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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KQYPLNVPAPHHFTYAVRDLPEVTVEQRERALQATHYNEFAFPSGMLTVDMLSDSGTTAMTNHQWASLFLGDEAYGRNTG
YYVLLDTFRDIFERGGEKNWKKIIDLVRTDCRDVEKMMDEVYLCEYEGGLFNGGAAQMERPNAFIIQQGRAAESVLMEIV
RNILAKRHPGKKFTIPSNGHFDTTEGNIKQMGSIPRNLYNKTLLWETPEGGRYEKNPFKGNMDIEKLEQLIQGVGPENVP
LIFTCITNNPVCGQAVSMGNLKEINRVAHKYNIPLVFDTARWAENAYFIKMNEEGYADKSIAEIATEMFSYCDAFTMSAK
KDGHANMGGMLAFRDKGLFWKNFSDFNEDGTVKTDVGVLLKVKQISCYGNDSYGGMSGRDIMALAVGLYESCDFNYMNER
VAQCNYLAEGFYDAGVKGVVLPAGGHAVYINMDEFFDGKRGHDTFAGEGFSLELIRRYGIRVSELGDYSMEYDLKTPEQQ
AEVCNVVRFAIDRSRLTKEHLDYVIAAVKALYEDRENIPNMRIVWGHNLPMRHFHAFLEPYANE

The query sequence (length=544) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8sl7:D 544 544 1.0000 1.0000 1.0000 0.0 8sl7:A, 8sl7:B, 8sl7:C
2 8sbg:A 456 526 0.3382 0.4035 0.3498 3.11e-84
3 8sij:A 445 537 0.3346 0.4090 0.3389 3.33e-82 8sij:B
4 2c44:C 468 539 0.3235 0.3761 0.3265 3.84e-79 2c44:A, 2c44:D, 2c44:B, 5d8g:A
5 8v4a:A 466 516 0.3015 0.3519 0.3178 9.00e-77 9bnj:A, 9bnj:B, 9bnj:C, 9bnj:D, 8v2k:A, 8v2k:B, 8v2k:C, 8v2k:D, 8v4a:B, 8v4a:C, 8v4a:D, 8v6p:A, 8v6p:B, 8v6p:C, 8v6p:D, 8v9p:A, 8v9p:B, 8v9p:C, 8v9p:D, 5w19:A, 5w19:B, 5w19:C, 5w19:D
6 1c7g:A 456 525 0.2904 0.3465 0.3010 9.31e-69 1c7g:B, 1c7g:C, 1c7g:D, 6dur:A, 6dur:B, 6dvx:A, 6dvx:B, 6dyt:A, 6dyt:B, 6dz5:A, 6dz5:B, 6ecg:A, 2ez2:A, 2ez2:B, 7fjk:A, 7fjk:B, 7fjk:C, 7fjk:D, 6mls:A, 6mls:B, 6mme:A, 6mme:B, 6mo3:A, 6mo3:B, 6mpd:A, 6mpd:B, 6mqq:A, 6mqq:B, 6nv8:A, 6nv8:B, 7tcs:A, 7tcs:B, 7tcs:C, 7tcs:D, 7tdl:A, 7tdl:B, 7tdl:C, 7tdl:D, 2tpl:B, 2vlf:A, 2vlf:B, 2vlh:A, 2vlh:B, 2ycn:A, 2ycn:B, 2ycp:A, 2ycp:B, 2ycp:C, 2ycp:D, 2yct:A, 2yct:B, 2yhk:A, 2yhk:B
7 4w1y:B 433 534 0.2978 0.3741 0.3034 4.55e-65
8 2zc0:A 405 85 0.0478 0.0642 0.3059 0.63 2zc0:B, 2zc0:C, 2zc0:D
9 4wbt:A 369 42 0.0312 0.0461 0.4048 0.71 4wbt:B, 4wbt:C
10 6cd1:A 452 179 0.0846 0.1018 0.2570 1.3 6ccz:A, 6ccz:B, 6cd1:B, 6cd1:C, 6cd1:D, 6cd1:E, 6cd1:F, 6cd1:G, 6cd1:H
11 7e13:A 475 144 0.0680 0.0779 0.2569 1.9 7e13:B, 7e13:C, 7e13:D
12 8e77:A 358 66 0.0386 0.0587 0.3182 2.1
13 5xtg:B 233 49 0.0294 0.0687 0.3265 2.3
14 7mdl:A 474 109 0.0423 0.0485 0.2110 2.5 3bcb:A, 8g9z:A, 8g9z:B, 8g9z:C, 8g9z:D, 3hl2:A, 3hl2:B, 3hl2:C, 3hl2:D, 7l1t:A, 7mdl:B, 7mdl:C, 7mdl:D, 4zdl:A, 4zdl:B, 4zdo:A, 4zdo:B, 4zdo:C, 4zdo:D, 4zdp:A, 4zdp:B, 4zdp:C, 4zdp:D
15 7mq8:NH 1066 84 0.0423 0.0216 0.2738 3.0 7mqa:NH
16 7uqi:E 558 63 0.0276 0.0269 0.2381 3.3 7uqk:E
17 8a1d:A 533 199 0.0864 0.0882 0.2362 3.6 8a1d:B, 8a1d:C, 8a1d:D, 8a1d:E, 8a1d:F, 8a1d:G, 8a1d:H, 8a1d:I, 8a1d:J, 8a1d:K, 8a1d:L, 8a1d:M, 8a1d:N, 8a1d:O, 8a1d:P, 8a1s:A, 8a1s:B, 8a1s:C, 8a1s:D, 8a1s:E, 8a1s:F, 8a1s:G, 8a1s:H, 8a1s:I, 8a1s:J, 8a1s:K, 8a1s:L, 8a1s:M, 8a1s:N, 8a1s:O, 8a1s:P
18 2z02:A 242 54 0.0294 0.0661 0.2963 4.5 2yzl:A, 2z02:B
19 1jg8:D 344 87 0.0496 0.0785 0.3103 5.1 2fm1:A, 1jg8:A, 1jg8:B, 1jg8:C, 1lw4:D, 1lw4:B, 1lw4:C, 1lw4:A, 1lw5:A, 1lw5:D, 1lw5:C, 1lw5:B, 1m6s:A, 1m6s:D, 1m6s:C, 1m6s:B
20 3c4a:A 365 65 0.0312 0.0466 0.2615 8.1
21 7uqj:A 585 52 0.0239 0.0222 0.2500 8.6 7uqi:A, 7uqi:B, 7uqi:C, 7uqi:D, 7uqj:C, 7uqj:D, 7uqj:E, 7uqj:F, 7uqj:B, 7uqk:A, 7uqk:B, 7uqk:C, 7uqk:D
22 6hnu:B 480 68 0.0423 0.0479 0.3382 9.3 6hnu:A
23 6gnn:C 198 112 0.0533 0.1465 0.2589 9.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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