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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KSHAAYIDYALRRTTNMPVEMMGSDVVRLKDYQHFVARVFLGLDSMHSLLLFHETGVGKTMTTVYILKHLKDIYTNWAII
LLVKKALIEDPWMNTILRYAPEITKDCIFINYDDQNFRNKFFTNIKTINSKSRICVIIDECHNFISKSLIKEDGKIRPTR
SVYNFLSKTIALKNHKMICLSATPIVNSVQEFTMLVNLLRPGSLQHQSLFENKRLVDEKELVSKLGGLCSYIVNNEFSIF
DDVEGSASFAKKTVLMRYVNMSKKQEEIYQKAKLAEIKTGISSFRILRRMATTFTFNDFKNSLRDREFSKSALDTFKKGE
LLKGDASAADISLFTELKEKSVKFIDVCLGILASHGKCLVFEPFQSGIEILLLYFKVFGISNIEFSSRTKDTRIKAVAEF
NQESNTNGECIKTCVFSSSGGEGISFFSINDIFILDMTWNEASLRQIVGRAIRLNSHVLTPPERRYVNVHFIMARLSNGM
PTVDEDLFEIIQSKSKEFVQLFRVFKHTSLEWIHANEKDFSPIDNESGWKTLVSRAIDLSSKKNITNKLIEGTNIWYSNS
NRLMSINRGFKGVDGRVYDVDGNYLHDMIKIHDGKLIYIF

The query sequence (length=600) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6rfl:Y 600 600 1.0000 1.0000 1.0000 0.0 7aoh:Y, 8c8h:Y
2 8kcc:K 508 435 0.1533 0.1811 0.2115 3.85e-09 8j90:K, 8kcb:K, 8wh5:K, 8wh8:K, 8wh9:K, 8wha:K, 8wha:L
3 9gd1:W 849 463 0.1700 0.1201 0.2203 6.78e-09
4 6ne3:W 461 456 0.1717 0.2234 0.2259 8.60e-09 8v4y:W, 8v6v:W, 8v6v:X, 8v7l:W
5 7tn2:W 895 471 0.1733 0.1162 0.2208 9.10e-09 9gd2:W, 9gd3:W
6 7ux9:P 468 449 0.1533 0.1966 0.2049 1.13e-07
7 6pwf:K 454 452 0.1550 0.2048 0.2058 2.60e-06
8 8atf:G 442 424 0.1383 0.1878 0.1958 3.43e-06 8oo9:G, 8oos:G
9 6ftx:W 878 467 0.1617 0.1105 0.2077 4.87e-06 6g0l:W, 5j70:A, 5j70:B, 3mwy:W, 3ted:A
10 8he5:O 516 436 0.1583 0.1841 0.2179 8.84e-06
11 8x19:I 864 221 0.0767 0.0532 0.2081 3.00e-05 8x1c:I
12 6g0l:M 855 472 0.1550 0.1088 0.1970 5.65e-05 7nkx:W, 5o9g:W
13 7zi4:G 682 271 0.1017 0.0894 0.2251 9.91e-05
14 7zi4:G 682 115 0.0483 0.0425 0.2522 3.1
15 8tvy:M 558 466 0.1650 0.1774 0.2124 1.35e-04 5vvr:M
16 8x15:I 792 204 0.0717 0.0543 0.2108 4.88e-04
17 8oo7:G 704 178 0.0583 0.0497 0.1966 0.001 8oop:G
18 8oo7:G 704 84 0.0350 0.0298 0.2500 6.6 8oop:G
19 6fml:G 731 166 0.0533 0.0438 0.1928 0.001 8av6:G
20 6fml:G 731 84 0.0350 0.0287 0.2500 5.8 8av6:G
21 7x3t:V 792 251 0.0967 0.0732 0.2311 0.004 6iro:L, 6jyl:K, 6k1p:K, 7x3w:K, 2y9z:A
22 7x3t:V 792 104 0.0467 0.0354 0.2692 0.089 6iro:L, 6jyl:K, 6k1p:K, 7x3w:K, 2y9z:A
23 7epu:B 748 480 0.1617 0.1297 0.2021 0.004 8b0a:K, 7enn:K, 7otq:K
24 7y8r:I 732 431 0.1450 0.1189 0.2019 0.021
25 6gej:M 688 248 0.0900 0.0785 0.2177 0.026 6gen:M
26 6gej:M 688 111 0.0417 0.0363 0.2252 4.0 6gen:M
27 7jl0:A 662 141 0.0667 0.0604 0.2837 0.064 7jl2:A, 7jl2:C, 7jl2:E
