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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KQVTDLRSELLDSRFGAKSISTIAESKRFPLHEMRDDVAFQIINDELYLDGNARQNLATFCQTWDDENVHKLMDLSINKN
WIDKEEYPQSAAIDLRCVNMVADLWHAPAPKNGQAVGTNTIGSSEACMLGGMAMKWRWRKRMEAAGKPTDKPNLVCGPVQ
ICWHKFARYWDVELREIPMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYEFPQPLHDALDKFQADTGIDIDMHID
AASGGFLAPFVAPDIVWDFRLPRVKSISASGHKFGLAPLGCGWVIWRDEEALPQELVFNVDYLGGQIGTFAINFSRPAGQ
VIAQYYEFLRLGREGYTKVQNASYQVAAYLADEIAKLGPYEFICTGRPDEGIPAVCFKLKDGEDPGYTLYDLSERLRLRG
WQVPAFTLGGEATDIVVMRIMCRRGFEMDFAELLLEDYKASLKYLSDHP

The query sequence (length=449) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3fz6:E 464 449 1.0000 0.9677 1.0000 0.0 2dgk:A, 2dgk:B, 2dgk:C, 2dgk:D, 2dgk:E, 2dgk:F, 2dgl:A, 2dgl:B, 2dgl:C, 2dgl:D, 2dgl:E, 2dgl:F, 2dgm:A, 2dgm:B, 2dgm:C, 2dgm:D, 2dgm:E, 2dgm:F, 3fz6:A, 3fz6:B, 3fz6:C, 3fz6:D, 3fz6:F, 3fz8:A, 3fz8:B, 3fz8:C, 3fz8:D, 3fz8:E, 3fz8:F, 1pmm:A, 1pmm:B, 1pmm:C, 1pmm:D, 1pmm:E, 1pmm:F, 1pmo:A, 1pmo:B, 1pmo:C, 1pmo:D, 1pmo:E, 1pmo:F, 1xey:A, 1xey:B
2 7x4y:E 459 434 0.4432 0.4336 0.4585 1.71e-133 7x4l:A, 7x4l:F, 7x4l:B, 7x4l:E, 7x4l:C, 7x4l:D, 7x4y:A, 7x4y:C, 7x4y:B, 7x4y:D, 7x4y:F, 7x51:A, 7x51:B, 7x51:C, 7x51:D, 7x51:F, 7x51:E, 7x52:A, 7x52:C, 7x52:B, 7x52:E, 7x52:D, 7x52:F
3 5gp4:A 441 440 0.4276 0.4354 0.4364 1.93e-131 5gp4:C, 5gp4:B
4 5k1r:B 440 337 0.1871 0.1909 0.2493 2.47e-22 5k1r:A
5 4q6r:B 444 332 0.1737 0.1757 0.2349 3.85e-16 4q6r:A
6 5eud:A 454 444 0.2361 0.2335 0.2387 5.70e-16 5eud:B, 5eue:A, 5eue:B, 3mad:A, 3mad:B, 3mau:A, 3mau:B, 3mau:C, 3mau:D, 3mbb:A, 3mbb:B
7 3mc6:A 426 339 0.1693 0.1784 0.2242 6.76e-16 3mc6:C
8 3f9t:A 394 377 0.1960 0.2234 0.2334 2.72e-10 3f9t:B, 6ldr:A, 6lds:A, 6ldt:A
9 8jij:A 411 122 0.0935 0.1022 0.3443 1.95e-08 8jik:A
10 8jg7:E 409 124 0.0824 0.0905 0.2984 1.29e-04 8jg7:A, 8jg7:C, 8jg7:D
11 6khn:A 490 151 0.0958 0.0878 0.2848 0.001 6khn:B, 6kho:A, 6kho:B, 6khp:A, 6khp:B
12 2okk:A 483 192 0.1136 0.1056 0.2656 0.003
13 6jtk:B 346 65 0.0468 0.0607 0.3231 0.034 6jtk:A, 6jtk:C, 6jtk:F, 6jtk:D, 6jtk:E
14 6eew:A 479 125 0.0846 0.0793 0.3040 0.30 6eew:B, 6eew:C, 6eew:D
15 7cim:A 524 100 0.0646 0.0553 0.2900 1.1 7cig:A, 7cig:B, 7cii:A, 7cii:B, 7cij:A, 7cij:B, 7cim:B
16 2q6v:A 370 71 0.0557 0.0676 0.3521 1.6 3cv3:A
17 6wlf:B 434 65 0.0401 0.0415 0.2769 2.3 6wlf:A
18 1orb:A 293 88 0.0512 0.0785 0.2614 2.6
19 8i16:A 639 92 0.0535 0.0376 0.2609 2.9
20 4obv:C 471 161 0.0980 0.0934 0.2733 3.1 4obu:E, 4obu:A, 4obu:U, 4obu:G, 4obu:H, 4obu:F, 4obu:B, 4obu:C, 4obv:D, 4obv:B, 4obv:A
21 1t3k:A 132 59 0.0334 0.1136 0.2542 6.6
22 5ngl:B 454 46 0.0334 0.0330 0.3261 8.4 5ngl:A, 5ngl:C
23 7kc0:A 1004 53 0.0356 0.0159 0.3019 8.6 3iay:A, 6p1h:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218