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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQHAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQ
SHVPEHAQLGWALNCYTYFGELSRMTQYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDIAQRFNALYG
EIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVKKIKRAVTDSDEPPVVRYDVQNKAGVSNLLDI
LSAVTGQSIPELEKQFEGKMYGHLKGEVADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLKAVYEAIG
FVAKRHH

The query sequence (length=327) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8i1w:B 333 332 0.9939 0.9760 0.9789 0.0 8i1y:A, 8i1y:B, 8i1z:A, 8i1z:B, 8i27:A, 8i27:B, 8i2a:B, 8i2a:A, 8i2c:A, 8i2c:B, 8i2j:A, 8i2j:B, 8i2l:B, 8i2l:A, 8i2m:A, 8i2m:B, 8i4i:A, 8i4i:B, 5v0i:A, 5v0i:B
2 6dfu:A 332 332 0.7737 0.7620 0.7620 0.0 6dfu:B
3 3sz3:A 341 335 0.6667 0.6393 0.6507 8.29e-161
4 7cms:A 328 328 0.5596 0.5579 0.5579 5.49e-129 7cki:A, 7cms:B, 5dk4:A, 7eer:A, 7eer:B, 7eer:C, 7eer:D, 1i6k:A, 1i6l:A, 1i6m:A, 1m83:A, 1mau:A, 1maw:A, 1maw:B, 1maw:C, 1maw:D, 1maw:E, 1maw:F, 1mb2:A, 1mb2:B, 1mb2:C, 1mb2:D, 1mb2:E, 1mb2:F, 2ov4:A
5 3fi0:G 302 318 0.5229 0.5662 0.5377 3.83e-115 3fhj:A, 3fhj:B, 3fhj:E, 3fhj:F, 3fi0:A, 3fi0:B, 3fi0:C, 3fi0:D, 3fi0:E, 3fi0:F, 3fi0:H, 3fi0:I, 3fi0:J, 3fi0:K, 3fi0:L, 3fi0:M, 3fi0:N, 3fi0:O, 3fi0:P, 3fi0:Q, 3fi0:R
6 7elt:A 330 328 0.4985 0.4939 0.4970 9.56e-108 7ens:A, 7ent:A, 7ev2:A, 7ev3:A
7 3fhj:D 286 318 0.4985 0.5699 0.5126 5.48e-106 3fhj:C
8 5ekd:A 327 327 0.4281 0.4281 0.4281 1.68e-85 5ekd:B
9 2yy5:B 346 340 0.3945 0.3728 0.3794 6.71e-71 2yy5:A, 2yy5:C, 2yy5:D
10 3tzl:B 320 328 0.3792 0.3875 0.3780 8.21e-63 3tzl:A
11 2g36:A 322 336 0.3639 0.3696 0.3542 5.01e-51
12 5tew:A 333 328 0.3364 0.3303 0.3354 1.31e-50
13 6ncr:A 342 346 0.3364 0.3216 0.3179 3.86e-45 6ncr:B
14 2a4m:C 331 339 0.3180 0.3142 0.3068 3.02e-35 1yi8:C, 1yia:B, 1yid:B
15 3a04:A 367 231 0.1774 0.1580 0.2511 2.16e-08 3a05:A
16 3jxe:B 363 213 0.1407 0.1267 0.2160 4.54e-06 3jxe:A
17 3p0j:A 657 353 0.2599 0.1294 0.2408 1.98e-05 3p0h:B, 3p0i:B, 3p0j:B
18 2j5b:A 321 299 0.2355 0.2399 0.2575 2.74e-05 2j5b:B
19 7ror:B 362 245 0.1835 0.1657 0.2449 4.66e-05 7ror:A, 7ros:A, 7ros:B, 7rot:A, 7rot:B, 3vgj:A, 3vgj:B
20 5usf:A 682 337 0.2385 0.1144 0.2315 0.003 3p0h:A, 3p0i:A, 3p0j:C, 3p0j:D, 5usf:B
21 2cyb:A 319 223 0.1376 0.1411 0.2018 0.007 2cyb:B
22 3hv0:A 352 109 0.0856 0.0795 0.2569 0.008 3hv0:B
