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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KPIGVAVLGLGNVGSEVVRIIDESATDLAARIGAPLQLRGIGVRRVSADRGVPVELLTDNIEELVSRDDVDIVVELMGPV
EPARKAILTALEQGKSVVTANKALMSVSTGELAQAAEAAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVTRVAGIVNGTTN
YILSAMDSTGADYGDALAEASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTAADFASARALG
CTIKLLAICERLTSDDGHQSVSARVYPALVPLTHPLAAVNGAFNAVVVEAEAAGRLMFYGQGAGGAPTASAVMGDVVMAA
RNRVQGGRGPRESKYAKLPISPIGDIPTRYYVSMRVADRPGVLAAVATEFGNRSVSIAEVRQEGIDDGARLVVVTHKATD
AALSETVKALASLDVVQSVDSVIRMEGT

The query sequence (length=428) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6dzs:A 431 429 0.9977 0.9907 0.9953 0.0 6dzs:B, 6dzs:C, 6dzs:D
2 4pg7:A 402 322 0.3014 0.3209 0.4006 1.10e-64
3 6a0t:B 332 292 0.2570 0.3313 0.3767 1.55e-39 6a0s:B, 6a0s:A, 6a0t:A, 6a0u:B, 6a0u:A, 2ejw:A, 2ejw:B, 2ejw:E, 2ejw:F, 5xdf:A, 5xdf:B
4 5x9d:A 302 323 0.2173 0.3079 0.2879 5.94e-29 7f4c:A, 7f4c:B
5 4xb1:A 319 334 0.2266 0.3041 0.2904 2.22e-26 4xb1:B, 4xb2:A, 4xb2:B
6 3ing:A 319 244 0.1706 0.2288 0.2992 7.69e-19
7 3jsa:A 321 343 0.2103 0.2804 0.2624 4.12e-17
8 1ebf:A 358 126 0.0935 0.1117 0.3175 2.86e-11 1ebu:D, 1q7g:A, 1tve:A, 1tve:B
9 4o65:A 153 101 0.0724 0.2026 0.3069 0.92
10 1dap:A 320 76 0.0561 0.0750 0.3158 1.2 1dap:B, 2dap:A, 3dap:A, 3dap:B, 1f06:A, 1f06:B, 5loa:A, 5loa:B
11 8bja:A 1563 135 0.0888 0.0243 0.2815 3.0
12 7oni:H 380 48 0.0397 0.0447 0.3542 3.2
13 1e6v:A 545 66 0.0491 0.0385 0.3182 3.6 1e6v:D
14 6z3c:AAA 379 108 0.0724 0.0818 0.2870 3.6 6z3b:A, 6z3b:B, 6z3c:BBB
15 3jzd:A 354 30 0.0350 0.0424 0.5000 4.5 3jzd:B, 3jzd:C, 3jzd:D
16 5a8w:D 549 63 0.0467 0.0364 0.3175 5.0 5a8r:A, 5a8r:D, 5a8r:G, 5a8r:J, 5a8w:A, 5a8w:G, 5a8w:J
17 8h3v:G 314 62 0.0374 0.0510 0.2581 6.8 8h40:G
18 8d4x:B 1669 171 0.0958 0.0246 0.2398 8.2 8c06:A, 8c06:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218