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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDLPDAIHNDGASDVDLMNWAKKGVII
PVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHIYSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIK
VLEAFKNGDPNGNGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVKFIRQLQEKGL
IDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAGPSGQKHVARTNGMGFARDKMVITSVNKNLELT
AKWIDAQYAPLQSVQNNWGTYGDDKQQNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAK
WRLDLIKEYYVPYMSNVNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWDDYKKELEKYGLSDYLAIK
QKYYDQYQA

The query sequence (length=489) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5g5y:A 494 489 1.0000 0.9899 1.0000 0.0 5g5y:B, 5g5z:A, 5g5z:B, 5g5z:C, 5g5z:D, 5g60:A, 5g60:B, 5g60:C, 5g60:D, 5g61:A, 5g61:B, 5g61:C, 5g61:D, 5g62:A, 5g62:B
2 5h71:B 492 470 0.2740 0.2724 0.2851 1.02e-40 5h6u:A, 5h6u:B, 5h71:A, 1j1n:A, 1j1n:B, 6jhx:A, 6jhx:B, 1kwh:A, 4tqu:Q, 4xig:Q, 4xtc:Q
3 3a09:A 490 477 0.2822 0.2816 0.2893 4.83e-40 3vlu:A, 3vlv:A, 3vlw:A, 3vlw:B, 1y3n:A, 1y3p:A, 1y3q:A
4 3omb:A 503 496 0.2883 0.2803 0.2843 3.40e-37
5 5gub:A 474 492 0.2883 0.2975 0.2866 4.09e-37 5gub:B, 5gub:C, 5gx6:A, 5gx6:B, 5gx6:C, 5gx7:A, 5gx7:B, 5gx7:C, 5gx8:A, 5gx8:B, 6inz:A, 5xs8:A, 5xs8:B, 5xs8:C, 5xs8:D
6 4rk9:A 384 327 0.1575 0.2005 0.2355 7.94e-04 4rk9:B
7 4r2b:A 395 118 0.0695 0.0861 0.2881 0.002 4r2b:B
8 7oyc:L1 199 165 0.0777 0.1910 0.2303 0.002
9 6pre:A 386 156 0.0838 0.1062 0.2628 0.009 2i58:A, 2i58:B, 6pql:A, 6pql:B, 6pql:C, 6pql:D, 6pre:B, 6pre:C, 6pre:D, 6prg:A, 6prg:B
10 8wm6:g 219 136 0.0736 0.1644 0.2647 0.10 8wmv:g, 8wmw:g
11 4r2f:A 394 164 0.0900 0.1117 0.2683 0.10
12 7ehq:A 406 160 0.0757 0.0911 0.2313 0.56 7ehu:A
13 7a01:a7 210 165 0.0675 0.1571 0.2000 0.79 8a3d:r, 5aj0:AL, 8b5l:L, 8b6c:L, 9bdl:AL13, 9bdn:AL13, 9bdp:AL13, 7bhp:LL, 8bhf:t3, 8bpo:K2, 8btk:BL, 7cpu:LL, 7cpv:LL, 4d5y:L, 4d67:L, 6d90:L, 6d9j:L, 9f1b:BL, 9f1c:BL, 9f1d:BL, 7f5s:LL, 8fkp:L6, 8fkq:L6, 8fkr:L6, 8fks:L6, 8fkt:L6, 8fku:L6, 8fkv:L6, 8fkw:L6, 8fkx:L6, 8fky:L6, 