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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KPNILFIITDDHAYQTLGTGNNDSPVALPNFNKLGRQGMVFDRSYCANSLCGPSRACILTGRHSHMNGFVFNGQRPLDGS
QPTYPKMLQKAGYQTGLFGKWHLESDPTGFDTWEIFPGQGSYYNPDFISLKPDGKRQTKRFPGYATDVVTDKSIQWLGNR
DKNKPFLLVVGHKAPHRAWCPALRHLGKVDTSSMTPPANFHDDYANRPEFLKKNQQTVANHMAIYSDLKVLKDQVPEEMR
KSIVSPGYGWDLGELNRMTPEEKKTWTDYYAKRTKSLVDGMKSGKLKDPKAFAEWKWHAYMEDYLGCLLSVDDSIGRLME
YLDKEGIAKDTLVIYCGDQGFYMGEHGMYDKRWIFEESLRMPLIMRWPGKIPAGIRNNTMVQNIDYAPTIVSAAGADTPE
NMNTFQGVSLLPTAFTGKTPDNWRDAIYYCFYENPGEHNAPRHDGIRTDRYTLSYIWTSDEWMLFDMKKDPMQMKNVIDD
PAYKTTVEQLKKRYHELRKTYKVPENSPGGKGTPIPKFDASW

The query sequence (length=522) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7ebp:A 526 522 1.0000 0.9924 1.0000 0.0 7ebp:B, 7ebq:A
2 5g2v:A 494 517 0.4291 0.4534 0.4333 4.24e-141
3 7p24:AAA 494 504 0.4080 0.4312 0.4226 1.27e-135
4 7lj2:A 507 534 0.3602 0.3708 0.3521 8.83e-96 7lha:A, 7lha:B, 7lj2:B
5 7sno:A 506 532 0.3180 0.3281 0.3120 1.42e-80
6 6pt4:B 473 530 0.2682 0.2960 0.2642 1.95e-32 6pt4:A, 6pt6:B, 6pt6:A, 6pt9:A, 6pt9:B, 6ptk:A, 6ptk:B, 6ptk:C, 6ptk:D
7 6j66:B 476 510 0.2471 0.2710 0.2529 2.40e-32 6j66:A
8 4upl:A 555 535 0.2490 0.2342 0.2430 2.06e-29 4upl:C
9 2vqr:A 512 548 0.2567 0.2617 0.2445 4.32e-26
10 7oz8:AAA 474 528 0.2529 0.2785 0.2500 4.44e-25
11 7pth:A 517 497 0.2318 0.2340 0.2435 2.23e-24 6fny:A, 6fny:B, 6fny:C, 6fny:D, 6fny:E, 6fny:F, 6fny:G, 6fny:H, 6g5z:A, 6g5z:B, 6g5z:C, 6g5z:D, 6g60:A, 6g60:B, 6g60:C, 6g60:D, 7pth:B, 7pth:C, 7pth:D, 7ptj:A, 7ptj:B, 7ptj:C, 7ptj:D
12 4uph:A 504 529 0.2452 0.2540 0.2420 7.81e-23 4uph:B, 4uph:C, 4uph:D
13 7all:AAA 498 551 0.2490 0.2610 0.2359 2.93e-22
14 7ana:AAA 475 473 0.2146 0.2358 0.2368 8.07e-21 7ana:BBB, 7anb:AAA, 7anb:BBB
15 2w8s:B 513 202 0.1207 0.1228 0.3119 1.25e-20 2w8s:A, 2w8s:C, 2w8s:D
16 6hr5:A 376 186 0.1149 0.1596 0.3226 1.06e-19
17 6hr5:A 376 253 0.1379 0.1915 0.2846 2.29e-19
18 6b0j:A 452 210 0.1245 0.1438 0.3095 1.50e-19 6b0j:B, 6b0j:C, 6b0k:A, 6b0k:B, 6b0k:C, 6b1v:A, 6b1v:B, 6b1v:C, 6bia:A, 6bia:B, 6bia:C
19 6b0j:A 452 179 0.0881 0.1018 0.2570 1.05e-11 6b0j:B, 6b0j:C, 6b0k:A, 6b0k:B, 6b0k:C, 6b1v:A, 6b1v:B, 6b1v:C, 6bia:A, 6bia:B, 6bia:C
20 4cys:A 534 375 0.1686 0.1648 0.2347 9.81e-18 5aj9:A, 5aj9:B, 4cxk:A, 4cxk:B, 4cxs:A, 4cxs:B, 4cxu:A, 4cxu:B, 4cyr:A, 4cyr:B, 4cys:B, 1hdh:A, 1hdh:B
21 7an1:AAA 483 226 0.1149 0.1242 0.2655 5.56e-17 7oqd:AAA
22 7an1:AAA 483 207 0.1015 0.1097 0.2560 1.43e-12 7oqd:AAA
