C, 5swb:D, 5swb:G
25 3cx5:P 185 74 0.0814 0.1135 0.2838 9.5 3cx5:E, 3cxh:P, 3cxh:E, 8e7s:C, 8e7s:c, 8ec0:C, 8ec0:c, 1ezv:E, 6giq:E, 6giq:P, 6hu9:E, 6hu9:P, 2ibz:E, 1kb9:E, 1kyo:E, 1kyo:P, 1p84:E, 4pd4:E, 6t0b:E, 6t0b:P, 6t15:E, 6t15:P, 6ymx:E, 6ymx:P

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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