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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGAR
PAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLI
VGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNS
LPAYINLLTIVAIAIPVFYFAWMVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPF
FAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLNSQM
MSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL

The query sequence (length=455) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6fmr:A 475 473 1.0000 0.9579 0.9619 0.0 4d2b:A, 4d2d:A, 5d58:A, 5d59:A, 6eia:A, 6fmy:A, 6ghj:A, 5oxl:A, 5oxm:A, 5oxn:A, 5oxo:A, 5oxq:A, 4xnj:A, 6yof:A, 6yog:A
2 5oxp:A 462 461 0.9780 0.9632 0.9653 0.0 7ac6:A, 4d2c:A, 5d6k:A, 5oxk:A, 4xni:A
3 4ikz:A 485 474 0.5121 0.4804 0.4916 4.58e-139
4 6gz9:A 488 478 0.4220 0.3934 0.4017 1.44e-113 6exs:A, 6hzp:A
5 7q0m:A 482 442 0.3538 0.3340 0.3643 5.89e-71
6 6gs4:A 468 427 0.2527 0.2457 0.2693 4.40e-38
7 8b17:A 451 463 0.2747 0.2772 0.2700 6.74e-33 8b18:A, 8b19:A, 8b1a:A, 8b1b:A, 8b1c:A, 8b1d:A, 8b1e:A, 8b1f:A, 8b1g:A, 8b1h:A, 8b1i:A, 8b1j:A, 8b1k:A
8 4tpg:A 459 422 0.2418 0.2397 0.2607 2.16e-32 4lep:A, 4lep:B, 4tph:A, 4tpj:B, 4tpj:A
9 4uvm:A 505 448 0.2571 0.2317 0.2612 6.11e-30
10 9bis:A 472 446 0.2527 0.2436 0.2578 1.99e-25 9bir:A, 9bit:A, 9biu:A
11 6ei3:A 511 462 0.2637 0.2348 0.2597 1.25e-23
12 7pmy:A 657 343 0.2088 0.1446 0.2770 1.13e-21
13 7pmx:A 657 376 0.2154 0.1492 0.2606 2.77e-18 7pmw:A
14 5a2o:A 470 188 0.1011 0.0979 0.2447 2.86e-06
15 8jzs:B 486 360 0.1582 0.1481 0.2000 4.87e-04 8jzs:A, 8jzu:A, 8wx4:B, 8wx4:A
16 8jzx:A 455 194 0.0923 0.0923 0.2165 0.002 8jzx:B
17 8jzx:A 455 94 0.0505 0.0505 0.2447 6.2 8jzx:B
18 8qsk:A 523 374 0.1582 0.1377 0.1925 0.050 8qsk:C, 8qsl:A, 8qsl:C, 8wx5:A
19 6tpk:A 461 38 0.0286 0.0282 0.3421 0.71 7qvm:R
20 7ryc:O 285 38 0.0286 0.0456 0.3421 0.81
21 8ttg:A 374 123 0.0615 0.0749 0.2276 0.93 8tte:A
22 7aaq:A 487 132 0.0791 0.0739 0.2727 1.3 7aar:A, 6h7d:A
23 1vbi:A 340 65 0.0462 0.0618 0.3231 2.6
24 3dwr:B 275 72 0.0462 0.0764 0.2917 4.2
25 8bpx:M 494 129 0.0791 0.0729 0.2791 5.5 7a23:M, 7aqq:M, 7ar7:M, 7ar8:M, 7arb:M, 8bef:M
26 6mpx:A 673 46 0.0374 0.0253 0.3696 7.0 1t61:C, 1t61:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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