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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSDQDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTP
VTSQLGGDSLFHRQSSYDIDKACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKRT
LALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFISPSQALINLPQEDFDSCKSSAQVD
WENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTFYEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALII
PEHYQRFLEGFLNSYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLETASKADPLGINGRHGL
AQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAASQNYRQLFDAETGYMRARDNQGNFHPDFSPY
SWGRDYAECSAIQATLGVLHDIPGLIQLMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSF
HIPYLFRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPSYDLGIPLFDHLRVYLAK
EDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAEQLTFTLSWLPSH

The query sequence (length=693) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5swi:B 693 693 1.0000 1.0000 1.0000 0.0 5swi:A, 5swi:C, 5swi:D
2 6dwo:A 712 702 0.4733 0.4607 0.4672 0.0 6dwo:B, 6dwo:C, 6dwo:D, 7fe1:A, 7fe1:B, 7fe1:C, 7fe1:D, 7fe2:A, 7fe2:B, 7fe2:C, 7fe2:D
3 2wvz:B 742 725 0.3348 0.3127 0.3200 2.51e-114 2wvx:A, 2wvx:B, 2wvx:C, 2wvx:D, 2wvz:A, 2wvz:C, 2wvz:D, 2ww0:A, 2ww0:B, 2ww0:C, 2ww0:D, 2ww0:E, 2ww0:F, 2ww0:G, 2ww0:H, 2ww1:A, 2ww1:B, 2ww1:C, 2ww1:D, 2ww3:A, 2ww3:B, 2ww3:C, 2ww3:D, 2ww3:E, 2ww3:F, 2wzs:A, 2wzs:B, 2wzs:C, 2wzs:D, 2wzs:E, 2wzs:F, 2wzs:G, 2wzs:H
4 2ww2:B 737 728 0.3261 0.3066 0.3104 1.64e-113
5 7nsn:A 1371 754 0.3102 0.1568 0.2851 3.73e-85 7nsn:B
6 7zgm:A 702 728 0.2814 0.2778 0.2679 1.07e-54
7 6f8z:A 715 717 0.2655 0.2573 0.2566 2.72e-52 6f8z:B, 6f8z:C, 6f90:A, 6f90:B, 6f90:C
8 6f92:A 760 741 0.2655 0.2421 0.2483 9.76e-41 6f91:A, 6f91:B, 6f91:C, 6f91:D, 6f91:E, 6f91:F, 6f91:G, 6f91:H, 6f92:B, 6f92:C, 6f92:D
9 4aq0:A 765 567 0.1688 0.1529 0.2063 3.86e-07 4aq0:B, 2xsg:A, 2xsg:B
10 8fvu:A 1361 90 0.0346 0.0176 0.2667 3.2 2vm5:A
11 1afs:A 319 36 0.0216 0.0470 0.4167 3.8 1afs:B, 1lwi:A, 1lwi:B
12 7pi3:H 321 68 0.0303 0.0654 0.3088 4.0 6mpv:A, 7phw:A, 7phw:D
13 6c9x:A 666 54 0.0231 0.0240 0.2963 4.4 6c9x:B, 6c9z:A, 6c9z:B, 6ca1:A, 6ca1:B, 6ca3:A, 6ca3:B, 3mkk:B, 3mkk:A, 3pha:A, 3pha:B, 3pha:C, 3pha:D, 3poc:B, 3poc:A
14 5yud:A 1238 75 0.0289 0.0162 0.2667 5.6
15 4uyr:A 188 106 0.0462 0.1702 0.3019 6.2 4uys:A
16 8cav:A 860 25 0.0144 0.0116 0.4000 6.4 8cav:B
17 7dnm:A 336 56 0.0317 0.0655 0.3929 8.8 7dnm:P, 7dnn:A, 7dnn:P

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218