23 7sc6:A 349 333 0.2385 0.2235 0.2342 0.14 7scq:A, 7scq:B
24 4j75:A 374 80 0.0887 0.0775 0.3625 0.21 4j75:B, 4jfa:A, 4jfa:B, 4jfa:D
25 1h3f:B 406 95 0.0826 0.0665 0.2842 0.28 1h3f:A
26 1h3e:A 427 95 0.0826 0.0632 0.2842 0.31
27 7prb:B 438 62 0.0673 0.0502 0.3548 0.49 8ohw:AAA, 8ohw:BBB, 7pr9:A, 7pr9:B, 7prb:A
28 8i7j:P 123 104 0.0887 0.2358 0.2788 0.60 6fyx:P, 6fyy:P, 6gsm:P, 6gsn:P, 5it7:P, 5it9:P, 3j80:P, 3j81:P, 3jam:P, 3jap:P, 8rw1:P, 8s8d:P, 8s8e:P, 8s8f:P, 8s8g:P, 8s8h:P, 8s8i:P, 8s8j:P, 6uz7:P
29 3kt8:D 410 80 0.0734 0.0585 0.3000 0.62 3kt0:A, 3kt3:A, 3kt3:B, 3kt3:C, 3kt3:D, 3kt6:A, 3kt6:B, 3kt6:C, 3kt6:D, 3kt8:A, 3kt8:B, 3kt8:C
30 2e7u:A 424 113 0.0979 0.0755 0.2832 0.88
31 8c01:r 239 39 0.0489 0.0669 0.4103 1.9 8c00:r
32 8cbj:l 286 39 0.0489 0.0559 0.4103 1.9 6eml:r, 6fai:l, 6rbd:l, 6y7c:l
33 4pe5:D 727 88 0.0703 0.0316 0.2614 2.6 4pe5:B
34 9are:B 789 88 0.0703 0.0292 0.2614 3.0 9are:D, 9arf:B, 9arf:D, 9ari:B, 9ari:D, 9bib:B, 9bib:D, 6e7r:B, 6e7r:D, 6e7s:B, 6e7s:D, 6e7t:B, 6e7t:D, 6e7u:B, 6e7u:D, 6e7v:B, 6e7v:D, 6e7w:B, 6e7w:D, 6e7x:B, 6e7x:D, 5ewj:B, 5ewj:D, 5ewl:B, 5ewl:D, 5ewm:B, 5ewm:D, 8g18:B, 8g18:D, 3jpy:A, 3qel:B, 3qel:D, 3qem:B, 3qem:D, 7saa:B, 7saa:D, 7sac:B, 7sac:D, 6whu:B, 6whu:D, 6whv:B, 6whv:D, 6whw:B, 6whw:D, 6whx:B, 6whx:D
35 2cyc:A 371 187 0.1284 0.1132 0.2246 3.2 2cyc:B
36 5ujj:A 446 164 0.1162 0.0852 0.2317 3.3 2ake:A, 2azx:A, 2azx:B, 2dr2:A, 2quh:A, 2quh:B, 2qui:A, 2qui:B, 2quj:A, 2quj:B, 1r6t:A, 1r6u:A, 5ujj:B
37 4tlm:D 753 88 0.0673 0.0292 0.2500 3.6
38 4tll:D 757 88 0.0673 0.0291 0.2500 3.6 4tll:B, 4tlm:B, 5un1:B
39 5iov:B 798 88 0.0673 0.0276 0.2500 4.4 5iou:B, 5iou:D, 5iov:D, 5un1:D, 5un1:H
40 5w21:A 922 60 0.0550 0.0195 0.3000 4.8 7ysh:A, 7ysu:A, 7ysw:A
41 6sj8:A 305 49 0.0459 0.0492 0.3061 6.8 6sj8:B, 6sjn:A, 6sjo:A, 6sjr:A, 6sjr:B, 6sjs:A, 6sjs:B, 6sk4:A, 6sk4:B, 6sk4:C, 6sk4:D
42 5mrc:Q 284 66 0.0642 0.0739 0.3182 7.3 3j6b:Q, 5mre:Q, 5mrf:Q
43 2gjp:A 481 82 0.0612 0.0416 0.2439 7.7 2gjr:A, 1w9x:A
44 6z96:A 155 20 0.0398 0.0839 0.6500 8.6 6z92:A, 6z92:B, 6z93:A, 6z93:B, 6z94:A, 6z94:B, 6z96:B, 6zw9:A, 6zw9:B
45 8gna:A 1188 45 0.0428 0.0118 0.3111 9.5
46 7y80:A 1218 45 0.0428 0.0115 0.3111 9.6 8gu6:A
47 6vs4:A 223 75 0.0612 0.0897 0.2667 9.7 6vs4:B
48 7y84:A 1242 45 0.0428 0.0113 0.3111 9.9 7x7a:A, 7x7r:A, 7xc7:A, 7y83:A, 7y85:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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