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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KPNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLK
GSYIFTADMVRYLGDCGLPNVVDFIRITQVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVD
KPGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL

The query sequence (length=215) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6mxc:C 220 220 1.0000 0.9773 0.9773 1.14e-158 6aqo:A, 6aqo:B, 6aqo:C, 6aqo:D, 6aqo:E, 6aqo:F, 6ar9:A, 6ar9:B, 6ar9:C, 6ar9:D, 6ar9:E, 6ar9:F, 6mxb:A, 6mxb:B, 6mxb:C, 6mxb:D, 6mxb:E, 6mxb:F, 6mxc:A, 6mxc:B, 6mxc:D, 6mxc:E, 6mxc:F, 6mxd:A, 6mxd:B, 6mxd:C, 6mxd:D, 7scr:A, 7scr:C, 7scr:B, 7scr:D, 7scr:E, 7scr:F
2 8fx3:B 223 224 0.6140 0.5919 0.5893 4.82e-98 8fwy:A, 8fwy:B, 8fwz:A, 8fwz:B, 8fx0:A, 8fx0:B, 8fx1:A, 8fx1:B, 8fx2:A, 8fx2:B, 8fx3:A
3 6aps:A 185 196 0.3814 0.4432 0.4184 3.15e-46 6aps:B, 6apt:A, 6apt:B, 6apu:A, 6apu:B, 6apv:A, 6apv:B, 6apv:C, 6apv:D, 5jsq:A, 5jsq:B, 5jv5:A, 5jv5:B, 5k51:A, 5k51:B, 5k51:C, 5k51:D, 5kam:A, 5kam:C, 5kap:A, 5kap:B, 6mxg:A, 6mxg:B, 7sb7:A, 7sb7:B, 8tr1:A, 8tr1:B, 8tr1:C, 8tr1:D, 8ts4:A, 8ts4:B
4 1p17:B 204 203 0.3721 0.3922 0.3941 1.03e-36 1i0i:A, 1i0i:B, 1i0l:A, 1i0l:B, 1i13:A, 1i13:B, 1i14:A, 1i14:B, 1p17:A, 1p17:C, 1p17:D, 1p18:A, 1p18:B, 1p19:A, 1p19:B, 1p19:C, 1p19:D, 1tc1:A, 1tc1:B, 1tc2:A, 1tc2:B
5 7cmj:A 184 201 0.3209 0.3750 0.3433 2.56e-33 1pzm:A, 1pzm:B
6 1bzy:A 214 158 0.2651 0.2664 0.3608 1.66e-24 6bnj:A, 6bnj:B, 6bnj:C, 6bnj:D, 5brn:A, 5brn:C, 5brn:D, 1bzy:B, 1bzy:C, 1bzy:D, 1d6n:A, 1d6n:B, 3gep:A, 3gep:B, 3ggc:A, 3ggc:B, 3ggj:A, 3ggj:B, 5hia:A, 5hia:B, 5hia:C, 5hia:D, 1hmp:A, 1hmp:B, 4ijq:A, 4ijq:B, 4ijq:C, 4ijq:D, 4rab:A, 4rab:B, 4rab:C, 4rab:D, 4rac:A, 4rac:B, 4rac:C, 4rac:D, 4rad:A, 4rad:B, 4rad:C, 4rad:D, 4rad:E, 4rad:F, 4rad:G, 4rad:H, 4ran:A, 4ran:B, 4ran:C, 4ran:D, 4rao:A, 4rao:B, 4rao:C, 4rao:D, 4raq:A, 4raq:B, 4raq:C, 4raq:D, 7san:A, 7san:B, 7san:C, 7san:D, 8tpv:A, 8tpv:B, 8tpv:C, 8tpv:D, 5w8v:A, 5w8v:B, 5w8v:C, 5w8v:D
7 5brn:B 194 147 0.2651 0.2938 0.3878 2.18e-24 5bsk:A, 5bsk:B, 5bsk:C, 5bsk:D, 4kn6:A, 8tpy:A, 8tpy:B, 8tpy:C, 8tpy:D
8 2vfa:B 205 149 0.2558 0.2683 0.3691 2.46e-23 2vfa:A
9 4qyi:B 171 135 0.2140 0.2690 0.3407 6.37e-22 4qyi:A, 4qyi:C, 4qyi:D, 4qyi:E
10 3kb8:A 201 195 0.3023 0.3234 0.3333 9.11e-22 6d9r:A, 6d9r:B, 6d9s:A, 6d9s:B, 3h83:A, 3h83:B, 3kb8:B
11 1hgx:A 164 182 0.2651 0.3476 0.3132 1.84e-21
12 2geb:A 184 195 0.2651 0.3098 0.2923 4.72e-21 1r3u:A, 1r3u:B, 1yfz:A, 1yfz:B
