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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIPVYEQQKSVFSKYFERHGYRV
TGISGATAENVPVEQIVENNDIIILTPQILVNNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGP
LPQVIGLTASVGVGDAKNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMRD
TESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICKALFLYTSHLRKYNDALIISEHARMK
DALDYLKDFFSNVRAAGFDEIEQDLTQRFEEKLQELESVSRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVD
ALKNWIEGNPKLSFLKPGILDHNILIATSVAQCNLVILYEYVGRARGSKCFLLTSNAGVIEKEQINMYKEKMMNDSILRL
QTWDEAVFREKILHIQTHEKFIRDSQEKPKPVPDKENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHP
KPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAEM

The query sequence (length=635) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8g7t:A 647 646 1.0000 0.9815 0.9830 0.0 4ay2:A, 4bpb:A, 8dvr:A, 8g7u:A, 8g7u:C, 8g7v:A, 8g7v:C, 8scz:A, 8sd0:A, 7tnx:A, 7to1:A, 2ykg:A, 3zd6:A
2 8dvs:A 682 681 0.9984 0.9296 0.9310 0.0 7bah:A, 7bah:B, 7bai:A, 7bai:B, 7bai:E, 8dvu:A, 5f9f:A, 5f9f:C, 5f9f:E, 5f9f:G, 5f9f:I, 5f9f:K, 7jl1:A, 6kyv:B, 6kyv:D, 6kyv:F, 6kyv:H, 6kyv:J, 6kyv:L, 3lrn:A, 3lrn:B, 3lrr:A, 3lrr:B, 7mk1:A, 7mk1:B, 3ncu:A, 3ncu:B, 3og8:A, 3og8:B, 2qfb:A, 2qfb:B, 2qfb:C, 2qfb:D, 2qfb:E, 2qfb:F, 2qfb:G, 2qfb:H, 2qfb:I, 2qfb:J, 7tny:A, 7tnz:A, 7to0:A, 7to2:A
3 5f9h:G 653 665 0.9764 0.9495 0.9323 0.0 5e3h:A, 5f98:A, 5f98:C, 5f98:E, 5f98:G, 5f98:I, 5f98:K, 5f9h:A, 5f9h:C, 5f9h:E, 5f9h:I, 5f9h:K, 6gpg:A, 7jl3:A, 7jl3:C, 7jl3:E
4 3zd7:A 623 641 0.9512 0.9695 0.9423 0.0 8g7t:C
5 3tbk:A 524 526 0.6142 0.7443 0.7414 0.0
6 4a36:A 523 544 0.4441 0.5392 0.5184 0.0 4a36:B
7 5jc7:A 641 679 0.3417 0.3385 0.3196 1.01e-100
8 7jl0:A 662 683 0.3685 0.3535 0.3426 5.60e-100 7jl2:A, 7jl2:C, 7jl2:E
9 5jc3:A 668 695 0.3559 0.3383 0.3252 2.92e-99 5jc3:B, 5jc7:B, 5jcf:A, 5jcf:B, 5jch:A, 5jch:B
10 7bkp:A 689 700 0.3528 0.3251 0.3200 7.66e-96 6g19:A, 6gjz:A, 6gkh:A, 6gkm:A, 6h66:A, 7nic:A, 7niq:B
11 6h61:A 660 684 0.3543 0.3409 0.3289 1.45e-95 6g1s:A, 6g1x:A, 7nga:A