23 6psm:C 448 208 0.1188 0.1384 0.2981 1.54e-16 6prm:A, 6prm:B, 6prm:C, 6prm:D, 6psm:A, 6psm:B, 6psm:D, 6psm:E, 6psm:F, 6pso:B, 6pso:A
24 6psm:C 448 132 0.0632 0.0737 0.2500 5.06e-04 6prm:A, 6prm:B, 6prm:C, 6prm:D, 6psm:A, 6psm:B, 6psm:D, 6psm:E, 6psm:F, 6pso:B, 6pso:A
25 6ust:C 464 208 0.1284 0.1444 0.3221 5.69e-16 6ust:A, 6ust:B, 6ust:D
26 6ust:C 464 188 0.0939 0.1056 0.2606 2.96e-11 6ust:A, 6ust:B, 6ust:D
27 4fdi:A 494 209 0.1149 0.1215 0.2871 1.39e-15 4fdi:B, 4fdj:A, 4fdj:B
28 4fdi:A 494 128 0.0766 0.0810 0.3125 7.63e-10 4fdi:B, 4fdj:A, 4fdj:B
29 7stt:A 445 197 0.0977 0.1146 0.2589 1.69e-15 7stu:A, 7stv:A
30 7stt:A 445 193 0.1149 0.1348 0.3109 3.77e-13 7stu:A, 7stv:A
31 4upi:A 548 198 0.1054 0.1004 0.2778 2.67e-15
32 4upi:A 548 115 0.0709 0.0675 0.3217 1.79e-09
33 8di0:B 426 197 0.1073 0.1315 0.2843 5.93e-15
34 8di0:B 426 182 0.1015 0.1244 0.2912 2.60e-14
35 7oze:AAA 487 523 0.2433 0.2608 0.2428 1.62e-13 7oze:EEE, 7oze:FFF, 7oze:GGG
36 7ozc:AAA 485 107 0.0690 0.0742 0.3364 4.40e-12
37 7ozc:AAA 485 212 0.1015 0.1093 0.2500 2.62e-07
38 9fvt:A 519 127 0.0843 0.0848 0.3465 4.53e-12 9fvt:B, 9fvt:C, 9fvt:D
39 9fvt:A 519 122 0.0728 0.0732 0.3115 1.62e-10 9fvt:B, 9fvt:C, 9fvt:D
40 6s21:A 486 217 0.1207 0.1296 0.2903 1.00e-11 6s21:B, 6s21:C
41 6s21:A 486 224 0.1054 0.1132 0.2455 3.24e-09 6s21:B, 6s21:C
42 6s20:C 480 117 0.0785 0.0854 0.3504 1.20e-11
43 6s20:C 480 196 0.0805 0.0875 0.2143 8.00e-04
44 6hhm:A 459 130 0.0805 0.0915 0.3231 1.55e-11
45 6hhm:A 459 191 0.0958 0.1089 0.2618 1.39e-10
46 1fsu:A 475 201 0.1054 0.1158 0.2736 1.61e-11
47 1fsu:A 475 252 0.1034 0.1137 0.2143 0.072
48 6uss:A 485 190 0.0939 0.1010 0.2579 6.67e-11 6uss:B
49 6uss:A 485 233 0.1130 0.1216 0.2532 5.51e-05 6uss:B
50 8eg3:A 554 234 0.1207 0.1137 0.2692 1.09e-10 1p49:A
51 8eg3:A 554 115 0.0728 0.0686 0.3304 3.37e-09 1p49:A
52 7oza:CCC 488 183 0.0881 0.0943 0.2514 1.69e-10 7oza:AAA
53 7oza:CCC 488 232 0.1073 0.1148 0.2414 6.14e-05 7oza:AAA
54 7aj0:A 501 278 0.1341 0.1397 0.2518 6.10e-10 7aj0:B, 7aj0:C, 7aj0:D, 7aj0:E, 7aj0:F
55 7aj0:A 501 120 0.0709 0.0739 0.3083 4.60e-04 7aj0:B, 7aj0:C, 7aj0:D, 7aj0:E, 7aj0:F
56 1n2l:A 483 113 0.0805 0.0870 0.3717 8.98e-10 1auk:A, 1e1z:P, 1e2s:P, 1e33:P, 1e3c:P, 1n2k:A
57 1n2l:A 483 213 0.1054 0.1139 0.2582 8.98e-10 1auk:A, 1e1z:P, 1e2s:P, 1e33:P, 1e3c:P, 1n2k:A
58 7p26:AAA 484 121 0.0805 0.0868 0.3471 1.48e-09
59 7p26:AAA 484 114 0.0498 0.0537 0.2281 1.47e-04
60 7oz9:BBB 483 235 0.1207 0.1304 0.2681 2.68e-08 7oz9:AAA
61 7oz9:BBB 483 190 0.0939 0.1014 0.2579 4.76e-07 7oz9:AAA