8fkz:L6, 8fl2:L6, 8fl3:L6, 8fl4:L6, 8fl6:L6, 8fl7:L6, 8fl9:L6, 8fla:L6, 8flb:L6, 8flc:L6, 8fld:L6, 8fle:L6, 8flf:L6, 6frk:L, 6ftg:L, 6fti:L, 6ftj:L, 8g5y:LL, 8g5z:LL, 8g60:LL, 8g61:LL, 8g6j:LL, 8glp:LL, 6gz3:AL, 6gz4:AL, 6gz5:AL, 6hcf:L3, 6hcj:L3, 6hcm:L3, 6hcq:L3, 8idt:Q, 8idy:Q, 8ie3:Q, 8ifd:2F, 8ife:2F, 8ine:Q, 8inf:Q, 8ink:Q, 6ip5:2F, 6ip6:2F, 6ip8:2F, 8ipd:Q, 8ipx:Q, 8ipy:Q, 8ir1:Q, 8ir3:Q, 3j7o:L, 3j7p:L, 3j7q:L, 3j7r:L, 3j92:L, 3jag:L, 3jah:L, 3jai:L, 3jaj:L, 3jan:L, 8jdj:Q, 8jdk:Q, 8jdl:Q, 8jdm:Q, 8k2c:LL, 5lks:LL, 6lqm:Q, 6lsr:Q, 6lss:Q, 7ls1:F1, 7ls2:F1, 6lu8:Q, 5lzs:L, 5lzt:L, 5lzu:L, 5lzv:L, 5lzw:L, 5lzx:L, 5lzy:L, 5lzz:L, 7mdz:L, 6mtb:L, 6mtc:L, 6mtd:L, 6mte:L, 7nfx:L, 7nwg:L3, 7nwh:L, 7nwi:L, 7o7y:BL, 7o7z:BL, 7o80:BL, 7o81:BL, 7obr:L, 8ohd:LL, 8oj0:LL, 8oj5:LL, 8oj8:LL, 6ole:M, 6olf:M, 6olg:AL, 6oli:M, 6olz:AL, 6om0:M, 6om7:M, 7ow7:r, 7oyd:L, 8p2k:BL, 6p5i:AL, 6p5j:AL, 6p5k:AL, 6p5n:AL, 8q7z:BL, 8q87:BL, 8qfd:L, 7qgg:M, 8qoi:LL, 7qvp:ML, 7qvp:LL, 7qwq:L, 7qwr:L, 7qws:L, 6qzp:LL, 6r5q:L, 6r6g:L, 6r6p:L, 6r7q:L, 8rjb:L, 8rjc:L, 8rjd:L, 8scb:L, 6sgc:L2, 6swa:K, 5t2c:r, 6t59:L3, 7tm3:L, 7toq:AL13, 7tor:AL13, 7tut:L, 7ucj:L, 7uck:L, 4ug0:LL, 4ujc:BL, 4ujd:AL, 4uje:CL, 4v6x:CL, 6w6l:M, 6xa1:LL, 7xnx:LL, 7xny:LL, 8xsx:LL, 8xsy:LL, 8xsz:LL, 6y0g:LL, 8y0w:LL, 8y0x:LL, 6y2l:LL, 6y57:LL, 6y6x:LL, 8yoo:LL, 8yop:LL, 6z6l:LL, 6z6m:LL, 6z6n:LL, 7zjw:LO, 7zjx:LO, 6zm7:LL, 6zme:LL, 6zmi:LL, 6zmo:LL, 6zvk:a7
14 5dvi:A 396 114 0.0634 0.0783 0.2719 0.79 5dvi:B, 5dvj:A, 5dvj:B
15 6wce:A 314 117 0.0695 0.1083 0.2906 1.0
16 7y3w:A 440 53 0.0327 0.0364 0.3019 3.0 7y3w:B, 7y3x:A, 7y3x:B, 7y3y:A, 7y3y:B
17 4g68:A 392 72 0.0450 0.0561 0.3056 3.7 4g68:B
18 3hr4:A 189 47 0.0348 0.0899 0.3617 5.6 3hr4:C, 3hr4:E, 3hr4:G
19 5k8e:A 473 77 0.0450 0.0465 0.2857 5.6 5l6f:A, 5l6g:A
20 7nh7:A 295 67 0.0429 0.0712 0.3134 6.4
21 3a01:F 61 33 0.0245 0.1967 0.3636 8.2 3a01:B, 3lnq:A
22 8hui:C 399 86 0.0491 0.0602 0.2791 9.5 8hui:A, 8hui:B
23 6f45:B 72 26 0.0266 0.1806 0.5000 9.6 6f45:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218