12 4gl2:A 617 669 0.3606 0.3712 0.3423 3.26e-94 4gl2:B
13 7bkq:A 640 682 0.3465 0.3438 0.3226 1.54e-87
14 5jb2:A 670 686 0.3134 0.2970 0.2901 7.57e-84 5jaj:A, 5jbg:A
15 5jbj:A 627 682 0.3008 0.3046 0.2801 2.65e-73
16 8t5s:A 693 721 0.3134 0.2872 0.2760 1.64e-58
17 4a2v:A 122 119 0.0976 0.5082 0.5210 1.38e-34 4a2x:A, 4a2x:C, 4a2x:B, 4a2x:D
18 7eld:A 1137 220 0.1039 0.0580 0.3000 3.18e-14 7ele:A
19 5zal:A 1314 196 0.0929 0.0449 0.3010 5.11e-13 2eb1:A, 2eb1:B, 2eb1:C, 4ngd:A, 5zam:A
20 7yym:A 1281 174 0.0866 0.0429 0.3161 9.25e-13 4ngb:A, 4ngc:A, 4ngg:A, 4nh3:A, 4nh5:A, 4nh6:A, 7yyn:A, 7zpi:A, 7zpj:A, 7zpk:A
21 7w0b:A 1586 183 0.0850 0.0340 0.2951 8.51e-12 7w0d:F
22 8hf0:A 1561 183 0.0850 0.0346 0.2951 9.56e-12 8hf0:D, 8hf1:A, 8hf1:D, 8hf1:G, 7w0a:A, 7w0a:E, 7w0c:A, 7w0d:A, 7w0e:A, 7w0f:A
23 7v6c:A 1540 182 0.0835 0.0344 0.2912 3.94e-11
24 2rqb:A 135 102 0.0488 0.2296 0.3039 9.65e-11 3ga3:A
25 5v9x:A 772 169 0.0772 0.0635 0.2899 4.13e-08
26 3eqt:B 142 118 0.0551 0.2465 0.2966 4.62e-08 3eqt:A, 2rqa:A
27 6qv4:A 1666 125 0.0567 0.0216 0.2880 2.29e-06 6qv3:A
28 6qv4:A 1666 178 0.0661 0.0252 0.2360 0.035 6qv3:A
29 2zja:A 700 162 0.0630 0.0571 0.2469 8.42e-05 2zj5:A
30 9bha:A 793 166 0.0630 0.0504 0.2410 2.95e-04 5a9f:A, 5aga:A, 9bh8:A, 9bh8:B, 9bh9:A, 9bh9:B, 9bha:B, 9c5q:C, 9c5q:A
31 9asj:A 741 166 0.0630 0.0540 0.2410 3.71e-04 9asj:B, 9bp9:A, 9bp9:C, 9bpa:A, 9bpa:C, 9bpa:E, 9bpa:G
32 5gan:B 1781 167 0.0661 0.0236 0.2515 0.001 4bgd:A, 5gao:B, 5gap:B, 5nrl:B, 5zwm:D, 5zwo:D
33 8w0a:C 636 130 0.0535 0.0535 0.2615 0.002 8w0a:A
34 4kbf:A 365 127 0.0551 0.0959 0.2756 0.003 2gxq:A, 2gxs:A, 2gxs:B, 2gxu:A, 3mwk:B, 3mwl:B, 3nbf:A, 3nbf:B, 3nbf:C, 3nbf:D
35 4kbf:A 365 77 0.0394 0.0685 0.3247 2.8 2gxq:A, 2gxs:A, 2gxs:B, 2gxu:A, 3mwk:B, 3mwl:B, 3nbf:A, 3nbf:B, 3nbf:C, 3nbf:D
36 8arp:C 445 136 0.0535 0.0764 0.2500 0.004 8arp:A, 8arp:B, 8arp:D, 8arp:E, 8arp:F
37 8dfv:A 1664 246 0.0724 0.0276 0.1870 0.005
38 8dga:A 1629 246 0.0724 0.0282 0.1870 0.005
39 8dg5:A 1635 246 0.0724 0.0281 0.1870 0.005 8dg7:A