62 3b5q:B 467 204 0.0958 0.1071 0.2451 8.55e-08 3b5q:A, 5g2t:A, 5g2t:B, 5g2t:C, 5g2t:D, 5g2u:A
63 3b5q:B 467 180 0.0843 0.0942 0.2444 1.78e-07 3b5q:A, 5g2t:A, 5g2t:B, 5g2t:C, 5g2t:D, 5g2u:A
64 5fql:A 507 116 0.0613 0.0631 0.2759 3.35e-07 6ioz:A
65 5fql:A 507 195 0.1034 0.1065 0.2769 8.57e-07 6ioz:A
66 4miv:A 484 187 0.0920 0.0992 0.2567 2.15e-05 4mhx:A, 4mhx:B, 4miv:B, 4miv:C, 4miv:D, 4miv:E, 4miv:F, 4miv:G, 4miv:H
67 4miv:A 484 41 0.0211 0.0227 0.2683 2.9 4mhx:A, 4mhx:B, 4miv:B, 4miv:C, 4miv:D, 4miv:E, 4miv:F, 4miv:G, 4miv:H
68 4miv:A 484 41 0.0268 0.0289 0.3415 4.9 4mhx:A, 4mhx:B, 4miv:B, 4miv:C, 4miv:D, 4miv:E, 4miv:F, 4miv:G, 4miv:H
69 6bnf:A 336 127 0.0670 0.1042 0.2756 0.003 6bnc:A, 6bnc:B, 6bnd:A, 6bnd:B
70 5yle:A 331 58 0.0326 0.0514 0.2931 0.026 5gov:B, 5gov:A, 5grr:A, 5k4p:A, 6li4:A, 6li4:B, 6li6:A, 6li6:B, 5lrm:A, 5lrn:A, 5lrn:B, 7yjp:A, 7yjp:B, 7yjq:A, 7yjq:B, 7yjr:A, 7yjr:B, 7yjs:A, 7yjs:B, 7yjt:A, 7yjt:B, 5ylc:A, 5ylf:A, 5zjv:A
71 6xlp:A 586 101 0.0536 0.0478 0.2772 0.043
72 6v8q:A 569 104 0.0536 0.0492 0.2692 0.099 6v8q:B, 6vat:A, 6vat:B, 6vat:C, 6vc7:A, 6vc7:B, 6vc7:C, 6vc7:D, 6vc7:E, 6vc7:F, 6vdf:A, 6vdf:C, 6vdf:D
73 6a7w:A 324 58 0.0307 0.0494 0.2759 0.11 6a7w:B, 5mx9:A, 6sut:A
74 2w5q:A 424 108 0.0479 0.0590 0.2315 0.31 2w5r:A, 2w5s:A, 2w5t:A
75 2w8d:B 421 109 0.0441 0.0546 0.2110 1.1 2w8d:A
76 7l48:A 522 136 0.0632 0.0632 0.2426 1.1 7c7l:A, 7l48:B, 7l49:A, 7l49:B
77 7bz3:C 335 132 0.0594 0.0925 0.2348 1.3 7bz3:D
78 8yk5:A 664 196 0.0805 0.0633 0.2143 1.8 8yk5:B
79 4uor:A 418 108 0.0498 0.0622 0.2407 2.5 4uoo:A, 4uoo:B, 4uoo:C, 4uoo:D, 4uoo:E, 4uor:B, 4uor:C, 4uor:D, 4uor:E, 4uor:F, 4uor:G, 4uor:H, 4uor:I, 4uor:J, 4uor:K
80 7qen:A 465 63 0.0326 0.0366 0.2698 2.8
81 6a4r:A 235 35 0.0268 0.0596 0.4000 2.9 6a4r:B
82 4k3v:B 278 129 0.0536 0.1007 0.2171 4.4 5hdq:A, 4nno:A
83 7duw:A 820 54 0.0383 0.0244 0.3704 4.4 7duw:B
84 8ghy:A 362 42 0.0287 0.0414 0.3571 5.1 8ghy:B
85 8av6:C 459 33 0.0249 0.0283 0.3939 5.9 8av6:A, 8av6:B, 6fhs:A, 6fhs:B, 6fhs:C, 6fml:A, 6fml:B, 6fml:C, 8oo7:A, 8oo7:B, 8oo7:C, 8ooc:A, 8ooc:B, 8ooc:C, 8oop:A, 8oop:B, 8oop:C, 8oor:A, 8oor:B, 8oor:C, 4wvy:A
86 4bed:A 1664 31 0.0249 0.0078 0.4194 6.7 4bed:C
87 4oxq:A 278 121 0.0536 0.1007 0.2314 7.3 4oxr:A, 4oxr:B
88 8bee:U 87 21 0.0192 0.1149 0.4762 9.5 7aqr:U, 7arb:U, 8bpx:U, 8bq5:U, 8bq6:U
89 6mvg:A 637 34 0.0230 0.0188 0.3529 9.5 6mvg:B, 6mvg:C
90 4k3v:A 253 113 0.0479 0.0988 0.2212 9.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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