28 5l4g:K 393 79 0.0383 0.0585 0.2911 0.13 8cvt:D, 5gjq:K, 5gjr:K, 5gjr:y, 5m32:e, 6msb:D, 6msd:D, 6mse:D, 6msg:D, 6msh:D, 6msj:D, 6msk:D, 7qxn:D, 7qxp:D, 7qxu:D, 7qxw:D, 7qxx:D, 7qy7:D, 7qya:D, 7qyb:D, 5t0c:AD, 5t0c:BD, 5t0g:D, 5t0h:D, 5t0i:D, 5t0j:D, 5vfp:D, 5vfq:D, 5vfr:D, 5vfs:D, 7w37:D, 7w38:D, 7w39:D, 7w3a:D, 7w3b:D, 7w3c:D, 7w3f:D, 7w3g:D, 7w3h:D, 7w3i:D, 7w3j:D, 7w3m:D, 6wjd:D, 6wjn:D
29 7vdv:A 809 455 0.1583 0.1174 0.2088 0.19 7vdt:A
30 7z8s:E 1514 478 0.1650 0.0654 0.2071 0.20 7zb5:E, 7zb5:H
31 4gl2:A 617 137 0.0633 0.0616 0.2774 0.22 4gl2:B
32 6fvt:K 394 97 0.0433 0.0660 0.2680 0.46 6ef0:K, 6ef1:K, 6ef2:K, 6ef3:K, 6fvu:K, 6fvv:K, 6fvw:K, 6fvx:K, 6fvy:K, 5mp9:K, 5mpa:K, 5mpb:K, 5mpc:K, 7qo4:K, 7qo5:K, 7qo6:K
33 5jxt:M 324 102 0.0433 0.0802 0.2549 0.47 5jxt:N, 5jxt:O, 5jxt:J, 5jxt:K, 5jxt:I, 5jxt:H
34 6eg2:A 619 211 0.0817 0.0792 0.2322 0.50 6eg3:A
35 6h0b:B 521 68 0.0333 0.0384 0.2941 0.69
36 1z63:A 468 177 0.0600 0.0769 0.2034 0.88 1z63:B
37 6uxw:A 778 114 0.0433 0.0334 0.2281 1.3 7egp:A, 6iy2:O, 6iy3:O, 6uxv:A, 5x0x:O, 5x0y:O, 5z3l:O, 5z3o:O, 5z3u:O, 5z3v:O
38 7zke:E 1623 206 0.0883 0.0327 0.2573 1.5
39 5jc7:A 641 166 0.0783 0.0733 0.2831 1.7
40 9c57:G 878 93 0.0400 0.0273 0.2581 1.8
41 1z3i:X 644 81 0.0367 0.0342 0.2716 1.9
42 7z7n:E 1306 49 0.0317 0.0145 0.3878 2.5
43 4y0u:A 243 64 0.0333 0.0823 0.3125 2.7 7vvi:A, 7vx3:A, 7vx6:A, 4y0u:B, 4y0u:C, 4y0u:D
44 6vz4:K 616 201 0.0733 0.0714 0.2189 2.9 6kw3:Y, 6kw4:Y, 6kw5:Q
45 6lt4:A 623 36 0.0250 0.0241 0.4167 3.2 6lt4:B, 6lt4:C, 6lt4:D, 6lt4:E, 6lt4:F, 6lt4:G, 6lt4:H, 6lt4:I, 6lt4:J, 6lt4:K, 6lt4:L, 6lt4:M, 6lt4:N
46 1tuf:A 434 75 0.0317 0.0438 0.2533 3.4 1tuf:B, 1twi:A, 1twi:B, 1twi:C, 1twi:D
47 4xco:C 157 45 0.0300 0.1146 0.4000 3.9
48 6tda:S 783 201 0.0733 0.0562 0.2189 4.2
49 2sqc:A 623 37 0.0183 0.0177 0.2973 6.2 1gsz:A, 1gsz:B, 1gsz:C, 1h35:A, 1h35:B, 1h35:C, 1h36:A, 1h36:B, 1h36:C, 1h37:A, 1h37:B, 1h37:C, 1h39:A, 1h39:B, 1h39:C, 1h3a:A, 1h3a:B, 1h3a:C, 1h3b:A, 1h3b:B, 1h3b:C, 1h3c:A, 1h3c:B, 1h3c:C, 1o6h:A, 1o6h:B, 1o6h:C, 1o6q:A, 1o6q:B, 1o6q:C, 1o6r:A, 1o6r:B, 1o6r:C, 1o79:A, 1o79:B, 1o79:C, 2sqc:B, 1ump:A, 1ump:B, 1ump:C
50 6h61:A 660 201 0.0867 0.0788 0.2587 6.4 6g1s:A, 6g1x:A, 7nga:A
51 7xyf:K 656 99 0.0400 0.0366 0.2424 6.6 7xyg:K
52 7b9q:A 868 57 0.0267 0.0184 0.2807 9.2 7b9q:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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