40 7zpq:CA 1742 178 0.0724 0.0264 0.2584 0.006 7zrs:CA, 7zuw:CA
41 7zpq:CA 1742 161 0.0677 0.0247 0.2671 0.009 7zrs:CA, 7zuw:CA
42 5yzg:D 1908 125 0.0472 0.0157 0.2400 0.010 6ahd:D, 8bc8:B, 8bc9:B, 8bca:B, 8bcb:B, 8bcc:B, 8bcd:B, 8bce:B, 8bcf:B, 8bcg:B, 8bch:B, 7bdi:B, 7bdj:B, 7bdk:B, 7bdl:B, 4f92:B, 4f93:B, 6ff7:r, 8h6k:5D, 8h6l:5D, 4kit:B, 5o9z:C, 7os1:B, 8qo9:B, 8qzs:B, 5urj:A, 5urk:A, 5urm:A, 5urm:B, 5xjc:D
43 5yzg:D 1908 155 0.0614 0.0204 0.2516 0.012 6ahd:D, 8bc8:B, 8bc9:B, 8bca:B, 8bcb:B, 8bcc:B, 8bcd:B, 8bce:B, 8bcf:B, 8bcg:B, 8bch:B, 7bdi:B, 7bdj:B, 7bdk:B, 7bdl:B, 4f92:B, 4f93:B, 6ff7:r, 8h6k:5D, 8h6l:5D, 4kit:B, 5o9z:C, 7os1:B, 8qo9:B, 8qzs:B, 5urj:A, 5urk:A, 5urm:A, 5urm:B, 5xjc:D
44 8vxa:A 1139 118 0.0488 0.0272 0.2627 0.014 8vxc:A
45 8vxy:B 1161 118 0.0488 0.0267 0.2627 0.014
46 4ovy:A 305 96 0.0362 0.0754 0.2396 0.036
47 6p4f:C 436 158 0.0630 0.0917 0.2532 0.16 6p4f:A, 6p4w:A
48 2iw3:B 980 54 0.0252 0.0163 0.2963 0.16 7b7d:EF, 2iw3:A, 2iwh:A, 2iwh:B
49 8i9z:CE 465 110 0.0409 0.0559 0.2364 0.17 8i9p:CE, 8i9r:CE, 8i9t:CE, 8i9v:CE, 8i9w:CE, 8i9x:CE, 8i9y:CE, 8ia0:CE
50 6yw5:HH 160 80 0.0441 0.1750 0.3500 0.17 6ywe:HH, 6ywx:HH, 6ywy:HH
51 7ase:f 1523 138 0.0551 0.0230 0.2536 0.19 7ask:F
52 3ber:A 220 135 0.0535 0.1545 0.2519 0.32
53 8bic:B 323 121 0.0488 0.0960 0.2562 0.35 8bic:A
54 7wix:B 576 65 0.0315 0.0347 0.3077 0.53 7wiw:B
55 5gju:A 199 132 0.0520 0.1658 0.2500 1.0
56 8fkv:NI 647 121 0.0535 0.0526 0.2810 1.0 8fkt:NI, 8fku:NI, 8fkw:NI, 8fkx:NI, 8fky:NI
57 7nha:B 735 104 0.0362 0.0313 0.2212 1.2 8bek:B, 7nhx:B, 7nik:B, 7nil:B, 7nir:B, 7nis:B, 7nj3:B, 7nj4:B, 7nj5:B, 7nj7:B, 7nk1:B, 7nk2:B, 7nk4:B, 7nk6:B, 7nk8:B, 7nka:B, 7nkc:B, 7nki:B, 7nkr:B, 8pm0:B, 8pnp:B, 8poh:F, 7qtl:B, 6qx3:B, 6qx8:B, 6qx8:F, 6qxe:B, 6qxe:F, 7r0e:B, 8r60:B, 8r65:B, 7z4o:EEE, 7z4o:BBB, 7zpl:B, 7zpl:E
58 3iuy:A 213 136 0.0646 0.1925 0.3015 1.3 3iuy:B
59 7cha:I 262 66 0.0299 0.0725 0.2879 1.5 7ch8:I, 7ch8:J, 7cha:J
60 6yxy:EB 663 142 0.0488 0.0468 0.2183 1.5 7aoi:XB, 6yxx:EB
61 8tbx:A 458 191 0.0756 0.1048 0.2513 1.6
