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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KRYVVGISGASGIVLAVTLVSELARLGHHIDVIISPSAQKTLYYELDTKSFLSTIPQNFHNQIVLHHISSIIDATIIVPC
SVATVAAISCGLADNLLRRVADVALKEKRPLILVPREAPLSAIHLENLLKLAQNGAVILPPMPIWYFKPQTAEDIANDIV
GKILAILQLDSPLIK

The query sequence (length=175) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7km3:F 190 185 1.0000 0.9211 0.9459 3.31e-122 7km2:L, 7km2:D, 7km2:I, 7km2:A, 7km2:B, 7km2:K, 7km2:C, 7km2:E, 7km2:J, 7km2:F, 7km2:G, 7km2:H, 7km3:L, 7km3:D, 7km3:I, 7km3:A, 7km3:B, 7km3:G, 7km3:K, 7km3:C, 7km3:E, 7km3:H, 7km3:J
2 6m8v:A 183 179 0.4286 0.4098 0.4190 2.54e-42
3 6qlg:A 188 176 0.4000 0.3723 0.3977 4.48e-38 6qlg:C, 6qlg:B, 6qlg:E, 6qlg:D, 6qlg:F
4 6qlh:A 208 186 0.4114 0.3462 0.3871 1.54e-36 6qli:A, 6qlj:A, 6qlk:A, 6qll:A, 6qlv:A, 6qlv:B, 6qlv:C, 6qlv:D, 6qlv:H, 6qlv:E, 6qlv:F, 6qlv:K, 6qlv:G, 6qlv:I, 6qlv:J, 6qlv:L, 4zaf:A, 4zag:A, 4zal:A, 4zan:A, 4zav:A, 4zaw:A, 4zax:A, 4zay:A, 4zaz:A, 3zqu:A
5 6m8t:A 189 174 0.3771 0.3492 0.3793 7.09e-35 6m8u:A
6 1sbz:D 185 182 0.3943 0.3730 0.3791 1.26e-34 1sbz:A, 1sbz:B, 1sbz:C
7 4rhe:B 203 192 0.3543 0.3054 0.3229 1.20e-27 4rhe:A, 4rhe:E, 4rhe:C, 4rhe:D, 4rhe:F
8 6tgv:C 389 149 0.2343 0.1054 0.2752 7.07e-05 8ow5:A, 8ow5:B, 8ow5:C, 8ow5:D, 8owb:A, 8owb:B, 8owb:C, 8owb:D, 8owp:A, 8owp:B, 8owp:C, 8owp:D, 8owq:A, 8owq:B, 8owq:C, 8owq:D, 8owr:A, 8owr:C, 8owr:D, 4qji:A, 4qji:B, 6tgv:A, 6tgv:B, 6tgv:D, 6th2:A, 6th2:C, 6thc:A, 6thc:B, 6thc:C, 6thc:D
9 1e20:A 185 122 0.2057 0.1946 0.2951 0.005 1mvl:A, 1mvn:A
10 3qjg:A 171 87 0.1371 0.1404 0.2759 0.031 3qjg:C, 3qjg:B, 3qjg:D, 3qjg:E, 3qjg:F, 3qjg:G, 3qjg:I, 3qjg:H, 3qjg:J, 3qjg:L, 3qjg:K
11 8a8h:B 146 64 0.0971 0.1164 0.2656 1.2
12 4zcf:C 627 37 0.0686 0.0191 0.3243 1.7
13 5o9z:L 459 48 0.0857 0.0327 0.3125 2.8
14 1g5q:A 174 100 0.1314 0.1322 0.2300 3.4 1g5q:D, 1g5q:G, 1g5q:L, 1g63:A, 1g63:B, 1g63:H, 1g63:C, 1g63:J, 1g63:D, 1g63:F, 1g63:E, 1g63:G, 1g63:I, 1g63:L, 1g63:K
15 8xme:A 1176 37 0.0743 0.0111 0.3514 3.4 7eu0:A, 8xmb:A, 8xmc:A, 8xmd:A
16 3ia7:A 397 30 0.0686 0.0302 0.4000 3.4 3ia7:B
17 1kq3:A 364 129 0.2171 0.1044 0.2946 4.4
18 2am1:A 454 74 0.1143 0.0441 0.2703 4.9 2am2:A, 3zm5:A, 3zm6:A
19 6fqy:A 468 46 0.0743 0.0278 0.2826 5.1 6fqy:B, 6fqz:A, 6fqz:B
20 6eoa:A 193 63 0.1029 0.0933 0.2857 5.4
21 8fac:A 1377 50 0.0857 0.0109 0.3000 6.5 8e04:A
22 6q8j:A 188 48 0.0857 0.0798 0.3125 7.1
23 4a8x:C 125 30 0.0571 0.0800 0.3333 7.2
24 6pwy:B 513 79 0.1200 0.0409 0.2658 8.2 6pwy:A, 6pwy:D, 6pwy:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218