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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KPLPADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKAVISGNITKIKAVYDTNPAKFRTLQNILEVEKEMYGAEWPKVG
ATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRVNATKAYEMALKKYHGWIVQKIFQAALYAAPYKSDFLKALSKGQ
NVTEEECLEKIRLFLVNYTATIDVIYEMYTQMNAELNYKV

The query sequence (length=200) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4gxg:A 209 200 0.9950 0.9522 0.9950 4.16e-150 2bv7:A, 2euk:A, 2eum:A, 2evd:A, 2evl:A, 2evs:A, 2evs:E, 4gh0:A, 4ghp:A, 4ghs:A, 4ghs:B, 4gix:A, 4gjq:A, 4gjq:B, 4gvt:A, 4gxd:A, 4gxg:B, 4gxg:D, 4gxg:E, 4h2z:A, 3ric:A, 3rzn:A, 3s0i:A, 3s0k:A, 1sx6:A
2 5kdi:A 211 195 0.3600 0.3412 0.3692 1.57e-31 5kdi:B
3 4nti:A 202 167 0.2150 0.2129 0.2575 3.37e-09 4nt2:A, 4ntg:A, 4ntg:B, 4nti:B, 4nto:A, 4nto:B, 4nto:C
4 4kbr:B 207 144 0.1850 0.1787 0.2569 1.46e-05 4kbr:A, 4kbr:C, 4kbr:D, 4kbr:F, 4kbr:G, 4kbr:H
5 4k80:A 209 164 0.1950 0.1866 0.2378 9.92e-05 4k84:A, 4k84:B, 4k85:A, 4k85:B, 4k85:C, 4k85:D, 4k8n:A, 4k8n:E, 4k8n:B, 4k8n:C, 4k8n:D, 4k8n:F, 4kf6:A, 4kf6:B, 4kf6:C, 4kf6:D, 4kf6:E, 4kf6:F
6 8bja:A 1563 137 0.1650 0.0211 0.2409 0.34
7 8e0q:A 1689 136 0.1600 0.0189 0.2353 1.0 8d4x:A, 8e0q:B
8 8d4x:B 1669 136 0.1600 0.0192 0.2353 1.1 8c06:A, 8c06:D
9 6s83:A 400 47 0.0800 0.0400 0.3404 1.1 6s83:B, 6s83:C, 6s83:D, 6s83:E, 6s83:F, 6s83:G, 6s83:H
10 8ewi:A 1775 136 0.1600 0.0180 0.2353 1.2 8ewi:B, 8ewi:C, 8ewi:D
11 8p82:A 1596 142 0.1650 0.0207 0.2324 1.3 8p82:B
12 8bja:B 1638 145 0.1700 0.0208 0.2345 2.4
13 8q59:A 280 32 0.0600 0.0429 0.3750 2.6 8q57:A, 8q57:B, 8q59:B
14 6s6z:A 1083 87 0.1300 0.0240 0.2989 6.1 6s6z:D, 6s6z:B, 6s6z:H, 6s6z:F, 6s6z:G, 6s6z:E, 6s6z:C, 6sd0:A, 6sd0:B, 6sd0:C, 6sd0:D
15 8q5a:A 276 26 0.0600 0.0435 0.4615 7.1 8q58:A
16 6dbi:C 622 37 0.0450 0.0145 0.2432 7.8 6dbi:A, 6dbj:A, 6dbj:C, 6dbl:A, 6dbl:C, 6dbo:A, 6dbo:C, 6dbq:A, 6dbq:C, 6dbr:A, 6dbr:C, 6dbt:A, 6dbt:C, 6dbu:A, 6dbu:C, 6dbv:A, 6dbv:C, 6dbw:A, 6dbw:C, 6dbx:A, 6dbx:C, 3jbw:A, 3jbw:C, 3jbx:A, 3jbx:C, 3jby:A, 3jby:C
17 6oet:C 623 37 0.0550 0.0177 0.2973 9.9 6cg0:A, 6cg0:C, 6cij:A, 6cij:C, 6cik:A, 6cik:C, 6cil:A, 6cil:C, 6cim:A, 6cim:C, 3gna:A, 3gnb:A, 6oem:A, 6oem:C, 6oen:A, 6oen:C, 6oeo:A, 6oeo:C, 6oep:A, 6oep:C, 6oeq:A, 6oeq:C, 6oer:A, 6oer:C, 6oes:A, 6oes:C, 6oet:A, 6v0v:A, 4wwx:B, 4wwx:E, 6xnx:A, 6xnx:C, 6xny:A, 6xny:C, 6xnz:A, 6xnz:C, 5zdz:A, 5zdz:C, 5ze0:A, 5ze0:C, 5ze1:A, 5ze1:C, 5ze2:A, 5ze2:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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