13 2jbh:B 213 156 0.2419 0.2441 0.3333 6.96e-20 2jbh:A
14 5knx:B 176 142 0.2186 0.2670 0.3310 2.26e-18 1g9s:A, 1g9s:B, 1g9t:A, 1g9t:B, 1grv:B, 1grv:A, 1j7j:A, 1j7j:B, 5knr:A, 5knr:B, 5kns:A, 5kns:B, 5knt:A, 5knt:B, 5knu:A, 5knu:B, 5knv:A, 5knv:B, 5knx:A
15 5kny:B 187 197 0.2512 0.2888 0.2741 4.97e-18 5knp:A, 5knp:B, 5knp:C, 5knp:D, 5knq:A, 5knq:B, 5knq:C, 5knq:D, 5kny:A, 5kny:C, 5kny:D, 4rht:A, 4rht:B, 4rht:C, 4rht:D, 4rhu:A, 4rhu:B, 4rhu:C, 4rhu:D, 4rhu:E, 4rhu:F, 4rhx:A, 4rhx:B, 4rhx:C, 4rhx:D, 4rhy:A, 4rhy:B, 4rhy:C, 4rhy:D
16 6igs:B 167 135 0.2047 0.2635 0.3259 1.46e-17 6igs:A, 6igs:C, 6igs:D
17 3acc:A 166 133 0.2186 0.2831 0.3534 6.80e-17 3acd:A
18 4pfq:C 184 197 0.2372 0.2772 0.2589 1.35e-16 4pfq:A, 4pfq:B, 4pfq:D, 4pfq:E, 4pfq:F, 4pfq:G, 4pfq:H
19 5ipf:A 201 145 0.2233 0.2388 0.3310 1.71e-14 5ipf:B, 5ipf:C, 5ipf:D
20 6bo7:A 220 146 0.1907 0.1864 0.2808 8.77e-12 6bo7:B, 6bo7:C, 6bo7:D, 6bo7:E, 6bo7:F, 6bo7:G, 6bo7:H, 6bo7:I, 6bo7:J, 6bo7:K, 6bo7:L
21 1fsg:A 233 158 0.2093 0.1931 0.2848 3.02e-11 1dbr:A, 1dbr:B, 1dbr:D, 1fsg:C, 1qk3:A, 1qk3:B, 1qk3:C, 1qk3:D, 1qk4:A, 1qk4:B, 1qk4:C, 1qk4:D, 1qk5:A, 1qk5:B
22 3ozf:B 234 95 0.1488 0.1368 0.3368 3.40e-11 1cjb:A, 1cjb:B, 1cjb:C, 1cjb:D, 3ozf:A, 3ozf:C, 3ozf:D, 3ozg:A, 3ozg:B, 3ozg:C, 3ozg:D, 7tux:A, 7tux:B, 7tux:C, 7tux:D
23 5esw:A 190 153 0.2047 0.2316 0.2876 7.22e-10 5esx:A, 5esx:B
24 4trb:B 209 72 0.1023 0.1053 0.3056 0.001 4trc:A, 4trc:B, 4ts5:A, 4ts5:B, 4ts7:A, 4ts7:B
25 2igb:B 173 62 0.0930 0.1156 0.3226 0.002 2igb:A, 4p83:A, 4p83:B, 4p83:C, 4p83:D, 1xz8:A, 1xz8:B, 1xzn:A, 1xzn:B
26 1dqn:A 230 146 0.1395 0.1304 0.2055 0.007 1dqn:B, 1dqp:A, 1dqp:B
27 4p86:A 177 63 0.0837 0.1017 0.2857 0.007 4p86:B, 4p86:C, 4p86:D
28 4zfn:B 177 52 0.0930 0.1130 0.3846 0.008 5bqp:A, 5bqp:B, 5bqp:C, 5bqp:D, 4z1o:A, 4z1o:B, 4zfn:A
29 5iao:A 171 57 0.0744 0.0936 0.2807 0.041 5iao:C, 5iao:F
30 4gvh:A 341 75 0.1070 0.0674 0.3067 0.58 4gvh:B, 4gvi:B, 4hzm:A, 4hzm:B
31 4zev:A 290 66 0.0977 0.0724 0.3182 1.5 4qjb:A, 4qjb:B, 4zev:B, 4zew:A, 4zew:B, 4zex:A, 4zex:B
32 5vog:A 176 165 0.1721 0.2102 0.2242 1.8
33 2yyj:A 476 79 0.1023 0.0462 0.2785 1.8 2yyi:A, 2yyl:A, 2yym:A
34 8fnv:A 770 102 0.1209 0.0338 0.2549 2.3 8fnv:B, 8fnv:C, 8fnv:D, 8fnv:E, 8fnv:F, 8fnv:G, 8fnv:H, 8fnv:I, 8fnv:J, 8fnv:K, 8fnv:L, 8fnw:A, 8fnw:B, 8fnw:C, 8fnw:D, 8fnw:E, 8fnw:F, 8fnw:G, 8fnw:H, 8fnw:I, 8fnw:J, 8fnw:K, 8fnw:L
35 3d3s:A 159 45 0.0651 0.0881 0.3111 5.4 3d3s:C, 3d3s:D, 3d3s:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218