62 2p6r:A 683 129 0.0457 0.0425 0.2248 1.8
63 6md3:C 180 63 0.0283 0.1000 0.2857 1.9 6md3:A, 6md3:B, 6md3:D, 6md3:E, 6md3:F
64 7mdi:E 353 77 0.0378 0.0680 0.3117 2.1 7mdi:G, 7mdi:F, 7mdi:H
65 3dkp:A 240 117 0.0488 0.1292 0.2650 2.2
66 5dtu:A 404 126 0.0457 0.0718 0.2302 2.3
67 8h69:B 754 106 0.0362 0.0305 0.2170 2.5 7ni0:B, 8pnq:B, 8r3k:B, 8r3l:B, 6rr7:B
68 3in6:A 147 35 0.0236 0.1020 0.4286 2.6 3in6:B
69 7uzf:C 602 119 0.0441 0.0465 0.2353 3.0 9b8p:A, 9brd:A, 7khr:C, 7u4t:B, 7u8p:C, 7u8q:B, 7u8r:A, 7unf:M, 7uzg:C, 7uzh:B, 7uzi:B, 7uzj:C, 7uzk:C, 6vq6:C, 6vq7:B, 6vq8:A, 6vq9:C, 6vqa:B, 6vqb:A, 6wlz:C, 6wm2:C, 6wm3:B, 6wm4:A, 6xbw:C, 6xby:A
70 4pj3:A 1335 53 0.0268 0.0127 0.3208 3.1 7a5p:U, 6icz:Q, 6id1:Q, 7w59:Q, 7w5a:Q, 7w5b:Q, 5xjc:Q
71 7am2:BW 447 104 0.0346 0.0492 0.2115 3.5
72 8z0f:A 549 23 0.0157 0.0182 0.4348 3.6 8z0f:B
73 4ljy:A 451 134 0.0488 0.0687 0.2313 4.0 7oqb:p, 7oqe:p
74 8z9x:B 567 23 0.0157 0.0176 0.4348 4.2 8z9x:A
75 3d31:A 348 42 0.0252 0.0460 0.3810 4.5 3d31:B
76 1t3n:A 388 35 0.0236 0.0387 0.4286 4.5 2alz:A, 2dpi:A, 2dpj:A, 4ebc:A, 4ebd:A, 4ebe:A, 3epg:A, 3epi:A, 4eyh:B, 4eyi:B, 2fll:A, 2fln:A, 2flp:A, 4fs1:A, 4fs2:A, 3g6v:A, 3g6x:A, 3g6y:A, 3gv5:B, 3gv5:D, 3gv7:B, 3gv8:B, 3h40:A, 3h4b:A, 3h4d:A, 5kt2:A, 5kt3:A, 5kt4:A, 5kt5:A, 5kt6:A, 5kt7:A, 3ngd:A, 3osn:A, 3q8p:B, 3q8q:B, 3q8r:B, 3q8s:B, 1t3n:B, 5ulw:A, 5ulx:A, 1zet:A
77 8v87:3 656 120 0.0425 0.0412 0.2250 4.6 8v84:3
78 7fse:A 1040 51 0.0268 0.0163 0.3333 5.0 8ofb:A, 3oiy:A, 3p4x:A
79 4ddt:A 1102 51 0.0268 0.0154 0.3333 5.1 4ddu:A, 4ddv:A, 4ddv:B, 4ddw:A, 4ddx:A, 4ddx:B, 7fsf:A
80 1gl9:B 1020 122 0.0472 0.0294 0.2459 5.2 1gl9:C
81 2hox:B 427 115 0.0425 0.0632 0.2348 6.2 2hor:A, 2hox:C, 2hox:A, 2hox:D, 1lk9:B, 1lk9:A
82 7pmq:C 458 135 0.0583 0.0808 0.2741 7.6 7pli:A, 7pli:B, 7pli:J, 7pli:E, 7pli:F, 7pli:I, 7pmm:A, 7pmm:B, 7pmq:D, 7pmq:A, 7pmq:B
83 6o5f:A 417 139 0.0504 0.0767 0.2302 7.9 6o5f:B
84 8i54:A 1113 47 0.0220 0.0126 0.2979 8.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218